المؤلفون: Charina M. Ramirez, Adam M. Lopez, Stephen D. Turley

المصدر: EBioMedicine, Vol 2, Iss 7, Pp 638-639 (2015)

مصطلحات موضوعية: Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396415300372; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/16c4410e00d748489a3d2c80f87e1489

المؤلفون: Stephen D. Turley, Charina M. Ramirez, Joyce J. Repa, Amal Aqul, Dennis K. Burns, Adam M. Lopez

المصدر: Lipids

مصطلحات موضوعية: medicine.medical_specialty, Central nervous system, Inflammation, Biochemistry, Article, Mice, chemistry.chemical_compound, Internal medicine, medicine, Animals, Homeostasis, Gene, Cholesterol Ester Storage Disease, Chemistry, Catabolism, Cholesterol, Organic Chemistry, Wolman Disease, Brain Mass, Brain, Cell Biology, Sterol Esterase, Phenotype, Endocrinology, medicine.anatomical_structure, Liver, medicine.symptom, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce68ca4e6c61d684674b28ab9c3d2ca
https://doi.org/10.1002/lipd.12325

المؤلفون: Amika Singla, Ezra Burstein, Jie Song, Lois S. Weisman, Sai Srinivas Panapakkam Giridharan, Alina Fedoseienko, Kayci Huff-Hardy, Brittany L. Overlee, Daniel D. Billadeau, Adam M. Lopez, Da Jia

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Cell biology, Endosome, Protein subunit, Science, Phosphatase, Vesicular Transport Proteins, General Physics and Astronomy, Endosomes, Protein tyrosine phosphatase, Biochemistry, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Phosphatidylinositol Phosphates, Cell Line, Tumor, Animals, Humans, Phosphorylation, RNA, Small Interfering, lcsh:Science, Adaptor Proteins, Signal Transducing, Actin nucleation, Multidisciplinary, Chemistry, Microfilament Proteins, Membrane Proteins, Proteins, Signal transducing adaptor protein, General Chemistry, Protein Tyrosine Phosphatases, Non-Receptor, Actins, HEK293 Cells, 030104 developmental biology, Membrane protein, lcsh:Q, RNA Interference, Lysosomes, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9bda8a960b7d5543a91e1aad846b519
https://doaj.org/article/05e31276e2a744fdb7699f4e17f5be4d

المؤلفون: Adam M. Lopez, Ryan Jones, Anna M. Taylor, Joyce J. Repa, Stephen D. Turley, Charina M. Ramirez

المصدر: Digestive Diseases and Sciences. 65:158-167

مصطلحات موضوعية: Male, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Mice, 129 Strain, Physiology, Ontogeny, Spleen, Subcutaneous injection, Ezetimibe, Niemann-Pick C1 Protein, hemic and lymphatic diseases, Internal medicine, Intestine, Small, medicine, Animals, Intestinal Mucosa, Mice, Knockout, chemistry.chemical_classification, Mice, Inbred BALB C, Intracellular Signaling Peptides and Proteins, Gastroenterology, nutritional and metabolic diseases, Niemann-Pick Disease, Type C, Hepatology, Small intestine, 2-Hydroxypropyl-beta-cyclodextrin, nervous system diseases, Mice, Inbred C57BL, Disease Models, Animal, Cholesterol, Enzyme, medicine.anatomical_structure, Endocrinology, Intestinal Absorption, chemistry, Female, lipids (amino acids, peptides, and proteins), NPC1, Sterol O-Acyltransferase, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c4a314d38b0b606281913a2bf41bd4
https://doi.org/10.1007/s10620-019-05736-x

المؤلفون: Jie Song, Adam M. Lopez, Kohei Suzuki, Bart van de Sluis, Qing Chen, Alina Fedoseienko, Melinde Wijers, Daniel D. Billadeau, Ezra Burstein, Amika Singla

المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE)

المصدر: Disease Models & Mechanisms, Vol 14, Iss 1 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease models & mechanisms, 14. COMPANY OF BIOLOGISTS LTD

مصطلحات موضوعية: Protein family, atp7b, Endosome, atp7a, ATP7A, Neuroscience (miscellaneous), lcsh:Medicine, Medicine (miscellaneous), chemistry.chemical_element, Endosomes, General Biochemistry, Genetics and Molecular Biology, commd proteins, Mice, Immunology and Microbiology (miscellaneous), Cell Line, Tumor, lcsh:Pathology, Animals, Homeostasis, Humans, Gene, Adaptor Proteins, Signal Transducing, Mice, Knockout, Chemistry, lcsh:R, Ceruloplasmin, copper homeostasis, Transporter, copper transporters, Copper, Phenotype, Cell biology, Enterocytes, Gene Expression Regulation, endosomal trafficking, Copper-Transporting ATPases, Mutation, Hepatocytes, Function (biology), Research Article, lcsh:RB1-214

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc5ed9038d16f71c619ca6f6fe6f658
https://doi.org/10.1242/dmm.045963

المؤلفون: Adam M. Lopez, Charina M. Ramirez, Anna M. Taylor, Joyce J. Repa, Stephen D. Turley

المصدر: Steroids

مصطلحات موضوعية: Endosome, Clinical Biochemistry, Sterol O-acyltransferase, 030209 endocrinology & metabolism, Spleen, Pharmacology, Biochemistry, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Endocrinology, Niemann-Pick C1 Protein, hemic and lymphatic diseases, Lysosomal storage disease, medicine, Animals, Molecular Biology, SOAT1, Mice, Inbred BALB C, Chemistry, Endoplasmic reticulum, Organic Chemistry, nutritional and metabolic diseases, medicine.disease, Sterol, 2-Hydroxypropyl-beta-cyclodextrin, medicine.anatomical_structure, Cholesterol, Liver, 030220 oncology & carcinogenesis, lipids (amino acids, peptides, and proteins), NPC1, Sterol O-Acyltransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e944c7302c75dab836f654ebc55958f0
https://europepmc.org/articles/PMC7680374/

المؤلفون: Shuai Tan, Jacobo L. Santolaya, Qi Liu, Colin Bergstrom, Adam M. Lopez, Qing Chen, Goncalo Dias do Vale, Jeff McDonald, Luis Sifuentes-Dominguez, Ezra Burstein

المصدر: Gastroenterology. 162:S-95

مصطلحات موضوعية: Hepatology, Gastroenterology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a570c75e0d2f57d38c04e17cc085171e
https://doi.org/10.1016/s0016-5085(22)60238-5

المؤلفون: Jen Chieh Chuang, Stephen D. Turley, Anja Kerksiek, Dieter Lütjohann, Adam M. Lopez

المصدر: Lipids. 53:363-373

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Catabolism, Cholesterol, Lanosterol, Campesterol, Organic Chemistry, Lathosterol, Rett syndrome, Cell Biology, medicine.disease, Biochemistry, MECP2, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Endocrinology, chemistry, Desmosterol, Internal medicine, medicine, lipids (amino acids, peptides, and proteins), 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::01e8c6653d41e4730a852b3a0f69e79d
https://doi.org/10.1002/lipd.12041

المؤلفون: Qing Chen, Tiffany A. Reese, Amika Singla, Luis Sifuentes-Dominguez, Shelby D. Melton, Kayci Huff-Hardy, Emre E. Turer, Naoteru Miyata, Ernesto M. Llano, Wenhan Zhu, Haiying Li, Sebastian E. Winter, Curtis A. Thorne, Petro Starokadomskyy, Lindsey L. Morris, Adam M. Lopez, Daniel D. Billadeau, Ezra Burstein, Maria G. Winter

المصدر: Cell reports
Cell reports, vol 24, iss 9

مصطلحات موضوعية: 0301 basic medicine, intestinal microbiota, Myeloid, goblet cells, Colorectal cancer, Carcinogenesis, Cell, Medical Physiology, Tuft cells, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Oral and gastrointestinal, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Immune system, medicine, Compartment (development), 2.1 Biological and endogenous factors, Animals, Humans, Myeloid Cells, Aetiology, PGE-2, Cancer, Lamina propria, Inflammatory and immune system, Microbiota, Epithelial Cells, COX-2, medicine.disease, Mucus, 3. Good health, Cell biology, Colo-Rectal Cancer, Intestines, 030104 developmental biology, medicine.anatomical_structure, colon cancer, 030220 oncology & carcinogenesis, CCC complex, Commd1, Biochemistry and Cell Biology, Digestive Diseases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20c0c9cbcdf86a64d79c97640e58b8a
http://europepmc.org/articles/PMC6177233

المؤلفون: Adam M. Lopez, Stephen D. Turley, Jen Chieh Chuang

المصدر: Biochemical Pharmacology. 135:116-125

مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Enterocyte, medicine.drug_class, 030204 cardiovascular system & hematology, Biology, Biochemistry, Article, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ezetimibe, Internal medicine, Intestine, Small, medicine, Animals, Cholesterol absorption inhibitor, Mice, Knockout, Pharmacology, Cholesterol, Anticholesteremic Agents, Reverse cholesterol transport, Sterol Esterase, Small intestine, Sterol, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Liver, chemistry, Intestinal cholesterol absorption, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e4b48a4c638715659acc270f3bd858
https://doi.org/10.1016/j.bcp.2017.03.010

المؤلفون: Andrew R. Zinn, Luis Sifuentes-Dominguez, Aleksandra Gil-Krzewska, Katelynn M. Wilton, Petro Starokadomskyy, Ezra Burstein, Luis Rohena, Mary E. Peterson, Adam M. Lopez, Ann Ray, Brittany L. Overlee, Daniel D. Billadeau, Nick V. Grishin, Eyal Grunebaum, Konrad Krzewski, Qing Chen, Lisa N. Kinch

المصدر: JCI Insight

مصطلحات موضوعية: Cytotoxicity, Immunologic, 0301 basic medicine, DNA Repair, DNA polymerase, Cell, NK cells, Monogenic diseases, 03 medical and health sciences, 0302 clinical medicine, Minichromosome maintenance, Interferon, medicine, Humans, Gene, Inflammation, Innate immunity, Recombination, Genetic, Infectious disease, Okazaki fragments, biology, DNA replication, Skin Diseases, Genetic, Genetic Diseases, X-Linked, General Medicine, Molecular biology, Minichromosome Maintenance Complex Component 4, 3. Good health, Killer Cells, Natural, 030104 developmental biology, medicine.anatomical_structure, Lytic cycle, 030220 oncology & carcinogenesis, biology.protein, K562 Cells, Amyloidosis, Familial, Pigmentation Disorders, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23463523d69f19909851f2fcd7bc89e9
https://doi.org/10.1172/jci.insight.125688

المؤلفون: Jen Chieh Chuang, Adam M. Lopez, Kenneth S. Posey, Stephen D. Turley

المصدر: Brain Research. 1654:77-84

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Neuroscience(all), Clinical Neurology, Biology, Blood–brain barrier, MECP2, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Rett syndrome, Desmosterol, Internal medicine, CYP27A1, mental disorders, medicine, Molecular Biology, Fatty acid synthesis, Cholesterol, General Neuroscience, Lipid metabolism, nervous system diseases, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, chemistry, Ontogeny, Neurology (clinical), Brain weight, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f079774ef70641ae482bc1afbce20a

المؤلفون: Luis Sifuentes-Dominguez, Bujun Ge, Shuai Tan, Igor Dozmorov, Ezra Burstein, Petro Starokadomskyy, Purva Gopal, Qing Chen, Jie Song, Naoteru Miyata, Kohei Suzuki, Adam M. Lopez

المصدر: Life Science Alliance

مصطلحات موضوعية: Adenoma, Male, 0301 basic medicine, Paneth Cells, Carcinogenesis, Health, Toxicology and Mutagenesis, education, Mice, Transgenic, Context (language use), Plant Science, Biology, medicine.disease_cause, digestive system, Biochemistry, Genetics and Molecular Biology (miscellaneous), Wnt3 Protein, Mice, 03 medical and health sciences, 0302 clinical medicine, Intestine, Small, Genetic model, medicine, Animals, Small Intestinal Adenoma, Intestinal Mucosa, Research Articles, Ecology, Wnt signaling pathway, medicine.disease, Small intestine, Mice, Inbred C57BL, Organoids, Disease Models, Animal, Cell Transformation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Paneth cell, Cancer research, Intercellular Signaling Peptides and Proteins, Female, Colorectal Neoplasms, Research Article, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ee4a9540399768cc961b0c5b681597
https://doi.org/10.26508/lsa.202000934

المؤلفون: Petro Starokadomskyy, Adam M. Lopez, Qing Chen, Ezra Burstein, Shuai Tan, Kohei Suzuki, Luis Sifuentes-Dominguez

المصدر: Gastroenterology. 158:S-533

مصطلحات موضوعية: medicine.anatomical_structure, Hepatology, Paneth cell, Gastroenterology, Cancer research, medicine, Biology, Intestinal tumorigenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe739e98c0122a6c0f02bbfbf3f1a52e
https://doi.org/10.1016/s0016-5085(20)32027-8

المؤلفون: Stephen D. Turley, Ryan D. Jones, Adam M. Lopez, Joyce J. Repa

المصدر: American journal of physiology. Gastrointestinal and liver physiology. 315(4)

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Physiology, Endosome, Sterol O-acyltransferase, 03 medical and health sciences, Entrapment, Mice, 0302 clinical medicine, Niemann-Pick C1 Protein, Physiology (medical), Internal medicine, hemic and lymphatic diseases, medicine, Lysosomal storage disease, Animals, Unesterified cholesterol, Aspartate Aminotransferases, Mice, Inbred BALB C, Hepatology, Chemistry, Neurodegeneration, Gastroenterology, nutritional and metabolic diseases, Alanine Transaminase, medicine.disease, 030104 developmental biology, Endocrinology, Cholesterol, Liver, lipids (amino acids, peptides, and proteins), Female, Liver function, NPC1, 030217 neurology & neurosurgery, Sterol O-Acyltransferase, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56dccf0f0f8a4f569464ba1c5a41bd76
https://pubmed.ncbi.nlm.nih.gov/29878847

المؤلفون: Lawrence L. Rudel, Kenneth S. Posey, Taichi Ohshiro, Hiroshi Tomoda, Adam M. Lopez, Stephen D. Turley, Jen Chieh Chuang

المصدر: Journal of Pharmacology and Experimental Therapeutics. 355:159-167

مصطلحات موضوعية: Male, medicine.medical_specialty, Pyridines, Sterol O-acyltransferase, Inflammation, Biology, Hepatitis, Mice, chemistry.chemical_compound, Internal medicine, Intestine, Small, Sterol esterase, medicine, Animals, Transaminases, Mice, Knockout, Pharmacology, Cholesterol, Organ Size, Enzyme replacement therapy, Sterol Esterase, Sterol, Endocrinology, Liver, chemistry, Cholesteryl ester, Molecular Medicine, Female, Cholesterol Esters, Liver function, medicine.symptom, Sesquiterpenes, Gastrointestinal, Hepatic, Pulmonary, and Renal, Sterol O-Acyltransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657da254a2df112337acbda78ca9ccde
https://doi.org/10.1124/jpet.115.227207

المؤلفون: Jen Chieh Chuang, Stephen D. Turley, Ernest Y. Tong, Adam M. Lopez, Joyce J. Repa, Ryan D. Jones, Kenneth S. Posey

المصدر: Steroids. 93:87-95

مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.drug_class, Clinical Biochemistry, Muricholic acid, Gene Expression, Biology, Chenodeoxycholic Acid, Cholesterol 7 alpha-hydroxylase, Biochemistry, Article, Bile Acids and Salts, chemistry.chemical_compound, Endocrinology, Internal medicine, Chenodeoxycholic acid, Intestine, Small, medicine, Animals, Cholesterol 7-alpha-Hydroxylase, Molecular Biology, Mice, Knockout, Pharmacology, Bile acid, Cholesterol, FGF15, Organic Chemistry, Cholic acid, Lipid Metabolism, Liver, chemistry, Dietary Supplements, Female, CYP8B1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fcbb9ba4a185dd83502b9a757f4baf
https://doi.org/10.1016/j.steroids.2014.11.002

المؤلفون: Jen Chieh Chuang, Stephen D. Turley, Adam M. Lopez

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Clinical Biochemistry, Inflammation, Biochemistry, Article, Transaminase, 03 medical and health sciences, chemistry.chemical_compound, Mice, Endocrinology, Internal medicine, Intestine, Small, medicine, Animals, Molecular Biology, Gene, Pharmacology, chemistry.chemical_classification, Cholesterol, Organic Chemistry, Enzyme replacement therapy, Sterol Esterase, Sterol, Small intestine, Mice, Mutant Strains, Mice, Inbred C57BL, 030104 developmental biology, Enzyme, medicine.anatomical_structure, chemistry, Liver, medicine.symptom, Sterol O-Acyltransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4599288a898dd2b0771dcd1c8137d19a
https://europepmc.org/articles/PMC5760480/

المؤلفون: Dieter, Lütjohann, Adam M, Lopez, Jen-Chieh, Chuang, Anja, Kerksiek, Stephen D, Turley

المصدر: Lipids. 53(4)

مصطلحات موضوعية: Mice, Inbred C57BL, Disease Models, Animal, Mice, Behavior, Animal, Methyl-CpG-Binding Protein 2, Rett Syndrome, Animals, Brain, Lovastatin, Hydroxycholesterols

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ee83325651a3172322f1c54d90f20c03
https://pubmed.ncbi.nlm.nih.gov/29770459

المؤلفون: Stephen D. Turley, Adam M. Lopez, Kenneth S. Posey

المصدر: Biochemical and Biophysical Research Communications. 454:162-166

مصطلحات موضوعية: Male, medicine.medical_specialty, Sterol O-acyltransferase, Biophysics, Biochemistry, Article, Transaminase, Mice, chemistry.chemical_compound, Internal medicine, Intestine, Small, Sterol esterase, medicine, Animals, Humans, Aspartate Aminotransferases, Molecular Biology, Mice, Knockout, Cholesterol Ester Storage Disease, biology, Cholesterol, Alanine Transaminase, Cell Biology, Cholesterol ester storage disease, Sterol Esterase, Small intestine, Sterol, Disease Models, Animal, Endocrinology, medicine.anatomical_structure, Liver, chemistry, Alanine transaminase, Disease Progression, biology.protein, Female, Cholesterol Esters, Sterol O-Acyltransferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6ceeef162af240fcbe7357d5a01a75
https://doi.org/10.1016/j.bbrc.2014.10.063