المؤلفون: Yoshihiro Konno, Shunsuke Kamigaso, Hidetoh Toki, Shuichi Terasaka, Hirohiko Hikichi, Hiromi Endo, Jun‐Ichi Yamaguchi, Akiko Mizuno‐Yasuhira

المصدر: Pharmacology Research & Perspectives, Vol 12, Iss 2, Pp n/a-n/a (2024)

مصطلحات موضوعية: disposition, half‐life, metabolism, orexin, pharmacokinetic, TS‐142, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2052-1707

URL الوصول: https://doaj.org/article/f0fdc42495644a57a4587a112985bc33

المؤلفون: Takuya Saito, Yushiro Yamashita, Akemi Tomoda, Takashi Okada, Hideo Umeuchi, Saki Iwamori, Satoru Shinoda, Akiko Mizuno-Yasuhira, Hidetoshi Urano, Izumi Nishino, Kazuhiko Saito

المصدر: BMC Psychiatry, Vol 20, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: Drug repositioning, TS-141, ADHD, CYP2D6 polymorphism, Phenotype, Clinical trial, Psychiatry, RC435-571

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12888-020-02932-2; https://doaj.org/toc/1471-244X

URL الوصول: https://doaj.org/article/770419312d724d3f834510d3df448818

المؤلفون: Hiroki Takano, Akiko Mizuno-Yasuhira, Jun-ichi Yamaguchi, Hiromi Endo

المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 52(7)

مصطلحات موضوعية: Pharmacology, Health, Toxicology and Mutagenesis, General Medicine, Toxicology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97137735bc56fd58fc3aeff2fd09beb4
https://pubmed.ncbi.nlm.nih.gov/36371761

المؤلفون: Izumi Nishino, Hiromi Endo, Makoto Kamiya, Shoko Inatani, Akiko Mizuno-Yasuhira, Helene D. Sabia

المصدر: Biopharmaceutics & Drug Disposition

مصطلحات موضوعية: Male, Receptors, Vasopressin, Vasopressin, Cell Membrane Permeability, Pharmaceutical Science, Phases of clinical research, THY1773, Pharmacology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, 0302 clinical medicine, Cytochrome P-450 Enzyme System, receptor occupancy, Pharmacology (medical), effective dose prediction, medicine.diagnostic_test, Blood Proteins, Fasting, General Medicine, Middle Aged, V1B receptor, Receptor antagonist, Original Papers, Effective dose (pharmacology), Phenotype, Treatment Outcome, Drug development, Positron emission tomography, 030220 oncology & carcinogenesis, Microsomes, Liver, Female, TS‐121, Antidiuretic Hormone Receptor Antagonists, Protein Binding, Adult, Physiologically based pharmacokinetic modelling, medicine.drug_class, Models, Biological, Young Adult, 03 medical and health sciences, Dogs, Double-Blind Method, Pharmacokinetics, medicine, Animals, Humans, business.industry, Reproducibility of Results, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0d5283d2b427dee2f38052c32d7c7d
https://doi.org/10.1002/bdd.2273

المؤلفون: Hidetoh Toki, Jun-ichi Yamaguchi, Akiko Mizuno-Yasuhira, Hiromi Endo

المصدر: Journal of pharmaceutical and biomedical analysis. 224

مصطلحات موضوعية: Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Spectroscopy, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9989b80bd66a992d8d23d98db83ff99a
https://pubmed.ncbi.nlm.nih.gov/36473323

المؤلفون: Satoru Shinoda, Akiko Mizuno-Yasuhira, Yushiro Yamashita, Akemi Tomoda, Hidetoshi Urano, Kazuhiko Saito, Hideo Umeuchi, Izumi Nishino, Takashi Okada, Saki Iwamori, Takuya Saito

المصدر: BMC Psychiatry
BMC Psychiatry, Vol 20, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: Adult, medicine.medical_specialty, Dose, Adolescent, lcsh:RC435-571, Phases of clinical research, Subgroup analysis, Placebo, behavioral disciplines and activities, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Japan, Piperidines, lcsh:Psychiatry, Internal medicine, Medicine, Attention deficit hyperactivity disorder, Humans, ADHD, Child, Tipepidine, Psychiatric Status Rating Scales, Dose-Response Relationship, Drug, business.industry, Therapeutic effect, Drug repositioning, medicine.disease, 030227 psychiatry, Clinical trial, Psychiatry and Mental health, Treatment Outcome, Phenotype, Attention Deficit Disorder with Hyperactivity, CYP2D6 polymorphism, Delayed-Action Preparations, Central Nervous System Stimulants, business, TS-141, 030217 neurology & neurosurgery, medicine.drug, Tablets, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df5701680f42cd063d318ec5992b923
https://pubmed.ncbi.nlm.nih.gov/33167920

المؤلفون: Akiko Mizuno-Yasuhira, Hidetoh Toki, Takuya Ichikawa, Junichi Yamaguchi

المصدر: Journal of Pharmaceutical and Biomedical Analysis. 148:288-297

مصطلحات موضوعية: Male, Electrospray, Clinical Biochemistry, Pharmaceutical Science, Mass spectrometry, 01 natural sciences, Analytical Chemistry, Matrix (chemical analysis), Mice, Plasma, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Pharmacokinetics, Tandem Mass Spectrometry, Drug Discovery, medicine, Animals, Ketamine, Spectroscopy, Cerebrospinal Fluid, Chromatography, Chemistry, 010401 analytical chemistry, Brain, Reproducibility of Results, Stereoisomerism, Antidepressive Agents, 0104 chemical sciences, Mice, Inbred C57BL, Substance Abuse Detection, Calibration, Stereoselectivity, Enantiomer, 030217 neurology & neurosurgery, Chromatography, Liquid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4ac7e366bb1d3bf83b2b59d1d9f010
https://doi.org/10.1016/j.jpba.2017.09.033

المؤلفون: Tetsuhiro Nemoto, Yuko Fujita, Lijia Chang, Hidetoh Toki, Shingo Harada, Shigeyuki Chaki, Kenji Hashimoto, Min Ma, Youge Qu, Kai Zhang, Akiko Mizuno-Yasuhira, Junichi Yamaguchi

المصدر: Psychopharmacology. 235(11)

مصطلحات موضوعية: Male, medicine.medical_specialty, Metabolite, Social defeat, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Pharmacokinetics, Internal medicine, Kinetic isotope effect, medicine, Animals, Ketamine, Pharmacology, Depression, Antagonist, Brain, Deuterium, Antidepressive Agents, 030227 psychiatry, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, Treatment Outcome, chemistry, Chronic Disease, NMDA receptor, Antidepressant, 030217 neurology & neurosurgery, Stress, Psychological, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681032020c5d43d75ccba88966a02c6c
https://pubmed.ncbi.nlm.nih.gov/30215218

المؤلفون: Lijia Chang, Hidetoh Toki, Yuko Fujita, Shigeyuki Chaki, Youge Qu, Kenji Hashimoto, Akiko Mizuno-Yasuhira, Junichi Yamaguchi

المصدر: International Journal of Neuropsychopharmacology

مصطلحات موضوعية: Lipopolysaccharides, Male, Lipopolysaccharide, medicine.medical_treatment, (2R,6R)-hydroxynorketamine, Inflammation, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Pharmacokinetics, sex-specific difference, medicine, Animals, Pharmacology (medical), Ketamine, Saline, Sex Characteristics, business.industry, Brain, Immobility Response, Tonic, Stereoisomerism, 030227 psychiatry, Psychiatry and Mental health, chemistry, Antidepressant, Female, Brief Reports, medicine.symptom, business, 030217 neurology & neurosurgery, (R)-ketamine, Behavioural despair test, medicine.drug, Sex characteristics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900ef9f719335d72a4a30e507ec56550
https://pubmed.ncbi.nlm.nih.gov/29893929

المؤلفون: Junichi Yamaguchi, Kohnosuke Kinoshita, Shigeji Jingu, Akiko Mizuno-Yasuhira

المصدر: Biomedical Chromatography. 28:1423-1429

مصطلحات موضوعية: Pharmacology, Chromatography, Chemistry, Electrospray ionization, Clinical Biochemistry, Selected reaction monitoring, Analytical chemistry, Ion suppression in liquid chromatography–mass spectrometry, General Medicine, Mass spectrometry, Tandem mass spectrometry, Biochemistry, Analytical Chemistry, Liquid chromatography–mass spectrometry, Drug Discovery, Protein precipitation, Solid phase extraction, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f6cff3f4f3900ce7055cc347f117bb48
https://doi.org/10.1002/bmc.3185

المؤلفون: Yoshishige Samukawa, Kenji Hachiuma, Junichi Yamaguchi, Shigeji Jingu, Haruyuki Mori, Yasuhiro Nakai, Nobuko Horiuchi, Soichi Sakai, Akiko Mizuno-Yasuhira, Yukihiro Chino, Masatoshi Hasegawa, Atsunori Miyata

المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 47(4)

مصطلحات موضوعية: Glucuronosyltransferase, Health, Toxicology and Mutagenesis, Metabolite, Glucuronidation, Aldehyde dehydrogenase, Pharmacology, Toxicology, Hydroxylation, 030226 pharmacology & pharmacy, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cytochrome P-450 Enzyme System, Cytochrome P-450 CYP3A, Humans, Sorbitol, Sodium-Glucose Transporter 2 Inhibitors, Alcohol dehydrogenase, chemistry.chemical_classification, biology, General Medicine, Metabolism, Metabolic pathway, Kinetics, Enzyme, Glucose, chemistry, 030220 oncology & carcinogenesis, UDP-Glucuronosyltransferase 1A9, biology.protein, Microsomes, Liver, Oxidation-Reduction, Metabolic Networks and Pathways

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ad3fd979b62067fb35edb2bf64092f
https://pubmed.ncbi.nlm.nih.gov/27347703

المؤلفون: Junichi Yamaguchi, Emi Gunji, Shigeji Jingu, Kohnosuke Kinoshita, Teisuke Takahashi, Akiko Mizuno-Yasuhira, Yasuhiro Nakai, Soichi Sakai, Saeko Uchida, Yoshishige Samukawa

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 42(9)

مصطلحات موضوعية: Drug, Male, 1-Deoxynojirimycin, media_common.quotation_subject, Cmax, Pharmaceutical Science, Absorption (skin), CHO Cells, Pharmacology, Models, Biological, Cell Line, Rats, Sprague-Dawley, Cricetulus, Sodium-Glucose Transporter 1, Pharmacokinetics, In vivo, medicine, Animals, Humans, Sorbitol, Computer Simulation, Drug Interactions, Intestinal Mucosa, media_common, Concomitant Agent, Chemistry, Miglitol, Membrane Transport Proteins, Transporter, Rats, Intestinal Absorption, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac02aa1f09358341b3d71a66d185d11
https://pubmed.ncbi.nlm.nih.gov/25005603

المؤلفون: Akiko, Mizuno-Yasuhira, Kohnosuke, Kinoshita, Shigeji, Jingu, Jun-ichi, Yamaguchi

المصدر: Biomedical chromatography : BMC. 28(10)

مصطلحات موضوعية: Male, Rats, Sprague-Dawley, 1-Deoxynojirimycin, Drug Stability, Tandem Mass Spectrometry, Solid Phase Extraction, Linear Models, Temperature, Animals, Reproducibility of Results, Sensitivity and Specificity, Chromatography, Liquid, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6879a62570a3179633ad9445229ee84d
https://pubmed.ncbi.nlm.nih.gov/24706526

المؤلفون: Akiko Mizuno-Yasuhira, Shigeru Okuyama, Shigeji Jingu

المصدر: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

مصطلحات موضوعية: Blood Glucose, Male, Calibration curve, Electrospray ionization, Clinical Biochemistry, Analytical chemistry, Tandem mass spectrometry, Biochemistry, Sensitivity and Specificity, Analytical Chemistry, Rats, Sprague-Dawley, Drug Stability, Tandem Mass Spectrometry, Protein precipitation, Animals, Humans, Sample preparation, Solid phase extraction, Chromatography, Chemistry, Selected reaction monitoring, Solid Phase Extraction, Reproducibility of Results, Cell Biology, General Medicine, Rats, Glucose, Distilled water, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdee2be18b9f12f1d893d4d273e22891
https://pubmed.ncbi.nlm.nih.gov/22222628