المؤلفون: Kazuhiko Nakagawa, Hironobu Minami, Masayuki Kanezaki, Akihira Mukaiyama, Yoshiyuki Minamide, Hisao Uejima, Takayasu Kurata, Toshiji Nogami, Kenji Kawada, Hirofumi Mukai, Yasutsuna Sasaki, Masahiro Fukuoka

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jjco.oxfordjournals.org/content/39/2/116.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.1222; http://jjco.oxfordjournals.org/content/39/2/116.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.1222
http://jjco.oxfordjournals.org/content/39/2/116.full.pdf

المؤلفون: Fanghong Zhang, Akihira Mukaiyama, Yoshio Kiyohara, Naoya Yamazaki, Noboru Yamamoto, Tomohide Tamura, Shusuke Yoshikawa, Kenjiro Namikawa, Arata Tsutsumida, Hiroshi Nokihara, Yutaka Fujiwara

المصدر: Investigational New Drugs. 36:259-268

مصطلحات موضوعية: Pharmacology, Oncology, medicine.medical_specialty, Leukopenia, Nausea, business.industry, Melanoma, Hyperkeratosis, Dabrafenib, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Tolerability, 030220 oncology & carcinogenesis, Internal medicine, medicine, Clinical endpoint, Pharmacology (medical), 030212 general & internal medicine, medicine.symptom, Adverse effect, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9dfd06dce4da7395250df48818473c1a
https://doi.org/10.1007/s10637-017-0502-8

المؤلفون: Atsuko Takasu, Yasuhito Fujisaka, Kazuhiko Nakagawa, Daisuke Naruge, Yuichiro Nishimura, Junji Furuse, Shinichi Nishina, Takayasu Kurata, Akihira Mukaiyama, Hideki Matsushita, Fumio Nagashima, Wataru Okamoto, Toshio Shimizu, Akiyoshi Kasuga, Hiroshi Kitamura

المصدر: Investigational New Drugs. 33:1058-1067

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Maximum Tolerated Dose, Pyridones, Antineoplastic Agents, Pyrimidinones, Deoxycytidine, chemistry.chemical_compound, Asian People, Japan, Neoplasms, Internal medicine, medicine, Humans, Pharmacology (medical), Kinase activity, Adverse effect, Aged, Pharmacology, Trametinib, Dose-Response Relationship, Drug, business.industry, Cancer, Middle Aged, medicine.disease, Gemcitabine, Rash, Surgery, Pancreatic Neoplasms, Tolerability, chemistry, Area Under Curve, Drug Therapy, Combination, Female, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ac8fbcc962bf2a86cf5f5b0372caf0
https://doi.org/10.1007/s10637-015-0270-2

المؤلفون: Yoshio Kiyohara, Kenjiro Namikawa, Shunsuke Kondo, Arata Tsutsumida, Naoya Yamazaki, Akira Takahashi, Fanghong Zhang, Yutaka Fujiwara, Shusuke Yoshikawa, Akihira Mukaiyama

المصدر: The Journal of Dermatology

مصطلحات موضوعية: Oncology, Male, Skin Neoplasms, Peripheral edema, Kaplan-Meier Estimate, 0302 clinical medicine, Japan, Antineoplastic Combined Chemotherapy Protocols, Oximes, 030212 general & internal medicine, Melanoma, Trametinib, trametinib, Imidazoles, General Medicine, Middle Aged, Treatment Outcome, Tolerability, 030220 oncology & carcinogenesis, Female, Original Article, medicine.symptom, medicine.drug, Adult, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Combination therapy, Pyridones, malignant melanoma, Dermatology, Pyrimidinones, Disease-Free Survival, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Humans, dabrafenib, Adverse effect, Aged, business.industry, Dabrafenib, Original Articles, medicine.disease, Cutaneous melanoma, Mutation, Japanese, solid tumor, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db32675b07929ac4d275a5d2b520bb1e
https://pubmed.ncbi.nlm.nih.gov/29399853

المؤلفون: Yutaka, Fujiwara, Naoya, Yamazaki, Yoshio, Kiyohara, Shusuke, Yoshikawa, Noboru, Yamamoto, Arata, Tsutsumida, Hiroshi, Nokihara, Kenjiro, Namikawa, Akihira, Mukaiyama, Fanghong, Zhang, Tomohide, Tamura

المصدر: Investigational new drugs. 36(2)

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, Treatment Outcome, Asian People, Dose-Response Relationship, Drug, Neoplasms, Mutation, Oximes, Imidazoles, Humans, Female, Middle Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::07664d291c0819a8044026e9d3904710
https://pubmed.ncbi.nlm.nih.gov/28879519

المؤلفون: Noriyuki Masuda, Shinzoh Kudoh, Kaoru Matsui, Kazuhiko Nakagawa, Pascal Yoshida, Toshiyuki Ijima, Minoru Takada, Masahiro Fukuoka, Shunichi Negoro, Koji Takeda, Akihira Mukaiyama, Hiroaki Arase

المصدر: Clinical Lung Cancer. 11:271-279

مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Maximum Tolerated Dose, Urology, Salvage therapy, Antineoplastic Agents, Adenocarcinoma, Neutropenia, Bolus (medicine), Pharmacokinetics, Carcinoma, Non-Small-Cell Lung, medicine, Carcinoma, Humans, Tissue Distribution, Lung cancer, Survival rate, Aged, Salvage Therapy, business.industry, Middle Aged, medicine.disease, Surgery, Survival Rate, Treatment Outcome, Oncology, Drug Resistance, Neoplasm, Carcinoma, Squamous Cell, Female, Topotecan, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c2838cd62739ed91a9144a4cbe5cb1
https://doi.org/10.3816/clc.2010.n.035

المؤلفون: Yasushi Omuro, Akihito Tsuji, Jifeng Feng, Toshihiko Doi, Guo-ping Sun, Atsushi Ohtsu, Ik-Joo Chung, Yung-Jue Bang, Kun-Huei Yeh, Rui-Hua Xu, Shukui Qin, Hyun Cheol Chung, Taroh Satoh, Jianming Xu, Akihira Mukaiyama, Jin Li, Mikiro Kobayashi, Hiroto Miwa, Jinwan Wang

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 32(19)

مصطلحات موضوعية: Oncology, Adult, Male, Cancer Research, medicine.medical_specialty, Paclitaxel, Receptor, ErbB-2, medicine.medical_treatment, Population, Pilot Projects, Kaplan-Meier Estimate, Pharmacology, Lapatinib, Drug Administration Schedule, law.invention, chemistry.chemical_compound, Randomized controlled trial, Asian People, law, Trastuzumab, Stomach Neoplasms, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Clinical endpoint, Biomarkers, Tumor, Odds Ratio, Humans, skin and connective tissue diseases, education, In Situ Hybridization, Fluorescence, Aged, education.field_of_study, business.industry, Middle Aged, Antineoplastic Agents, Phytogenic, Treatment Outcome, chemistry, Area Under Curve, Quinazolines, Immunohistochemistry, Gastrectomy, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e93665f37d0d26dd7b58fcc91fcd21f
https://pubmed.ncbi.nlm.nih.gov/24868024

المؤلفون: Yutaka Fujiwara, Naoya Yamazaki, Yoshio Kiyohara, Shusuke Yoshikawa, Noboru Yamamoto, Arata Tsutsumida, Hiroshi Nokihara, Kenjiro Namikawa, Akihira Mukaiyama, Fanghong Zhang, Tomohide Tamura

المصدر: Investigational New Drugs; Apr2018, Vol. 36 Issue 2, p259-268, 10p

مصطلحات موضوعية: ANTINEOPLASTIC agents, BALDNESS, CLINICAL trials, DRUG tolerance, LEUCOPENIA, MELANOMA, GENETIC mutation, NAUSEA, ONCOGENES, PATIENT safety, PROTEIN kinases, THYROID gland tumors, TUMORS, TREATMENT effectiveness, JOINT pain

مصطلحات جغرافية: JAPAN

المؤلفون: Hisao Uejima, Hirofumi Mukai, Kenji Kawada, Kazuhiko Nakagawa, Toshiji Nogami, Yasutsuna Sasaki, Yoshiyuki Minamide, Masayuki Kanezaki, Masahiro Fukuoka, Hironobu Minami, Takayasu Kurata, Akihira Mukaiyama

المصدر: Japanese journal of clinical oncology. 39(2)

مصطلحات موضوعية: Adult, Cancer Research, medicine.medical_specialty, medicine.drug_class, Receptor, ErbB-2, Administration, Oral, Antineoplastic Agents, Pharmacology, Lapatinib, Gastroenterology, Tyrosine-kinase inhibitor, Pharmacokinetics, Asian People, Japan, ErbB, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, skin and connective tissue diseases, Adverse effect, Aged, business.industry, General Medicine, Middle Aged, Protein-Tyrosine Kinases, Rash, Clinical trial, ErbB Receptors, Oncology, Toxicity, Quinazolines, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9f9e2ca0856b1ede991b2ef0f11335
https://pubmed.ncbi.nlm.nih.gov/19052038

المؤلفون: Naoya Yamazaki, Y. Yoshino, S. Yoshikawa, Akihira Mukaiyama, Y. Nishimura, A. Suzuki, Arata Tsutsumida, Yutaka Fujiwara, A. Takahashi, Kenjiro Namikawa, Shunsuke Kondo, Yoshio Kiyohara

المصدر: Annals of Oncology. 26:ix103

مصطلحات موضوعية: Trametinib, Oncology, Pharmacokinetics, business.industry, Cutaneous melanoma, BRAF V600 Mutation, Cancer research, Medicine, Dabrafenib, Safety tolerability, Hematology, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::41c77f1fa57aeb5751caca4a1ace0e84
https://doi.org/10.1093/annonc/mdv528.03

المؤلفون: Yasuhito Fujisaka, Wataru Okamoto, Junji Furuse, Daisuke Naruge, Atsuko Takasu, Kazuhiko Nakagawa, Toshio Shimizu, Akiyoshi Kasuga, Hiroshi Kitamura, Koichi Katsura, Akihira Mukaiyama, Isamu Okamoto, Hideki Matsushita, Takayasu Kurata, Fumio Nagashima

المصدر: Journal of Clinical Oncology. 31:e20004-e20004

مصطلحات موضوعية: Trametinib, Cancer Research, Oncology, business.industry, Allosteric regulation, Cancer research, medicine, Pharmacology, business, Gemcitabine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9cfa291b9b92573bf4882fd9341f3a7e
https://doi.org/10.1200/jco.2013.31.15_suppl.e20004

المؤلفون: Taroh Satoh, Rui-Hua Xu, Hyun Cheol Chung, Guo-Ping Sun, Toshihiko Doi, Jian-Ming Xu, Akihito Tsuji, Yasushi Omuro, Jin Li, Jin-Wan Wang, Hiroto Miwa, Shu-Kui Qin, Ik-Joo Chung, Kun-Huei Yeh, Ji-Feng Feng, Akihira Mukaiyama, Mikiro Kobayashi, Atsushi Ohtsu, Yung-Jue Bang

المصدر: Journal of Clinical Oncology; 7/1/2014, Vol. 32 Issue 19, p2039-2049, 17p