المؤلفون: Alessandra Cipriano, Ram P. Kapil, Mingyan Zhou, Manjunath S. Shet, Stephen C. Harris, Glen Apseloff, Garth T. Whiteside

المصدر: Frontiers in Pharmacology, Vol 15 (2024)

مصطلحات موضوعية: sunobinop, insomnia, next-day residual effects, healthy participants, nociceptin/orphanin FQ, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1432902/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/24d290c4517148d2aff8f523111f52ed

المؤلفون: Ciro Milite, Giorgio Amendola, Alessio Nocentini, Silvia Bua, Alessandra Cipriano, Elisabetta Barresi, Alessandra Feoli, Ettore Novellino, Federico Da Settimo, Claudiu T. Supuran, Sabrina Castellano, Sandro Cosconati, Sabrina Taliani

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1697-1710 (2019)

مصطلحات موضوعية: carbonic anhydrase inhibitors, benzimidazole-sulfonamides, reduced flexibility approach, isoform-selective inhibitors, molecular docking, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/58d8627f9d1b40a0bf23a6ac5f027834

المؤلفون: Alessandra Cipriano, Ciro Milite, Alessandra Feoli, Monica Viviano, Giacomo Pepe, Pietro Campiglia, Giuliana Sarno, Sarah Picaud, Satomi Imaide, Nikolai Makukhin, Panagis Filippakopoulos, Alessio Ciulli, Sabrina Castellano, Gianluca Sbardella

المصدر: ChemMedChem. 17

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9b5edef4d66f5f45de556d8c894a9297
https://doi.org/10.1002/cmdc.202200528

المؤلفون: Giulia Iannelli, Ciro Milite, Nils Marechal, Vincent Cura, Luc Bonnefond, Nathalie Troffer-Charlier, Alessandra Feoli, Donatella Rescigno, Yalong Wang, Alessandra Cipriano, Monica Viviano, Mark T. Bedford, Jean Cavarelli, Sabrina Castellano, Gianluca Sbardella

المصدر: Journal of medicinal chemistry. 65(17)

مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, Design, Histone H3, RGG box, Assay, Small-molecule inhibitors, Histone/Protein methyltransferase, Functional insights, Coactivator, Methylation, CARM1, Arginine, Drug Discovery, Molecular Medicine, Enzyme Inhibitors, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ea2f58745b7c33c930c5c8dc029561
https://pubmed.ncbi.nlm.nih.gov/35482954

المؤلفون: Alessandra Cipriano, Ciro Milite, Alessandra Feoli, Monica Viviano, Giacomo Pepe, Pietro Campiglia, Giuliana Sarno, Sarah Picaud, Satomi Imaide, Nikolai Makukhin, Panagis Filippakopoulos, Alessio Ciulli, Sabrina Castellano, Gianluca Sbardella

مصطلحات موضوعية: Male, Pharmacology, Sulfonamides, Bioisosteres, Organic Chemistry, Imidazoles, Nuclear Proteins, Bromodomain, Cell Cycle Proteins, Structure-activity relationships, Biochemistry, Benzimidazole-6-sulfonamide, Selectivity, Drug Discovery, Benzo(a)pyrene, Humans, Molecular Medicine, Benzimidazoles, General Pharmacology, Toxicology and Pharmaceutics, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97485ad4f5fc3bfd314a88b32c4c543
http://hdl.handle.net/11386/4803392

المؤلفون: Alessandra Feoli, Monica Viviano, Alessandra Cipriano, Ciro Milite, Sabrina Castellano, Gianluca Sbardella

المصدر: RSC chemical biology. 3(4)

مصطلحات موضوعية: STRUCTURE-BASED DESIGN, C-TERMINAL DOMAIN, SET-DOMAIN, HISTONE H3 METHYLTRANSFERASE, SMALL-MOLECULE INHIBITORS, STRUCTURE-BASED OPTIMIZATION, PROTEIN-PROTEIN INTERACTION, DOMAIN-CONTAINING PROTEIN, POTENT DOT1L INHIBITORS, MENIN-MLL INTERACTION, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Chemistry (miscellaneous), Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7a9a90fd4ee08760dcb53e789ff40e
https://pubmed.ncbi.nlm.nih.gov/35441141

المؤلفون: Gianluca Sbardella, Alessandra Cipriano, Alessio Ciulli

مصطلحات موضوعية: 0301 basic medicine, Epigenomics, Models, Molecular, Chemical biology, Computational biology, 010402 general chemistry, 01 natural sciences, Biochemistry, Analytical Chemistry, Epigenesis, Genetic, Small Molecule Libraries, 03 medical and health sciences, Non-histone protein, Drug Discovery, Animals, Humans, Epigenetics, biology, Chemistry, Industrial research, Small molecule, 0104 chemical sciences, Bromodomain, Histone Code, 030104 developmental biology, Histone, Drug Design, biology.protein, Posttranslational modification, Peptides, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e404f9771f03fa7ac28f53509056bed9
http://hdl.handle.net/11386/4748908

المؤلفون: Catherine Munera, Yi Wang, Alessandra Cipriano, Stephen C. Harris

المصدر: The Journal of Clinical Pharmacology. 56:1263-1271

مصطلحات موضوعية: Pharmacology, Transdermal patch, business.industry, Healthy subjects, Area under the curve, Crossover study, 03 medical and health sciences, 0302 clinical medicine, Opioid, 030202 anesthesiology, Anesthesia, medicine, Pharmacology (medical), business, 030217 neurology & neurosurgery, Buprenorphine, medicine.drug, Transdermal, Absolute bioavailability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::43136c3fd89fe4269fa626c4ffadad62
https://doi.org/10.1002/jcph.718

المؤلفون: Xiaodong Cheng, Alessandra Cipriano, Ettore Novellino, John R. Horton, Giorgio Amendola, Giacomo Pepe, Donatella Rescigno, Gianluca Sbardella, Sabrina Castellano, Alessandra Feoli, Sandro Cosconati, Monica Viviano, Vincenzo Pisapia, Ciro Milite

المساهمون: Milite, C., Feoli, A., Horton, J. R., Rescigno, D., Cipriano, A., Pisapia, V., Viviano, M., Pepe, G., Amendola, G., Novellino, E., Cosconati, S., Cheng, X., Castellano, S., Sbardella, G.

المصدر: J Med Chem

مصطلحات موضوعية: Cell Membrane Permeability, Methyltransferase, GLP, Drug Evaluation, Preclinical, SELECTIVE INHIBITORS, G9A INHIBITOR, Crystallography, X-Ray, 01 natural sciences, DNA methyltransferase, Article, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, EHMT1, Cell Line, Tumor, Drug Discovery, Quinazoline, Humans, ASSAY, Enzyme Inhibitors, DNA METHYLATION, 030304 developmental biology, 0303 health sciences, Molecular Structure, Rational design, CHEMICAL PROBE, Histone-Lysine N-Methyltransferase, G9A-LIKE PROTEIN, Small molecule, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Diazepine, Biochemistry, chemistry, HISTONE/PROTEIN METHYLTRANSFERASE, Blood-Brain Barrier, Drug Design, Molecular Medicine, SMALL-MOLECULE INHIBITORS, H3K9 METHYLATION

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1d25b5b950d14a80d3f73c7a033dc1
http://hdl.handle.net/11386/4720855

المؤلفون: Gregory Michels, Stephen C. Harris, Manjunath S. Shet, Ram P. Kapil, Sabiha A. Mondal, Alessandra Cipriano, Kristen Friedman

المصدر: Clinical Therapeutics. 37:2286-2296

مصطلحات موضوعية: Adult, Male, Chemistry, Pharmaceutical, Pharmacology, Placebo, Drug Administration Schedule, 03 medical and health sciences, 0302 clinical medicine, Cytochrome P-450 Enzyme System, Double-Blind Method, Pharmacokinetics, Cytochrome P-450 CYP2D6 Inhibitors, CYP2D6 inhibitor, medicine, Humans, Hydromorphone, Pharmacology (medical), Hydrocodone, 030212 general & internal medicine, drug–drug interaction, Active metabolite, Cross-Over Studies, business.industry, Norhydrocodone, Crossover study, Healthy Volunteers, Paroxetine, Opioid, Area Under Curve, Delayed-Action Preparations, opioid, Drug Therapy, Combination, Female, business, pharmacokinetics, 030217 neurology & neurosurgery, Tablets, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2aaef456a2b92cfcba8140e7c05b0b1
https://doi.org/10.1016/j.clinthera.2015.08.007

المؤلفون: Glen Apseloff, Manjunath S. Shet, Salvatore V. Colucci, Joseph P Kitzmiller, Gregory Michels, Ram P. Kapil, Stephen C. Harris, Alessandra Cipriano, Kristen Friedman

المصدر: Journal of Pain and Symptom Management. 46:65-75

مصطلحات موضوعية: Adult, Adolescent, Analgesic, Context (language use), Administration, Cutaneous, law.invention, Pharmacokinetics, Randomized controlled trial, law, medicine, Humans, Adverse effect, General Nursing, Transdermal, medicine.diagnostic_test, business.industry, Middle Aged, Buprenorphine, Analgesics, Opioid, Pulse oximetry, Anesthesiology and Pain Medicine, Anesthesia, Neurology (clinical), business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73800ced8296f1588655123d3d55cdc
https://doi.org/10.1016/j.jpainsymman.2012.06.014

المؤلفون: Peter J. Perrino, Sarah A. O’Keefe, Salvatore V. Colucci, Stephen C. Harris, Alessandra Cipriano, Ram P. Kapil, Gregory Michels, Robert J. Noveck, Manjunath S. Shet

المصدر: Clinical Drug Investigation. 32:583-592

مصطلحات موضوعية: Adult, Adolescent, Cmax, Pharmacology, Placebo, Administration, Cutaneous, Placebos, chemistry.chemical_compound, Young Adult, Pharmacokinetics, Double-Blind Method, medicine, Humans, Pharmacology (medical), Norbuprenorphine, Cross-Over Studies, business.industry, General Medicine, Middle Aged, Crossover study, Erythromycin breath test, Buprenorphine, Ketoconazole, chemistry, Breath Tests, Anesthesia, Area Under Curve, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2427dc266e74222a773952de29aaafce
https://doi.org/10.2165/11633060-000000000-00000

المؤلفون: Yi, Wang, Alessandra, Cipriano, Catherine, Munera, Stephen C, Harris

المصدر: Journal of clinical pharmacology. 56(10)

مصطلحات موضوعية: Adult, Male, Cross-Over Studies, Dose-Response Relationship, Drug, Transdermal Patch, Administration, Cutaneous, Healthy Volunteers, Buprenorphine, Analgesics, Opioid, Young Adult, Double-Blind Method, Humans, Female, Biotransformation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::33dcac4274fe131cf1512905fd35656d
https://pubmed.ncbi.nlm.nih.gov/26865472

المؤلفون: Danlin Wu, Stephen C. Harris, Alessandra Cipriano, Vijay Vashi, Ahmed El-Tahtawy

المصدر: The Journal of Clinical Pharmacology. 45:547-554

مصطلحات موضوعية: Adult, Male, Biological Availability, Pharmacology, Drug Administration Schedule, Dosage form, law.invention, Food-Drug Interactions, Pharmacokinetics, law, medicine, Humans, Hydromorphone, Pharmacology (medical), Cross-Over Studies, Clinical pharmacology, Dose-Response Relationship, Drug, Chemistry, Bioavailability, Analgesics, Opioid, Area Under Curve, Delayed-Action Preparations, Anesthesia, Female, HYDROMORPHONE HYDROCHLORIDE, Extended release, Once daily, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755e3935ae59297032ef1aa3eb736b50
https://doi.org/10.1177/0091270005274552

المؤلفون: Alessandra Cipriano

المصدر: Folia Primatologica. 73:21-31

مصطلحات موضوعية: Dental Cementum, Age Factors, Animals, Wild, Hominidae, Anatomy, Biology, Adaptation, Physiological, Cold Temperature, stomatognathic diseases, Investigation methods, medicine.anatomical_structure, stomatognathic system, medicine, Cold winter, Animals, Animals, Zoo, Animal Science and Zoology, Seasons, Dental cementum, Cementum, Cementogenesis, Tooth Calcification, Ecology, Evolution, Behavior and Systematics, Cold stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce75454c2a23113ee03841cc44916df7
https://doi.org/10.1159/000060416

المؤلفون: Ram P. Kapil, Kristen Friedman, Alessandra Cipriano, Gregory Michels, Manjunath Shet, Sabiha Mondal, Stephen C. Harris

المصدر: Clinical Therapeutics. 38:228-229

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::99c7d155c92828ae5fe09770bb8b7bf7
https://doi.org/10.1016/j.clinthera.2015.10.024

المؤلفون: Jim X. Sun, Elliot Redalieu, Alessandra Cipriano, John M. Morgan, Jill C. Joshi, Anthony J. Piraino, Keith K. H. Chan

المصدر: The Journal of Clinical Pharmacology. 35:390-397

مصطلحات موضوعية: Male, Pharmacology, Cross-Over Studies, Nitrogen Isotopes, Chemistry, Biological Availability, Metabolism, Administration, Cutaneous, Crossover study, Dosage form, Bioavailability, Nitroglycerin, Route of administration, Drug Stability, Pharmacokinetics, cardiovascular system, Nitro, Humans, Pharmacology (medical), Infusions, Intravenous, circulatory and respiratory physiology, Transdermal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef76525691d96e69802b44f84497d8b
https://doi.org/10.1002/j.1552-4604.1995.tb04079.x

المؤلفون: Ram P. Kapil, Naama Levy-Cooperman, Stephen C. Harris, Salvatore V. Colucci, Talar Hopyan, Pierre Geoffroy, Alessandra Cipriano

المصدر: Pain Medicine: The Official Journal of the American Academy of Pain Medicine

مصطلحات موضوعية: Abuse Potential, Adult, Male, Visual analogue scale, Pain, Poison control, Placebo, HYD, Drug Administration Schedule, Young Adult, Double-Blind Method, Pharmacokinetics, Original Research Articles, medicine, Humans, Hydrocodone, Administration, Intranasal, Cross-Over Studies, Illicit Drugs, business.industry, Abuse Deterrent, Chronic pain, General Medicine, Middle Aged, Opioid-Related Disorders, medicine.disease, Crossover study, Analgesics, Opioid, Anesthesiology and Pain Medicine, Opioid, Delayed-Action Preparations, Anesthesia, Female, Neurology (clinical), Powders, GENERAL SECTION, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd547ca560d9f4e4591f735c2563de8
https://doi.org/10.1093/pm/pnv004

المؤلفون: D. Wu, Ahmed El-Tahtawy, Stephen C. Harris, Vijay Vashi, Alessandra Cipriano

المصدر: The Journal of Pain. 5:S66

مصطلحات موضوعية: Clinical pharmacology, business.industry, Persistent pain, Renal function, Pharmacology, Multiple dose, law.invention, Anesthesiology and Pain Medicine, Neurology, Pharmacokinetics, Oral administration, law, Anesthesia, Medicine, In patient, HYDROMORPHONE HYDROCHLORIDE, Neurology (clinical), Extended release, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d316ddf35b3da6f2d6bdbce6cd7e1f4
https://doi.org/10.1016/j.jpain.2004.02.231

المؤلفون: Ram P. Kapil, Stephen C. Harris, Salvatore V. Colucci, Alessandra Cipriano, Warren Wen, Ellie He, Shau Yu Lynch

المصدر: Clinical Therapeutics. (2):302-314

مصطلحات موضوعية: Adult, Male, Substance-Related Disorders, Analgesic, effectiveness, Pharmacology, Drug Administration Schedule, hydrocodone, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, 030202 anesthesiology, medicine, Humans, Pharmacology (medical), Longitudinal Studies, Aged, Aged, 80 and over, Cross-Over Studies, business.industry, Chronic pain, analgesia, Middle Aged, medicine.disease, Ibuprofen, Crossover study, Bioavailability, Hydrocodone, Delayed-Action Preparations, Anesthesia, Female, Chronic Pain, Once daily, business, pharmacokinetics, 030217 neurology & neurosurgery, Tablets, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512e1b38aae3c78fbc1c52798980ea34