المؤلفون: Milica Markovic, Shimon Ben-Shabat, Jagadeesh Nagendra Manda, Karina Abramov-Harpaz, Clil Regev, Yifat Miller, Aaron Aponick, Ellen M. Zimmermann, Arik Dahan

المصدر: Pharmaceutics, Vol 14, Iss 3, p 675 (2022)

مصطلحات موضوعية: inflammatory bowel disease, drug targeting, oral drug delivery, prodrug, cyclosporine, phospholipase A2, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/3/675; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/ce2b19224b9c4189b6e40db9f106c9c1

المؤلفون: Milica Markovic, Arik Dahan, Shahar Keinan, Igor Kurnikov, Aaron Aponick, Ellen M. Zimmermann, Shimon Ben-Shabat

المصدر: Pharmaceutics, Vol 11, Iss 4, p 186 (2019)

مصطلحات موضوعية: colon-targeted drug delivery, prodrug approach, ulcerative colitis, Phospholipase A2, molecular dynamics, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/11/4/186; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/0734b4e8dd724241922c49c56ed02805

المؤلفون: Berenger Biannic, Thomas Ghebreghiorgis, Aaron Aponick

المصدر: Beilstein Journal of Organic Chemistry, Vol 7, Iss 1, Pp 802-807 (2011)

مصطلحات موضوعية: allylic alcohol, allylic ether, Au-catalyzed, SN2', tetrahydropyran, Science, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1860-5397

URL الوصول: https://doaj.org/article/8d4e807e7c79470f907fbf8b6fe7e2a3

المؤلفون: Milica Markovic, Shimon Ben-Shabat, Shahar Keinan, Aaron Aponick, Ellen M. Zimmermann, Arik Dahan

المصدر: Pharmaceutics, Vol 10, Iss 4, p 210 (2018)

مصطلحات موضوعية: drug delivery, drug therapy, phospholipids, prodrugs, PLA2, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4923/10/4/210; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/b26019c9497d45eebe92c7dad65f9b63

المؤلفون: Shengkang Yin, Kendall N. Weeks, Aaron Aponick

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Biotechnology, Ecology, Immunology, Developmental Biology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optically active nitrogen, including chiral hydroxylamines, chiral propargylic alcohols, >- hydroxylamines via, chiral propargyl, >- ligands, wide range, simple cu, reaction products, reaction accommodates, p <, first cu, facile transformations, established method, diverse array, containing compounds, catalyzed protocol, accessed directly

Relation: https://figshare.com/articles/journal_contribution/Catalytic_Enantioselective_Alkyne_Addition_to_Nitrones_Enabled_by_Tunable_Axially_Chiral_Imidazole-Based_P_N-Ligands/25355464

الاتاحة: https://doi.org/10.1021/jacs.4c00873.s001
https://figshare.com/articles/journal_contribution/Catalytic_Enantioselective_Alkyne_Addition_to_Nitrones_Enabled_by_Tunable_Axially_Chiral_Imidazole-Based_P_N-Ligands/25355464

المؤلفون: Shengkang Yin, Ji Liu, Kendall N. Weeks, Aaron Aponick

مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Sociology, Immunology, Developmental Biology, Space Science, Chemical Sciences not elsewhere classified, selective racemate crystallization, near optical purity, method also enables, membered heterobiaryls synthesized, enables rapid access, efficiently integrates π, new chiral non, catalytic enantioselective synthesis, axially chiral imidazoles, stable axial configuration, stable configuration, chiral axis, highly enantioselective, bearing imidazoles, stacking moieties, ortho position, operationally simple, interestingly even, high yield

Relation: https://figshare.com/articles/journal_contribution/Catalytic_Enantioselective_Synthesis_of_Axially_Chiral_Imidazoles_by_Cation-Directed_Desymmetrization/24813701

الاتاحة: https://doi.org/10.1021/jacs.3c10746.s001
https://figshare.com/articles/journal_contribution/Catalytic_Enantioselective_Synthesis_of_Axially_Chiral_Imidazoles_by_Cation-Directed_Desymmetrization/24813701

المؤلفون: Milica Markovic, Karina Abramov-Harpaz, Clil Regev, Shimon Ben-Shabat, Aaron Aponick, Ellen M. Zimmermann, Yifat Miller, Arik Dahan

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2673

مصطلحات موضوعية: inflammatory bowel disease, drug targeting, oral drug delivery, prodrug, cyclosporine, phospholipase A 2

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Informatics; https://dx.doi.org/10.3390/ijms23052673

الاتاحة: https://doi.org/10.3390/ijms23052673

المؤلفون: Ji Liu (110659), Edward M. Laguna (1712902), Arun Raj Kizhakkayil Mangadan (11766602), Kyoungmin Kang (4242856), Aaron Aponick (1409662)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Molecular Biology, Biotechnology, Space Science, Chemical Sciences not elsewhere classified, transformation proceeds via, short enantioselective synthesis, intermolecular enantioselective palladium, enables direct access, catalyzed decarboxylative allylation, sphere process proposed, sphere mechanism, years ago, traditional outer, simple procedure, makes use, highly useful, experiments suggest, coupling substrates, allyl carbonates, (+)- adalinine

Relation: https://figshare.com/articles/journal_contribution/The_Enantioselective_Intermolecular_Saegusa_Allylation/17092058

الاتاحة: https://doi.org/10.1021/acscatal.1c04546.s001

المؤلفون: Milica Markovic, Shimon Ben-Shabat, Aaron Aponick, Ellen M. Zimmermann, Arik Dahan

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 9; Pages: 3248

مصطلحات موضوعية: lipid, fatty acid, glyceride, steroid, phospholipid, oral drug absorption, prodrug, phospholipase A 2 (PLA 2 )

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Endocrinology and Metabolism; https://dx.doi.org/10.3390/ijms21093248

الاتاحة: https://doi.org/10.3390/ijms21093248

المؤلفون: Milica Markovic, Shimon Ben-Shabat, Shahar Keinan, Aaron Aponick, Ellen M. Zimmermann, Arik Dahan

المصدر: International Journal of Molecular Sciences; Volume 20; Issue 9; Pages: 2210

مصطلحات موضوعية: drug delivery, prodrugs, phospholipid, phospholipase A2, in-silico, molecular docking, molecular dynamics, molecular biopharmaceutics

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Informatics; https://dx.doi.org/10.3390/ijms20092210

الاتاحة: https://doi.org/10.3390/ijms20092210

المؤلفون: Aaron Aponick, Gaurav Dahiya, Khalil A. Abboud

المصدر: Synthesis. 54:2157-2164

مصطلحات موضوعية: Organic Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::480b5c25b5892bb4c0ee8d05afdc8db2
https://doi.org/10.1055/a-1730-2473

المؤلفون: Ji Liu, Aaron Aponick, Kyoungmin Kang, Arun Raj Kizhakkayil Mangadan, Edward M. Laguna

المصدر: ACS Catalysis. 11:14842-14847

مصطلحات موضوعية: Chemistry, Computational chemistry, Decarboxylation, Intermolecular force, Enantioselective synthesis, Homogeneous catalysis, General Chemistry, Catalysis, Stoichiometry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::96197dab1f533b801664146ec412d552
https://doi.org/10.1021/acscatal.1c04546

المؤلفون: Ji Liu, Arun Raj Kizhakkayil Mangadan, Aaron Aponick

المصدر: Angewandte Chemie. 133:22398-22403

مصطلحات موضوعية: Allylic rearrangement, Alkylation, Molecular Structure, Chemistry, Ligand, Stereochemistry, Leaving group, Enantioselective synthesis, Stereoisomerism, General Chemistry, General Medicine, Hydrogen-Ion Concentration, Ligands, Catalysis, Allyl Compounds, Tsuji–Trost reaction, chemistry.chemical_compound, Lactones, Imidazole, Racemization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12cde43a0f9f8c4227b3136e9cba2de2
https://doi.org/10.1002/ange.202108336

المؤلفون: Shimon Ben-Shabat, Aaron Aponick, Ellen M. Zimmermann, Jagadeesh Nagendra Manda, Milica Markovic, Arik Dahan

المصدر: ChemMedChem. 15:1639-1644

مصطلحات موضوعية: Drug, media_common.quotation_subject, Phospholipid, Inflammation, Pharmacology, 01 natural sciences, Biochemistry, Inflammatory bowel disease, Structure-Activity Relationship, chemistry.chemical_compound, Phospholipase A2, Drug Discovery, medicine, Humans, Prodrugs, General Pharmacology, Toxicology and Pharmaceutics, Phospholipids, media_common, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Activator (genetics), Hydrolysis, Organic Chemistry, Prodrug, Inflammatory Bowel Diseases, medicine.disease, In vitro, 0104 chemical sciences, Phospholipases A2, 010404 medicinal & biomolecular chemistry, Drug Design, Cyclosporine, biology.protein, Molecular Medicine, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2935b9ceb075a3775cf5cc846c5c83
https://doi.org/10.1002/cmdc.202000317

المؤلفون: Milica, Markovic, Shimon, Ben-Shabat, Jagadeesh, Nagendra Manda, Karina, Abramov-Harpaz, Clil, Regev, Yifat, Miller, Aaron, Aponick, Ellen M, Zimmermann, Arik, Dahan

المصدر: Pharmaceutics. 14(3)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c2ca72ae600894a782c8468c35d242c3
https://pubmed.ncbi.nlm.nih.gov/35336048

المؤلفون: Milica, Markovic, Karina, Abramov-Harpaz, Clil, Regev, Shimon, Ben-Shabat, Aaron, Aponick, Ellen M, Zimmermann, Yifat, Miller, Arik, Dahan

المصدر: International journal of molecular sciences. 23(5)

مصطلحات موضوعية: Phospholipases A2, Cyclosporine, Humans, Prodrugs, Inflammatory Bowel Diseases, Phospholipids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c11afccdab1a2599a4e9483ddb566986
https://pubmed.ncbi.nlm.nih.gov/35269813

المؤلفون: Aaron Aponick, Sourabh Mishra

المصدر: Angewandte Chemie. 131:9585-9590

مصطلحات موضوعية: chemistry.chemical_classification, Molecular Structure, 010405 organic chemistry, Decarboxylation, Enantioselective synthesis, Regioselectivity, Alkyne, Stereoisomerism, General Chemistry, General Medicine, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, Catalysis, Cycloaddition, 0104 chemical sciences, Lactones, chemistry, Nucleophile, Electrophile

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bc61a0a364969e19de74b10eb1f4ec
https://doi.org/10.1002/ange.201904438

المؤلفون: Gaurav Dahiya, Aaron Aponick, Mukesh Pappoppula

المصدر: Angewandte Chemie (International ed. in English). 60(36)

مصطلحات موضوعية: Steric effects, Atropisomer, Chemistry, Stereochemistry, Enantioselective synthesis, General Chemistry, Systematic variation, General Medicine, Borylation, Catalysis, Incremental change

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d39e3ce77b149f9ab8cfb5d3c91469f
https://pubmed.ncbi.nlm.nih.gov/34196080

المؤلفون: Jagadeesh Nagendra Manda, Barry B. Butler, Aaron Aponick

المصدر: The Journal of organic chemistry. 85(21)

مصطلحات موضوعية: biology, Molecular Structure, Stereochemistry, Longest linear sequence, Organic Chemistry, Convergent synthesis, Regioselectivity, Stereoisomerism, Tetrahydropyran, Protein phosphatase 2, Enzyme assay, chemistry.chemical_compound, chemistry, Cyclization, biology.protein, Spiro Compounds, Macrolides, Southern Hemisphere, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8563feb0439185ca1febc3202d917e71
https://pubmed.ncbi.nlm.nih.gov/33111529

المؤلفون: Shimon Ben-Shabat, Ellen M. Zimmermann, Arik Dahan, Aaron Aponick, Milica Markovic

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 3248, p 3248 (2020)
International Journal of Molecular Sciences

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Pharmacology, lcsh:Chemistry, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, phospholipase A2 (PLA2), lcsh:QH301-705.5, Spectroscopy, media_common, Drug Carriers, glyceride, steroid, Concept Paper, General Medicine, Prodrug, Lipids, Computer Science Applications, 030220 oncology & carcinogenesis, Drug delivery, lipids (amino acids, peptides, and proteins), prodrug, Metabolic Networks and Pathways, Drug, media_common.quotation_subject, Phospholipid, Context (language use), Catalysis, Steroid, Inorganic Chemistry, Structure-Activity Relationship, 03 medical and health sciences, lipid, medicine, Animals, Humans, Physical and Theoretical Chemistry, Molecular Biology, phospholipid, business.industry, Organic Chemistry, Lipid Metabolism, Bioavailability, oral drug absorption, Drug Liberation, 030104 developmental biology, Solubility, chemistry, Targeted drug delivery, lcsh:Biology (General), lcsh:QD1-999, fatty acid, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa79270974080208a81af699faa58fd
https://www.mdpi.com/1422-0067/21/9/3248