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1Academic Journal
المؤلفون: Tânia F. Custódio, Maxime Killer, Dingquan Yu, Virginia Puente, Daniel P. Teufel, Alexander Pautsch, Gisela Schnapp, Marc Grundl, Jan Kosinski, Christian Löw
المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المؤلفون: Tânia Custódio, Maxime Killer, Dingquan Yu, Virginia Puente, Daniel Teufel, Alexander Pautsch, Gisela Schnapp, Marc Grundl, Jan Kosinski, Christian Loew
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3
المؤلفون: Alexander Weber, Marc Grundl, Markus R. Hermann, Alexander Pautsch, Christofer S. Tautermann
المصدر: Journal of Computer-Aided Molecular Design. 35:531-539
مصطلحات موضوعية: Index (economics), 010304 chemical physics, Chemistry, 01 natural sciences, Quantum chemistry, 0104 chemical sciences, Computer Science Applications, 010404 medicinal & biomolecular chemistry, Covalent bond, Computational chemistry, 0103 physical sciences, Drug Discovery, Electrophile, Reactivity (chemistry), Physical and Theoretical Chemistry
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4
المؤلفون: Sven O. Dahms, Gisela Schnapp, Martin Winter, Frank H. Büttner, Marco Schlepütz, Christian Gnamm, Alexander Pautsch, Hans Brandstetter
المصدر: ACS chemical biology. 17(4)
مصطلحات موضوعية: Furin, SARS-CoV-2, Molecular Medicine, General Medicine, Proprotein Convertases, Biochemistry, Antiviral Agents
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5
المؤلفون: Alexander Pautsch, Alexander Weber, Christofer S. Tautermann, Ferruccio Palazzesi, Marc Grundl
المصدر: Journal of Chemical Information and Modeling. 59:3565-3571
مصطلحات موضوعية: Models, Molecular, Acrylamides, Time Factors, 010304 chemical physics, Chemistry, General Chemical Engineering, Binding energy, Molecular Conformation, Ab initio, General Chemistry, Library and Information Sciences, 01 natural sciences, 0104 chemical sciences, Computer Science Applications, 010404 medicinal & biomolecular chemistry, Nucleophile, Computational chemistry, Covalent bond, 0103 physical sciences, Electrophile, Quantum Theory, Molecule, Reactivity (chemistry), HOMO/LUMO, Algorithms
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6
المؤلفون: Stefan Kochanek, Florian Stengel, Bin Huang, Qiang Guo, Jingdong Cheng, Marie Laura Niedermeier, Tatjana Engler, Wolfgang Baumeister, Rubén Fernández-Busnadiego, Alexander Pautsch, Melanie Maurer
المصدر: Structure (London, England : 1993). 29(8)
مصطلحات موضوعية: Models, Molecular, congenital, hereditary, and neonatal diseases and abnormalities, Huntingtin, animal diseases, Molecular Conformation, Mass Spectrometry, 03 medical and health sciences, Protein stability, Huntington's disease, Structural Biology, ddc:570, mental disorders, medicine, Humans, Cloning, Molecular, Molecular Biology, Gene, 030304 developmental biology, 0303 health sciences, Huntingtin Protein, Binding Sites, Chemistry, 030302 biochemistry & molecular biology, Cryoelectron Microscopy, Wild type, Protein level, Nuclear Proteins, medicine.disease, nervous system diseases, Cell biology, N-terminus, HEK293 Cells, Huntington Disease, nervous system, Peptides, Protein Binding
وصف الملف: application/pdf
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7
المؤلفون: Stefan Kochanek, Rubén Fernández-Busnadiego, Melanie Maurer, Wolfgang Baumeister, Florian Stengel, Marie Laura Niedermeier, Bin Huang, Jingdong Cheng, Qiang Guo, Tatjana Engler, Alexander Pautsch
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Huntingtin, nervous system, mental disorders, Wild type, Protein level, Biology, Global structure, Gene, nervous system diseases, Cell biology
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8
المؤلفون: Markus R, Hermann, Alexander, Pautsch, Marc A, Grundl, Alexander, Weber, Christofer S, Tautermann
المصدر: Journal of computer-aided molecular design. 35(4)
مصطلحات موضوعية: Acrylamides, Models, Chemical, Pharmaceutical Preparations, Acetamides, Drug Discovery, Quantum Theory
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9
المؤلفون: Ferruccio Palazzesi, Alexander Weber, Alexander Pautsch, Christofer S. Tautermann, Marc Grundl, Markus R. Hermann, Daniel Seeliger
المصدر: Journal of chemical information and modeling. 60(6)
مصطلحات موضوعية: Acrylamides, 010304 chemical physics, Drug discovery, General Chemical Engineering, Ab initio, Context (language use), General Chemistry, Library and Information Sciences, 01 natural sciences, 0104 chemical sciences, Computer Science Applications, Machine Learning, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, Warhead, Covalent bond, Computational chemistry, 0103 physical sciences, Functional group, Drug Discovery, Molecule, Reactivity (chemistry), Amino Acids
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10
المؤلفون: Tatjana Engler, Stefan Kochanek, Qiang Guo, Guenter Pfeifer, Bin Huang, Markus Otto, Patrick Oeckl, Wolfgang Baumeister, Jingdong Cheng, Manuel Seefelder, Alexander Pautsch, Rubén Fernández-Busnadiego, Franziska Moser, Melanie Maurer
المصدر: Nature
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Huntingtin, animal diseases, Static Electricity, Protein domain, Protein Structure, Secondary, Article, 03 medical and health sciences, Protein structure, Protein Domains, mental disorders, Huntingtin Protein, Humans, Nuclear protein, Multidisciplinary, Chemistry, Cryoelectron Microscopy, Nuclear Proteins, Protein phosphatase 2, nervous system diseases, Cell biology, Vesicular transport protein, Tetratricopeptide, 030104 developmental biology, nervous system, Hydrophobic and Hydrophilic Interactions, Protein Binding
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11
المؤلفون: Anna-Katharina Apel, Robert K.Y. Cheng, Christofer S. Tautermann, Michael Brauchle, Chia-Ying Huang, Alexander Pautsch, Michael Hennig, Herbert Nar, Gisela Schnapp
المصدر: Structure. 27:427-438.e5
مصطلحات موضوعية: Models, Molecular, Binding Sites, Protein Conformation, Protein Stability, Receptors, CCR2, THP-1 Cells, Rubredoxins, Crystallography, X-Ray, HEK293 Cells, Structural Biology, Drug Design, Mutation, Humans, Naphthyridines, Molecular Biology
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12
المؤلفون: Herbert Nar, Alexander Pautsch, Dirk Reinert, Dennis Fiegen, Stefan Hörer
مصطلحات موضوعية: Crystallography, Engineering, ComputingMethodologies_PATTERNRECOGNITION, Lead (geology), Process (engineering), Drug discovery, business.industry, Key (cryptography), Project management, business, Throughput (business)
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13
المؤلفون: Rozsa Schlenker-Herceg, Florian Colbatzky, Rolf Kaiser, Alexander Pautsch, Rudolf Binder, Claudia Dallinger, Lutz Wollin, John Edward Park, Gerald Juergen Roth, Frank Hilberg
المصدر: Successful Drug Discovery
مصطلحات موضوعية: 0301 basic medicine, business.industry, medicine.disease, 03 medical and health sciences, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Cancer research, Medicine, Nintedanib, business
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14
المؤلفون: Stefan Knapp, Benjamin E. Turk, Finn Wolfreys, Rebecca Konietzny, Kamal R. Abdul Azeez, Gisela Schnapp, Eidarus Salah, Paul Brennan, Hua Jane Lou, Roman Fischer, Alexander Pautsch, Cynthia Tallant, S. Mathea, Benedikt M. Kessler
مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Proto-Oncogene Proteins B-raf, Indoles, Calorimetry, Crystallography, X-Ray, Biochemistry, Article, 03 medical and health sciences, Adenosine Triphosphate, medicine, Humans, Phosphorylation, Vemurafenib, Protein kinase A, Peptide library, Protein Kinase Inhibitors, Genetics, Leucine Zippers, Sulfonamides, MAP kinase kinase kinase, Molecular Structure, Kinase, Chemistry, General Medicine, MAP Kinase Kinase Kinases, Phosphoproteins, 3. Good health, 030104 developmental biology, Drug Design, Cancer research, Molecular Medicine, Oligopeptides, Protein Kinases, medicine.drug
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15
المؤلفون: Frank Bernhard, Volker Dötsch, Alexander Pautsch, Stefan Haberstock, Christian Roos, Gisela Schnapp, Yvette Hoevels
المصدر: Protein Expression and Purification. 82:308-316
مصطلحات موضوعية: Base Sequence, Recombinant Fusion Proteins, Amino Acid Motifs, Gene Expression, Computational biology, Biology, Molecular biology, Chromatography, Affinity, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Template, Eukaryotic translation, Membrane protein, chemistry, Transcription (biology), Escherichia coli, Protein biosynthesis, Coding region, Amino Acid Sequence, Target protein, Codon, DNA, Plasmids, Subcellular Fractions, Biotechnology
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16The Implication of the First Agonist Bound Activated GPCR X-ray Structure on GPCR in Silico Modeling
المؤلفون: Christofer S. Tautermann, Alexander Pautsch
المصدر: ACS Medicinal Chemistry Letters. 2:414-418
مصطلحات موضوعية: Agonist, Chemistry, medicine.drug_class, In silico, Organic Chemistry, Protein Data Bank (RCSB PDB), Computational biology, Bioinformatics, Biochemistry, Small molecule, β2 adrenergic receptor, Drug Discovery, medicine, Active state, G protein-coupled receptor
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17
المؤلفون: Alexander Pautsch, Klaus Aktories, Martin Vogelsgesang
المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology. 374:347-360
مصطلحات موضوعية: Models, Molecular, rho GTP-Binding Proteins, Botulinum Toxins, RHOA, Protein Conformation, Bacterial Toxins, GTPase, medicine.disease_cause, Substrate Specificity, Protein structure, medicine, Animals, Humans, Mode of action, ADP Ribose Transferases, Pharmacology, biology, Molecular mass, Clostridium limosum, General Medicine, Cell biology, Biochemistry, Ral GTP-Binding Proteins, biology.protein, Clostridium botulinum, ral GTP-Binding Proteins
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18
المؤلفون: Martin Kolb, Katrin Hostettler, Susanne Stowasser, Alexander Pautsch, Eva Wex, Gisela Schnapp, Lutz Wollin
المصدر: The European Respiratory Journal
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Lung Diseases, Pathology, medicine.medical_specialty, Platelet-derived growth factor, Indoles, medicine.medical_treatment, Apoptosis, Review, Fibroblast growth factor, chemistry.chemical_compound, Idiopathic pulmonary fibrosis, Bleomycin, Fibrosis, Transforming Growth Factor beta, medicine, Animals, Humans, Enzyme Inhibitors, Lung, Cell Proliferation, Platelet-Derived Growth Factor, Clinical Trials as Topic, biology, business.industry, Growth factor, Cell Differentiation, Transforming growth factor beta, respiratory system, Fibroblasts, medicine.disease, Silicon Dioxide, Idiopathic Pulmonary Fibrosis, respiratory tract diseases, Extracellular Matrix, Fibroblast Growth Factors, chemistry, biology.protein, Nintedanib, business, Platelet-derived growth factor receptor
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19
المؤلفون: Akio Ebihara, Parag Surana, Bi-Cheng Wang, Michel O. Steinmetz, John Rose, Vincent Olieric, Andrea E. Prota, Deepak T. Nair, Valentina Cecatiello, Lirong Chen, Hua Zhang, Alexander Pautsch, Oliver Weichenrieder, Ezequiel Panepucci, Dayong Zhou, Tobias Weinert, Meitian Wang, Dianfan Li, Seiki Kuramitsu, Gisela Schnapp, Katja Bargsten, Federica Basilico, Jithesh Kottur, Andreas Boland, Nicole Howe, Martin Caffrey, Sandro Waltersperger, Sebastiano Pasqualato
المصدر: Nature methods. 12(2)
مصطلحات موضوعية: Models, Molecular, Materials science, Protein Conformation, Biochemistry, law.invention, Computational science, X-Ray Diffraction, law, Animals, Humans, Molecular Biology, Structure (mathematical logic), Anomalous diffraction, Macromolecular crystallography, Structural protein, Membrane Proteins, Cell Biology, Phaser, Synchrotron, DNA-Binding Proteins, Multiprotein Complexes, X-ray crystallography, Software, Synchrotrons, Biotechnology, Macromolecule
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20
المؤلفون: Horst Ahorn, Rudolf Hauptmann, Herbert Nar, Walter Spevak, Alexander Pautsch, Andreas Zoephel
المصدر: Structure. 9:955-965
مصطلحات موضوعية: MAP kinase kinase kinase, Biochemistry, Structural Biology, ROR1, Biophysics, ASK1, Cyclin-dependent kinase 9, Biology, Mitogen-activated protein kinase kinase, Molecular Biology, Tropomyosin receptor kinase C, MAP2K7, Proto-oncogene tyrosine-protein kinase Src
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