المؤلفون: Nancy J. Newman, Patrick Yu-Wai-Man, Valerio Carelli, Valerie Biousse, Mark L. Moster, Catherine Vignal-Clermont, Robert C. Sergott, Thomas Klopstock, Alfredo A. Sadun, Jean-François Girmens, Chiara La Morgia, Adam A. DeBusk, Neringa Jurkute, Claudia Priglinger, Rustum Karanjia, Constant Josse, Julie Salzmann, François Montestruc, Michel Roux, Magali Taiel, José-Alain Sahel

المصدر: Frontiers in Neurology, Vol 12 (2021)

مصطلحات موضوعية: Leber hereditary optic neuropathy, ND4, gene therapy, natural history, visual acuity, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2021.662838/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/aa106b3a79bb4d9f8dfa916c23b50638

المؤلفون: Valerio, Carelli, Nancy J, Newman, Patrick, Yu-Wai-Man, Valerie, Biousse, Mark L, Moster, Prem S, Subramanian, Catherine, Vignal-Clermont, An-Guor, Wang, Sean P, Donahue, Bart P, Leroy, Robert C, Sergott, Thomas, Klopstock, Alfredo A, Sadun, Gema, Rebolleda Fernández, Bart K, Chwalisz, Rudrani, Banik, Jean François, Girmens, Chiara, La Morgia, Adam A, DeBusk, Neringa, Jurkute, Claudia, Priglinger, Rustum, Karanjia, Constant, Josse, Julie, Salzmann, François, Montestruc, Michel, Roux, Magali, Taiel, José-Alain, Sahel, Rod, Forooza

المساهمون: Carelli, Valerio, Newman, Nancy J, Yu-Wai-Man, Patrick, Biousse, Valerie, Moster, Mark L, Subramanian, Prem S, Vignal-Clermont, Catherine, Wang, An-Guor, Donahue, Sean P, Leroy, Bart P, Sergott, Robert C, Klopstock, Thoma, Sadun, Alfredo A, Rebolleda Fernández, Gema, Chwalisz, Bart K, Banik, Rudrani, Girmens, Jean Françoi, La Morgia, Chiara, DeBusk, Adam A, Jurkute, Neringa, Priglinger, Claudia, Karanjia, Rustum, Josse, Constant, Salzmann, Julie, Montestruc, Françoi, Roux, Michel, Taiel, Magali, Sahel, José-Alain, Carelli, Valerio [0000-0003-4923-6404], Apollo - University of Cambridge Repository

المصدر: OPHTHALMOLOGY AND THERAPY

مصطلحات موضوعية: MT-ND4, Ophthalmology, LHON, Gene therapy, Visual acuity, Medicine and Health Sciences, Natural history, Leber hereditary optic neuropathy

وصف الملف: STAMPA; application/pdf; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407bd2d9bd89577f5a2dd1378b74c5d2
https://hdl.handle.net/11585/916797

المؤلفون: Robert C. Sergott, Gregory P. Van Stavern, Eric R. Eggenberger, Mathew Margolis, Mark L. Moster, Julie Falardeau, Adam A. DeBusk

المصدر: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 41(3)

مصطلحات موضوعية: Adult, Male, Pediatrics, medicine.medical_specialty, Adolescent, Intracranial Pressure, MEDLINE, Spinal Puncture, Young Adult, Cerebrospinal fluid, Neuroimaging, medicine, Humans, Medical diagnosis, Papilledema, Prospective cohort study, Retrospective Studies, Pseudotumor Cerebri, medicine.diagnostic_test, Lumbar puncture, business.industry, Middle Aged, humanities, Ophthalmology, Female, Neurology (clinical), medicine.symptom, business, Body mass index

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510cbdc4993c8586bc0973e66dca5c17
https://pubmed.ncbi.nlm.nih.gov/34369470

المؤلفون: Irena Tsui, Claudia B. Catarino, Piero Barboni, Günther Rudolph, Nancy J. Newman, Sara Silvestri, Alfredo A. Sadun, Michael Dattilo, Neringa Jurkute, Jean-François Girmens, Cosima Schertler, Magali Taiel, Rustum Karanjia, Claudia Priglinger, Maria K Gemenetzi, Armin Wolf, Manuela Contin, Jasmina Al-Tamami, Thomas Klopstock, James Acheson, Robert C. Sergott, Deborah Gibbs, Rabih Hage, Stephan R. Thurau, Adam A. DeBusk, Lidia Di Vito, Mark L. Moster, Valérie Biousse, Med Lindreth DuBois, Valerio Carelli, Gad Heilweil, Chiara La Morgia, Michele Carbonelli, Andrew Hendrick, Patrick Yu-Wai-Man, Jason H. Peragallo, Gerard Smits, Angelika Pressler, Martin Hildebrandt, Alcides Fernandes Filho, Michael Neuenhahn, Bettina von Livonius, Barrett Katz, Daniel R Muth, Siegfried G. Priglinger, Lauren Leitch-Devlin, Susan Mohamed, William R. Tucker, Maria Massini, Maria Eleftheriadou, Laure Blouin, Catherine Vignal-Clermont, Eman Hawy, Simona Degli Esposti, Heather Tollis, G. Baker Hubbard, Jannah Rutter Dobbs, José-Alain Sahel, Catherine Vignal, Melissa SantaMaria, Julie A. Haller

المساهمون: Emory University School of Medicine, Emory University [Atlanta, GA], Addenbrooke's Hospital, Cambridge University NHS Trust, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), University of Bologna, Jefferson (Philadelphia University + Thomas Jefferson University), Fondation Ophtalmologique Adolphe de Rothschild [Paris], Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO), Ludwig-Maximilians-Universität München (LMU), University of California [Los Angeles] (UCLA), University of California, Ludwig Maximilian University [Munich] (LMU), Institut de la Vision, Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Pittsburgh School of Medicine, Pennsylvania Commonwealth System of Higher Education (PCSHE), Institut Hospitalo-Universitaire FOReSIGHT, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO)-Sorbonne Université (SU), Newman, NJ, Yu-Wai-Man, P, Carelli, V, Moster, ML, Biousse, V, Vignal-Clermont, C, Sergott, RC, Klopstock, T, Sadun, AA, Barboni, P, DeBusk, AA, Girmens, JF, Rudolph, G, Karanjia, R, Taiel, M, Blouin, L, Smits, G, Katz, B, Sahel, J-A, Vignal, C, Hage, R, Catarino, CB, Priglinger, C, Priglinger, S, Thurau, S, von Livonius, B, Muth, D, Wolf, A, Al-Tamami, J, Pressler, A, Schertler, C, Hildebrandt, M, Neuenhahn, M, Heilweil, G, Tsui, I, Hubbard, GB, Hendrick, A, Dattilo, M, Peragallo, J, Hawy, E, DuBois, Med L, Gibbs, D, Filho, AF, Dobbs, J, Carbonelli, M, Di Vito, L, Contin, M, Mohamed, S, La Morgia, C, Silvestri, S, Acheson, J, Eleftheriadou, M, Esposti, S, Gemenetzi, M, Leitch-Devlin, L, Tucker, WR, Jurkute, N, SantaMaria, M, Tollis, H, Haller, JA, Massini, M.

المصدر: Ophthalmology: Journal of The American Academy of Ophthalmology
Ophthalmology: Journal of The American Academy of Ophthalmology, Elsevier, 2021, 128 (5), pp.649-660. ⟨10.1016/j.ophtha.2020.12.012⟩
Ophthalmology 128(5), 649-660 (2021). doi:10.1016/j.ophtha.2020.12.012

مصطلحات موضوعية: Male, Time Factors, Visual acuity, genetic structures, physiology [Visual Fields], [SDV]Life Sciences [q-bio], efficacy, Visual Acuity, Phases of clinical research, genetics [Dependovirus], chemistry.chemical_compound, 0302 clinical medicine, Visual Field Test, Quality of life, Clinical endpoint, Contrast (vision), intravitreal gene therapy, media_common, 0303 health sciences, physiology [Visual Acuity], Diabetic retinopathy, Dependovirus, Middle Aged, Dependoviru, genetics [DNA, Mitochondrial], Phase 3 randomized double-masked clinical trial, Treatment Outcome, Intravitreal Injections, diagnosis [Optic Atrophy, Hereditary, Leber], Female, Genetic Vector, medicine.symptom, Human, Adult, safety, LEBER HEREDITARY OPTIC NEUROPATHY, medicine.medical_specialty, retinal anatomic measures, Time Factor, Adolescent, media_common.quotation_subject, psychology [Optic Atrophy, Hereditary, Leber], Genetic Vectors, Visual Field, Humphrey visual field perimetry, Optic Atrophy, Hereditary, Leber, therapy [Optic Atrophy, Hereditary, Leber], DNA, Mitochondrial, bilateral visual improvement, Follow-Up Studie, Leber Hereditary Optic Neuropathy, Young Adult, 03 medical and health sciences, Double-Blind Method, Ophthalmology, psychology [Quality of Life], Electroretinography, medicine, Humans, ddc:610, Aged, 030304 developmental biology, contrast sensitivity, business.industry, Intravitreal Injection, Retinal, Genetic Therapy, retinal anatomic measure, medicine.disease, eye diseases, genetics [Optic Atrophy, Hereditary, Leber], chemistry, Mutation, 030221 ophthalmology & optometry, Visual Field Tests, sense organs, Visual Fields, business, Follow-Up Studies, best-corrected visual acuity

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61639fdbd5cf15223e6676350bc8de96
https://hal.sorbonne-universite.fr/hal-03238444/file/1-s2.0-S0161642020311878-main.pdf

المؤلفون: Larry Frohman, Mark L. Moster, Adam A. DeBusk, Prem S. Subramanian, Molly Scannell Bryan, Preston C. Calvert

المصدر: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 42(1)

مصطلحات موضوعية: medicine.medical_specialty, education.field_of_study, genetic structures, Demographics, Ophthalmologists, business.industry, Time allocation, Population, Psychological intervention, eye diseases, Wait time, United States, Supply and demand, Ophthalmology, Clinical work, Neurology, Family medicine, Physicians, Surveys and Questionnaires, Respondent, Medicine, Humans, Neurology (clinical), business, education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c8c6009aa1d766d07207335cbbd439
https://pubmed.ncbi.nlm.nih.gov/33770009

المؤلفون: Mark L Moster, Robert C Sergott, Nancy J Newman, Patrick Yu-Wai-Man, Valerio Carelli, Molly Scannell Bryan, Gerard Smits, Valérie Biousse, Catherine Vignal-Clermont, Thomas Klopstock, Alfredo A Sadun, Adam A DeBusk, Michele Carbonelli, Rabih Hage, Siegfried Priglinger, Rustum Karanjia, Laure Blouin, Magali Taiel, Barrett Katz, José Alain Sahel, LHON study group

المساهمون: Departments of Neurology and Ophthalmology (MLM, RCS, AAD), Wills Eye Hospital and Thomas Jefferson University, Philadelphia, Pennsylvania, Departments of Ophthalmology (NJN, VB), Neurology and Neurological Surgery, Emory University School of Medicine, Atlanta, Georgia, Cambridge Centre for Brain Repair and MRC Mitochondrial Biology Unit (PY-W-M), Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom, Cambridge Eye Unit (PY-W-M), Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, United Kingdom, Moorfields Eye Hospital (PY-W-M), London, United Kingdom, UCL Institute of Ophthalmology (PY-W-M), University College London, London, United Kingdom, IRCCS Istituto Delle Scienze Neurologiche di Bologna (VC, MC), UOC Clinica Neurologica, Bologna, Italy, Unit of Neurology (VC), Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy, Institute of Health Research and Policy (MSB), University of Illinois, Chicago, Chicago, Illinois, Statistics Consultant (GS), GenSight Biologics, CaliforniaDepartment of Neuro Ophthalmology and Emergencies (CV-C, RH), Rothschild Foundation Hospital, Paris, France, Centre Hospitalier National D'Ophtalmologie des Quinze Vingts (CV-C, RH), Paris, France, Department of Neurology (TK), Friedrich-Baur-Institute, University Hospital, LMU Munich, Munich, Germany, German Center for Neurodegenerative Diseases (DZNE) (TK), Munich, Germany, Munich Cluster for Systems Neurology (SyNergy) (TK), Munich, Germany, Doheny Eye Center UCLA (AAS, RK), Department of Ophthalmology David Geffen School of Medicine at UCLA, Doheny Eye Institute, Los Angeles, CaliforniaDepartment of Ophthalmology (SP), University Hospital, LMU Munich, Munich, Germany, Department of Ophthalmology (RK), University of Ottawa Eye Institute, Ottawa Canada, GenSight Biologics (LB, MT), Paris, France, Medical Consultant (BK), GenSight Biologics, Sorbonne Université (JAS), INSERM, CNRS, Institut de La Vision, 75012 Paris, France, Fondation Ophtalmologique A. de Rothschild (JAS), 25-29 Rue Manin, Paris, Department of Ophthalmology (JAS), the University of Pittsburgh School of Medicine, PittsburghCHNO des Quinze-Vingts (JAS), Institut Hospitalo-Universitaire FOReSIGHT, INSERM-DGOS CIC 1423, Paris, France

المصدر: Journal of Neuro-Ophthalmology, September 2021, Volume 41, Issue 3

Relation: https://collections.lib.utah.edu/ark:/87278/s6m87wdr

الاتاحة: https://collections.lib.utah.edu/ark:/87278/s6m87wdr

المؤلفون: Mathew S Margolis, Adam A DeBusk, Mark L Moster, Julie M Falardeau, Eric R Eggenberger, Robert C Sergott, Gregory P Van Stavern

المساهمون: Department of Ophthalmology and Visual Sciences (MSM), Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois, Department of Ophthalmology and Visual Sciences (GVS), Washington University School of Medicine, St. Louis, Missouri, Department of Neuro-Ophthalmology (AD, MLM, RCS), Wills Eye Hospital, Department of Ophthalmology (JF), Oregon Health and Science University, and Department of Neurology (EE), Mayo Clinic, Jacksonville, Florida

المصدر: Journal of Neuro-Ophthalmology, September 2021, Volume 41, Issue 3

Relation: https://collections.lib.utah.edu/ark:/87278/s607z14t

الاتاحة: https://collections.lib.utah.edu/ark:/87278/s607z14t

المؤلفون: Nancy J. Newman (10860666), Patrick Yu-Wai-Man (410564), Valerio Carelli (24588), Valerie Biousse (9281390), Mark L. Moster (10860669), Catherine Vignal-Clermont (10860672), Robert C. Sergott (10860675), Thomas Klopstock (160225), Alfredo A. Sadun (8108081), Jean-François Girmens (6933603), Chiara La Morgia (24595), Adam A. DeBusk (10860678), Neringa Jurkute (9281408), Claudia Priglinger (10293824), Rustum Karanjia (8108075), Constant Josse (10860681), Julie Salzmann (4167148), François Montestruc (201162), Michel Roux (3762196), Magali Taiel (10860684), José-Alain Sahel (19376)

مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, Leber hereditary optic neuropathy, ND4, gene therapy, natural history, visual acuity

Relation: https://figshare.com/articles/dataset/Data_Sheet_2_Intravitreal_Gene_Therapy_vs_Natural_History_in_Patients_With_Leber_Hereditary_Optic_Neuropathy_Carrying_the_m_11778G_A_ND4_Mutation_Systematic_Review_and_Indirect_Comparison_docx/14659698

الاتاحة: https://doi.org/10.3389/fneur.2021.662838.s002

المؤلفون: Nancy J. Newman (10860666), Patrick Yu-Wai-Man (410564), Valerio Carelli (24588), Valerie Biousse (9281390), Mark L. Moster (10860669), Catherine Vignal-Clermont (10860672), Robert C. Sergott (10860675), Thomas Klopstock (160225), Alfredo A. Sadun (8108081), Jean-François Girmens (6933603), Chiara La Morgia (24595), Adam A. DeBusk (10860678), Neringa Jurkute (9281408), Claudia Priglinger (10293824), Rustum Karanjia (8108075), Constant Josse (10860681), Julie Salzmann (4167148), François Montestruc (201162), Michel Roux (3762196), Magali Taiel (10860684), José-Alain Sahel (19376)

مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, Leber hereditary optic neuropathy, ND4, gene therapy, natural history, visual acuity

Relation: https://figshare.com/articles/dataset/Table_2_Intravitreal_Gene_Therapy_vs_Natural_History_in_Patients_With_Leber_Hereditary_Optic_Neuropathy_Carrying_the_m_11778G_A_ND4_Mutation_Systematic_Review_and_Indirect_Comparison_docx/14659713

الاتاحة: https://doi.org/10.3389/fneur.2021.662838.s007

المؤلفون: Nancy J. Newman (10860666), Patrick Yu-Wai-Man (410564), Valerio Carelli (24588), Valerie Biousse (9281390), Mark L. Moster (10860669), Catherine Vignal-Clermont (10860672), Robert C. Sergott (10860675), Thomas Klopstock (160225), Alfredo A. Sadun (8108081), Jean-François Girmens (6933603), Chiara La Morgia (24595), Adam A. DeBusk (10860678), Neringa Jurkute (9281408), Claudia Priglinger (10293824), Rustum Karanjia (8108075), Constant Josse (10860681), Julie Salzmann (4167148), François Montestruc (201162), Michel Roux (3762196), Magali Taiel (10860684), José-Alain Sahel (19376)

مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, Leber hereditary optic neuropathy, ND4, gene therapy, natural history, visual acuity

Relation: https://figshare.com/articles/figure/Image_1_Intravitreal_Gene_Therapy_vs_Natural_History_in_Patients_With_Leber_Hereditary_Optic_Neuropathy_Carrying_the_m_11778G_A_ND4_Mutation_Systematic_Review_and_Indirect_Comparison_tif/14659701

الاتاحة: https://doi.org/10.3389/fneur.2021.662838.s003

المؤلفون: Adam A. DeBusk, Mark L. Moster

المصدر: Current opinion in ophthalmology. 29(3)

مصطلحات موضوعية: Retinal Ganglion Cells, Gene Modification, Pathology, medicine.medical_specialty, genetic structures, Genetic enhancement, Disease, Optic Atrophy, Hereditary, Leber, Neuroprotection, 03 medical and health sciences, 0302 clinical medicine, Optic Nerve Diseases, Medicine, Animals, Humans, Axon, business.industry, Regeneration (biology), Optic Nerve, General Medicine, Genetic Therapy, eye diseases, Axons, Nerve Regeneration, Ophthalmology, medicine.anatomical_structure, Optic Nerve Injuries, 030221 ophthalmology & optometry, Optic nerve, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef296bab7b8ba4f9b10c226a960b66d
https://pubmed.ncbi.nlm.nih.gov/29538182