المؤلفون: Niklas Kolbe, Lorenz Hexemer, Lukas-Malte Bammert, Alexander Loewer, Mária Lukáčová-Medvid'ová, Stefan Legewie

المصدر: PLoS Computational Biology, Vol 18, Iss 6, p e1010266 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/3bb50be3c3134aec800dc9093ba0e88b

المؤلفون: Dhana Friedrich, Laura Friedel, Ana Finzel, Andreas Herrmann, Stephan Preibisch, Alexander Loewer

المصدر: Molecular Systems Biology, Vol 15, Iss 12, Pp 1-20 (2019)

مصطلحات موضوعية: cellular heterogeneity, DNA damage, p53 signaling, single‐cell analysis, stochastic transcription, Biology (General), QH301-705.5, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1744-4292

URL الوصول: https://doaj.org/article/3bc9af6ae33448de90effc61398d900a

المؤلفون: Fabian Konrath, Anna Mittermeier, Elena Cristiano, Jana Wolf, Alexander Loewer

المصدر: PLoS Computational Biology, Vol 16, Iss 6, p e1007901 (2020)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/c75db1df7f4a4c2896588f994787f4d4

المؤلفون: Jette Strasen, Uddipan Sarma, Marcel Jentsch, Stefan Bohn, Caibin Sheng, Daniel Horbelt, Petra Knaus, Stefan Legewie, Alexander Loewer

المصدر: Molecular Systems Biology, Vol 14, Iss 1, Pp 1-17 (2018)

مصطلحات موضوعية: cellular heterogeneity, mathematical modeling, signaling dynamics, single‐cell analysis, TGFβ‐SMAD signaling, Biology (General), QH301-705.5, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1744-4292

URL الوصول: https://doaj.org/article/5c6ce0a8d8d9404f8c43b4683108192e

المؤلفون: Caibin Sheng, Isabella-Hilda Mendler, Sara Rieke, Petra Snyder, Marcel Jentsch, Dhana Friedrich, Barbara Drossel, Alexander Loewer

المصدر: Cell Reports, Vol 27, Iss 1, Pp 48-58.e7 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221112471930347X; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/fe6e3846d07b41d2b884127f8c9a0d60

المؤلفون: Eric Batchelor, Alexander Loewer, Caroline Mock, Galit Lahav

المصدر: Molecular Systems Biology, Vol 7, Iss 1, Pp 1-8 (2011)

مصطلحات موضوعية: DNA damage, dynamics, excitability, feedback, live‐cell imaging, Biology (General), QH301-705.5, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1744-4292

URL الوصول: https://doaj.org/article/6afb3fc31a514c0caf7c4dd390972814

المؤلفون: Grégoire Jean-Baptiste Philippe, Yen-Hua Huang, Anna Mittermeier, Christopher J. Brown, Quentin Kaas, Siti Radhiah Ramlan, Conan K. Wang, David Lane, Alexander Loewer, Sónia Troeira Henriques, David J. Craik

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, x interactions using, reach intracellular targets, promising drug modalities, penetrating peptide peptides, penetrating peptide cr10, peptide blocking p53, improve intracellular delivery, grafted cyclotide conjugated, cancer cells using, lead peptide, p53 pathway, mcf10a cells, stabilizing scaffold, micromolar concentration, lead cyclotide, inhibitory activity, inducing apoptosis, fold improvement, cytosolic delivery

Relation: https://figshare.com/articles/journal_contribution/Delivery_to_and_Reactivation_of_the_p53_Pathway_in_Cancer_Cells_Using_a_Grafted_Cyclotide_Conjugated_with_a_Cell-Penetrating_Peptide/24942836

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01682.s001
https://figshare.com/articles/journal_contribution/Delivery_to_and_Reactivation_of_the_p53_Pathway_in_Cancer_Cells_Using_a_Grafted_Cyclotide_Conjugated_with_a_Cell-Penetrating_Peptide/24942836

المؤلفون: Grégoire J.-B. Philippe (7295600), Anna Mittermeier (9033881), Nicole Lawrence (2376817), Yen-Hua Huang (409275), Nicholas D. Condon (7295603), Alexander Loewer (5015150), David J. Craik (13753), Sónia T. Henriques (7310813)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, intracellular cancer pathways, cancer progression, MDMX, affinity binder peptides, endocytic pathway, cyclic cell-penetrating peptides, throughput screening, cancer cells, cell line, cell membrane permeation, 1 μ M, angler strategy, p 53 pathway, anticancer therapeutics, HCT, cytosol delivery, cell entry mechanism, nonpermeable anticancer peptides

Relation: https://figshare.com/articles/journal_contribution/Angler_Peptides_Macrocyclic_Conjugates_Inhibit_p53_MDM2_X_Interactions_and_Activate_Apoptosis_in_Cancer_Cells/13704816

الاتاحة: https://doi.org/10.1021/acschembio.0c00988.s001

المؤلفون: Elina Wiechens, Flavia Vigliotti, Konstantin Riege, Alena van Bömmel, Katjana Schwab, Ivonne Görlich, Martin Bens, Robert Schwarz, Arne Sahm, Marco Groth, Alexander Loewer, Steve Hoffmann, Martin Fischer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d6d3b3396fd4a11fd6948f20a304b513
https://doi.org/10.21203/rs.3.rs-2803901/v1

المؤلفون: Stefan Bohn, Lorenz Hexemer, Zixin Huang, Laura Strohmaier, Sonja Lenhardt, Stefan Legewie, Alexander Loewer

المصدر: Proceedings of the National Academy of Sciences. 120

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f5c9e30e272dd48c59680520af79561c
https://doi.org/10.1073/pnas.2210891120

المؤلفون: Fabian Konrath, Alexander Loewer, Jana Wolf

المصدر: Methods in Molecular Biology ISBN: 9781071630075

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b2b01b03f36b43afef35329ade25d869
https://doi.org/10.1007/978-1-0716-3008-2_12

المؤلفون: Laura Friedel, Alexander Loewer

المصدر: The FEBS Journal. 289:40-52

مصطلحات موضوعية: 0301 basic medicine, Cell cycle checkpoint, DNA Repair, Cell, Apoptosis, Genotoxic Stress, Biology, Biochemistry, Genomic Instability, law.invention, 03 medical and health sciences, 0302 clinical medicine, Single-cell analysis, law, medicine, Humans, Cell Lineage, Promoter Regions, Genetic, Molecular Biology, Gene, Genome, Cell Cycle, Promoter, Cell Biology, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Context specific, Suppressor, Tumor Suppressor Protein p53, Neuroscience, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3cde893d38728c26fecc8de3e2b29d
https://doi.org/10.1111/febs.15767

المؤلفون: Zixin, Huang, Alexander, Loewer

المصدر: Methods in molecular biology (Clifton, N.J.). 2488

مصطلحات موضوعية: Technology, Humans, CRISPR-Cas Systems, Cell Line, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::eab404aeba744b35d2cb028efe15182e
https://pubmed.ncbi.nlm.nih.gov/35347684

المؤلفون: Zixin Huang, Alexander Loewer

المصدر: Methods in Molecular Biology ISBN: 9781071622766

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0709af62022bbff4cf69649b40ed1f15
https://doi.org/10.1007/978-1-0716-2277-3_7

المؤلفون: Niklas Kolbe (11998394), Lorenz Hexemer (11998718), Lukas-Malte Bammert (11998654), Alexander Loewer (5015150), Mária Lukáčová-Medviďová (11998661), Stefan Legewie (65841)

مصطلحات موضوعية: Computational Biology, SMAD signaling, TGFb, stochastic modeling, Systems biology

Relation: https://figshare.com/articles/figure/Autocorrelation_of_nuc_cyt_SMAD2_ratio/19064561

الاتاحة: https://doi.org/10.6084/m9.figshare.19064561.v1

المؤلفون: Niklas Kolbe (11998394), Lorenz Hexemer (11998574), Lukas-Malte Bammert (11998654), Alexander Loewer (5015150), Mária Lukáčová-Medviďová (11998661), Stefan Legewie (65841)

مصطلحات موضوعية: Computational Biology, SMAD signaling, tgfb, stochastic modeling, Systems biology

Relation: https://figshare.com/articles/figure/Log-likelihood_and_Akaike_information_criterion_of_block_models/19064558

الاتاحة: https://doi.org/10.6084/m9.figshare.19064558.v1

المؤلفون: Niklas Kolbe (11998394), Lorenz Hexemer (11998574), Lukas-Malte Bammert (11998654), Alexander Loewer (5015150), Mária Lukáčová-Medviďová (11998661), Stefan Legewie (65841)

مصطلحات موضوعية: Computational Biology, SMAD signaling, TGF β, Stochastic modeling, Systems biology

Relation: https://figshare.com/articles/figure/Comparison_to_full_and_hybrid_stochastic_simulation_techniques/19064621

الاتاحة: https://doi.org/10.6084/m9.figshare.19064621.v1

المؤلفون: Niklas, Kolbe, Lorenz, Hexemer, Lukas-Malte, Bammert, Alexander, Loewer, Mária, Lukáčová-Medvid'ová, Stefan, Legewie

المصدر: PLoS computational biology. 18(6)

مصطلحات موضوعية: Cell Nucleus, Transforming Growth Factor beta, Smad Proteins, Endosomes, Receptors, Transforming Growth Factor beta, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5f86731965b3f03d8a024b92946cd664
https://pubmed.ncbi.nlm.nih.gov/35759468

المؤلفون: Nicole Lawrence, Alexander Loewer, Grégoire J.B. Philippe, Yen-Hua Huang, Anna Mittermeier, Sónia Troeira Henriques, Nicholas D. Condon, David J. Craik

المصدر: ACS chemical biology. 16(2)

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, MDMX, Erythrocytes, Endosome, Endocytic cycle, Cell, Antineoplastic Agents, Apoptosis, Cell-Penetrating Peptides, 01 natural sciences, Biochemistry, Peptides, Cyclic, Cell membrane, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Amino Acid Sequence, Cell Proliferation, 010405 organic chemistry, Chemistry, Proto-Oncogene Proteins c-mdm2, General Medicine, 0104 chemical sciences, 3. Good health, Cell biology, Cytosol, 030104 developmental biology, medicine.anatomical_structure, Drug Design, Cancer cell, Leukocytes, Mononuclear, Molecular Medicine, Drug Screening Assays, Antitumor, Tumor Suppressor Protein p53, Intracellular, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b129a78d275a500bf2ede23aa5de6b10
https://pubmed.ncbi.nlm.nih.gov/33533253

المؤلفون: Fabian Konrath, Anna Mittermeier, Elena Cristiano, Jana Wolf, Alexander Loewer

المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 6, p e1007901 (2020)

مصطلحات موضوعية: Cancer Research, Computer and Information Sciences, QH301-705.5, Research and Analysis Methods, Biochemistry, Stress Signaling Cascade, Fluorescence Microscopy, Cell Signaling, Genetics, Biology (General), Post-Translational Modification, Phosphorylation, Cellular Stress Responses, Microscopy, Messenger RNA, NF-kappa B, Reproducibility of Results, Biology and Life Sciences, Proteins, Light Microscopy, Cell Biology, DNA, Signaling Cascades, Signaling Networks, Nucleic acids, Cellular Crosstalk, Cell Processes, RNA, DNA damage, Single-Cell Analysis, Tumor Suppressor Protein p53, Network Analysis, Signal Transduction, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::554c5de40c0160dc0f4b4cd8345d19fb
https://pubmed.ncbi.nlm.nih.gov/32589666