المؤلفون: D. Randal Kipp, Craig Mickanin, Jeffery A. Porter, Albert Lai, Bing Zheng, Mark Stump, Yan Yan-Neale, John A. Tallarico, Young Shin Cho, Gregory R. Hoffman, Tobias Schmelzle, William R. Sellers, Samuel B. Ho, E. Robert McDonald, Kavitha Venkatesan, Yue Liu, Songping Zhao, Rosalie deBeaumont, Eric Billy, Ying Lin, Francesco Hofmann, Konstantinos J. Mavrakis, Vladimir Capka, Jianjun Yu, Antoine deWeck, Joshua T. McNamara, Emma Lees, Michael R. Schlabach, Hui Gao, Elizabeth R. Sprague, Nicholas Keen, Kristen Hurov, Kenneth Crawford, David A. Ruddy, David N. Ciccone, Guizhi Yang, Fallon Lin, Gregg McAllister, Justin Gu, Raymond Pagliarini, Alberto C. Vitari, Frank Stegmeier, Yingzi Yue, Hong Yin

المصدر: Science. 351:1208-1213

مصطلحات موضوعية: 0301 basic medicine, Multidisciplinary, Methyltransferase, Methionine, Tumor suppressor gene, Protein arginine methyltransferase 5, Purine nucleoside phosphorylase, Biology, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Biochemistry, CDKN2A, Cell culture, 030220 oncology & carcinogenesis, Cancer cell, Cancer research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f90e55c3fe4c3ecfba28cea037cdc9ce
https://doi.org/10.1126/science.aad5944

المؤلفون: Tim Ruckh, Jane Wang, Stanley Wong, Alberto C Vitari, Stephen Morton, Michael Hopkins, Aaron Topol, Eugeni Vaisberg, Manali Dwarakanath, Zach Scott, Gary Tong, Peter Thana, Sally Kwok, Mark Audeh, Nikki Peck, Sarah Sanowar, Alisha Knudson

المصدر: Cancer Immunology Research. 8:B66-B66

مصطلحات موضوعية: Prioritization, Cancer Research, Tumor microenvironment, Liposome, Biodistribution, Cell binding, Tumor targeting, Preferential distribution, Chemistry, Immunology, Cancer research, Tumor immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aab6646f6d44b7768a7b90fe5e7934c3
https://doi.org/10.1158/2326-6074.tumimm18-b66

المؤلفون: Dario R. Alessi, Jacob Thastrup, Maria Deak, Alberto C. Vitari, Fatema H. Rafiqi, Youcef Mehellou, Eulalia Pozo-Guisado

المصدر: Biochemical Journal

مصطلحات موضوعية: HEK-293, human embryonic kidney 293, Biochemistry, 0302 clinical medicine, WNK Lysine-Deficient Protein Kinase 1, OSR, oxidative stress-responsive kinase, GST, glutathione transferase, Protein Isoforms, Solute Carrier Family 12, Member 2, Na+/Cl− co-transporter (NCC), Phosphorylation, 0303 health sciences, DMEM, Dulbecco's modified Eagle's medium, Kinase, Intracellular Signaling Peptides and Proteins, protein kinase, CCT, conserved C-terminal, WNK1, WNK4, LRRK2, leucine-repeat-rich kinase 2, Signal transduction, signal transduction, PI3K, phosphoinositide 3-kinase, Research Article, Na+/K+/2Cl− co-transporter 1 (NKCC1), CATCHtide, cation chloride co-transporter peptide substrate, RM, Sodium-Potassium-Chloride Symporters, SPAK, SPS1-related proline/alanine-rich kinase, Molecular Sequence Data, Protein Serine-Threonine Kinases, Biology, ERK, extracellular-signal-regulated kinase, Minor Histocompatibility Antigens, 03 medical and health sciences, CCD, coiled-coil domain, NCC, Na+/Cl− co-transporter, Humans, Amino Acid Sequence, Protein kinase A, Molecular Biology, Embryonic Stem Cells, 030304 developmental biology, urogenital system, HEK 293 cells, ES, embryonic stem, WNK, with no lysine (K) kinase, Cell Biology, Protein Structure, Tertiary, coiled-coil domain, HEK293 Cells, Gene Expression Regulation, DTT, dithiothreitol, Mutation, NKCC, Na+/K+/2Cl− co-transporter, osmotic stress, MAPK, mitogen-activated protein kinase, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d214b7cc739690322d66483dbf9ed5c
https://doi.org/10.1042/bj20111879

المؤلفون: Ajay Pandita, Suzana S. Couto, Ronald E. Ferrando, Jo-Anne Hongo, Rajesh Vij, Lilian Phu, Wei-Qiang Gao, Dorothy French, Vishva M. Dixit, Ingrid E. Wertz, Karen O'Rourke, Sankar Mohan, Cindy Yee, Kim Newton, Jinfeng Liu, David Arnott, Alberto C. Vitari, Kevin G. Leong

المصدر: Nature. 474:403-406

مصطلحات موضوعية: medicine.medical_specialty, Multidisciplinary, Tumor suppressor gene, fungi, Cancer, Chromoplexy, Biology, medicine.disease, medicine.disease_cause, TMPRSS2, ETV1, Prostate cancer, Endocrinology, Internal medicine, biology.protein, medicine, Cancer research, PTEN, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::10eb7c804e515e9af75a81c08f119ec6
https://doi.org/10.1038/nature10005

المؤلفون: Amal O. Amer, Vishva M. Dixit, Anasuya Sarkar, Kevin J. Tracey, Lieselotte Vande Walle, Mark D. Wewers, Alberto C. Vitari, Thirumala-Devi Kanneganti, Mohamed Lamkanfi

المصدر: The Journal of Immunology. 185:4385-4392

مصطلحات موضوعية: Male, Blotting, Western, Immunology, Caspase 1, NALP3, Enzyme-Linked Immunosorbent Assay, chemical and pharmacologic phenomena, HMGB1, Article, Proinflammatory cytokine, Mice, medicine, Splenocyte, Animals, Immunology and Allergy, Secretion, HMGB1 Protein, Caspase, Inflammation, Mice, Knockout, biology, Macrophages, Inflammasome, Molecular biology, Endotoxemia, Enzyme Activation, Mice, Inbred C57BL, Microscopy, Fluorescence, Salmonella Infections, biology.protein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aacacf838a56e288ee61b53188af9362
https://doi.org/10.4049/jimmunol.1000803

المؤلفون: Alberto C. Vitari, Anna Zagórska, Jérôme Boudeau, Nick A. Morrice, David G. Campbell, Jacob Thastrup, Dario R. Alessi, Alan R. Prescott, Eulalia Pozo-Guisado, Maria Deak, Fatema H. Rafiqi

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: Cell Survival, Recombinant Fusion Proteins, Molecular Sequence Data, Protein Serine-Threonine Kinases, Clathrin, Article, Minor Histocompatibility Antigens, Phosphoserine, 03 medical and health sciences, 0302 clinical medicine, WNK Lysine-Deficient Protein Kinase 1, Osmotic Pressure, Catalytic Domain, Animals, Humans, Sorbitol, Amino Acid Sequence, Phosphorylation, Protein kinase A, Research Articles, 030304 developmental biology, 0303 health sciences, biology, Kinase, Cytoplasmic Vesicles, Intracellular Signaling Peptides and Proteins, Signal transducing adaptor protein, Cell Biology, WNK1, Rats, Cell biology, Transport protein, Enzyme Activation, Protein Transport, biology.protein, 030217 neurology & neurosurgery, Vesicle localization, HeLa Cells, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a586c9fe06cbcd866e8edc98d5ef83a
https://doi.org/10.1083/jcb.200605093

المؤلفون: Maria Deak, Alberto C. Vitari, Dario R. Alessi, Nick A. Morrice

المصدر: Biochemical Journal. 391:17-24

مصطلحات موضوعية: Male, Molecular Sequence Data, Accelerated Publication, Protein Serine-Threonine Kinases, Biology, Biochemistry, Gene Expression Regulation, Enzymologic, Cell Line, Minor Histocompatibility Antigens, Serine, WNK Lysine-Deficient Protein Kinase 1, Testis, Animals, Humans, Amino Acid Sequence, Phosphorylation, Protein kinase A, Molecular Biology, Alanine, Sequence Homology, Amino Acid, urogenital system, Kinase, Syndrome, Cell Biology, WNK1, Rats, WNK4, Enzyme Activation, Hypertension, Mutation, Hyperkalemia, Protein Kinases, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742e3fbf313a4d3ba15954fed9da89af
https://doi.org/10.1042/bj20051180

المؤلفون: Sian Humphreys, Dario R. Alessi, Alberto C. Vitari, Maria Deak, Anne Phelan, Alan R. Prescott, Nick Morrice, Barry Collins

المصدر: Biochemical Journal. 378:257-268

مصطلحات موضوعية: Pseudohypoaldosteronism, AKT1, P70-S6 Kinase 1, Protein Serine-Threonine Kinases, Mitogen-activated protein kinase kinase, Ribosomal Protein S6 Kinases, 90-kDa, Biochemistry, mTORC2, Catalysis, Cell Line, MAP2K7, Minor Histocompatibility Antigens, WNK Lysine-Deficient Protein Kinase 1, Antibody Specificity, Proto-Oncogene Proteins, Humans, Insulin-Like Growth Factor I, Phosphorylation, Molecular Biology, Protein kinase C, biology, Akt/PKB signaling pathway, Cyclin-dependent kinase 2, Intracellular Signaling Peptides and Proteins, Syndrome, Cell Biology, Molecular biology, Phosphothreonine, Hypertension, Mutation, biology.protein, Proto-Oncogene Proteins c-akt, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00bd4cdbc8bc7513883164ba8eb34c2
https://doi.org/10.1042/bj20031692

المؤلفون: Christine Stephan, William R. Sellers, Deborah Castelletti, Jeffery A. Porter, Julie L. Bernard, Sandra Mollé, Mark Stump, Tami Hood, Joshua M. Korn, Audrey Kauffmann, Giorgio G. Galli, Kristine Yu, Li Li, Marc Hattenberger, Javad Golji, Zainab Jagani, Marco Wallroth, Tobias Schmelzle, Philippe Megel, Raymond Pagliarini, Rosemary Barrett, Yingzi Yue, Richard S. Eldridge, Jan Weiler, Alberto C. Vitari, Konstantinos J. Mavrakis, Kalyani Gampa, Elizabeth Ackley, Rosalie deBeaumont, Qiong Shen, Joel Berger, Tanja Schouwey, Franklin Chung, E. Robert McDonald, Gregory McAllister, Christelle Stamm, Frances Shanahan, Aurore Desplat, Iris Kao, Thomas A. Perkins, Antoine de Weck, Kavitha Venkatesan, Albert Lai, Jennifer Johnson, Roland Widmer, David A. Ruddy, Avnish Kapoor, Brian Repko, François Gauter, Nicholas Keen, Tanushree Phadke, Eric Billy, Sosathya Sovath, Typhaine Martin, Elizabeth Frias, Justina X. Caushi, Vic E. Myer, Malini Varadarajan, William C. Forrester, Fei Feng, Hans Bitter, Ralph Tiedt, Yue Liu, Jing Zhang, Dorothee Abramowski, Dhiren Belur, Volker M. Stucke, Odile Weber, Mathias Jenal, Ali Farsidjani, Jianjun Yu, Rebecca Billig, JiaJia Feng, A. B. Meyer, Kristen Hurov, Veronica Gibaja, Michael D. Jones, Daisy Flemming, Donald A. Dwoske, Jilin Liu, Clara Delaunay, William Duong, Frank Buxton, Kaitlin J. Macchi, Saskia M. Brachmann, Alice T. Loo, Craig Mickanin, Francesco Hofmann, Frank Stegmeier, Kristy Haas, Gregory R. Hoffman, Marta Cortes-Cros, Roger Caothien, Shumei Liu, Serena J. Silver, Michael R. Schlabach, Emma Lees, Nadire Ramadan, Qiumei Liu, Zhenhai Gao

المصدر: Cell. 170:577-592.e10

مصطلحات موضوعية: 0301 basic medicine, Lineage (genetic), Tumor suppressor gene, Mutant, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, RNA interference, Cell Line, Tumor, Neoplasms, medicine, Humans, Gene Regulatory Networks, RNA, Small Interfering, Gene, Gene Library, Genetics, Gene knockdown, Cancer, Translation (biology), Oncogenes, medicine.disease, 030104 developmental biology, Multiprotein Complexes, RNA Interference, Signal Transduction, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22974eb72276d42f1aa26407b00798f0
https://doi.org/10.1016/j.cell.2017.07.005

المؤلفون: Alberto C. Vitari, Nick A. Morrice, Jacob Thastrup, Håkan K. R. Karlsson, Maria Deak, Fatema H. Rafiqi, Dario R. Alessi

المصدر: The Biochemical journal. 397(1)

مصطلحات موضوعية: Threonine, Sodium-Potassium-Chloride Symporters, Peptide, Biology, Protein Serine-Threonine Kinases, Kidney, Biochemistry, Substrate Specificity, Minor Histocompatibility Antigens, WNK Lysine-Deficient Protein Kinase 1, Serine, Humans, Solute Carrier Family 12, Member 2, Phosphorylation, Protein kinase A, Molecular Biology, Cells, Cultured, Alanine, chemistry.chemical_classification, Binding Sites, Sequence Homology, Amino Acid, Kinase, Activator (genetics), Osmolar Concentration, Intracellular Signaling Peptides and Proteins, Cell Biology, WNK1, WNK4, Enzyme Activation, chemistry, Hypertension, Mutation, Hyperkalemia, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0a7ee5fffda03041c850befab25292
https://pubmed.ncbi.nlm.nih.gov/16669787

المؤلفون: Jacob O. Thastrup, Fatema H. Rafiqi, Alberto C. Vitari, Eulalia Pozo-guisado, Maria Deak, Youcef Mehellou

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/00/e8/Biochem_J_2012_Jan_1_441(Pt_1)_325-337.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.286.8657

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.286.8657

المؤلفون: Anna Zagórska, Eulalia Pozo-guisado, Jérôme Boudeau, Alberto C. Vitari, Fatema H. Rafiqi, Jacob Thastrup, Maria Deak, David G. Campbell, Nick A. Morrice, Alan R. Prescott, Dario R. Alessi, Mutations Within The Wnk (with-no-k lys

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/68/25/J_Cell_Biol_2007_Jan_1_176(1)_89-100.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.283.8979

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.283.8979

المؤلفون: Wyne P. Lee, Kurt Deshayes, Vishva M. Dixit, James L. Mueller, Alberto C. Vitari, Mohamed Lamkanfi, Anna V. Fedorova, Shahram Misaghi, Hal M. Hoffman

المصدر: JOURNAL OF CELL BIOLOGY
The Journal of Cell Biology

مصطلحات موضوعية: Lipopolysaccharides, Male, Salmonella typhimurium, Damp, Interleukin-1beta, NALP3, Pharmacology, MOUSE, Monocytes, Pathogenesis, Mice, Random Allocation, Adenosine Triphosphate, INTERLEUKIN-1-BETA RELEASE, BINDING CASSETTE TRANSPORTER, Glyburide, Immunology and Allergy, Cells, Cultured, Research Articles, Adenosine Triphosphatases, Mice, Knockout, Mice, Inbred BALB C, integumentary system, Caspase 1, COLD AUTOINFLAMMATORY SYNDROME, Interleukin-18, P2X(7) RECEPTOR, Inflammasome, NALP3 INFLAMMASOME, medicine.drug, Immunology, Biology, INSULIN-SECRETION, Report, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Animals, Humans, Hypoglycemic Agents, ATP BINDING, Secretion, Gouty arthritis, CASPASE-1, Inflammation, Adenosine triphosphatase, Macrophages, Biology and Life Sciences, SULFONYLUREA RECEPTOR, Transporter, Cell Biology, Enzyme Activation, Mice, Inbred C57BL, Mutation, biology.protein, Carrier Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0df87bd7334b8b65fb8e59a56f74676
https://doi.org/10.1084/jem20611oia25

المؤلفون: Jacob O. Thastrup, Fatema H. Rafiqi, Alberto C. Vitari, Eulalia Pozo‑Guisado, Maria Deak, Youcef Mehellou, Dario R. Alessi

المصدر: Biochemical Journal; Jan2012, Vol. 441 Issue 1, p325-337, 13p

مصطلحات موضوعية: AUTOPHOSPHORYLATION, GENETIC mutation, LYSINE, PROTEIN kinases, HYPERTENSION, PAIN perception, PHOSPHORYLATION, CELLULAR signal transduction, CELL communication