المؤلفون: Vera M. S. Isca, Gabrielle Bangay, Salvatore Princiotto, Lucília Saraíva, Daniel J. V. A. dos Santos, Alfonso T. García-Sosa, Patrícia Rijo

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/bb2ce814416a4a93a98fc9bfbad18360

المؤلفون: Maria Cristina De Rosa, Rituraj Purohit, Alfonso T. García-Sosa

المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/c6c1af3df42345dc8810b9b839894010

المؤلفون: Tereza Hofmanova, Carolina Marques, Alfonso T. García-Sosa, Óscar López, Luisa Leitzbach, Elisabete P. Carreiro, Aday González-Bakker, Adrián Puerta, Holger Stark, José M. Padrón, José G. Fernández-Bolaños, Anthony J. Burke

المصدر: Results in Chemistry, Vol 6, Iss , Pp 101032- (2023)

مصطلحات موضوعية: Oxindole, Alzheimer’s disease, Cholinesterase, Mono-amine oxidase, Molecular docking, STD-NMR, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715623002710; https://doaj.org/toc/2211-7156

URL الوصول: https://doaj.org/article/75d359ef21d247a498f7e6bdb867b7b7

المؤلفون: José Peña-Guerrero, Celia Fernández-Rubio, Alfonso T. García-Sosa, Paul A. Nguewa

المصدر: Pharmaceutics, Vol 15, Iss 7, p 1839 (2023)

مصطلحات موضوعية: BRCT, infection, disease, cancer, leishmania, therapeutic target, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/7/1839; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/dfa1bf99ac2d44aca464f35e3a1b5701

المؤلفون: Petko Alov, Merilin Al Sharif, Denitsa Aluani, Konstantin Chegaev, Jelena Dinic, Aleksandra Divac Rankov, Miguel X. Fernandes, Fabio Fusi, Alfonso T. García-Sosa, Risto Juvonen, Magdalena Kondeva-Burdina, José M. Padrón, Ilza Pajeva, Tania Pencheva, Adrián Puerta, Hannu Raunio, Chiara Riganti, Ivanka Tsakovska, Virginia Tzankova, Yordan Yordanov, Simona Saponara

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: cytochrome P450, doxorubicin, hepatotoxicity, hERG, in silico profiling, off-targets, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.831791/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/1c7deddbd8504d1eb6e324f730103fb1

المؤلفون: Larisa Ivanova, Jaana Tammiku-Taul, Alfonso T. García-Sosa, Yulia Sidorova, Mart Saarma, Mati Karelson

المصدر: ACS Omega, Vol 3, Iss 9, Pp 11407-11414 (2018)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2470-1343

URL الوصول: https://doaj.org/article/3df9a70d688b422883f8c8149382ba0d

المؤلفون: Filipe G. A. Estrada, Silvia Miccoli, Natália Aniceto, Alfonso T. García-Sosa, Rita C. Guedes

المصدر: Molecules, Vol 26, Iss 18, p 5574 (2021)

مصطلحات موضوعية: multiple myeloma, polypharmacology, multitargeting (advantages), EZH2, Proteasome 20S, molecular docking, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/18/5574; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/13709d1ff0554bb3b7d09dac5d44baf7

المؤلفون: Alfonso T. García-Sosa

المصدر: Molecules, Vol 26, Iss 5, p 1285 (2021)

مصطلحات موضوعية: machine learning, artificial intelligence, androgen receptor, random forest, deep neural network, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/5/1285; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/7f5d3f1684f84075a76587006bd3c1cb

المؤلفون: Michael Gütschow, Jean Jacques Vanden Eynde, Josef Jampilek, CongBao Kang, Arduino A. Mangoni, Paola Fossa, Rafik Karaman, Andrea Trabocchi, Peter J. H. Scott, Jóhannes Reynisson, Simona Rapposelli, Stefania Galdiero, Jean-Yves Winum, Chiara Brullo, Katalin Prokai-Tatrai, Arun K. Sharma, Matthieu Schapira, Yasu-Taka Azuma, Laura Cerchia, Mariana Spetea, Giangiacomo Torri, Simona Collina, Athina Geronikaki, Alfonso T. García-Sosa, M. Helena Vasconcelos, Maria Emília Sousa, Ivan Kosalec, Tiziano Tuccinardi, Iola F. Duarte, Jorge A. R. Salvador, Massimo Bertinaria, Maurizio Pellecchia, Jussara Amato, Giulio Rastelli, Paula A. C. Gomes, Rita C. Guedes, Jean-Marc Sabatier, Ana Estévez-Braun, Bruno Pagano, Stefano Mangani, Rino Ragno, George Kokotos, Margherita Brindisi, Florenci V. González, Fernanda Borges, Mariarosaria Miloso, Jarkko Rautio, Diego Muñoz-Torrero

المصدر: Molecules, Vol 25, Iss 13, p 2968 (2020)

مصطلحات موضوعية: n/a, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/13/2968; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/d1b45d5624194ce7bc35f0b2a26b0ee6

المؤلفون: Stefano Alcaro, Maria Laura Bolognesi, Alfonso T. García-Sosa, Simona Rapposelli

المصدر: Frontiers in Chemistry, Vol 7 (2019)

مصطلحات موضوعية: multi-target paradigms, multi-target molecules, multidisciplinary cooperation, drug discovery, chemotheca, compliance, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fchem.2019.00071/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/60390c30da8b4c8f971896b98243d973

المؤلفون: Hana Elshaflu, Tamara R. Todorović, Milan Nikolić, Aleksandar Lolić, Aleksandar Višnjevac, Stefanie Hagenow, José M. Padrón, Alfonso T. García-Sosa, Ivana S. Djordjević, Sonja Grubišić, Holger Stark, Nenad R. Filipović

المصدر: Frontiers in Chemistry, Vol 6 (2018)

مصطلحات موضوعية: selenazoles, MAO B, Anticancer activity, Docking, Antioxidant agents, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fchem.2018.00247/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/6143e71dc37a44abaa9cad09b0e2d274

المؤلفون: Abraham Yosipof, Rita C. Guedes, Alfonso T. García-Sosa

المصدر: Frontiers in Chemistry, Vol 6 (2018)

مصطلحات موضوعية: machine-learning, drug, data-mining, logistic, organ, drug design, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fchem.2018.00162/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/b7aef9ae6a694e588879a424258f5cf3

المؤلفون: Bart I. Roman, Rita C. Guedes, Christian V. Stevens, Alfonso T. García-Sosa

المصدر: Frontiers in Chemistry, Vol 6 (2018)

مصطلحات موضوعية: blebbistatin, fingerprint, ECFP, multitarget, antitarget, myosin II, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fchem.2018.00179/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/998163fdb7f7460d8ebabe15dc9c9980

المؤلفون: Jean Jacques Vanden Eynde, Arduino A. Mangoni, Jarkko Rautio, Jérôme Leprince, Yasu-Taka Azuma, Alfonso T. García-Sosa, Christopher Hulme, Josef Jampilek, Rafik Karaman, Wei Li, Paula A. C. Gomes, Dimitra Hadjipavlou-Litina, Raffaele Capasso, Athina Geronikaki, Laura Cerchia, Jean-Marc Sabatier, Rino Ragno, Tiziano Tuccinardi, Andrea Trabocchi, Jean-Yves Winum, F. Javier Luque, Katalin Prokai-Tatrai, Mariana Spetea, Michael Gütschow, Ivan Kosalec, Catherine Guillou, M. Helena Vasconcelos, George Kokotos, Giulio Rastelli, Maria Emília de Sousa, Clementina Manera, Sandra Gemma, Stefano Mangani, Carlo Siciliano, Stefania Galdiero, Hong Liu, Peter J. H. Scott, Cristóbal de los Ríos, Luigi A. Agrofoglio, Simona Collina, Rita C. Guedes, Diego Muñoz-Torrero

المصدر: Molecules, Vol 25, Iss 1, p 119 (2019)

مصطلحات موضوعية: n/a, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/1/119; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/3cd6ccb2d2144bde8974e0647ecc5397

المؤلفون: Andrés Vacas, Celia Fernández-Rubio, Miriam Algarabel, José Peña-Guerrero, Esther Larrea, Fabio Rocha Formiga, Alfonso T. García-Sosa, Paul A. Nguewa

المصدر: Biomolecules, Vol 9, Iss 11, p 723 (2019)

مصطلحات موضوعية: leishmania, ntd, docking, molecular dynamics, drug resistance, paromomycin, kinase, treatment, lmjf.22.0810, lmjean3, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-273X/9/11/723; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/f715d9bcc4a547f3848352428924f995

المؤلفون: Strahinja Stevanovic, Milan Sencanski, Mathieu Danel, Christophe Menendez, Roumaissa Belguedj, Abdelmalek Bouraiou, Katarina Nikolic, Sandrine Cojean, Philippe M. Loiseau, Sanja Glisic, Michel Baltas, Alfonso T. García-Sosa

المصدر: Molecules, Vol 24, Iss 7, p 1282 (2019)

مصطلحات موضوعية: Leishmania, arginase, in silico, anti-target, in vitro, anti-leishmanial inhibitors, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/7/1282; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/df39e0b494e14ea1ae0280a0c717ab36

المؤلفون: Anabela Borges, Manuel Simões, Tamara R. Todorović, Nenad R. Filipović, Alfonso T. García-Sosa

المصدر: Molecules, Vol 23, Iss 6, p 1385 (2018)

مصطلحات موضوعية: antibacterial resistance, antivirulence/antipathogenic compounds, biofilm prevention, cobalt complex, furvina, pyocyanin, pyoverdine, quorum sensing inhibition, transcriptional activator protein LasR, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/23/6/1385; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/9396d72fd01a4c48afd4acbaef253abc

المؤلفون: Sanja Glisic, Milan Sencanski, Vladimir Perovic, Strahinja Stevanovic, Alfonso T. García-Sosa

المصدر: Molecules, Vol 21, Iss 5, p 589 (2016)

مصطلحات موضوعية: Leishmania, arginase, flavonoid, in silico, screen, anti-target, leishmaniasis, natural products, pregnane-X-receptor, sulfotransferase, cytochrome P450, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/21/5/589; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/82dfdeb56a3e4e9286549002fe414cc5

المؤلفون: Carlos M. Gastalho, Ana M. Sena, Óscar López, José G. Fernández-Bolaños, Alfonso T. García-Sosa, Florbela Pereira, Célia M. Antunes, Ana R. Costa, Anthony J. Burke, Elisabete P. Carreiro

المصدر: International Journal of Molecular Sciences ; Volume 25 ; Issue 20 ; Pages: 11153

مصطلحات موضوعية: 1,2,3-triazole, dihydropyrimidinone, antioxidant activity, cholinesterases, STD-NMR, docking

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms252011153

الاتاحة: https://doi.org/10.3390/ijms252011153

المؤلفون: Alfonso T. García-Sosa, Uko Maran

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 13; Pages: 6695

مصطلحات موضوعية: androgen receptor, bayesian, multivariate logistic regression, chemical fingerprints, ecfp, docking, toxicity, human, chimp, rat

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Informatics; https://dx.doi.org/10.3390/ijms22136695

الاتاحة: https://doi.org/10.3390/ijms22136695