المؤلفون: Scaletti, Emma Rose, 1987, Unterlass, Judith E., Almlöf, Ingrid, Koolmeister, Tobias, Vallin, Karl S., Kapsitidou, Despina, Tsuber, Viktoriia, Helleday, Thomas, Stenmark, Pål, 1976, Jemth, Ann-Sofie

المصدر: The FEBS Journal. 291(19):4301-4322

مصطلحات موضوعية: enzyme catalysis, hydrolysis, isoprene pyrophosphate, NUDT15, NUDT18

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-237705
https://doi.org/10.1111/febs.17202

المؤلفون: Karsten, Stella, Fiskesund, Roland, Zhang, Xing-Mei, Marttila, Petra, Sanjiv, Kumar, Pham, Therese, Rasti, Azita, Bräutigam, Lars, Almlöf, Ingrid, Marcusson-Ståhl, Maritha, Sandman, Carolina, Platzack, Björn, Harris, Robert A, Kalderén, Christina, Cederbrant, Karin, Helleday, Thomas, Warpman Berglund, Ulrika

المساهمون: Karolinska Institutet, Dept of Oncology-Pathology, Publisher, Karolinska Institutet, Inst för onkologi-patologi, Publisher

المصدر: Cell Death & Differentiation.

مصطلحات موضوعية: MEDICAL AND HEALTH SCIENCES, MEDICIN OCH HÄLSOVETENSKAP

وصف الملف: electronic

URL الوصول: http://hdl.handle.net/10616/47733

المؤلفون: Bonagas, Nadilly, Gustafsson, Nina M. S., Henriksson, Martin, Marttila, Petra, Gustafsson, Robert, 1988, Wiita, Elisée, Borhade, Sanjay, Green, Alanna C., Vallin, Karl S. A., Sarno, Antonio, Svensson, Richard, Göktürk, Camilla, Pham, Therese, Jemth, Ann-Sofie, Loseva, Olga, Cookson, Victoria, Kiweler, Nicole, Sandberg, Lars, Rasti, Azita, Unterlass, Judith E., Haraldsson, Martin, Andersson, Yasmin, Scaletti, Emma R., Bengtsson, Christoffer, Paulin, Cynthia B. J., Sanjiv, Kumar, Abdurakhmanov, Eldar, Pudelko, Linda, Kunz, Ben, Desroses, Matthieu, Iliev, Petar, Färnegårdh, Katarina, Krämer, Andreas, Garg, Neeraj, Michel, Maurice, Häggblad, Sara, Jarvius, Malin, Kalderén, Christina, Bögedahl Jensen, Amanda, Almlöf, Ingrid, Karsten, Stella, Zhang, Si Min, Häggblad, Maria, Eriksson, Anders, Liu, Jianping, Glinghammar, Björn, Nekhotiaeva, Natalia, Klingegård, Fredrik, Koolmeister, Tobias, Martens, Ulf, Llona-Minguez, Sabin, Moulson, Ruth, Nordström, Helena, Parrow, Vendela, Dahllund, Leif, Sjöberg, Birger, Vargas, Irene L., Vo, Duy Duc, Wannberg, Johan, Knapp, Stefan, Krokan, Hans E., Arvidsson, Per, Scobie, Martin, Meiser, Johannes, Stenmark, Pål, Warpman Berglund, Ulrika, Homan, Evert J., Helleday, Thomas

المصدر: Nature cancer. 3(2):156-172

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-203237
https://doi.org/10.1038/s43018-022-00331-y

المؤلفون: Zhang, Si Min, Rehling, Daniel, Jemth, Ann-Sofie, Throup, Adam, Landázuri, Natalia, Almlöf, Ingrid, Göttmann, Mona, Valerie, Nicholas C K, Borhade, Sanjay R, Wakchaure, Prasad, Page, Brent D G, Desroses, Matthieu, Homan, Evert J, Scobie, Martin, Rudd, Sean G, Berglund, Ulrika Warpman, Söderberg-Nauclér, Cecilia, Stenmark, Pål, Helleday, Thomas

المصدر: Cell Chemical Biology. 28(12):6-1702

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Gastroenterologi, Medical and Health Sciences, Clinical Medicine, Gastroenterology and Hepatology

URL الوصول: https://lup.lub.lu.se/record/000b115f-b385-4e21-a3f2-9ed83fbd4592
http://dx.doi.org/10.1016/j.chembiol.2021.06.001

المؤلفون: Valerie, Nicholas C. K., Sanjiv, Kumar, Mortusewicz, Oliver, Zhang, Si Min, Alam, Seher, Pires, Maria J., Stigsdotter, Hannah, Rasti, Azita, Langelier, Marie-France, Rehling, Daniel, Throup, Adam, Purewal-Sidhu, Oryn, Desroses, Matthieu, Onireti, Jacob, Wakchaure, Prasad, Almlöf, Ingrid, Boström, Johan, Bevc, Luka, Benzi, Giorgia, Stenmark, Pål, Pascal, John M., Helleday, Thomas, Page, Brent D. G., Altun, Mikael

المساهمون: Barncancerfonden, Stiftelsen Felix Mindus Bidrag till Leukemiforskningen, Loo och Hans Ostermans Stiftelse för Medicinsk Forskning, Karolinska Institutet, Cancerfonden, Novo Nordisk Fonden, Cancer Research Karolinska Institutet (KI) Blue Sky Grant, EC | Horizon 2020 Framework Programme, Alfred Österlunds Stiftelse, European Research Council, Gouvernement du Canada | Canadian Institutes of Health Research, Torsten Söderbergs Stiftelse, Svenska Sällskapet för Medicinsk Forskning, Michael Smith Foundation for Health Research, Science for Life Laboratory, Hållsten Foundation

المصدر: Nature Communications ; volume 15, issue 1 ; ISSN 2041-1723

الاتاحة: https://doi.org/10.1038/s41467-024-54415-7
https://www.nature.com/articles/s41467-024-54415-7.pdf
https://www.nature.com/articles/s41467-024-54415-7

المؤلفون: Zhang, Si Min, Paulin, Cynthia B.J., Shu, Huazhang, Yagüe-Capilla, Miriam, Michel, Maurice, Marttila, Petra, Ortis, Florian, Bwanika, Henri Colyn, Dirks, Christopher, Venkatram, Rajagopal Papagudi, Wiita, Elisée, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Hormann, Femke M., Koolmeister, Tobias, Linde, Erika, Lee, Sun, Llona-Minguez, Sabin, Haraldsson, Martin, Axelsson, Hanna, Strömberg, Kia, Homan, Evert J., Scobie, Martin, Lundbäck, Thomas, Helleday, Thomas, Rudd, Sean G.

المساهمون: Felix Mindus Foundation's contribution to leukemia research, Barncancerfonden, Stiftelsen Clas Groschinskys Minnesfond, Dr Åke Olsson's Foundation for Haematological Research, Åke Wiberg Stiftelse, Sjöbergstiftelsen, IMI, Cancerfonden, Vetenskapsradet, Stiftelsen Lars Hiertas Minne

المصدر: iScience ; volume 27, issue 2, page 108907 ; ISSN 2589-0042

الاتاحة: http://dx.doi.org/10.1016/j.isci.2024.108907
https://api.elsevier.com/content/article/PII:S2589004224001287?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2589004224001287?httpAccept=text/plain

المؤلفون: Sanjiv, Kumar, Calderón-Montaño, José Manuel, Pham, Therese M., Erkers, Tom, Tsuber, Viktoriia, Almlöf, Ingrid, Höglund, Andreas, Heshmati, Yaser, Seashore-Ludlow, Brinton, Danda, Akhilesh Nagesh, Gad, Helge, Wiita, Elisee, Göktürk, Camilla, Rasti, Azita, Friedrich, Stefanie, Centio, Anders, Estruch, Montserrat, Våtsveen, Thea Kristin, Struyf, Nona, Visnes, Torkild, Scobie, Martin, Koolmeister, Tobias, Henriksson, Martin, Wallner, Olov, Sandvall, Teresa, Lehmann, Sören, Theilgaard-Mönch, Kim, Garnett, Mathew J., Östling, Päivi, Walfridsson, Julian, Helleday, Thomas, Berglund, Ulrika Warpman

المصدر: Cancer Research. 81(22):5733-5744

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-199545
https://doi.org/10.1158/0008-5472.CAN-21-0061

المؤلفون: Hank, Emily C., D'Arcy-Evans, Nicholas, Scaletti, Emma Rose, Benítez-Buelga, Carlos, Wallner, Olov, Ortis, Florian, Zhou, Kaixin, Meng, Liuzhen, Calvo, Patricia, Almlöf, Ingrid, Wiita, Elisée, Kosenina, Sara, Krämer, Andreas, Long, Maeve, Jemth, Ann-Sofie, Dawson, Holly, Stewart, Josephine, Dickey, Adam, Astorga, Mikhael E., Varga, Marek, Homan, Evert J, Scobie, Martin, Knapp, Stefan, de Vega, Miguel, Sastre, Leandro, Stenmark, Pål, Helleday, Thomas, Michel, Maurice

الاتاحة: https://doi.org/10.26434/chemrxiv-2023-70gws-v4
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/677454d56dde43c908ed6d9f/original/nucleobase-catalysts-for-the-enzymatic-activation-of-8-oxoguanine-dna-glycosylase-1.pdf

المؤلفون: Visnes, Torkild, Benitez-Buelga, Carlos, Cázares-Körner, Armando, Sanjiv, Kumar, Hanna, Bishoy M. F., Mortusewicz, Oliver, Rajagopal, Varshni, Albers, Julian J., Hagey, Daniel W., Bekkhus, Tove, Eshtad, Saeed, Baquero, Juan Miguel, Masuyer, Geoffrey, Wallner, Olov, Müller, Sarah, Pham, Therese, Göktürk, Camilla, Rasti, Azita, Suman, Sharda, Torres-Ruiz, Raúl, Sarno, Antonio, Wiita, Elisée, Homan, Evert J., Karsten, Stella, Marimuthu, Karthick, Michel, Maurice, Koolmeister, Tobias, Scobie, Martin, Loseva, Olga, Almlöf, Ingrid, Unterlass, Judith Edda, Pettke, Aleksandra, Boström, Johan, Pandey, Monica, Gad, Helge, Herr, Patrick, Jemth, Ann-Sofie, El Andaloussi, Samir, Kalderén, Christina, Rodriguez-Perales, Sandra, Benitez, Javier, Krokan, Hans E., Altun, Mikael, Stenmark, Pål, Warpman Berglund, Ulrika, Helleday, Thomas

المصدر: Nucleic Acids Research. 48(21):12234-12251

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-191240
https://doi.org/10.1093/nar/gkaa1048

المؤلفون: Page, Brent D.G., Valerie, Nicholas C.K., Wright, Roni H.G., Wallner, Olov, Isaksson, Rebecka, Carter, Megan, Rudd, Sean G., Loseva, Olga, Jemth, Ann-Sofie, Almlöf, Ingrid, Font-Mateu, Jofre, Llona-Minguez, Sabin, Baranczewski, Pawel, Jeppsson, Fredrik, Homan, Evert, Almqvist, Helena, Axelsson, Hanna, Regmi, Shruti, Gustavsson, Anna-Lena, Lundbäck, Thomas, Scobie, Martin, Strömberg, Kia, Stenmark, Pål, Beato, Miguel, Helleday, Thomas

مصطلحات موضوعية: Càncer de pulmó, Desenvolupament de fàrmacs, Fàrmacs, Cáncer de pulmón, Desarrollo de fármacos, Fármacos, Lung cancer, Drug development, Drugs, 616.2

Time: 61

وصف الملف: application/pdf

Relation: Nature Communications; 9; Page, Brent D.G.; Valerie, Nicholas C.K.; Wright, Roni H.G. [et al.]. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nature Communications, 2018, 9, 250. Disponible en: . Fecha de acceso: 13 dic. 2021. DOI:10.1038/s41467-017-02293-7; http://hdl.handle.net/20.500.12328/3012; https://dx.doi.org/10.1038/s41467-017-02293-7

الاتاحة: https://hdl.handle.net/20.500.12328/3012
https://doi.org/10.1038/s41467-017-02293-7

المؤلفون: Hank, Emily C., D'Arcy-Evans, Nicholas, Scaletti, Emma Rose, Benítez-Buelga, Carlos, Wallner, Olov, Ortis, Florian, Zhou, Kaixin, Meng, Liuzhen, Calvo, Patricia, Almlöf, Ingrid, Wiita, Elisée, Kosenina, Sara, Krämer, Andreas, Long, Maeve, Jemth, Ann-Sofie, Dawson, Holly, Stewart, Josephine, Dickey, Adam, Astorga, Mikhael E., Varga, Marek, Homan, Evert J, Scobie, Martin, Knapp, Stefan, de Vega, Miguel, Sastre, Leandro, Stenmark, Pål, Helleday, Thomas, Michel, Maurice

الاتاحة: https://doi.org/10.26434/chemrxiv-2023-70gws-v3
https://chemrxiv.org/engage/api-gateway/chemrxiv/assets/orp/resource/item/663df266418a5379b0ecceb9/original/nucleobase-catalysts-for-the-enzymatic-activation-of-8-oxoguanine-dna-glycosylase-1.pdf

المؤلفون: Das, Ishani, Gad, Helge, Bräutigam, Lars, Pudelko, Linda, Tuominen, Rainer, Höiom, Veronica, Almlöf, Ingrid, Rajagopal, Varshni, Hansson, Johan, Helleday, Thomas, Egyházi Brage, Suzanne, Warpman Berglund, Ulrika

المصدر: Cell Death & Differentiation ; volume 27, issue 7, page 2081-2098 ; ISSN 1350-9047 1476-5403

الاتاحة: http://dx.doi.org/10.1038/s41418-019-0488-1
http://www.nature.com/articles/s41418-019-0488-1.pdf
http://www.nature.com/articles/s41418-019-0488-1

المؤلفون: Michel, Maurice, Homan, Evert J., Wiita, Elisée, Pedersen, Kia, Almlöf, Ingrid, Gustavsson, Anna-Lena, Lundbäck, Thomas, Helleday, Thomas, Warpman Berglund, Ulrika

المصدر: Frontiers in Chemistry ; volume 8 ; ISSN 2296-2646

الاتاحة: http://dx.doi.org/10.3389/fchem.2020.00443
https://www.frontiersin.org/article/10.3389/fchem.2020.00443/full

المؤلفون: Page, Brent D. G., Valerie, Nicholas C. K., Wright, Roni H. G., Wallner, Olov, Isaksson, Rebecka, Carter, Megan, Rudd, Sean G., Loseva, Olga, Jemth, Ann-Sofie, Almlöf, Ingrid, Font-Mateu, Jofre, Llona-Minguez, Sabin, Baranczewski, Pawel, Jeppsson, Fredrik, Homan, Evert, Almqvist, Helena, Axelsson, Hanna, Regmi, Shruti, Gustavsson, Anna-Lena, Lundbäck, Thomas, Scobie, Martin, Strömberg, Kia, Stenmark, Pål, Beato, Miguel, Helleday, Thomas

المصدر: Nature Communications ; volume 10, issue 1 ; ISSN 2041-1723

الاتاحة: https://doi.org/10.1038/s41467-019-12806-1
https://www.nature.com/articles/s41467-019-12806-1.pdf
https://www.nature.com/articles/s41467-019-12806-1

المؤلفون: Jemth, Ann-Sofie, Gustafsson, Robert, Bräutigam, Lars, Henriksson, Linda, Vallin, Karl S.A., Sarno, Antonio, Almlöf, Ingrid, Homan, Evert, Rasti, Azita, Warpman Berglund, Ulrika, Stenmark, Pål, Helleday, Thomas

المصدر: 10888-10904 ; 46 ; Nucleic Acids Research ; 20

وصف الملف: application/pdf

Relation: Nucleic Acids Research. 2018, 46 (20), 10888-10904.; urn:issn:0305-1048; http://hdl.handle.net/11250/2617646; https://doi.org/10.1093/nar/gky896; cristin:1675750

الاتاحة: http://hdl.handle.net/11250/2617646
https://doi.org/10.1093/nar/gky896

المؤلفون: Pudelko, Linda, Edwards, Steven, Balan, Mirela, Nyqvist, Daniel, Al-Saadi, Jonathan, Dittmer, Johannes, Almlöf, Ingrid, Helleday, Thomas, Bräutigam, Lars

المساهمون: Karolinska Institutes KID, Knut och Alice Wallenbergs Stiftelse, Swedish Foundation for Strategic Research, Swedish Cancer Society, Swedish Research Council, Göran Gustafsson Foundation, Swedish Children’s Cancer Foundation, Swedish Pain Relief Foundation, Torsten and Ragnar Söderberg Foundation

المصدر: Neuro-Oncology ; volume 20, issue 11, page 1475-1484 ; ISSN 1522-8517 1523-5866

الاتاحة: http://dx.doi.org/10.1093/neuonc/noy071
http://academic.oup.com/neuro-oncology/article-pdf/20/11/1475/30354022/noy071.pdf

المؤلفون: Llona-Minguez, Sabin, Höglund, Andreas, Ghassemian, Artin, Desroses, Matthieu, Calderón-Montaño, José Manuel, Burgos Morón, Estefanía, Valerie, Nicholas C. K., Wiita, Elisee, Almlöf, Ingrid, Koolmeister, Tobias, Mateus, André, Cazares-Körner, Cindy, Sanjiv, Kumar, Homan, Evert, Loseva, Olga, Baranczewski, Pawel, Darabi, Masoud, Mehdizadeh, Amir, Fayezi, Shabnam, Jemth, Ann-Sofie, Warpman Berglund, Ulrika, Sigmundsson, Kristmundur, Lundbäck, Thomas, Jenmalm Jensen, Annika, Artursson, Per, Scobie, Martin, Helleday, Thomas

المصدر: Journal of Medicinal Chemistry ; volume 60, issue 17, page 7614-7614 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.7b01137
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01137

المؤلفون: Zhang, Si Min, Desroses, Matthieu, Hagenkort, Anna, Valerie, Nicholas C. K., Rehling, Daniel, Carter, Megan, Wallner, Olov, Koolmeister, Tobias, Throup, Adam, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Lundbäck, Thomas, Axelsson, Hanna, Regmi, Shruti, Sarno, Antonio, Krämer, Andreas, Pudelko, Linda, Bräutigam, Lars, Rasti, Azita, Göttmann, Mona, Wiita, Elisée, Kutzner, Juliane, Schaller, Torsten, Kalderén, Christina, Cázares-Körner, Armando, Page, Brent D. G., Krimpenfort, Rosa, Eshtad, Saeed, Altun, Mikael, Rudd, Sean G., Knapp, Stefan, Scobie, Martin, Homan, Evert J., Warpman Berglund, Ulrika, Stenmark, Pål, Helleday, Thomas

المصدر: Nature Chemical Biology. 16(10):1120-1128

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-184407

المؤلفون: Schiedel, Matthias, Marek, Martin, Lancelot, Julien, Karaman, Berin, Almlöf, Ingrid, Schultz, Johan, Sippl, Wolfgang, Pierce, Raymond J., Romier, Christophe, Jung, Manfred

المصدر: SLAS Discovery ; volume 20, issue 1, page 112-121 ; ISSN 2472-5552

الاتاحة: http://dx.doi.org/10.1177/1087057114555307
http://journals.sagepub.com/doi/pdf/10.1177/1087057114555307
http://journals.sagepub.com/doi/full-xml/10.1177/1087057114555307
https://api.elsevier.com/content/article/PII:S2472555222071799?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2472555222071799?httpAccept=text/plain

المؤلفون: Narwal, Mohit, Jemth, Ann-Sofie, Gustafsson, Robert, Almlöf, Ingrid, Warpman Berglund, Ulrika, Helleday, Thomas, Stenmark, Pål

المصدر: Biochemistry. 57(5):593-603

مصطلحات موضوعية: MTH1, MutT, Cancer biology, NUDT1, Inhibitor, TH588, 8-oxo-dGTP, oxidative stress, hydrolase, nucleoside/nucleotide analogue, Biochemistry, biokemi

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-150682