المؤلفون: Alan F Hofmann

المصدر: Annals of Hepatology, Vol 6, Iss 1, Pp 15-27 (2007)

مصطلحات موضوعية: Bile acids, bile salts, bile acid metabolism, bile acid transport, biliary disease, Specialties of internal medicine, RC581-951

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268119319490; https://doaj.org/toc/1665-2681

URL الوصول: https://doaj.org/article/112ba7a69ef74a92a26d069d98133a32

المؤلفون: Alan F. Hofmann, MD

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 201-202 (2020)

مصطلحات موضوعية: Diseases of the digestive system. Gastroenterology, RC799-869

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X20300400; https://doaj.org/toc/2352-345X; https://doaj.org/article/95de6fc7a43c44698ef8252d2598063b

الاتاحة: https://doi.org/10.1016/j.jcmgh.2020.03.004
https://doaj.org/article/95de6fc7a43c44698ef8252d2598063b

المؤلفون: Alan F. Hofmann, Lee R. Hagey

المصدر: Journal of Lipid Research, Vol 55, Iss 8, Pp 1553-1595 (2014)

مصطلحات موضوعية: bile acid transport, enterohepatic circulation, bile acid physical chemistry, bile acid analysis, bile acid metabolism, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520353232; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/71574a5f9f2d477290ec5736da47ae67

المؤلفون: Alan F. Hofmann, Mary Erickson, Kristoffer Kjærgaard, Susanne Keiding, David Shapiro, Michael Sørensen, Anna C. Schacht, Ole Lajord Munk, Jacob Horsager, Kim Frisch

المصدر: Kjærgaard, K, Frisch, K, Sørensen, M, Munk, O L, Hofmann, A F, Horsager, J, Schacht, A C, Erickson, M, Shapiro, D A & Keiding, S 2021, ' Obeticholic acid improves hepatic bile acid excretion in patients with primary biliary cholangitis ', Journal of Hepatology, vol. 74, no. 1, pp. 58-65 . https://doi.org/10.1016/j.jhep.2020.07.028

مصطلحات موضوعية: 0301 basic medicine, INDOCYANINE GREEN, Receptors, Cytoplasmic and Nuclear, Chronic liver disease, Gastroenterology, chemistry.chemical_compound, 0302 clinical medicine, CIRRHOSIS, GENE-EXPRESSION, Bile acid, Liver Cirrhosis, Biliary, Ursodeoxycholic Acid, Intrahepatic cholestasis, Obeticholic acid, Middle Aged, G protein-coupled bile acid receptor, Ursodeoxycholic acid, Treatment Outcome, FXR, HEPATOBILIARY SECRETION, CHOLYLSARCOSINE, Alkaline phosphatase, Female, 030211 gastroenterology & hepatology, FARNESOID-X-RECEPTOR, medicine.drug, medicine.medical_specialty, medicine.drug_class, Bile acid-binding proteins, Molecular imaging, Chenodeoxycholic Acid, digestive system, Bile Acids and Salts, Excretion, 03 medical and health sciences, Farnesoid X receptor, Double-Blind Method, Gastrointestinal Agents, Internal medicine, medicine, Humans, KINETICS, Aged, Hepatology, business.industry, Biological Transport, Alkaline Phosphatase, medicine.disease, URSODEOXYCHOLIC ACID, SALT EXPORT PUMP, Bile Ducts, Intrahepatic, 030104 developmental biology, chemistry, Positron-Emission Tomography, Liver cirrhosis, Hepatocytes, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8852637514a0cfe3f5190f789668a8c
https://doi.org/10.1016/j.jhep.2020.07.028

المؤلفون: Genta Kakiyama, Hideyuki Tamegai, Takashi Iida, Kuniko Mitamura, Shigeo Ikegawa, Takaaki Goto, Nariyasu Mano, Junichi Goto, Peter Holz, Lee R. Hagey, Alan F. Hofmann

المصدر: Journal of Lipid Research, Vol 48, Iss 12, Pp 2682-2692 (2007)

مصطلحات موضوعية: bile acid synthesis, detoxification of bile acids, bile acid metabolism in marsupials, 15-hydroxylation, lithocholic acid, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520429190; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/3958941c4b8d4677a6ad615348334063

المؤلفون: Ephraim Sehayek, Lee R. Hagey, Yee-Yan Fung, Elizabeth M. Duncan, Hannah J. Yu, Gösta Eggertsen, Ingemar Björkhem, Alan F. Hofmann, Jan L. Breslow

المصدر: Journal of Lipid Research, Vol 47, Iss 9, Pp 2020-2027 (2006)

مصطلحات موضوعية: chenodeoxycholic acid, sterol 12α-hydroxylase, cholic acid, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520434698; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/d1aa8ae5867a44ae853af8cdf3ad74eb

المؤلفون: Lee R. Hagey, Claudio D. Schteingart, Steven S. Rossi, H-T. Ton-Nu, Alan F. Hofmann

المصدر: Journal of Lipid Research, Vol 39, Iss 11, Pp 2119-2124 (1998)

مصطلحات موضوعية: bile acid metabolism, lithocholic acid, chenodeoxycholic acid metabolism, enterohepatic circulation, bile acid conjugation, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520324664; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/eb280d5042844dc1af61d7fbdf58da85

المؤلفون: Genta Kakiyama, Akina Muto, Hajime Takei, Hiroshi Nittono, Tsuyoshi Murai, Takao Kurosawa, Alan F. Hofmann, William M. Pandak, Jasmohan S. Bajaj

المصدر: Journal of Lipid Research, Vol 55, Iss 5, Pp 978-990 (2014)

مصطلحات موضوعية: extraction, esterified bile acids, bile acid 24-phenacyl ester, derivatization, liver cirrhosis, high-performance liquid chromatography, Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520375167; https://doaj.org/toc/0022-2275; https://doaj.org/article/26bdfabe4bd34b26b0e99fed0a23855f

الاتاحة: https://doi.org/10.1194/jlr.D047506
https://doaj.org/article/26bdfabe4bd34b26b0e99fed0a23855f

المؤلفون: Kim Frisch, Susanne Keiding, Alan F. Hofmann

المصدر: Keiding, S, Frisch, K & Hofmann, A F 2021, ' Reply to: "Obeticholic acid and hepatic bile acids: Excellent study faulty conclusion" ', Journal of Hepatology, vol. 74, no. 5, pp. 1268-1269 . https://doi.org/10.1016/j.jhep.2021.02.014

مصطلحات موضوعية: Bile Acids and Salts, chemistry.chemical_compound, medicine.medical_specialty, Hepatology, chemistry, Liver, Internal medicine, medicine, Obeticholic acid, Chenodeoxycholic Acid, Hepatic bile, Gastroenterology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c19c4e14319b58870ac846e22d2caf
https://pubmed.ncbi.nlm.nih.gov/33508377

المؤلفون: Lee R. Hagey, Genta Kakiyama, Akina Muto, Takashi Iida, Kumiko Mushiake, Takaaki Goto, Nariyasu Mano, Junichi Goto, Cleida A. Oliveira, Alan F. Hofmann

المصدر: Journal of Lipid Research, Vol 50, Iss 4, Pp 651-657 (2009)

مصطلحات موضوعية: 1β-hydroxylation, C27 bile acids, 1β,3α,7α-trihydroxy-5β-cholestan-27-oic acid, taurine conjugate, LC-MS, NMR, Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520308622; https://doaj.org/toc/0022-2275; https://doaj.org/article/fadaeaf39e6f48db83e005db9b4df3bd

الاتاحة: https://doi.org/10.1194/jlr.M800521-JLR200
https://doaj.org/article/fadaeaf39e6f48db83e005db9b4df3bd

المؤلفون: Erica J. Reschly, Ni Ai, Sean Ekins, William J. Welsh, Lee R. Hagey, Alan F. Hofmann, Matthew D. Krasowski

المصدر: Journal of Lipid Research, Vol 49, Iss 7, Pp 1577-1587 (2008)

مصطلحات موضوعية: fishes, lampreys, lithocholic acid, molecular evolution, molecular models, nuclear hormone receptors, Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520347295; https://doaj.org/toc/0022-2275; https://doaj.org/article/75d08107df4b49baaeb229ee45e57336

الاتاحة: https://doi.org/10.1194/jlr.M800138-JLR200
https://doaj.org/article/75d08107df4b49baaeb229ee45e57336

المؤلفون: Genta Kakiyama, Takashi Iida, Takaaki Goto, Nariyasu Mano, Junichi Goto, Toshio Nambara, Lee R. Hagey, Claudio D. Schteingart, Alan F. Hofmann

المصدر: Journal of Lipid Research, Vol 47, Iss 7, Pp 1551-1558 (2006)

مصطلحات موضوعية: Anseriformes, bile acid evolution, bile acid conjugation, Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520332004; https://doaj.org/toc/0022-2275; https://doaj.org/article/083b75ed80bd4d7ebdd727dbd4753eab

الاتاحة: https://doi.org/10.1194/jlr.M600149-JLR200
https://doaj.org/article/083b75ed80bd4d7ebdd727dbd4753eab

المؤلفون: Antonio Moschetta, Fang Xu, Lee R. Hagey, Gerard P. van Berge-Henegouwen, Karel J. van Erpecum, Jos F. Brouwers, Jonathan C. Cohen, Molly Bierman, Helen H. Hobbs, Joseph H. Steinbach, Alan F. Hofmann

المصدر: Journal of Lipid Research, Vol 46, Iss 10, Pp 2221-2232 (2005)

مصطلحات موضوعية: bile salts, cholesterol, gas chromatography, mass spectrometry, phosphatidylcholine, sphingomyelin, Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520329138; https://doaj.org/toc/0022-2275; https://doaj.org/article/9632bad0da344203aa3682930e347105

الاتاحة: https://doi.org/10.1194/jlr.M500178-JLR200
https://doaj.org/article/9632bad0da344203aa3682930e347105

المؤلفون: Genta Kakiyama, Takashi Iida, Atsushi Yoshimoto, Takaaki Goto, Nariyasu Mano, Junichi Goto, Toshio Nambara, Lee R. Hagey, Alan F. Hofmann

المصدر: Journal of Lipid Research, Vol 45, Iss 3, Pp 567-573 (2004)

مصطلحات موضوعية: unsaturated bile acid, tauro-Δ22-β-muricholic acid, Δ22-β-muricholyltaurine, glyco-Δ22-β-muricholic acid, Δ22-β-muricholylglycine, Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S002222752031885X; https://doaj.org/toc/0022-2275; https://doaj.org/article/b764bad6d4744d4fb87acd5b24ab17ef

الاتاحة: https://doi.org/10.1194/jlr.D300027-JLR200
https://doaj.org/article/b764bad6d4744d4fb87acd5b24ab17ef

المؤلفون: Alan F. Hofmann

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.uib.no/med/avd/miapr/arvid/GI/NIPS_1999_14_24.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.323.1620; http://www.uib.no/med/avd/miapr/arvid/GI/NIPS_1999_14_24.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.323.1620
http://www.uib.no/med/avd/miapr/arvid/GI/NIPS_1999_14_24.pdf

المؤلفون: Takashi Iida, Kuniko Mitamura, Tetsuya Saito, Kaoru Omura, Shigeo Ikegawa, Lee R. Hagey, Alan F. Hofmann, Hiroaki Ogata, Rika Satoh, Biao Zhou, Satoshi Kurabuchi

المصدر: Lipids. 51:757-768

مصطلحات موضوعية: 0301 basic medicine, Taurine, Buceros, medicine.drug_class, Stereochemistry, Hornbill, Crystallography, X-Ray, Biochemistry, Bile Acids and Salts, Birds, 03 medical and health sciences, chemistry.chemical_compound, Penelopides panini, medicine, Animals, Chromatography, High Pressure Liquid, Molecular Structure, Bile acid, biology, Organic Chemistry, Diastereomer, Gallbladder, Stereoisomerism, Cell Biology, biology.organism_classification, Great hornbill, 030104 developmental biology, chemistry, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f642f611bf6b82287a15e4e4a3f21f3
https://doi.org/10.1007/s11745-016-4150-0

المؤلفون: Aya A. Abbas, Alan F. Hofmann, Reham Hassan, Ute Hofmann, Selahaddin Sezgin, Peter L.M. Jansen, Patricio Godoy, Nachiket Vartak, Frank Lammert, Steven Dooley, Jan G. Hengstler, Dirk Drasdo, Kai Markus Schneider, Christian Trautwein, Yasser A. Ahmed, Michael Spiteller, Raymond Reif, Lars Kuepfer, Verena Keitel, Georgia Guenther, Ahmed Ghallab, A Zaza

المساهمون: Department of Forensic Medicine and Veterinary Toxicology [Qena], Faculty of Veterinary Medicine [Qena], South Valley University [Qena]-South Valley University [Qena], Dr. Margarete Fischer-Bosch Institute for Clinical Pharmacology [Stuttgart], Technische Universität Dortmund [Dortmund] (TU), Leibniz Research Centre for Working Environment and Human Factors [Dortmund] (IFADO), Rheinisch-Westfälische Technische Hochschule Aachen (RWTH), South Valley University [Qena], Heinrich Heine Universität Düsseldorf = Heinrich Heine University [Düsseldorf], Computational Systems Biology [Leverkusen], Bayer Technology Services [Leverkusen], Universität Mannheim [Mannheim], Saarland University [Saarbrücken], Modelling and Analysis for Medical and Biological Applications (MAMBA), Inria de Paris, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire Jacques-Louis Lions (LJLL (UMR_7598)), Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), University of California [San Diego] (UC San Diego), University of California, Maastricht University [Maastricht], RS: FSE MaCSBio, Maastricht Centre for Systems Biology, RS: FHML MaCSBio, RS: FPN MaCSBio, Heinrich-Heine-Universität Düsseldorf [Düsseldorf], Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), Universität Mannheim, Universitätsklinikum RWTH Aachen - University Hospital Aachen [Aachen, Germany] (UKA), University of California (UC)

المصدر: Hepatology
Hepatology, Wiley-Blackwell, 2018, ⟨10.1002/hep.30213⟩
Hepatology, 69(2), 666-683. Wiley
Hepatology : official journal of the American Association for the Study of Liver Diseases 69(2), 666-683 (2018). doi:10.1002/hep.30213
Hepatology, Wiley-Blackwell, 2018
Hepatology, 2019, 69 (2), pp.666-683. ⟨10.1002/hep.30213⟩

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, medicine.medical_specialty, Necrosis, ATP Binding Cassette Transporter, Subfamily B, mice, injury, [SDV]Life Sciences [q-bio], Bone canaliculus, digestive system, Nephropathy, Bile Acids and Salts, 03 medical and health sciences, 0302 clinical medicine, Cholestasis, INFLAMMATION, medicine, Animals, Mice, Knockout, Kidney, Hepatology, cholemic nephropathy, RAT HEPATOCYTES, Chemistry, Bile Canaliculi, Optical Imaging, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, ACIDS, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation, TRANSPORT, 3. Good health, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Biliary tract, Hepatocyte, [INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV], Hepatocytes, 030211 gastroenterology & hepatology, medicine.symptom, Immunostaining

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a2e52c1c2e73ca4a1e78ec2e654d26
https://hal.inria.fr/hal-01968843

المؤلفون: Alan F. HOFMANN, Kuniko MITAMURA, Masako MAEDA, Rika OKIHARA, Rung-Hwa CHONG, Shigeo IKEGAWA, Shunji ISHIWATA, Takahiro MIYASHITA, Tetsushi YAMAMOTO, Toshihiro SAKAI

المصدر: Analytical Sciences. 2008, 24(11):1475

المؤلفون: Kyoko Iida, Takashi Iida, Alan F. Hofmann, Kaoru Omura, Kazunari Namegawa, Naoya Nakane

المصدر: CHEMICAL & PHARMACEUTICAL BULLETIN. 64:1397-1402

مصطلحات موضوعية: 0301 basic medicine, Biological Products, Lithocholic acid, Chemistry, Decarbonylation, Sodium chlorite, Deoxycholic acid, Markovnikov's rule, Molecular Conformation, Cholic acid, General Chemistry, General Medicine, Chenodeoxycholic Acid, Chemical synthesis, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Chenodeoxycholic acid, Drug Discovery, Organic chemistry, Lithocholic Acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670472e45d4ee5df3c91c8208ac87485
https://doi.org/10.1248/cpb.c16-00247

المؤلفون: Alan F. Hofmann, Péter Hegyi, József Maléth, Stephen J. Keely, Julian R.F. Walters

مصطلحات موضوعية: 0301 basic medicine, Gastrointestinal Diseases, Physiology, Disease, Biology, Microbiology, Bile Acids and Salts, 03 medical and health sciences, 0302 clinical medicine, Accessory organs, Physiology (medical), Gall, Animals, Humans, Intestinal Mucosa, Molecular Biology, chemistry.chemical_classification, Gastrointestinal tract, Epithelial Cells, General Medicine, 11 Medical And Health Sciences, 06 Biological Sciences, Intestines, 030104 developmental biology, Enzyme, chemistry, 030211 gastroenterology & hepatology, Medical science, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b1c6fadc4b8703560b9c45f84092fd
http://hdl.handle.net/10044/1/61875