المؤلفون: Akio IMANISHI, Hideki FURUKAWA, Hiroshi KOHARA, Koki NISHIMURA, Kosuke HARADA, Tadahiro SHINOZAWA, Yoshiko OKAI, Yuta ARAI, Yuuhei YAMAMOTO, 今西 章夫, 原田 幸祐, 古川 英紀, 小原 洋志, 山本 裕平, 岡井 佳子, 新井 勇太, 篠澤 忠紘, 西村 公樹

المصدر: Annual Meeting of the Japanese Society of Toxicology. 2022, :P-104

المؤلفون: Kosuke Harada, Hideki Furukawa, Hiroshi Kohara, Koki Nishimura, Hisakazu Komori, Yoshiko Okai, Yuta Arai, Yuhei Yamamoto, Katsuhiko Yamamoto, Akio Imanishi, Tadahiro Shinozawa

المصدر: Toxicology in Vitro. 89:105569

مصطلحات موضوعية: General Medicine, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d52d2db2b63de828d06b77d8209def57
https://doi.org/10.1016/j.tiv.2023.105569

المؤلفون: Masako Kuno, Yuya Nishiyama, Akio Imanishi, Hiroshi Nagata, Takuya Kato, Izumi Kamo, Satoshi Okanishi, Kyoko Yoshikawa, Gale O'Connell

المصدر: Journal of Pharmacology and Experimental Therapeutics. 378:60-68

مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Urinary Bladder, Stimulation, chemistry.chemical_compound, Internal medicine, Receptor, Serotonin, 5-HT2C, medicine, Animals, Humans, Pharmacology, business.industry, Urethral sphincter, Receptor antagonist, Rats, Transcranial magnetic stimulation, Urethra, medicine.anatomical_structure, Endocrinology, chemistry, Reflex, Molecular Medicine, Female, business, SB-242084

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0c4500cd14bcf3cdeb2f1d63adc193
https://doi.org/10.1124/jpet.121.000573

المؤلفون: Takahiro Tanaka, Shiho Matsumoto-Okano, Nobuhiro Inatomi, Yasushi Fujioka, Hidenori Kamiguchi, Masashi Yamaguchi, Akio Imanishi, Makiko Kawamoto, Kasei Miura, Yoichi Nishikawa, Yasuhiro Tsukimi

المصدر: Journal of Pharmacological Sciences, Vol 118, Iss 4, Pp 487-495 (2012)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861319305420; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/0806af0bcee4466e990863cb54999d4d

المؤلفون: Takahiro Tanaka, Akiko Tanaka, Akihiro Nakamura, Kozo Matsushita, Akio Imanishi, Shiho Matsumoto-Okano, Nobuhiro Inatomi, Kasei Miura, Masao Toyoda, Gaku Mizojiri, Yasuhiro Tsukimi

المصدر: Journal of Pharmacological Sciences, Vol 120, Iss 1, Pp 15-25 (2012)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861319304608; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/7f7e33b0302a467eb8190607814504fa

المؤلفون: Akihiro Nakamura, Takahiro Tanaka, Akio Imanishi, Makiko Kawamoto, Masao Toyoda, Gaku Mizojiri, Yasuhiro Tsukimi

المصدر: Journal of Pharmacological Sciences, Vol 117, Iss 2, Pp 106-115 (2011)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861319306425; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/f5dd34c6cb6141b9bfda170ef9aec27a

المؤلفون: Akio Imanishi, Masanori Kawasaki, Tatsuki Koike, Takamitsu Maru, Atsushi Suzuki, Tohru Miyazaki, Tomohiro Kawamoto, Yuki Ito

المصدر: Bioorganic & Medicinal Chemistry Letters. 29:815-820

مصطلحات موضوعية: Nicotinamide, 010405 organic chemistry, Activator (genetics), Sodium channel, Organic Chemistry, Clinical Biochemistry, Central nervous system, Pharmaceutical Science, medicine.disease, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Dravet syndrome, Drug Discovery, NAV1, medicine, Molecular Medicine, Isoxazole, Selectivity, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::97b7ab54b1f201a12abb5a8c3a0ba881
https://doi.org/10.1016/j.bmcl.2019.01.023

المؤلفون: Tomoya Yukawa, Akio Imanishi, Piyush Bajaj, Matthew Wagoner, Colin D. Brown, Yuichi Takai, Keith Pye, Git Chung

المصدر: Toxicology. 442

مصطلحات موضوعية: 0301 basic medicine, Organic anion transporter 1, Endpoint Determination, Primary Cell Culture, Gene Expression, Lipocalin, Pharmacology, Toxicology, Nephrotoxicity, Kidney Tubules, Proximal, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Kidney, Clusterin, biology, Chemistry, Organic Cation Transporter 2, Reproducibility of Results, Transporter, Cubilin, Fanconi Syndrome, 030104 developmental biology, medicine.anatomical_structure, Toxicity, biology.protein, 030217 neurology & neurosurgery, Biomarkers, Octamer Transcription Factor-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad590fbf5d11c46ab0567a75c2e13412
https://pubmed.ncbi.nlm.nih.gov/32622972

المؤلفون: Yasunobu Hori, Akio Imanishi, Naoki Tarui, Yasushi Fujioka, Toshihiro Imaeda, Fumio Itoh, Mitsuyo Kondo, Haruyuki Nishida, Koji Ono, Masahiro Kajino, Kazuo Nakai, Nobuhiro Inatomi, Jun Matsukawa, Terufumi Takagi

المصدر: Bioorganic & Medicinal Chemistry. 25:3719-3735

مصطلحات موضوعية: 0301 basic medicine, Drug, Stereochemistry, Potassium, media_common.quotation_subject, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, chemistry.chemical_element, Naphthalenes, Inhibitory postsynaptic potential, Biochemistry, Gastric Acid, H(+)-K(+)-Exchanging ATPase, Inhibitory Concentration 50, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, Drug Discovery, medicine, Animals, Spiro Compounds, Secretion, Molecular Biology, media_common, Naphthalene, Binding Sites, Stomach, Organic Chemistry, Proton Pump Inhibitors, Rats, Molecular Docking Simulation, 030104 developmental biology, medicine.anatomical_structure, ROC Curve, chemistry, Gastric Mucosa, Docking (molecular), Area Under Curve, 030220 oncology & carcinogenesis, Molecular Medicine, Gastric acid, Administration, Intravenous, Half-Life, Histamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24660c0fa82967a04b22a0fe1f9f9a0
https://doi.org/10.1016/j.bmc.2017.05.012

المؤلفون: Tohru, Miyazaki, Masanori, Kawasaki, Atsushi, Suzuki, Yuki, Ito, Akio, Imanishi, Takamitsu, Maru, Tomohiro, Kawamoto, Tatsuki, Koike

المصدر: Bioorganicmedicinal chemistry letters. 29(6)

مصطلحات موضوعية: NAV1.1 Voltage-Gated Sodium Channel, Niacinamide, Mice, Structure-Activity Relationship, Cricetulus, Pyrrolidines, Molecular Structure, Blood-Brain Barrier, Drug Discovery, Animals, CHO Cells, Voltage-Gated Sodium Channel Agonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c3d4fcb7bd1b0748ac655517fb3b2e6d
https://pubmed.ncbi.nlm.nih.gov/30704812

المؤلفون: AKIO IMANISHI, HIROYUKI KOBAYASHI, KENJI SATO, MAKOTO OHTA, MASAYUKI WATANABE, RYUZO HIRATA, TAKASHI ANDO, TOMOKO KAJISA, TOMOMI SHIMIZU, YOSHIO SUZUKI, 今西 昭雄, 佐藤 健司, 加治 佐知子, 太田 眞, 安藤 隆, 小林 弘幸, 平田 龍三, 清水 智美, 渡辺 雅之, 鈴木 良雄

المصدر: 順天堂医学 / Juntendo Medical Journal. 2012, 58(2):161

المؤلفون: Keishoku Sakuraba, Masayuki Watanabe, Yoshio Suzuki, Tomomi Shimizu, Makoto Ota, Yoshifumi Tamura, Kenji Sato, Akio Imanishi, Ryuzo Hirata

المصدر: Experimental and Therapeutic Medicine. 10:978-982

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, biology, Athletes, business.industry, Insulin, medicine.medical_treatment, Articles, General Medicine, Carbohydrate, biology.organism_classification, Endocrinology, Immunology and Microbiology (miscellaneous), Endurance training, Internal medicine, Medicine, Ingestion, Glucose kinetics, business, Self paced, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338e9b26d0b30a922fddcc10a30f8bac
https://doi.org/10.3892/etm.2015.2587

المؤلفون: Hideo Fukui, Ikuo Fujimori, Nobuhiro Inatomi, Koji Ono, Keizo Hirase, Haruyuki Nishida, Akio Imanishi, Yasuyoshi Arikawa, Fumio Itoh, Yasunobu Hori, Jun Matsukawa, Kazuo Nakai, Yasushi Fujioka

المصدر: Bioorganicmedicinal chemistry. 25(13)

مصطلحات موضوعية: Drug, Male, Stereochemistry, Potassium, media_common.quotation_subject, Clinical Biochemistry, Pharmaceutical Science, chemistry.chemical_element, Administration, Oral, Ring (chemistry), 01 natural sciences, Biochemistry, Gastric Acid, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, H(+)-K(+)-Exchanging ATPase, Structure-Activity Relationship, 0302 clinical medicine, Drug Discovery, Animals, Humans, Pyrroles, Molecular Biology, Pyrrole, media_common, Sulfonyl, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Proton Pump Inhibitors, Combinatorial chemistry, 0104 chemical sciences, Rats, chemistry, Molecular Medicine, Gastric acid, 030211 gastroenterology & hepatology, Lead compound, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc7a1db9c3bce976c446c8b740f5b32
https://pubmed.ncbi.nlm.nih.gov/28483454

المؤلفون: Yasuyoshi Arikawa, Yasushi Fujioka, Motoo Iida, Mitsuyoshi Nishitani, Jun Matsukawa, Toshihiro Imaeda, Teruki Hamada, Yasunobu Hori, Fumio Itoh, Keizo Hirase, Nobuhiro Inatomi, Akio Imanishi, Haruyuki Nishida, Hideo Fukui, Masahiro Kajino

المصدر: Bioorganicmedicinal chemistry. 25(13)

مصطلحات موضوعية: 0301 basic medicine, Drug, Stereochemistry, Cell Survival, media_common.quotation_subject, Potassium, Clinical Biochemistry, Lansoprazole, Pharmaceutical Science, chemistry.chemical_element, Administration, Oral, Biochemistry, PH elevation, Gastric Acid, 03 medical and health sciences, chemistry.chemical_compound, H(+)-K(+)-Exchanging ATPase, Structure-Activity Relationship, Dogs, Drug Discovery, medicine, Animals, Humans, Pyrroles, Molecular Biology, Pyrrole, media_common, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Proton Pump Inhibitors, Hep G2 Cells, Hydrogen-Ion Concentration, Combinatorial chemistry, Ether-A-Go-Go Potassium Channels, Rats, 030104 developmental biology, HEK293 Cells, chemistry, Lipophilicity, Molecular Medicine, Lead compound, Derivative (chemistry), medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bac684f5eccfc18c3228e16d7323bb0
https://pubmed.ncbi.nlm.nih.gov/28442261

المؤلفون: Mitsuyo Kondo, Haruyuki Nishida, Akio Imanishi, Naoki Tarui, Osamu Kurasawa, Masahiro Kajino, Atsushi Hasuoka, Terufumi Takagi, Yasunobu Hori, Nobuhiro Inatomi, Yasuyoshi Arikawa, Fumihiko Sato, Keizo Hirase

المصدر: Bioorganic & Medicinal Chemistry. 20:3925-3938

مصطلحات موضوعية: Male, Models, Molecular, Swine, Stereochemistry, Potassium, Clinical Biochemistry, Pharmaceutical Science, chemistry.chemical_element, Inhibitory postsynaptic potential, Biochemistry, Pyrrole derivatives, Rats, Sprague-Dawley, H(+)-K(+)-Exchanging ATPase, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Drug Discovery, Animals, Structure–activity relationship, Pyrroles, Secretion, Molecular Biology, Pyrrole, Molecular Structure, Drug discovery, Stomach, Organic Chemistry, Proton Pump Inhibitors, Rats, chemistry, Molecular Medicine, Gastric acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11ebe86ca05c17801e0975dc7cca300
https://doi.org/10.1016/j.bmc.2012.04.014

المؤلفون: Atsushi Hasuoka, Mitsuyo Kondo, Haruyuki Nishida, Yasuyoshi Arikawa, Terufumi Takagi, Akio Imanishi, Nobuhiro Inatomi, Osamu Kurasawa, Yasunobu Hori, Keizo Hirase, Masahiro Kajino, Naoki Tarui, Teruki Hamada, Jun Matsukawa, Toshiyuki Takeuchi

المصدر: Journal of Medicinal Chemistry. 55:4446-4456

مصطلحات موضوعية: Male, Peptic Ulcer, Magnetic Resonance Spectroscopy, Stereochemistry, Potassium, chemistry.chemical_element, Pyrrole derivatives, Rats, Sprague-Dawley, H(+)-K(+)-Exchanging ATPase, Inhibitory Concentration 50, Structure-Activity Relationship, Dogs, Fumarates, In vivo, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Pyrroles, Enzyme Inhibitors, Sulfonamides, Molecular Structure, Chemistry, Drug candidate, Proton Pump Inhibitors, Nuclear magnetic resonance spectroscopy, Anti-Ulcer Agents, medicine.disease, Rats, Gastric Mucosa, Peptic ulcer, Molecular Medicine, Gastric acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11eb3b6a9b221556449e78c91290c08b
https://doi.org/10.1021/jm300318t

المؤلفون: Naoki Tarui, Junya Shirai, Tadatoshi Hashimoto, Nobuhiro Inatomi, Shinji Morimoto, Keiko Ishigami, Makiko Kawamoto, Satoshi Okanishi, Akio Imanishi, Hironobu Maezaki, Hideyuki Sugiyama, Izumi Kamo, Shiho Matsumoto, Yasuharu Yamamoto, Yoshinori Ikeura

المصدر: Bioorganic & Medicinal Chemistry. 20:962-977

مصطلحات موضوعية: Receptors, Steroid, Phenylpiperidine, CYP3A, Guinea Pigs, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Motor Activity, Pharmacology, Biochemistry, chemistry.chemical_compound, Neurokinin-1 Receptor Antagonists, Piperidines, Pharmacokinetics, Oral administration, Microsomes, Drug Discovery, Animals, Cytochrome P-450 CYP3A, Humans, Molecular Biology, Pregnane X receptor, Organic Chemistry, Pregnane X Receptor, Stereoisomerism, Receptors, Neurokinin-1, Metabolic stability, Amides, Enzyme Activation, Long acting, chemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9810fd4c6a4c354796c1b6a3db62b0
https://doi.org/10.1016/j.bmc.2011.11.048

المؤلفون: Makiko Kawamoto, Yasuhiro Tsukimi, Takahiro Tanaka, Nishikawa Yoichi, Kasei Miura, Hidenori Kamiguchi, Nobuhiro Inatomi, Akio Imanishi, Masashi Yamaguchi, Shiho Matsumoto-Okano, Yasushi Fujioka

المصدر: Journal of Pharmacological Sciences, Vol 118, Iss 4, Pp 487-495 (2012)

مصطلحات موضوعية: Agonist, Male, medicine.drug_class, Colon, Drug Evaluation, Preclinical, Pharmacology, Intracolonic, Pharmacokinetics, Piperidines, In vivo, medicine, Animals, Receptor, Dose-Response Relationship, Drug, business.industry, lcsh:RM1-950, Receptors, Neurokinin-2, In vitro, Dose–response relationship, lcsh:Therapeutics. Pharmacology, Pharmacodynamics, Benzamides, Models, Animal, Molecular Medicine, Rabbits, business, Muscle Contraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb98591b31982ddc1e4fa444a1ef60dd
http://www.sciencedirect.com/science/article/pii/S1347861319305420

المؤلفون: Makiko Kawamoto, Yasuyoshi Arikawa, Masahiro Kajino, Fumio Itoh, Naoki Tarui, Atsushi Hasuoka, Nobuhiro Inatomi, Keizo Hirase, Akio Imanishi, Terufumi Takagi, Haruyuki Nishida

المصدر: Bioorganicmedicinal chemistry letters. 25(10)

مصطلحات موضوعية: Stereochemistry, ATPase, Potassium, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, chemistry.chemical_element, Ring (chemistry), Biochemistry, Hydrocarbons, Aromatic, H(+)-K(+)-Exchanging ATPase, Inhibitory Concentration 50, Heterocyclic Compounds, Drug Discovery, Side chain, Moiety, Potency, Molecular Biology, Lone pair, biology, Molecular Structure, Chemistry, Organic Chemistry, In vitro, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbd9af2102df0d430832c5da6ce8e8e
https://pubmed.ncbi.nlm.nih.gov/25891103

المؤلفون: Kozo Matsushita, Masao Toyoda, Takahiro Tanaka, Yasuhiro Tsukimi, Kasei Miura, Nobuhiro Inatomi, Gaku Mizojiri, Akihiro Nakamura, Akio Imanishi, Akiko Tanaka, Shiho Matsumoto-Okano

المصدر: Journal of Pharmacological Sciences, Vol 120, Iss 1, Pp 15-25 (2012)

مصطلحات موضوعية: Agonist, Adult, Male, medicine.medical_specialty, medicine.drug_class, Colon, Guinea Pigs, Substance P, In Vitro Techniques, Cell Line, Irritable Bowel Syndrome, chemistry.chemical_compound, Internal medicine, medicine, Hypersensitivity, Animals, Humans, Benzamide, Defecation, Aged, Pharmacology, Aged, 80 and over, business.industry, lcsh:RM1-950, Antagonist, Muscle, Smooth, Receptors, Neurokinin-3, Receptors, Neurokinin-2, Middle Aged, Receptors, Neurokinin-1, Endocrinology, lcsh:Therapeutics. Pharmacology, chemistry, Alosetron, Benzamides, Quinolines, Molecular Medicine, Female, Serotonin, Neurokinin A, Rabbits, Neurokinin B, business, Ricinoleic Acids, medicine.drug, Muscle Contraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8319fe77d7247ea80d605f205fbd8c
https://pubmed.ncbi.nlm.nih.gov/22893394