نتائج البحث - "Abildgaard, Lea"

1

Academic Journal

Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

المؤلفون: Bentzen, Bo Hjorth, Bomholtz, Sofia Hammami, Simó-Vicens, Rafel, Folkersen, Lasse, Abildgaard, Lea, Speerschneider, Tobias, Muthukumarasamy, Kalai Mangai, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Diness, Jonas Goldin

المصدر: Bentzen , B H , Bomholtz , S H , Simó-Vicens , R , Folkersen , L , Abildgaard , L , Speerschneider , T , Muthukumarasamy , K M , Edvardsson , N , Sørensen , U S , Grunnet , M & Diness , J G 2020 , ' Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man ' , Frontiers in Pharmacology , vol. 11 , 610 . https://doi.org/10.3389/fphar.2020.00610

مصطلحات موضوعية: anti-arrhythmic drugs, atrial fibrillation, ion channels, K2, SK channels

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/mechanisms-of-action-of-the-kca2negative-modulator-ap30663-a-novel-compound-in-development-for-treatment-of-atrial-fibrillation-in-man(4c205ade-2943-4f86-b3a2-5f275970349f).html
https://doi.org/10.3389/fphar.2020.00610
https://curis.ku.dk/ws/files/244567801/OA_Mechanisms_of_Action_of_the_KCa2_Negative_Modulator_AP30663_a_Novel_Compound_in_Development_for_Treatment_of_Atrial_Fibrillation_in_Man.pdf
http://www.scopus.com/inward/record.url?scp=85085759353&partnerID=8YFLogxK

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2

Academic Journal

The K Ca 2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

المؤلفون: Diness, Jonas Goldin, Kirchhoff, Jeppe Egedal, Speerschneider, Tobias, Abildgaard, Lea, Edvardsson, Nils, Sorensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth

المصدر: Diness , J G , Kirchhoff , J E , Speerschneider , T , Abildgaard , L , Edvardsson , N , Sorensen , U S , Grunnet , M & Bentzen , B H 2020 , ' The K Ca 2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs ' , Frontiers in Pharmacology , vol. 11 , 159 . https://doi.org/10.3389/fphar.2020.00159

مصطلحات موضوعية: atrial fibrillation, ion channels, antiarrhythmic drugs, SK channels, K(Ca)2, POTASSIUM SK CHANNELS, HYDROCHLORIDE, VARIANTS, COMMON, LOCI

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/the-kca2-channel-inhibitor-ap30663-selectively-increases-atrial-refractoriness-converts-vernakalantresistant-atrial-fibrillation-and-prevents-its-reinduction-in-conscious-pigs(5caf0664-6a13-4fba-892d-fa7c889b5ada).html
https://doi.org/10.3389/fphar.2020.00159
https://curis.ku.dk/ws/files/247215261/OA_The_K_Ca_2_Channel_Inhibitor_AP30663_Selectively_Increases_Atrial_Refractoriness_Converts_Vernakalant_Resistant_Atrial_Fibrillation_and_Prevents_Its_Reinduction_in_Conscious_Pigs.pdf

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3

Academic Journal

Inhibition of K Ca 2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia

المؤلفون: Diness, Jonas Goldin, Abildgaard, Lea, Bomholtz, Sofia Hammami, Skarsfeldt, Mark Alexander, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth

المصدر: Diness , J G , Abildgaard , L , Bomholtz , S H , Skarsfeldt , M A , Edvardsson , N , Sørensen , U S , Grunnet , M & Bentzen , B H 2020 , ' Inhibition of K Ca 2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia ' , Frontiers in Pharmacology , vol. 11 , 749 . https://doi.org/10.3389/fphar.2020.00749

مصطلحات موضوعية: antiarrhythmic drug, arrhythmia, dofetilide, hypokalemia, K2 channel inhibitor, Kv11.1 blockers, SK channel, SK channel inhibitor

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/inhibition-of-kca2-channels-decreased-the-risk-of-ventricular-arrhythmia-in-the-guinea-pig-heart-during-induced-hypokalemia(c498b9b6-cfdc-480e-8765-5c6fcb21cec6).html
https://doi.org/10.3389/fphar.2020.00749
https://curis.ku.dk/ws/files/244527916/OA_Inhibition_of_K_Ca_2_Channels_Decreased_the_Risk_of_Ventricular_Arrhythmia_in_the_Guinea_Pig_Heart_During_Induced_Hypokalemia.pdf
http://www.scopus.com/inward/record.url?scp=85085898228&partnerID=8YFLogxK

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4

Academic Journal

The K Ca 2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

المؤلفون: Kirchhoff, Jeppe Egedal, Skarsfeldt, Mark, Muthukumarasamy, Kalai Mangai, Simó-Vicens, Rafel, Bomholtz, Sofia Hammami, Abildgaard, Lea, Jespersen, Thomas, Sørensen, Ulrik S, Grunnet, Morten, Bentzen, Bo Hjorth, Diness, Jonas Goldin

المصدر: Kirchhoff , J E , Skarsfeldt , M , Muthukumarasamy , K M , Simó-Vicens , R , Bomholtz , S H , Abildgaard , L , Jespersen , T , Sørensen , U S , Grunnet , M , Bentzen , B H & Diness , J G 2019 , ' The K Ca 2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts ' , Frontiers in Pharmacology , vol. 10 , 668 . https://doi.org/10.3389/fphar.2019.00668

مصطلحات موضوعية: /dk/atira/pure/core/keywords/TheFacultyOfHealthScience, Faculty of Health and Medical Sciences, Arrhythmia, heart rhythm disorders, dofetilide, Ondansetron, AP14145, QT prolongation

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/the-kca2-channel-inhibitor-ap14145-but-not-dofetilide-or-ondansetron-provides-functional-atrial-selectivity-in-guinea-pig-hearts(d2c3f0ef-fe36-4f4b-b5a8-01d7c41678ea).html
https://doi.org/10.3389/fphar.2019.00668
https://curis.ku.dk/ws/files/238539817/OA_FrontierArt.pdf

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5

Academic Journal

A New Negative Allosteric Modulator AP14145 for the Study of Small Conductance Calcium-Activated Potassium Channels

المؤلفون: Simo Vicens, Rafel, Kirchhoff, Jeppe Egedal, Dolce , Bernardo, Abildgaard, Lea, Speerschneider, Tobias, Sørensen, Ulrik Svane, Grunnet, Morten, Diness, Jonas Goldin, Bentzen, Bo Hjorth

المصدر: Simo Vicens , R , Kirchhoff , J E , Dolce , B , Abildgaard , L , Speerschneider , T , Sørensen , U S , Grunnet , M , Diness , J G & Bentzen , B H 2017 , ' A New Negative Allosteric Modulator AP14145 for the Study of Small Conductance Calcium-Activated Potassium Channels ' , British Journal of Pharmacology , vol. 174 , no. 23 , pp. 4396-4408 . https://doi.org/10.1111/bph.14043

مصطلحات موضوعية: /dk/atira/pure/core/keywords/TheFacultyOfHealthScience, Faculty of Health and Medical Sciences, AP14145, Atrial fibrillation, small conductance calcium-activated potassium channels, Electrophysiology, SK channel, negative allosteric modulator

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/a-new-negative-allosteric-modulator-ap14145-for-the-study-of-small-conductance-calciumactivated-potassium-channels(e0f00d5e-e696-49ff-a2e9-a90d4e0786c9).html
https://doi.org/10.1111/bph.14043
https://curis.ku.dk/ws/files/189739966/Post_print_version_for_Green_Open_Access.pdf

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6

Academic Journal

Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

المؤلفون: Kirchhoff, Jeppe Egedal, Diness, Jonas Goldin, Abildgaard, Lea, Sheykhzade, Majid, Grunnet, Morten, Jespersen, Thomas

المصدر: Kirchhoff , J E , Diness , J G , Abildgaard , L , Sheykhzade , M , Grunnet , M & Jespersen , T 2016 , ' Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation ' , Pfluegers Archiv , vol. 468 , no. 11 , pp. 1853–1863 . https://doi.org/10.1007/s00424-016-1883-9

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/antiarrhythmic-effect-of-the-ca2activated-k-sk-channel-inhibitor-ica-combined-with-either-amiodarone-or-dofetilide-in-an-isolated-heart-model-of-atrial-fibrillation(1279209d-96d2-4662-8e82-4ea58e3ccb99).html
https://doi.org/10.1007/s00424-016-1883-9
https://curis.ku.dk/ws/files/171589773/art_3A10.1007_2Fs00424_016_1883_9.pdf

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7

Electronic Resource

The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs

المؤلفون: Diness, Jonas Goldin, Kirchhoff, Jeppe Egedal, Speerschneider, Tobias, Abildgaard, Lea, Edvardsson, Nils, Sorensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth

المصدر: Diness , J G , Kirchhoff , J E , Speerschneider , T , Abildgaard , L , Edvardsson , N , Sorensen , U S , Grunnet , M & Bentzen , B H 2020 , ' The K Ca 2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs ' , Frontiers in Pharmacology , vol. 11 , 159 .

مصطلحات الفهرس: atrial fibrillation, ion channels, antiarrhythmic drugs, SK channels, K(Ca)2, POTASSIUM SK CHANNELS, HYDROCHLORIDE, VARIANTS, COMMON, LOCI, article

URL: https://curis.ku.dk/portal/da/publications/the-kca2-channel-inhibitor-ap30663-selectively-increases-atrial-refractoriness-converts-vernakalantresistant-atrial-fibrillation-and-prevents-its-reinduction-in-conscious-pigs(5caf0664-6a13-4fba-892d-fa7c889b5ada).html
https://doi.org/10.3389/fphar.2020.00159
https://curis.ku.dk/ws/files/247215261/OA_The_K_Ca_2_Channel_Inhibitor_AP30663_Selectively_Increases_Atrial_Refractoriness_Converts_Vernakalant_Resistant_Atrial_Fibrillation_and_Prevents_Its_Reinduction_in_Conscious_Pigs.pdf

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8

Electronic Resource

Inhibition of KCa2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia

المؤلفون: Diness, Jonas Goldin, Abildgaard, Lea, Bomholtz, Sofia Hammami, Skarsfeldt, Mark Alexander, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth

المصدر: Diness , J G , Abildgaard , L , Bomholtz , S H , Skarsfeldt , M A , Edvardsson , N , Sørensen , U S , Grunnet , M & Bentzen , B H 2020 , ' Inhibition of K Ca 2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia ' , Frontiers in Pharmacology , vol. 11 , 749 .

مصطلحات الفهرس: antiarrhythmic drug, arrhythmia, dofetilide, hypokalemia, K2 channel inhibitor, Kv11.1 blockers, SK channel, SK channel inhibitor, article

URL: https://curis.ku.dk/portal/da/publications/inhibition-of-kca2-channels-decreased-the-risk-of-ventricular-arrhythmia-in-the-guinea-pig-heart-during-induced-hypokalemia(c498b9b6-cfdc-480e-8765-5c6fcb21cec6).html
https://doi.org/10.3389/fphar.2020.00749
https://curis.ku.dk/ws/files/244527916/OA_Inhibition_of_K_Ca_2_Channels_Decreased_the_Risk_of_Ventricular_Arrhythmia_in_the_Guinea_Pig_Heart_During_Induced_Hypokalemia.pdf
http://www.scopus.com/inward/record.url?scp=85085898228&partnerID=8YFLogxK

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9

Electronic Resource

The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

المؤلفون: Kirchhoff, Jeppe Egedal, Skarsfeldt, Mark, Muthukumarasamy, Kalai Mangai, Simó-Vicens, Rafel, Bomholtz, Sofia Hammami, Abildgaard, Lea, Jespersen, Thomas, Sørensen, Ulrik S, Grunnet, Morten, Bentzen, Bo Hjorth, Diness, Jonas Goldin

المصدر: Kirchhoff , J E , Skarsfeldt , M , Muthukumarasamy , K M , Simó-Vicens , R , Bomholtz , S H , Abildgaard , L , Jespersen , T , Sørensen , U S , Grunnet , M , Bentzen , B H & Diness , J G 2019 , ' The K Ca 2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts ' , Frontiers in Pharmacology , vol. 10 , 668 .

مصطلحات الفهرس: dk/atira/pure/core/keywords/TheFacultyOfHealthScience, Faculty of Health and Medical Sciences, Arrhythmia, heart rhythm disorders, dofetilide, Ondansetron, AP14145, QT prolongation, article

URL: https://curis.ku.dk/portal/da/publications/the-kca2-channel-inhibitor-ap14145-but-not-dofetilide-or-ondansetron-provides-functional-atrial-selectivity-in-guinea-pig-hearts(d2c3f0ef-fe36-4f4b-b5a8-01d7c41678ea).html
https://doi.org/10.3389/fphar.2019.00668
https://curis.ku.dk/ws/files/238539817/OA_FrontierArt.pdf

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10

Academic Journal

Inhibition of KCa2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia.

المؤلفون: Diness, Jonas Goldin, Abildgaard, Lea, Bomholtz, Sofia Hammami, Skarsfeldt, Mark Alexander, Edvardsson, Nils, Sørensen, Ulrik S., Grunnet, Morten, Bentzen, Bo Hjorth

المصدر: Frontiers in Pharmacology; 5/20/2020, p1-10, 10p

مصطلحات موضوعية: HYPOKALEMIA, GUINEA pigs, VENTRICULAR arrhythmia, VENTRICULAR fibrillation, HEART beat, ATRIAL fibrillation

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11

Academic Journal

pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

المؤلفون: Skarsfeldt, Mark A, Jepps, Thomas A, Bomholtz, Sofia H, Abildgaard, Lea, Sørensen, Ulrik S, Gregers, Emilie, Svendsen, Jesper H, Diness, Jonas G, Grunnet, Morten, Schmitt, Nicole, Olesen, Søren-Peter, Bentzen, Bo H

المصدر: Skarsfeldt , M A , Jepps , T A , Bomholtz , S H , Abildgaard , L , Sørensen , U S , Gregers , E , Svendsen , J H , Diness , J G , Grunnet , M , Schmitt , N , Olesen , S-P & Bentzen , B H 2016 , ' pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts ' , Pfluegers Archiv , vol. 468 , no. 4 , pp. 643-654 . https://doi.org/10.1007/s00424-015-1779-0

الاتاحة: https://curis.ku.dk/portal/da/publications/phdependent-inhibition-of-k2p31-prolongs-atrial-refractoriness-in-whole-hearts(beb60303-3180-4b12-aed2-f3c691ef2469).html
https://doi.org/10.1007/s00424-015-1779-0

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