المؤلفون: Iris Wu, Aliya Zeng, Amara Greer-Short, J. Alex Aycinena, Anley E. Tefera, Reva Shenwai, Farshad Farshidfar, Melissa Van Pell, Emma Xu, Chris Reid, Neshel Rodriguez, Beatriz Lim, Tae Won Chung, Joseph Woods, Aquilla Scott, Samantha Jones, Cristina Dee-Hoskins, Carolina G. Gutierrez, Jessie Madariaga, Kevin Robinson, Yolanda Hatter, Renee Butler, Stephanie Steltzer, Jaclyn Ho, James R. Priest, Xiaomei Song, Frank Jing, Kristina Green, Kathryn N. Ivey, Timothy Hoey, Jin Yang, Zhihong Jane Yang

المصدر: Communications Medicine, Vol 4, Iss 1, Pp 1-19 (2024)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2730-664X

URL الوصول: https://doaj.org/article/44e0349c7b784de384ccd674ac140a80

المؤلفون: Iris Wu, Amara Greer-Short, Alex Aycinena, Anley Tefera, Reva Shenwai, Farshad Farshidfar, Melissa Van Pell, Emma Xu, Chris Reid, Neshel Getuiza, Beatriz Lim, Tae Won Chung, Renee Butler, Stephanie Steltzer, Jaclyn Ho, Kristina Green, Kathryn Ivey, Timothy Hoey, Jin Yang, Aliya Zeng, Zhihong Yang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c5608f6ce5c259894d92bef573a9364d
https://doi.org/10.21203/rs.3.rs-2958419/v1

المؤلفون: Matthew T. Burger, Jocelyn Holash, Richard Zang, J. Alex Aycinena, Cornelia Bellamacina, Mika Lindvall, Gisele Nishiguchi, Jiong Lan, Wooseok Han, Christopher Wilson, Joerg Trappe, Peter Drueckes, Estelle Pfister, Audrey Kauffmann, Christine Fritsch, Tiffany Tsang, Jamie Narberes, Robert Warne, Paul Feucht, Michael Doyle, Jianjun Yu, Julie Chan, Stephen Basham, Xiao-Hong Niu, Jing Lu, Yumin Dai, Tatiana Zavorotinskaya, Marjorie Ison, Christie Fanton, Joseph Castillo, Min Chen, Yingyun Wang, John L. Langowski, Pablo D. Garcia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b7a0911566c282b44322df88773977
https://doi.org/10.1158/1078-0432.c.6522398

المؤلفون: Matthew T. Burger, Jocelyn Holash, Richard Zang, J. Alex Aycinena, Cornelia Bellamacina, Mika Lindvall, Gisele Nishiguchi, Jiong Lan, Wooseok Han, Christopher Wilson, Joerg Trappe, Peter Drueckes, Estelle Pfister, Audrey Kauffmann, Christine Fritsch, Tiffany Tsang, Jamie Narberes, Robert Warne, Paul Feucht, Michael Doyle, Jianjun Yu, Julie Chan, Stephen Basham, Xiao-Hong Niu, Jing Lu, Yumin Dai, Tatiana Zavorotinskaya, Marjorie Ison, Christie Fanton, Joseph Castillo, Min Chen, Yingyun Wang, John L. Langowski, Pablo D. Garcia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cf370c3ede2546f0f7aab800bf1d63
https://doi.org/10.1158/1078-0432.22452158.v1

المؤلفون: Alex Aycinena, Yu Ding, Audry Kauffmann, Tatiana Zavorotinskaya, Amy Lambert, John L. Langowski, Julie Chan, Cornelia Bellamacina, Robert Lowell Simmons, Yumin Dai, Min Y. Chen, Christine Fritsch, Gordana Atallah, Elaine Ginn, Victoriano Tamez, Matthew Burger, Kristine Muller, Richard Zang, Paul Feucht, Joseph Castillo, Estelle Pfister, K. Gary Vanasse, Mika Lindvall, Pablo Garcia, Michelle Mathur, Wooseok Han, Gisele Nishiguchi, Jocelyn Holash, Yingyun Wang, Kay Huh, Zhang Yanchen, Steve Basham, Jiong Lan

المصدر: Journal of Medicinal Chemistry. 58:8373-8386

مصطلحات موضوعية: Chemistry, Kinase, Myeloid leukemia, Cancer, medicine.disease, Virology, In vitro, Clinical trial, Leukemia, In vivo, hemic and lymphatic diseases, Drug Discovery, medicine, Cancer research, Molecular Medicine, Multiple myeloma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3fbae38e8687d6cf1c7760d3d1539a2b
https://doi.org/10.1021/acs.jmedchem.5b01275

المؤلفون: Biplob Mitra, Prajwal Thool, Jhalak Patel, Kuldip Patel, William Bowen, Jianmin Li, Shyam Karki, Anjali Agarwal, Saikishore Meruva, J. Alex Aycinena

المصدر: International Journal of Pharmaceutics. 574:118905

مصطلحات موضوعية: Materials science, Chemistry, Pharmaceutical, Drug Compounding, Administration, Oral, Pharmaceutical Science, Excipient, Ibuprofen, 02 engineering and technology, 030226 pharmacology & pharmacy, Dosage form, Mini tablets, 03 medical and health sciences, 0302 clinical medicine, Pressure, medicine, Dosing, Particle Size, Flexibility (engineering), Weight control, 021001 nanoscience & nanotechnology, Solubility, Particle size, 0210 nano-technology, Tablets, medicine.drug, Biomedical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3821f85f0724ae5143e81db2fb82ac
https://doi.org/10.1016/j.ijpharm.2019.118905

المؤلفون: Young Kim, Tove Tuntland, H. Martin Seidel, Thomas H. Marsilje, Nanxin Li, Wei Pei, You-Qun He, Xiaoming Cui, Wendy Richmond, Markus Warmuth, Auzon Steffy, Alex Aycinena, Sungjoon Kim, W. Perry Gordon, Donald S. Karanewsky, AnneMarie Culazzo Pferdekamper, Jin Yunho, Jonathan Chang, Ruo Steensma, Jennifer L. Harris, Bo Liu, Sean B. Joseph, Yelena Sarkisova, Christian C. Lee, Todd Groessl, Bei Chen, Wenshuo Lu, Chopiuk Greg, Tao Jiang, Kevin Johnson, Tetsuo Uno, Pierre-Yves Michellys, Jiqing Jiang, Andrew Phimister, Allen G. Li, Nathanael S. Gray, Badry Bursulaya, Frank Sun, Yongqin Wan, Jie Li

المصدر: Journal of Medicinal Chemistry. 56:5675-5690

مصطلحات موضوعية: Pyrimidine, Brigatinib, Ceritinib, Chemistry, medicine.drug_class, Rational design, Pharmacology, ALK inhibitor, chemistry.chemical_compound, In vivo, hemic and lymphatic diseases, Drug Discovery, medicine, Molecular Medicine, Anaplastic lymphoma kinase, Structure–activity relationship, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d85881c6ed23d1f9f401bd84a59439c2
https://doi.org/10.1021/jm400402q

المؤلفون: Matthew T, Burger, Gisele, Nishiguchi, Wooseok, Han, Jiong, Lan, Robert, Simmons, Gordana, Atallah, Yu, Ding, Victoriano, Tamez, Yanchen, Zhang, Michelle, Mathur, Kristine, Muller, Cornelia, Bellamacina, Mika K, Lindvall, Richard, Zang, Kay, Huh, Paul, Feucht, Tatiana, Zavorotinskaya, Yumin, Dai, Steve, Basham, Julie, Chan, Elaine, Ginn, Alex, Aycinena, Jocelyn, Holash, Joseph, Castillo, John L, Langowski, Yingyun, Wang, Min Y, Chen, Amy, Lambert, Christine, Fritsch, Audry, Kauffmann, Estelle, Pfister, K Gary, Vanasse, Pablo D, Garcia

المصدر: Journal of medicinal chemistry. 58(21)

مصطلحات موضوعية: Models, Molecular, Leukemia, Myeloid, Acute, Mice, Halogenation, Proto-Oncogene Proteins c-pim-1, Cell Line, Tumor, Proto-Oncogene Proteins, Animals, Humans, Protein Serine-Threonine Kinases, Picolinic Acids, Amides, Protein Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::520e2275f65794da2b12343a31ae7d5e
https://pubmed.ncbi.nlm.nih.gov/26505898

المؤلفون: Christine Fritsch, Cornelia Bellamacina, Yingyun Wang, Christine D. Wilson, Yumin Dai, John L. Langowski, Xiaohong Niu, Julie Chan, Marjorie Ison, Estelle Pfister, Jamie Narberes, Mika Lindvall, Christie Fanton, Gisele Nishiguchi, Tiffany Tsang, Warne Robert L, J. Alex Aycinena, Joseph Castillo, Pablo Garcia, Peter Drueckes, Stephen Basham, Wooseok Han, Richard Zang, Jianjun Yu, Paul Feucht, Min Chen, Matthew Burger, Joerg Trappe, Jing Lu, Audrey Kauffmann, Jiong Lan, Tatiana Zavorotinskaya, Michael Doyle, Jocelyn Holash

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 20(7)

مصطلحات موضوعية: Cancer Research, Biology, Pharmacology, Protein Serine-Threonine Kinases, Myelogenous, Mice, Proto-Oncogene Proteins c-pim-1, hemic and lymphatic diseases, Cell Line, Tumor, Proto-Oncogene Proteins, medicine, Animals, Humans, Kinase activity, Phosphorylation, Protein Kinase Inhibitors, Multiple myeloma, TOR Serine-Threonine Kinases, medicine.disease, Xenograft Model Antitumor Assays, Lymphoma, Leukemia, Oncology, Cell culture, Hematologic Neoplasms, Cytarabine, medicine.drug, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794cbe2432b36c7ce3bc09182e92487a
https://pubmed.ncbi.nlm.nih.gov/24474669

المؤلفون: Thomas H, Marsilje, Wei, Pei, Bei, Chen, Wenshuo, Lu, Tetsuo, Uno, Yunho, Jin, Tao, Jiang, Sungjoon, Kim, Nanxin, Li, Markus, Warmuth, Yelena, Sarkisova, Frank, Sun, Auzon, Steffy, AnneMarie C, Pferdekamper, Allen G, Li, Sean B, Joseph, Young, Kim, Bo, Liu, Tove, Tuntland, Xiaoming, Cui, Nathanael S, Gray, Ruo, Steensma, Yongqin, Wan, Jiqing, Jiang, Greg, Chopiuk, Jie, Li, W Perry, Gordon, Wendy, Richmond, Kevin, Johnson, Jonathan, Chang, Todd, Groessl, You-Qun, He, Andrew, Phimister, Alex, Aycinena, Christian C, Lee, Badry, Bursulaya, Donald S, Karanewsky, H Martin, Seidel, Jennifer L, Harris, Pierre-Yves, Michellys

المصدر: Journal of medicinal chemistry. 56(14)

مصطلحات موضوعية: Male, Clinical Trials, Phase I as Topic, Receptor Protein-Tyrosine Kinases, Xenograft Model Antitumor Assays, Rats, Macaca fascicularis, Structure-Activity Relationship, Clinical Trials, Phase II as Topic, Dogs, Pyrimidines, Neoplasms, Animals, Humans, Anaplastic Lymphoma Kinase, Sulfones, Protein Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dbf15d2b63a657b955fb85a1fda7239b
https://pubmed.ncbi.nlm.nih.gov/23837797