نتائج البحث - "Abbie Wong"

1

Supplementary Tables and Figures from Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody–Drug Conjugates

المؤلفون: Peter D. Senter, Robert P. Lyon, Weiping Zeng, Margo C. Zaval, Abbie Wong, Andrew B. Waight, Michelle L. Ulrich, Jessica K. Simmons, Paul G. Pittman, Jay C. Nix, Jason Neale, David W. Meyer, Luke V. Loftus, Fu Li, Steven Jin, Julia H. Cochran, Martha E. Anderson, Kathleen C. Olivas, Christopher S. Neumann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db82a176dff235f814043a7bfa28d04
https://doi.org/10.1158/1535-7163.22505812

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2

Supplementary Methods from Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody–Drug Conjugates

المؤلفون: Peter D. Senter, Robert P. Lyon, Weiping Zeng, Margo C. Zaval, Abbie Wong, Andrew B. Waight, Michelle L. Ulrich, Jessica K. Simmons, Paul G. Pittman, Jay C. Nix, Jason Neale, David W. Meyer, Luke V. Loftus, Fu Li, Steven Jin, Julia H. Cochran, Martha E. Anderson, Kathleen C. Olivas, Christopher S. Neumann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916122efb9c585694b4a5165b3263a57
https://doi.org/10.1158/1535-7163.22505815

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3

Data from Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody–Drug Conjugates

المؤلفون: Peter D. Senter, Robert P. Lyon, Weiping Zeng, Margo C. Zaval, Abbie Wong, Andrew B. Waight, Michelle L. Ulrich, Jessica K. Simmons, Paul G. Pittman, Jay C. Nix, Jason Neale, David W. Meyer, Luke V. Loftus, Fu Li, Steven Jin, Julia H. Cochran, Martha E. Anderson, Kathleen C. Olivas, Christopher S. Neumann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::573a206071ce06934ff2470390402a2e
https://doi.org/10.1158/1535-7163.c.6538195.v1

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4

1357 Reversible chemical modulation of antibody effector function maintains anti-tumor activity while mitigating peripheral immune activation

المؤلفون: Matthew Levengood, Chris Leiske, Noah Bindman, Xinqun Zhang, Nicole Duncan, Weiping Zeng, Serena Wo, Abbie Wong, Clark Henderson, Karalyne Crowder, Haley Neff-LaFord, Django Sussman, Shyra Gardai, Philip Moquist

المصدر: Regular and Young Investigator Award Abstracts.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ca16c591e415cb65eb959c058004bae0
https://doi.org/10.1136/jitc-2022-sitc2022.1357

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5

Abstract LB246: Enfortumab vedotin, a nectin-4-directed antibody-drug conjugate, demonstrates compelling antitumor activity in non-muscle invasive bladder cancer models which predicts minimal systemic exposure when administered by intravesical instillation in patients

المؤلفون: Devra Olson, Yen Lin Chia, Enaharo Iboi, Lauren Farr, Maddy Burcher, Anthony Lee, Kelly Hensley, Sean Allred, Abbie Wong, Masashi Shimazaki, Masamichi Mori, Sharsti Sandall, Christopher Carosino

المصدر: Cancer Research. 83:LB246-LB246

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7ecbc389645028849f7d4c6fea700789
https://doi.org/10.1158/1538-7445.am2023-lb246

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6

An in Vitro Assay Using Cultured Kupffer Cells Can Predict the Impact of Drug Conjugation on in Vivo Antibody Pharmacokinetics

المؤلفون: David W. Meyer, Mechthild Jonas, Serena W. Wo, Joshua H. Hunter, Martha Anderson, Joe Z Hamilton, Lauren Bou, Sara Shum, Robert P. Lyon, Nicole M. Okeley, Abbie Wong

المصدر: Molecular pharmaceutics. 17(3)

مصطلحات موضوعية: Biodistribution, Immunoconjugates, medicine.drug_class, Cell Survival, Kupffer Cells, Metabolic Clearance Rate, Surface Properties, Cell Culture Techniques, Pharmaceutical Science, 02 engineering and technology, Pharmacology, Monoclonal antibody, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, In vivo, Bone Marrow, Drug Discovery, medicine, Animals, Humans, Tissue Distribution, Cells, Cultured, biology, Chemistry, Antibodies, Monoclonal, 021001 nanoscience & nanotechnology, In vitro, Rats, body regions, Liver, Drug Design, Injections, Intravenous, biology.protein, PEGylation, Molecular Medicine, Female, Animal studies, Antibody, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d9b798b9be6fc75511535ab7292e0a
https://pubmed.ncbi.nlm.nih.gov/31976667

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7

Abstract 2888: Utilizing PDX models to better understand factors that predict response to SGN-CD228A, an antibody drug-conjugate (ADC) for solid tumors

المؤلفون: Robert Lawrence, Kelly Hensley, Christopher Hale, John Gosink, Sean Allred, David Ortiz, Rachael Hu, Christine O'Day, Phillip M. Garfin, Timothy S. Lewis, Marsha Mason, Sharsti Sandall, Scott Peterson, Rebecca Mazahreh, Abbie Wong

المصدر: Cancer Research. 80:2888-2888

مصطلحات موضوعية: Cancer Research, Tumor microenvironment, Colorectal cancer, business.industry, Melanoma, Cancer, medicine.disease, Breast cancer, Oncology, Pancreatic cancer, medicine, Cancer research, Biomarker (medicine), Mesothelioma, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::33084f2cd650c356fda33dced9def7a6
https://doi.org/10.1158/1538-7445.am2020-2888

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8

Targeted Delivery of Cytotoxic NAMPT Inhibitors Using Antibody-Drug Conjugates

المؤلفون: Julia H. Cochran, Paul G. Pittman, Steven Jin, Robert P. Lyon, Michelle Ulrich, Martha Anderson, Fu Li, Abbie Wong, Luke V. Loftus, Margo Zaval, Jay C. Nix, Jason Neale, Peter D. Senter, David W. Meyer, Jessica K. Simmons, Weiping Zeng, Andrew B. Waight, Christopher Scott Neumann, Kathleen C. Olivas

المصدر: Molecular cancer therapeutics. 17(12)

مصطلحات موضوعية: 0301 basic medicine, Drug, Cancer Research, Immunoconjugates, media_common.quotation_subject, Cell, Nicotinamide phosphoribosyltransferase, Mice, SCID, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Drug Delivery Systems, Cell Line, Tumor, medicine, Cytotoxic T cell, Structure–activity relationship, Animals, Humans, Enzyme Inhibitors, Nicotinamide Phosphoribosyltransferase, media_common, chemistry.chemical_classification, Cell Death, Xenograft Model Antitumor Assays, body regions, 030104 developmental biology, medicine.anatomical_structure, Enzyme, Oncology, chemistry, Cancer cell, Cancer research, Female, NAD+ kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3e4e7f3cada75f5ac91f4c7c022d8a
https://pubmed.ncbi.nlm.nih.gov/30242091

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9

Abstract 983: Antibody-drug conjugates of NAMPT inhibitors: Discovery, optimization, and preclinical characterization

المؤلفون: Michelle Ulrich, Steven Jin, Jessica K. Simmons, Fu Li, Robert P. Lyon, Abbie Wong, Weiping Zeng, Julia H. Cochran, Kung Pern Wang, Andrew B. Waight, Paul G. Pittman, David W. Meyer, Chris Neumann, Martha Anderson, Margo Zaval, Peter D. Senter, Kathleen C. Olivas, Luke V. Loftus

المصدر: Cancer Research. 79:983-983

مصطلحات موضوعية: Drug, Cancer Research, Nicotinamide, Chemistry, media_common.quotation_subject, Nicotinamide phosphoribosyltransferase, Small molecule, In vitro, chemistry.chemical_compound, Oncology, In vivo, Cancer research, NAD+ kinase, Linker, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4619283e04f0c23f9c6b7da4df33e659
https://doi.org/10.1158/1538-7445.am2019-983

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