المؤلفون: Hongjian Qin, Zijian Han, Emmanuel Mintah Bonku, Haiguo Sun, Abdullajon Odilov, Fuqiang Zhu, Safomuddin Abduahadi, Weiliang Zhu, Jingshan Shen, Haji A. Aisa

المصدر: Communications Chemistry, Vol 7, Iss 1, Pp 1-9 (2024)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3669

URL الوصول: https://doaj.org/article/2d0296056171457d831e32f0f08b6e31

المؤلفون: Emmanuel Mintah Bonku, Hongjian Qin, Abdullajon Odilov, Safomuddin Abduahadi, Samuel Desta Guma, Feipu Yang, Xinglong Xing, Xukun Wang, Jingshan Shen

المصدر: Heliyon, Vol 10, Iss 9, Pp e29559- (2024)

مصطلحات موضوعية: Tecovirimat, Genotoxic impurities, Process development, International Conference on Harmonization (ICH), Quality control, Science (General), Q1-390, Social sciences (General), H1-99

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024055907; https://doaj.org/toc/2405-8440

URL الوصول: https://doaj.org/article/9fe4477831ed46f093e9e3d4841dd56e

المؤلفون: Hongjian Qin (5180876), Chen Jin (703369), Abdullajon Odilov (11579917), Emmanuel Mintah Bonku (14284805), Fuqiang Zhu (2937369), Qi Liu (33068), Jingshan Shen (1601962), Haji A. Aisa (8269605)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, pot raney nickel, performance liquid chromatography, improved synthetic efficiency, concise alternative process, three steps, subsequent deprotection, overall yield, n <, key intermediate, cyano group, concomitant cyclization, catalyzed hydrogenation, >- bocglu, >- boc

Relation: https://figshare.com/articles/journal_contribution/Optimized_Synthesis_of_a_Key_Intermediate_of_Nirmatrelvir/21758657

الاتاحة: https://doi.org/10.1021/acs.oprd.2c00225.s001

المؤلفون: Wanbin Xu (8269602), Xudong Gong (6680201), Abdullajon Odilov (11579917), Tianwen Hu (3278730), Xiangrui Jiang (1601968), Fuqiang Zhu (2937369), Shuang Guo (294074), Dehui Jiang (1617592), Mingjun Wu (1807558), Jingshan Shen (1601962)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Immunology, Plant Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, key starting material, high total yield, 19 , 1 , overall yield, triphenylmethyl chloride, three steps, target compound, secondary amine, scalable process, route includes, protecting group, hplc purity, formaldehyde instead, following features, dichlorobenzoyl chloride, 76 %

Relation: https://figshare.com/articles/journal_contribution/Scalable_Process_for_Making_5_7-Dichlorotetrahydroisoquinoline-6-carboxylic_Acid_Using_Methylene_as_the_Protecting_Group/16831594

الاتاحة: https://doi.org/10.1021/acs.oprd.1c00229.s001

المؤلفون: Abdullajon Odilov (11579917), Yin Liu (50073), Tianwen Hu (3278730), Xiangrui Jiang (1601968), Jin Suo (2012833), Guanghui Tian (2012824), Feipu Yang (2937366), Jingshan Shen (1601962)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Pharmacology, Biotechnology, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, potent pde5 inhibitor, key intermediate 2, propoxybenzimidamide (< b, 21 , subsequent process, pyrimidinone derivatives, potential precursor, overall yield, effective route, conveniently obtained, clinical candidate

Relation: https://figshare.com/articles/journal_contribution/Facile_and_Cost-Effective_Route_for_the_Synthesis_of_Simmerafil/16832450

الاتاحة: https://doi.org/10.1021/acs.oprd.1c00184.s001

المؤلفون: Hongjian Qin, Chen Jin, Abdullajon Odilov, Emmanuel Mintah Bonku, Fuqiang Zhu, Qi Liu, Jingshan Shen, Haji A. Aisa

المصدر: Organic Process Research & Development. 27:78-83

مصطلحات موضوعية: Organic Chemistry, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::826839b9c0602a846e8166d20cabf433
https://doi.org/10.1021/acs.oprd.2c00225

المؤلفون: Hongjian Qin, Abdullajon Odilov, Emmanuel Mintah Bonku, Fuqiang Zhu, Tianwen Hu, He Liu, Haji A. Aisa, Jingshan Shen

المصدر: ACS Omega. 7:45678-45687

مصطلحات موضوعية: General Chemical Engineering, General Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::550fcc8a5dc64edfbef99c94666010f2
https://doi.org/10.1021/acsomega.2c06554

المؤلفون: Tianwen Hu, Abdullajon Odilov, Guanghui Tian, Jingshan Shen, Feipu Yang, Jin Suo, Yin Liu, Xiangrui Jiang

المصدر: Organic Process Research & Development. 25:2432-2437

مصطلحات موضوعية: Chemistry, Organic Chemistry, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::64a3cf84f84b54ee5ea2cad4c2064fa2
https://doi.org/10.1021/acs.oprd.1c00184

المؤلفون: Shuang Guo, Xudong Gong, Abdullajon Odilov, Fuqiang Zhu, Tianwen Hu, Dehui Jiang, Xiangrui Jiang, Wanbin Xu, Jingshan Shen, Mingjun Wu

المصدر: Organic Process Research & Development. 25:2447-2452

مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Lifitegrast, chemistry, Process (engineering), Carboxylic acid, Organic Chemistry, Scalability, Key (cryptography), Physical and Theoretical Chemistry, Methylene, Protecting group, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2510880251527ac873d71791d4c7ab40
https://doi.org/10.1021/acs.oprd.1c00229

المؤلفون: Yi-Fei, He, Yin, Liu, Jing-Hua, Yu, Huan, Cheng, Abdullajon, Odilov, Fei-Pu, Yang, Guang-Hui, Tian, Xiu-Mei, Yao, Hua-Qing, Duan, Cheng-Yin, Yu, Chen, Yu, Yan-Mei, Liu, Gang-Yi, Liu, Jing-Shan, Shen, Zhen, Wang, Xing-Xing, Diao

المصدر: Acta pharmacologica Sinica. 44(1)

مصطلحات موضوعية: Male, Pulmonary Arterial Hypertension, Feces, Humans, Administration, Oral, Pyrimidinones, Phosphodiesterase 5 Inhibitors, Biotransformation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::444e682cb4be9ddc0890ddbdb971121b
https://pubmed.ncbi.nlm.nih.gov/35676531

المؤلفون: Hongjian Qin, Emmanuel Mintah Bonku, Abdullajon Odilov, Mingjun Wu, Yongjian Liu, Jingshan Shen, Fuqiang Zhu, Haji A. Aisa

مصطلحات موضوعية: Biochemistry, Medicine, Biotechnology, Ecology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, developed process provides, alternative sustainable route, >‑ butyronitrile herein, isolated yield using, 5 , 11 , 10 , sustainable synthesis method, final step via, achieve high yields, isolated yield via, 2 ‑ bromoarylamine, isolated yield, n <, reaction step, completed via, >- butyronitrile, telmisartan via, sulfuric acid, starting materials, pot reduction, polyphosphoric acid

Relation: https://figshare.com/articles/journal_contribution/Optimized_Synthesis_of_the_Key_Intermediate_of_Telmisartan_via_the_Cyclization_of_2_Bromoarylamine_with_i_n_i_Butyronitrile/24512490

الاتاحة: https://doi.org/10.1021/acs.oprd.3c00298.s001
https://figshare.com/articles/journal_contribution/Optimized_Synthesis_of_the_Key_Intermediate_of_Telmisartan_via_the_Cyclization_of_2_Bromoarylamine_with_i_n_i_Butyronitrile/24512490