المؤلفون: Blomqvist, Kim J., Skogster, Moritz O. B., Kurkela, Mika J., Rosenholm, Marko P., Ahlström, Fredrik H. G., Airavaara, Mikko T., Backman, Janne T., Rauhala, Pekka V., Kalso, Eija A., Lilius, Tuomas O.

المساهمون: INDIVIDRUG - Individualized Drug Therapy, Department of Pharmacology, Faculty of Medicine, Medicum, Department of Clinical Pharmacology, Helsinki University Hospital Area, Helsinki Institute of Sustainability Science (HELSUS), Drug Research Program, Division of Pharmacology and Pharmacotherapy, Divisions of Faculty of Pharmacy, Neuroscience Center, HUSLAB, Janne Backman / Principal Investigator, Clinicum, Pekka Rauhala / Principal Investigator, HUS Perioperative, Intensive Care and Pain Medicine, Eija Kalso / Principal Investigator, Department of Diagnostics and Therapeutics, Anestesiologian yksikkö, SLEEPWELL Research Program, HUS Emergency Medicine and Services

مصطلحات موضوعية: Neurosciences, Biomedicine, Glymphatic system, Drug delivery, Spinal cord, Opioids, Analgesia, Osmosis, BLOOD-BRAIN-BARRIER, CEREBROSPINAL-FLUID, RAT-BRAIN, PAIN, PENETRATION, ANESTHESIA, CLEARANCE, INJECTION, DRUGS

وصف الملف: application/pdf

Relation: Blomqvist , K J , Skogster , M O B , Kurkela , M J , Rosenholm , M P , Ahlström , F H G , Airavaara , M T , Backman , J T , Rauhala , P V , Kalso , E A & Lilius , T O 2022 , ' Systemic hypertonic saline enhances glymphatic spinal cord delivery of lumbar intrathecal morphine ' , Journal of Controlled Release , vol. 344 , pp. 214–224 . https://doi.org/10.1016/j.jconrel.2022.03.022; ORCID: /0000-0002-9577-2788/work/114604007; ORCID: /0000-0003-2036-3522/work/114604549; ORCID: /0000-0002-2026-1609/work/114604972; ORCID: /0000-0002-5437-8282/work/114607713; ORCID: /0000-0002-0926-6273/work/114608131; http://hdl.handle.net/10138/345181; 6cb3624c-7ae4-4678-8d16-750388507b19; 000802754800001

الاتاحة: http://hdl.handle.net/10138/345181

المؤلفون: Blomqvist, Kim J., Skogster, Moritz O. B., Kurkela, Mika J., Rosenholm, Marko P., Ahlström, Fredrik H. G., Airavaara, Mikko T., Backman, Janne T., Rauhala, Pekka V., Kalso, Eija A., Lilius, Tuomas O.

المساهمون: Individualized Drug Therapy, Farmakologian osasto, Lääketieteellinen tiedekunta, Medicum, Kliinisen farmakologian osasto, HYKS-sairaanhoitoalue, Kestävyystieteen instituutti (HELSUS), Drug Research Program, Farmakologian ja lääkehoidon osasto, Farmasian tiedekunnan osastot, Neurotieteen tutkimuskeskus, HUSLAB, Janne Backman / Vastuullinen tutkija, Clinicum, Pekka Rauhala / Vastuullinen tutkija, HUS Leikkaussalit, teho- ja kivunhoito, Eija Kalso / Vastuullinen tutkija, Diagnostis-terapeuttinen osasto, Anestesiologian yksikkö, Sleep and stress in health and in transition from acute to chronic diseases (SLEEPWELL), HUS Akuutti

مصطلحات موضوعية: Neurotieteet, Biolääketieteet, Glymphatic system, Drug delivery, Spinal cord, Opioids, Analgesia, Osmosis, BLOOD-BRAIN-BARRIER, CEREBROSPINAL-FLUID, RAT-BRAIN, PAIN, PENETRATION, ANESTHESIA, CLEARANCE, INJECTION, DRUGS

وصف الملف: application/pdf

Relation: Blomqvist , K J , Skogster , M O B , Kurkela , M J , Rosenholm , M P , Ahlström , F H G , Airavaara , M T , Backman , J T , Rauhala , P V , Kalso , E A & Lilius , T O 2022 , ' Glymfaattinen järjestelmä saattaa intratekaalisen lääkkeen selkäytimeen ' , Duodecim , Vuosikerta. 138 , Nro 10 , Sivut 949 . < https://www.duodecimlehti.fi/lehti/2022/10/duo16806 >; ORCID: /0000-0002-2026-1609/work/152926078; ORCID: /0000-0003-2036-3522/work/152927082; ORCID: /0000-0002-0926-6273/work/152930866; ORCID: /0000-0002-9577-2788/work/152931850; ORCID: /0000-0002-5437-8282/work/152932680; http://hdl.handle.net/10138/570954; 31da3107-beb1-492b-ab06-d42efb1bcf32

الاتاحة: http://hdl.handle.net/10138/570954