المؤلفون: Alexandra J. Machen, Mark T. Fisher, Bret D. Freudenthal

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/3f8e058c49e347208faec432f78c2113

المؤلفون: Pierce T. O'Neil, Alexandra J. Machen, Benjamin C. Deatherage, Caleb Trecazzi, Alexander Tischer, Venkata R. Machha, Matthew T. Auton, Michael R. Baldwin, Tommi A. White, Mark T. Fisher

المصدر: Frontiers in Molecular Biosciences, Vol 5 (2018)

مصطلحات موضوعية: chaperonin GroEL, electron microscopy, tilt series, tetanus neurotoxin, anthrax toxin, von Willebrand Factor, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fmolb.2018.00046/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/a870c8a57acf4a8c80dd837c14933afb

المؤلفون: Alexandra J. Machen, Narahari Akkaladevi, Caleb Trecazzi, Pierce T. O’Neil, Srayanta Mukherjee, Yifei Qi, Rebecca Dillard, Wonpil Im, Edward P. Gogol, Tommi A. White, Mark T. Fisher

المصدر: Toxins, Vol 9, Iss 10, p 298 (2017)

مصطلحات موضوعية: anthrax toxin, lethal factor, protective antigen, pore formation, translocation, nanodisc, cryo-EM, cryoSPARC, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/9/10/298; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/fede19d32f3a48ffa74c7d3b15e73737

المؤلفون: Chamandi S. Dampalla (11068618), Harry Nhat Nguyen (9455664), Athri D. Rathnayake (4239754), Yunjeong Kim (315112), Krishani Dinali Perera (11794426), Trent K. Madden (12695813), Hayden A. Thurman (11668155), Alexandra J. Machen (3040980), Maithri M. Kashipathy (9455670), Lijun Liu (452265), Kevin P. Battaile (418240), Scott Lovell (122251), Kyeong-Ok Chang (5282), William C. Groutas (1403371)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, resolution cocrystal structures, highly pathogenic coronaviruses, broadly acting agents, inhibitors described herein, highly potent inhibitors, structural determinants associated, pro , 50 , potently inhibited mers, acting antivirals, based inhibitors, worldwide impact, virological studies, viral replication, validated target, urgent need, taken together, studies suggest

Relation: https://figshare.com/articles/journal_contribution/Broad-Spectrum_Cyclopropane-Based_Inhibitors_of_Coronavirus_3C-like_Proteases_Biochemical_Structural_and_Virological_Studies/21787150

الاتاحة: https://doi.org/10.1021/acsptsci.2c00206.s001

المؤلفون: Chamandi S. Dampalla, Harry Nhat Nguyen, Athri D. Rathnayake, Yunjeong Kim, Krishani Dinali Perera, Trent K. Madden, Hayden A. Thurman, Alexandra J. Machen, Maithri M. Kashipathy, Lijun Liu, Kevin P. Battaile, Scott Lovell, Kyeong-Ok Chang, William C. Groutas

المصدر: ACS Pharmacology & Translational Science. 6:181-194

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6dfd5a98cb044d01fc1d704fa8f0de58
https://doi.org/10.1021/acsptsci.2c00206

المؤلفون: Chamandi S. Dampalla, Matthew J. Miller, Yunjeong Kim, Alexandria Zabiegala, Harry Nhat Nguyen, Trent K. Madden, Hayden A. Thurman, Alexandra J. Machen, Anne Cooper, Lijun Liu, Kevin P. Battaile, Scott Lovell, Kyeong-Ok Chang, William C. Groutas

المصدر: European Journal of Medicinal Chemistry. 254:115376

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3a75b9580fac49a9aab4eb1d9fc74881
https://doi.org/10.1016/j.ejmech.2023.115376

المؤلفون: Alexandra J Machen, Mark T. Fisher, Wendy A. Lea, Karen R. Khar, Matthew Auton, Alexander Tischer, Pierce T. O’Neil, Subhashchandra Naik, Tapan Chaudhri, Wesley Mcginn-Straub, John Karanicolas, Joshua R. Burns, Michael R. Baldwin

المصدر: Biochemistry. 55:4885-4908

مصطلحات موضوعية: 0301 basic medicine, Protein Denaturation, Protein Folding, 030102 biochemistry & molecular biology, Proteins, Biosensing Techniques, Chaperonin 60, Protein aggregation, Ligands, Ligand (biochemistry), Biochemistry, GroEL, Article, Chaperonin, Kinetics, 03 medical and health sciences, chemistry.chemical_compound, Crystallography, 030104 developmental biology, Monomer, chemistry, Thermodynamics, Denaturation (biochemistry), Protein folding, Target protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96424c6b9eef2d3519b3cee8899fe9ed
https://doi.org/10.1021/acs.biochem.6b00293

المؤلفون: Mark T. Fisher, Alexandra J Machen, John Karanicolas, Quyen Q. Hoang, Wei Wang, Michael R. Baldwin, Karen R. Khar, Jackie A. Thompson, Pierce T. O’Neil

المصدر: Methods in Molecular Biology ISBN: 9781493988198

مصطلحات موضوعية: Data Analysis, Protein Denaturation, Protein Folding, 0303 health sciences, Chemistry, 030302 biochemistry & molecular biology, Temperature, Proteins, Biosensing Techniques, GroEL, Article, Cell Line, Chaperonin, Kinetics, Protein Aggregates, User-Computer Interface, 03 medical and health sciences, Biophysics, Protein folding, Immobilized proteins, Denaturation (biochemistry), Software, Protein Binding, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a33d0f641464e3ab5855db3f1528bde
https://doi.org/10.1007/978-1-4939-8820-4_19

المؤلفون: Bradley L. Pentelute, Alexandra J Machen, Mark T. Fisher, Pierce T. O’Neil, Maria T. Villar, Antonio Artigues

المساهمون: Massachusetts Institute of Technology. Department of Chemistry

المصدر: Journal of Visualized Experiments (JOVE)

مصطلحات موضوعية: 0301 basic medicine, Antigens, Bacterial, General Immunology and Microbiology, Chemistry, Anthrax toxin, General Chemical Engineering, General Neuroscience, Bacterial Toxins, Biosensing Techniques, Mass spectrometry, Mass Spectrometry, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Microscopy, Electron, 030104 developmental biology, Membrane, Interferometry, Biophysics, Ternary complex, Biosensor, Late endosome, Binding selectivity, Cysteine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b4cfa3b43b0b8417f70f6902dc3aa5
https://doi.org/10.3791/57902-v

المؤلفون: Edward P. Gogol, Alexandra J Machen, Yifei Qi, Srayanta Mukherjee, Tommi A. White, Rebecca Dillard, Caleb Trecazzi, Wonpil Im, Pierce T. O’Neil, Narahari Akkaladevi, Mark T. Fisher

المصدر: Toxins, Vol 9, Iss 10, p 298 (2017)
Toxins
Toxins; Volume 9; Issue 10; Pages: 298

مصطلحات موضوعية: 0301 basic medicine, Cryo-electron microscopy, cryoSPARC, Health, Toxicology and Mutagenesis, Anthrax toxin, Bacterial Toxins, translocation, lcsh:Medicine, Molecular Dynamics Simulation, Biology, Toxicology, anthrax toxin, lethal factor, protective antigen, pore formation, nanodisc, cryo-EM, Article, Anthrax, 03 medical and health sciences, Lethal toxin, Nanodisc, Antigens, Bacterial, 030102 biochemistry & molecular biology, Cryoelectron Microscopy, lcsh:R, Protein Structure, Tertiary, Lethal factor, Crystallography, 030104 developmental biology, Protective antigen, Solubilization, Biophysics, Anthrax toxin protective antigen

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0dda37b6ac697553b1451c0e848dcba
https://www.mdpi.com/2072-6651/9/10/298

المؤلفون: Pierce T. O'Neil, Alexandra J. Machen, Benjamin C. Deatherage, Caleb Trecazzi, Alexander Tischer, Venkata R. Machha, Matthew T. Auton, Michael R. Baldwin, Tommi A. White, Mark T. Fisher

مصطلحات موضوعية: Biochemistry, Molecular Biology, Structural Biology, Enzymes, Protein Trafficking, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Receptors and Membrane Biology, Signal Transduction, Structural Biology (incl. Macromolecular Modelling), Synthetic Biology, chaperonin GroEL, electron microscopy, tilt series, tetanus neurotoxin, anthrax toxin, von Willebrand Factor, biolayer interferometry, cryoSPARC

Relation: https://figshare.com/articles/media/Video_1_The_Chaperonin_GroEL_A_Versatile_Tool_for_Applied_Biotechnology_Platforms_AVI/6268913

الاتاحة: https://doi.org/10.3389/fmolb.2018.00046.s001
https://figshare.com/articles/media/Video_1_The_Chaperonin_GroEL_A_Versatile_Tool_for_Applied_Biotechnology_Platforms_AVI/6268913

المؤلفون: Alexandra J Machen, Tommi A. White, Mark T. Fisher, Narahari Akkaladevi

المصدر: Microscopy and Microanalysis. 23:1256-1257

مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, Chemistry, Anthrax toxin, Particle, Nanotechnology, Instrumentation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b9068ed68410286c065b4b44086944c7
https://doi.org/10.1017/s1431927617006948

المؤلفون: Alexandra J Machen, Alex A. Aimetti, Kristi S. Anseth

المصدر: Biomaterials. 30:6048-6054

مصطلحات موضوعية: Materials science, Light, Surface Properties, Biophysics, Serum albumin, Biocompatible Materials, Bioengineering, Peptide, Article, Polyethylene Glycols, Biomaterials, chemistry.chemical_compound, Drug Delivery Systems, PEG ratio, Animals, Humans, Sulfhydryl Compounds, Bovine serum albumin, Serum Albumin, Inflammation, chemistry.chemical_classification, biology, technology, industry, and agriculture, Proteins, Hydrogels, Enzymes, Kinetics, Photopolymer, chemistry, Biochemistry, Mechanics of Materials, Drug delivery, Self-healing hydrogels, Ceramics and Composites, biology.protein, Cattle, Muramidase, Leukocyte Elastase, Ethylene glycol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9311870c2009a5b05a0b80de57aea87
https://doi.org/10.1016/j.biomaterials.2009.07.043