المؤلفون: Chen, Fuhui, Gurler, Sevim B., Novo, David, Selli, Cigdem, Alferez, Denis G., Eroglu, Secil, Pavlou, Kyriaki, Zhang, Jingwei, Sims, Andrew H., Humphreys, Neil E., Adamson, Antony, Campbell, Andrew, Sansom, Owen J., Tournier, Cathy, Clarke, Robert B., Brennan, Keith, Streuli, Charles H., Ucar, Ahmet

المصدر: Chen , F , Gurler , S B , Novo , D , Selli , C , Alferez , D G , Eroglu , S , Pavlou , K , Zhang , J , Sims , A H , Humphreys , N E , Adamson , A , Campbell , A , Sansom , O J , Tournier , C , Clarke , R B , Brennan , K , Streuli , C H & Ucar , A 2023 , ' RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells ' , ....

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/dfe3a6b0-0886-4a43-b5bf-a3eb50e35b83
https://doi.org/10.1038/s41388-022-02574-6
http://www.scopus.com/inward/record.url?scp=85145572631&partnerID=8YFLogxK

المؤلفون: Simões, Bruno M, O'Brien, Ciara S, Eyre, Rachel, Silva, Andreia, Yu, Ling, Sarmiento-Castro, Aida, Alférez, Denis G, Spence, Kath, Santiago-Gómez, Angélica, Chemi, Francesca, Acar, Ahmet, Gandhi, Ashu, Howell, Anthony, Brennan, Keith, Rydén, Lisa, Catalano, Stefania, Andó, Sebastiano, Gee, Julia, Ucar, Ahmet, Sims, Andrew H, Marangoni, Elisabetta, Farnie, Gillian, Landberg, Göran, Howell, Sacha J, Clarke, Robert B

المصدر: Cell Reports BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation. 12(12):1968-1977

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology

وصف الملف: electronic

URL الوصول: https://lup.lub.lu.se/record/8035804
https://portal.research.lu.se/files/3779460/8852005.pdf
http://www.ncbi.nlm.nih.gov/pubmed/26387946?dopt=Abstract
http://dx.doi.org/10.1016/j.celrep.2015.08.050

المؤلفون: Eyre, Rachel, Alférez, Denis G., Santiago-Gómez, Angélica, Spence, Kath, McConnell, James C., Hart, Claire, Simões, Bruno M., Lefley, Diane, Tulotta, Claudia, Storer, Joanna, Gurney, Austin, Clarke, Noel, Brown, Mick, Howell, Sacha J., Sims, Andrew H., Farnie, Gillian, Ottewell, Penelope D., Clarke, Robert B.

المساهمون: Breast Cancer Now, RCUK | Medical Research Council

المصدر: Nature Communications ; volume 10, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-019-12807-0
https://www.nature.com/articles/s41467-019-12807-0.pdf
https://www.nature.com/articles/s41467-019-12807-0

المؤلفون: Alferez, Denis G., Simões, Bruno M., Howell, Sacha J., Clarke, Robert B.

المساهمون: University of Manchester

المصدر: Current Stem Cell Reports ; volume 4, issue 1, page 81-94 ; ISSN 2198-7866

الاتاحة: http://dx.doi.org/10.1007/s40778-018-0114-z
http://link.springer.com/article/10.1007/s40778-018-0114-z/fulltext.html
http://link.springer.com/content/pdf/10.1007/s40778-018-0114-z.pdf

المؤلفون: Byrne, Annette T., Alferez, Denis G., Amant, Frederic, Annibali, Daniela, Arribas, Joaquin, Biankin, Andrew V., Bruna, Alejandra, Budinska, Eva, Caldas, Carlos, Chang, David K., Clarke, Robert B., Clevers, Hans, Coukos, George, Dangles-Marie, Virginie, Eckhardt, S. Gail, Gonzalez-Suarez, Eva, Hermans, Els, Hidalgo, Manuel, Jarzabek, Monika A., de Jong, Steven, Jonkers, Jos, Kemper, Kristel, Lanfrancone, Luisa, Maelandsmo, Gunhild Mari, Marangoni, Elisabetta, Marine, Jean-Christophe, Medico, Enzo, Norum, Jens Henrik, Palmer, Hector G., Peeper, Daniel S., Pelicci, Pier Giuseppe, Piris-Gimenez, Alejandro, Roman-Roman, Sergio, Rueda, Oscar M., Seoane, Joan, Serra, Violeta, Soucek, Laura, Vanhecke, Dominique, Villanueva, Alberto, Vinolo, Emilie, Bertotti, Andrea, Trusolino, Livio

المصدر: Byrne , A T , Alferez , D G , Amant , F , Annibali , D , Arribas , J , Biankin , A V , Bruna , A , Budinska , E , Caldas , C , Chang , D K , Clarke , R B , Clevers , H , Coukos , G , Dangles-Marie , V , Eckhardt , S G , Gonzalez-Suarez , E , Hermans , E , Hidalgo , M , Jarzabek , M A , de Jong , S , Jonkers , J , Kemper , K , Lanfrancone , L ....

مصطلحات موضوعية: CIRCULATING TUMOR-CELLS, METASTATIC COLORECTAL-CANCER, NEGATIVE BREAST CANCERS, HEMATOPOIETIC STEM-CELLS, DUCTAL PANCREATIC-CANCER, ACQUIRED-RESISTANCE, IN-VIVO, GENE-EXPRESSION, LUNG-CANCER, MOUSE MODEL

الاتاحة: https://hdl.handle.net/11370/1926291e-097e-4963-91ce-48792115d474
https://research.rug.nl/en/publications/1926291e-097e-4963-91ce-48792115d474
https://doi.org/10.1038/nrc.2016.140
http://diposit.ub.edu/dspace/bitstream/2445/123494/1/Byrne_et_al_NRC_2018.pdf

المؤلفون: Byrne, Annette T, Alférez, Denis G, Amant, Frédéric, Annibali, Daniela, Arribas, Joaquín, Biankin, Andrew V, Bruna, Alejandra, Budinská, Eva, Caldas, Carlos, Chang, David K, Clarke, Robert B, Clevers, Hans, Coukos, George, Dangles-Marie, Virginie, Eckhardt, S Gail, Gonzalez-Suarez, Eva, Hermans, Els, Hidalgo, Manuel, Jarzabek, Monika A, de Jong, Steven, Jonkers, Jos, Kemper, Kristel, Lanfrancone, Luisa, Mælandsmo, Gunhild Mari, Marangoni, Elisabetta, Marine, Jean-Christophe, Medico, Enzo, Norum, Jens Henrik, Palmer, Héctor G, Peeper, Daniel S, Pelicci, Pier Giuseppe, Piris-Gimenez, Alejandro, Roman-Roman, Sergio, Rueda, Oscar M, Seoane, Joan, Serra, Violeta, Soucek, Laura, Vanhecke, Dominique, Villanueva, Alberto, Vinolo, Emilie, Bertotti, Andrea, Trusolino, Livio

المصدر: Byrne , A T , Alférez , D G , Amant , F , Annibali , D , Arribas , J , Biankin , A V , Bruna , A , Budinská , E , Caldas , C , Chang , D K , Clarke , R B , Clevers , H , Coukos , G , Dangles-Marie , V , Eckhardt , S G , Gonzalez-Suarez , E , Hermans , E , Hidalgo , M , Jarzabek , M A , de Jong , S , Jonkers , J , Kemper , K , Lanfrancone , L ....

مصطلحات موضوعية: Published Erratum

Relation: https://pure.knaw.nl/portal/en/publications/60b166f8-27e4-4c66-bfba-b5b24a0d2610

الاتاحة: https://pure.knaw.nl/portal/en/publications/60b166f8-27e4-4c66-bfba-b5b24a0d2610
https://doi.org/10.1038/nrc.2017.85
https://hdl.handle.net/20.500.11755/60b166f8-27e4-4c66-bfba-b5b24a0d2610

المؤلفون: Eyre, Rachel, Alférez, Denis G, Spence, Katherine, Kamal, Mohamed, Shaw, Frances L, Simões, Bruno M, Santiago-Gómez, Angélica, Sarmiento-Castro, Aida, Bramley, Maria, Absar, Mohammed, Saad, Zahida, Chatterjee, Sumohan, Kirwan, Cliona, Gandhi, Ashu, Armstrong, Anne C, Wardley, Andrew M, O'Brien, Ciara S, Farnie, Gillian, Howell, Sacha J, Clarke, Robert B

المصدر: Eyre , R , Alférez , D G , Spence , K , Kamal , M , Shaw , F L , Simões , B M , Santiago-Gómez , A , Sarmiento-Castro , A , Bramley , M , Absar , M , Saad , Z , Chatterjee , S , Kirwan , C , Gandhi , A , Armstrong , A C , Wardley , A M , O'Brien , C S , Farnie , G , Howell , S J & Clarke , R B 2016 , ' Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression ....

الاتاحة: https://research.manchester.ac.uk/en/publications/0e6dba5e-e368-4422-84ba-63eea0e79dff
https://doi.org/10.1007/s10911-016-9361-8

المؤلفون: Dobrolecki, Lacey E., Airhart, Susie D., Alférez, Denis G., Aparicio, Samuel, Behbod, Fariba, Bentires-Alj, Mohamed, Brisken, Cathrin, Bult, Carol J., Cai, Shirong, Clarke, Robert B., Dowst, Heidi, Ellis, Matthew J., González Suárez, Eva, Iggo, Richard D., Kabos, Peter, Li, Shunqiang, Lindeman, Geoffrey J., Marangoni, Elisabetta, McCoy, Aaron, Meric-Bernstam, Funda, Piwnica-Worms, Helena, Poupon, Marie-France, Reis-Filho, Jorge, Sartorius, Carol A., Scabia, Valentina, Sflomos, George, Tu, Yizheng, Vaillant, François, Visvader, Jane E., Welm, Alana, Wicha, Max S., Lewis, Michael T.

المصدر: Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

مصطلحات موضوعية: Càncer de mama, Breast cancer

وصف الملف: 46 p.; application/pdf

Relation: Versió postprint del document publicat a: https://doi.org/10.1007/s10555-016-9653-x; Cancer and Metastasis Reviews, 2016, vol. 35, num. 4, p. 547-573; https://doi.org/10.1007/s10555-016-9653-x; http://hdl.handle.net/2445/125356

الاتاحة: http://hdl.handle.net/2445/125356

المؤلفون: Simões, Bruno M, Alferez, Denis G, Howell, Sacha J, Clarke, Robert B

المصدر: Endocrine-Related Cancer ; volume 22, issue 6, page T177-T186 ; ISSN 1351-0088 1479-6821

الاتاحة: http://dx.doi.org/10.1530/erc-15-0350
https://erc.bioscientifica.com/view/journals/erc/22/6/T177.xml
https://erc.bioscientifica.com/downloadpdf/journals/erc/22/6/T177.xml

المؤلفون: Simoes, Bruno M, Santiago-Gómez, Angélica, Chiodo, Chiara, Moreira, Tiago, Conole, D., Lovell, S., Alférez, Denis G, Eyre, Rachel, Spence, Katherine, Sarmiento-Castro, Aida, Kohler, Bertram, Morisset, L., Lanzino, M., Ando, S., Marangoni, E., Sims, A. H., Tate, E. W., Howell, Sacha J, Clarke, Robert B

المساهمون: Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester

Relation: https://dx.doi.org/10.1038/s41388-020-1335-z; B. M. Simoes, A. Santiago-Gomez, C. Chiodo et al Targeting STAT3 signaling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer. Oncogene. 2020.; http://hdl.handle.net/10541/623008; Oncogene

الاتاحة: http://hdl.handle.net/10541/623008
https://doi.org/10.1038/s41388-020-1335-z

المؤلفون: Lefley, D, Howard, F, Arshad, F, Bradbury, S, Brown, H, Tulotta, C, Eyre, Rachel, Alférez, Denis G, Wilkinson, JM, Holen, I, Clarke, Robert B, Ottewell, P

المساهمون: Department of Oncology and Metabolism, Mellanby Centre for Bone Research, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX

Relation: https://dx.doi.org/10.1186/s13058-019-1220-2; Lefley D, Howard F, Arshad F, Bradbury S, Brown H, Tulotta C, et al. Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts. Breast Cancer Res. 2019;21(1):130.; http://hdl.handle.net/10541/622679; Breast cancer research

الاتاحة: http://hdl.handle.net/10541/622679
https://doi.org/10.1186/s13058-019-1220-2

المؤلفون: Howell, Sacha J, Simoes, Bruno M, Alférez, Denis G, Eyre, Rachel, Spence, Katherine, Santiago-Gómez, Angélica, Sarmiento-Castro, Aida, Tanaka, I, Howat, D, Clarke, Robert B

المساهمون: University of Manchester, The Christie NHS Foundation Trust

Relation: SFX-01 targets Wnt signalling to inhibit stem-like cells in breast cancer patient-derived xenograft tumours 2017, 77 (4 Supplement):PD2-02 Cancer Research; http://hdl.handle.net/10541/620349; Cancer Research

الاتاحة: http://hdl.handle.net/10541/620349
https://doi.org/10.1158/1538-7445.SABCS16-PD2-02

المؤلفون: Dobrolecki, Lacey E., Airhart, Susie D., Alferez, Denis G., Aparicio, Samuel, Behbod, Fariba, Bentires-Alj, Mohamed, Brisken, Cathrin, Bult, Carol J., Cai, Shirong, Clarke, Robert B., Dowst, Heidi, Ellis, Matthew J., Gonzalez-Suarez, Eva, Iggo, Richard D., Kabos, Peter, Li, Shunqiang, Lindeman, Geoffrey J., Marangoni, Elisabetta, Mccoy, Aaron, Meric-Bernstam, Funda, Piwnica-Worms, Helen, Poupon, Marie-France, Reis-Filho, Jorge, Sartorius, Carol A., Scabia, Valentina, Sflomos, George, Tu, Yizheng, Vaillant, Francois, Visvader, Jane E., Welm, Alana, Wicha, Max S., Lewis, Michael T.

المصدر: http://infoscience.epfl.ch/record/225901.

Relation: http://infoscience.epfl.ch/record/225901; ISI:000391928200005; https://infoscience.epfl.ch/record/225901/files/art3A10.10072Fs10555-016-9653-x.pdf

الاتاحة: http://infoscience.epfl.ch/record/225901
https://doi.org/10.1007/s10555-016-9653-x
https://infoscience.epfl.ch/record/225901/files/art3A10.10072Fs10555-016-9653-x.pdf

المؤلفون: Dobrolecki, Lacey E, Airhart, Susan D, Alferez, Denis G, Aparicio, Samuel, Behbod, Fariba, Bentires-Alj, Mohamed, Brisken, Cathrin, Bult, Carol J, Cai, Shirong, Clarke, Robert B, Dowst, Heidi, Ellis, Matthew J, Gonzalez-Suarez, Eva, Iggo, Richard D, Kabos, Peter, Li, Shunqiang, Lindeman, Geoffrey J, Marangoni, Elisabetta, McCoy, Aaron, Meric-Bernstam, Funda, Piwnica-Worms, Helen, Poupon, Marie-France, Reis-Filho, Jorge, Sartorius, Carol A, Scabia, Valentina, Sflomos, George, Tu, Yizheng, Vaillant, François, Visvader, Jane E, Welm, Alana, Wicha, Max S, Lewis, Michael T

المصدر: Faculty Research 2016

مصطلحات موضوعية: Life Sciences, Medicine and Health Sciences

Relation: https://mouseion.jax.org/stfb2016/259

الاتاحة: https://mouseion.jax.org/stfb2016/259

المؤلفون: Eyre, Rachel, Alférez, Denis G, Spence, Katherine, Kamal, Mohamed, Shaw, Frances L, Simões, Bruno M, Santiago-Gómez, Angélica, Sarmiento-Castro, Aida, Bramley, M, Absar, M, Saad, Z, Chatterjee, S, Kirwan, C, Gandhi, A, Armstrong, Anne C, Wardley, Andrew M, O'Brien, Ciara S, Farnie, Gillian, Howell, Sacha J, Clarke, Robert B

المساهمون: Breast Biology Group, Breast Cancer Now Research Unit, Division of Molecular and Clinical Cancer Sciences, Manchester Cancer, Research Centre, University of Manchester, Wilmslow Road, Manchester, M20 4QL

Relation: Erratum to: Patient-derived mammosphere and xenograft tumour initiation correlates with progression to metastasis. 2016, J Mammary Gland Biol Neoplasia; http://hdl.handle.net/10541/620034; Journal of Mammary Gland Biology and Neoplasia

الاتاحة: http://hdl.handle.net/10541/620034
https://doi.org/10.1007/s10911-016-9364-5

المؤلفون: Byrne, Annette T, Alférez, Denis G, Amant, Frédéric, Annibali, Daniela, Arribas, Joaquín, Biankin, Andrew V, Bruna, Alejandra, Budinská, Eva, Caldas, Carlos, Chang, David K, Clarke, Robert B, Clevers, Hans, Coukos, George, Dangles-Marie, Virginie, Eckhardt, S Gail, Gonzalez-Suarez, Eva, Hermans, Els, Hidalgo, Manuel, Jarzabek, Monika A, de Jong, Steven, Jonkers, Jos, Kemper, Kristel, Lanfrancone, Luisa, Mælandsmo, Gunhild Mari, Marangoni, Elisabetta, Marine, Jean-Christophe, Medico, Enzo, Norum, Jens Henrik, Palmer, Héctor G, Peeper, Daniel S, Pelicci, Pier Giuseppe, Piris-Gimenez, Alejandro, Roman-Roman, Sergio, Rueda, Oscar M, Seoane, Joan, Serra, Violeta, Soucek, Laura, Vanhecke, Dominique, Villanueva, Alberto, Vinolo, Emilie, Bertotti, Andrea, Trusolino, Livio

المصدر: Nature reviews. Cancer vol.17 (2017) nr.4 p.254-268 [ISSN 1474-175X]

مصطلحات الفهرس: Animals, Biomarkers, Tumor, Clinical Trials as Topic, Disease Models, Animal, Drug Resistance, Neoplasm, Humans, Immunotherapy, Mice, Neoplasm Metastasis, Neoplasms, Neoplastic Stem Cells, Precision Medicine, Xenograft Model Antitumor Assays, Journal Article, Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural, Artikel, Article

URL: https://pure.knaw.nl/portal/en/publications/16bfb9b5-9f02-4c6b-9b53-81bc13ff3bf7

المؤلفون: CMM Sectie Molecular Cancer Research, Hubrecht Institute with UMC, Cancer, Regenerative Medicine and Stem Cells, Child Health, Byrne, Annette T., Alférez, Denis G., Amant, Frédéric, Annibali, Daniela, Arribas, Joaquín, Biankin, Andrew V., Bruna, Alejandra, Budinská, Eva, Caldas, Carlos, Chang, David K., Clarke, Robert B., Clevers, Hans, Coukos, George, Dangles-Marie, Virginie, Gail Eckhardt, S., Gonzalez-Suarez, Eva, Hermans, Els, Hidalgo, Manuel, Jarzabek, Monika A., De Jong, Steven, Jonkers, Jos, Kemper, Kristel, Lanfrancone, Luisa, Mælandsmo, Gunhild Mari, Marangoni, Elisabetta, Marine, Jean Christophe, Medico, Enzo, Norum, Jens Henrik, Palmer, Héctor G., Peeper, Daniel S., Pelicci, Pier Giuseppe, Piris-Gimenez, Alejandro, Roman-Roman, Sergio, Rueda, Oscar M., Seoane, Joan, Serra, Violeta, Soucek, Laura, Vanhecke, Dominique, Villanueva, Alberto, Vinolo, Emilie, Bertotti, Andrea, Trusolino, Livio

URL: https://doi.org/10.1038/nrc.2016.140
http://hdl.handle.net/1874/349623
https://dspace.library.uu.nl/handle/1874/349623
http://www.scopus.com/inward/record.url?scp=85009959524&partnerID=8YFLogxK
1474-175X
Nature Reviews Cancer
17
4
254
268

المؤلفون: Alferez, Denis G, Goodlad, Robert A, Odedra, Rajesh, Sini, Patrizia, Crafter, Claire, Ryan, Anderson J, Wedge, Stephen R, Wright, Nicholas A, Anderson, Elizabeth, Wilkinson, Robert W

المصدر: Alferez , D G , Goodlad , R A , Odedra , R , Sini , P , Crafter , C , Ryan , A J , Wedge , S R , Wright , N A , Anderson , E & Wilkinson , R W 2012 , ' Inhibition of Aurora-B kinase activity confers antitumor efficacy in preclinical mouse models of early and advanced gastrointestinal neoplasia ' , International Journal of Oncology , vol. 41 , no. 4 , pp. 1475-85 . https://doi.org/10.3892/ijo.2012.1580

مصطلحات موضوعية: Animals, Aurora Kinase B, Cell Proliferation, Colorectal Neoplasms, Gastrointestinal Neoplasms, Gene Expression Regulation, Neoplastic, HCT116 Cells, Histones, Humans, Mice, Phosphorylation, Quinazolines, Xenograft Model Antitumor Assays, Journal Article, Research Support, Non-U.S. Gov't, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

Relation: https://research.manchester.ac.uk/en/publications/1211347e-fbbb-4b47-88ed-6cb43e0403b1

الاتاحة: https://research.manchester.ac.uk/en/publications/1211347e-fbbb-4b47-88ed-6cb43e0403b1
https://doi.org/10.3892/ijo.2012.1580

المؤلفون: Alferez, Denis G, Ryan, Anderson J, Goodlad, Robert A, Wright, Nick A, Wilkinson, Robert W

المصدر: Alferez , D G , Ryan , A J , Goodlad , R A , Wright , N A & Wilkinson , R W 2010 , ' Effects of vandetanib on adenoma formation in a dextran sodium sulphate enhanced Apc(MIN/+) mouse model ' , International Journal of Oncology , vol. 37 , no. 4 , pp. 767-72 .

مصطلحات موضوعية: Adenoma, Animals, Antineoplastic Agents, Colitis, Colonic Neoplasms, Dextran Sulfate, Disease Models, Animal, Genes, APC, Intestine, Small, Mice, Inbred C57BL, Piperidines, Protein Kinase Inhibitors, Quinazolines, Receptor, Epidermal Growth Factor, Vascular Endothelial Growth Factor Receptor-2, beta Catenin, Journal Article, Research Support, Non-U.S. Gov't, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/a99ed89a-c03f-46cc-82d0-4e89c285ae8e