المؤلفون: Yan Lu (32611), Hongyue Liu (3106632), Dehua Yang (214814), Li Zhong (51791), Ye Xin (4814190), Suwen Zhao (1373610), Ming-Wei Wang (51951), Qingtong Zhou (1467937), Wenqing Shui (846991)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, data acquisition speed, NAM, affinity MS-based fragment screening, in-solution NMR analyses, SAR, Molecular dynamics simulations, HMA, sodium ion pocket, Sodium Ion Pocket Allosteric ligands, Affinity Mass Spectrometry-Based Fr., allosteric sodium binding site, Negative allosteric modulators, affinity mass spectrometry, surface plasmon resonance, G protein-coupled receptor, AR, GPCR target

Relation: https://figshare.com/articles/journal_contribution/Affinity_Mass_Spectrometry-Based_Fragment_Screening_Identified_a_New_Negative_Allosteric_Modulator_of_the_Adenosine_A_sub_2A_sub_Receptor_Targeting_the_Sodium_Ion_Pocket/14700235

الاتاحة: https://doi.org/10.1021/acschembio.0c00899.s001

المؤلفون: Yan Lu (32611), Hongyue Liu (3106632), Dehua Yang (214814), Li Zhong (51791), Ye Xin (4814190), Suwen Zhao (1373610), Ming-Wei Wang (51951), Qingtong Zhou (1467937), Wenqing Shui (846991)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, data acquisition speed, NAM, affinity MS-based fragment screening, in-solution NMR analyses, SAR, Molecular dynamics simulations, HMA, sodium ion pocket, Sodium Ion Pocket Allosteric ligands, Affinity Mass Spectrometry-Based Fr., allosteric sodium binding site, Negative allosteric modulators, affinity mass spectrometry, surface plasmon resonance, G protein-coupled receptor, AR, GPCR target

Relation: https://figshare.com/articles/dataset/Affinity_Mass_Spectrometry-Based_Fragment_Screening_Identified_a_New_Negative_Allosteric_Modulator_of_the_Adenosine_A_sub_2A_sub_Receptor_Targeting_the_Sodium_Ion_Pocket/14700238

الاتاحة: https://doi.org/10.1021/acschembio.0c00899.s002