المؤلفون: Michael D. Mandler (1939180), Andrew P. Degnan (1445947), Shasha Zhang (552910), Darpandeep Aulakh (677438), Ketleine Georges (11624098), Bhupinder Sandhu (766006), Amy Sarjeant (2230015), Yeheng Zhu (1870663), Sarah C. Traeger (1622287), Peter T. Cheng (7419323), Bruce A. Ellsworth (1870660), Alicia Regueiro-Ren (1834210)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Ecology, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, safety concerns limited, mechanical stress testing, differential scanning calorimetry, biochemical tool compounds, almost completely unknown, 5 , 3 , 135 ° c, medicinal chemistry owing, biological chemistry, versatile intermediates, valuable intermediates, single fluorine, selected azidopyridines, reported synthons, privileged nature, onset temperatures, one regioisomer, impact sensitivity, halogenated azidopyridines

Relation: https://figshare.com/articles/journal_contribution/Structural_and_Thermal_Characterization_of_Halogenated_Azidopyridines_Under-Reported_Synthons_for_Medicinal_Chemistry/16903951

الاتاحة: https://doi.org/10.1021/acs.orglett.1c03201.s001

المؤلفون: Li Xu (108702), Richard A. Hartz (2332243), Brett R. Beno (312375), Kaushik Ghosh (711838), Jinal K. Shukla (10802330), Amit Kumar (81180), Dipal Patel (10802333), Narasimharaju Kalidindi (5101184), Nadine Lemos (10037928), Shashyendra Singh Gautam (10802336), Anoop Kumar (44), Bruce A. Ellsworth (1870660), Devang Shah (20859), Harinath Sale (2866064), Dong Cheng (596943), Alicia Regueiro-Ren (1834210)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, galectin -3 inhibitors, novel tetrahydropyran-based galecti., functionalized tetrahydropyran ring, novel galectin -3 disaccharide mimics, Small-molecule galectin -3 inhibitors, Novel Tetrahydropyran-Based Thiodis., vivo evaluation, β- galactoside-binding proteins

Relation: https://figshare.com/articles/journal_contribution/Synthesis_Structure_Activity_Relationships_and_In_Vivo_Evaluation_of_Novel_Tetrahydropyran-Based_Thiodisaccharide_Mimics_as_Galectin_3_Inhibitors/14597132

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02001.s001

المؤلفون: Michael D. Mandler (1939180), Andrew P. Degnan (1445947), Shasha Zhang (552910), Darpandeep Aulakh (677438), Ketleine Georges (11624098), Bhupinder Sandhu (766006), Amy Sarjeant (2230015), Yeheng Zhu (1870663), Sarah C. Traeger (1622287), Peter T. Cheng (7419323), Bruce A. Ellsworth (1870660), Alicia Regueiro-Ren (1834210)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Ecology, Science Policy, Infectious Diseases, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, safety concerns limited, mechanical stress testing, differential scanning calorimetry, biochemical tool compounds, almost completely unknown, 5 , 3 , 135 ° c, medicinal chemistry owing, biological chemistry, versatile intermediates, valuable intermediates, single fluorine, selected azidopyridines, reported synthons, privileged nature, onset temperatures, one regioisomer, impact sensitivity, halogenated azidopyridines

Relation: https://figshare.com/articles/dataset/Structural_and_Thermal_Characterization_of_Halogenated_Azidopyridines_Under-Reported_Synthons_for_Medicinal_Chemistry/16903954

الاتاحة: https://doi.org/10.1021/acs.orglett.1c03201.s002

المؤلفون: Li Xu (108702), Richard A. Hartz (2332243), Brett R. Beno (312375), Kaushik Ghosh (711838), Jinal K. Shukla (10802330), Amit Kumar (81180), Dipal Patel (10802333), Narasimharaju Kalidindi (5101184), Nadine Lemos (10037928), Shashyendra Singh Gautam (10802336), Anoop Kumar (44), Bruce A. Ellsworth (1870660), Devang Shah (20859), Harinath Sale (2866064), Dong Cheng (596943), Alicia Regueiro-Ren (1834210)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, galectin -3 inhibitors, novel tetrahydropyran-based galecti., functionalized tetrahydropyran ring, novel galectin -3 disaccharide mimics, Small-molecule galectin -3 inhibitors, Novel Tetrahydropyran-Based Thiodis., vivo evaluation, β- galactoside-binding proteins

Relation: https://figshare.com/articles/dataset/Synthesis_Structure_Activity_Relationships_and_In_Vivo_Evaluation_of_Novel_Tetrahydropyran-Based_Thiodisaccharide_Mimics_as_Galectin_3_Inhibitors/14597135

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02001.s002