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المؤلفون: Christina Falkeis-Veits, Victoria Neumeyer, Elisabeth Kremmer, Anna Brutau-Abia, Nicole Pfarr, Michael Allgäuer, Raquel Mejías-Luque, Markus Gerhard, Wilko Weichert, Michael Vieth
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cell. Mol. Gast. Hept. 11, 1071-1094 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1071-1094 (2021)مصطلحات موضوعية: 0301 basic medicine, Male, ATR, ATM-and Rad3-Related, MSI-high, microsatellite instability-high, Carcinogenesis, RNP, ribonucleoprotein, Apoptosis, medicine.disease_cause, Mice, 0302 clinical medicine, Tumor Cells, Cultured, RNF43, RING finger protein 43, PMSS1, pre-mouse SS1, Wnt Signaling Pathway, Original Research, Aged, 80 and over, Mice, Knockout, Mutation, Stomach, Gastroenterology, Wnt signaling pathway, CHK, checkpoint kinase, Middle Aged, Dna Damage Response (ddr), Gastric Cancer, Helicobacter Pylori, Rnf43, ddc, medicine.anatomical_structure, Editorial, Gastritis, RNF43, GC, gastric cancer, 030211 gastroenterology & hepatology, Female, SNP, single-nucleotide polymorphism, medicine.drug, Adult, MSI, microsatellite unstable, SDS, sodium dodecyl sulfate, DNA damage, Ubiquitin-Protein Ligases, H2AX, H2A histone family member X, WNT, Wingless-related integration site, Biology, DDR, DNA damage response, Helicobacter Infections, 03 medical and health sciences, Stomach Neoplasms, medicine, Animals, Humans, DSB, double-strand break, Viability assay, lcsh:RC799-869, Aged, Cell Proliferation, Cisplatin, Hepatology, Helicobacter pylori, D196, deletion at aspartic acid 196, DNA Damage Response (DDR), ATM, ataxia-telangiectasia mutated, shControl, short hairpin control, biology.organism_classification, Xenograft Model Antitumor Assays, WT, wild-type, CRISPR/Cas9, Clustered related interspaced short palindromic repeats/CRISPR associated 9, Mice, Inbred C57BL, body regions, 030104 developmental biology, Case-Control Studies, shRNF43, short hairpin RING finger protein 43, Cancer research, lcsh:Diseases of the digestive system. Gastroenterology, Biomarkers, DNA Damage
وصف الملف: application/pdf
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المؤلفون: Edyta Heropolitanska Pliszka, Małgorzata Pac, Mateusz Maciejczyk, Bożena Mikołuć, Barbara Pietrucha, Halina Car, Radosław Motkowski
المصدر: Redox Biology, Vol 11, Iss, Pp 375-383 (2017)
Redox Biologyمصطلحات موضوعية: Prx 3, mitochondrial peroxiredoxin 3, DNA Repair, LCLs, lymphoblastoid cell lines, Fe, iron, Review Article, Biochemistry, Antioxidants, Nijmegen breakage syndrome (NBS), Glx, glyoxal, Bloom syndrome, mtETC, mitochondrial electron transport chain, lcsh:QH301-705.5, Cu, copper, 8-OHdG, 8-hydroxy-2-deoxyguanosine, ox-LDL, oxidised low-density lipoprotein, food and beverages, DS, Down Syndrome, UA, uric acid, Lipoproteins, LDL, CS, Cockayne Syndrome, Poly(ADP-ribose) Polymerases, lcsh:Medicine (General), Bloom Syndrome, GSH-Px, glutathione peroxidase, G6PD, glucose-6 phosphate dehydrogenase, DNA damage, TOP1mt, mitochondrial topoisomerase I, FA, Fanconi anaemia, mTOR, mammalian target of rapamycin, XP, Xeroderma pigmentosum, DDR, DNA damage response, 03 medical and health sciences, Oxidative damage, Humans, HO, heme oxygenase, BS, Bloom syndrome, NOX4, NADPH oxidase 4, Nijmegen Breakage Syndrome, Ataxia-telangiectasia (A-T), DNA-PKcs, DNA-dependent protein kinase catalytic subunit, MDA, malondialdehyde, XO, xanthine oxidase, GSSG, oxidised glutathione, medicine.disease, LWMA, low molecular weight antioxidants, 030104 developmental biology, DSBs, double strand breaks, Ataxia-telangiectasia, AA, ascorbic acid, GSSG-R, glutathione reductase, CAT, catalase, HR, homologous recombination, PARP, Poly (ADP-ribose) polymerases, Reactive Oxygen Species, Nijmegen breakage syndrome, 0301 basic medicine, MGlx, methylglyoxal, GSH, reduced glutathione, PDTC, ammonium pyrrolidinedithiocarbamate, Clinical Biochemistry, Mitochondrion, medicine.disease_cause, ALA, α-lipolic acid, HGS, Hutchinson-Gilford syndrome, LOX, lipoxygenase, t-butyl-OOH, tert-Butyl-hydroperoxide, CBS, chromosomal breakage syndromes, NAC, N-acetyl-L-cysteine, lcsh:R5-920, NADPH oxidase, GPx, glutathione peroxidase, biology, mROS, mitochondrial reactive oxygen species, Zn, zinc, Mitochondria, AOA3, ataxia with oculomotor apraxia type 3, PKC-δ, protein kinase C, X/XO, xanthine/xanthine oxidase, NADPH Oxidase 4, Signal Transduction, Premature aging, Bloom syndrome (BS), AOS, antioxidant defense systems, NAD+, oxidised nicotinamide adenine dinucleotide, Se, selenium, Ataxia Telangiectasia, ROS, reactive oxygen species, SOD, superoxide dismutase, GST, glutathione-S-transferase, medicine, Q10, ubiquinone, IR, ionising radiation, Organic Chemistry, A-T, Ataxia-telangiectasia, mtDNA, mitochondrial DNA, POLG, polymerase gamma, Oxidative Stress, NBS, Nijmegen breakage syndrome, Gene Expression Regulation, lcsh:Biology (General), ATM, Ataxia Telangiectasia Mutated gene, NOX2, NADPH oxidase 2, biology.protein, Cancer research, WS, Werner syndrome (WS), SMG-1, suppressor with morphological effect on genitalia family member, ATR, ATM and Rad3-related, Oxidative stress, DNA Damage
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3Academic Journal
المؤلفون: Mordes, Daniel, Ball, Heather L., Ehrhardt, Mark, Cortez, David
المساهمون: VANDERBILT UNIV MEDICAL CENTER NASHVILLE TN
المصدر: DTIC
مصطلحات موضوعية: Genetic Engineering and Molecular Biology, Medicine and Medical Research, BREAST CANCER, GENOME, DEOXYRIBONUCLEIC ACIDS, MUTATIONS, MOLECULAR PROPERTIES, LESIONS, PHOSPHORUS TRANSFERASES, PROTEINS, DAMAGE, YEASTS, ATR(ATM AND RAD3-RELATED), ATRIP(ATR-INTERACTING PROTEIN)
وصف الملف: text/html
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4Academic Journal
المؤلفون: Ball, Heather L., Ehrhardt, Mark, Mordes, Daniel, Cortez, David
المساهمون: VANDERBILT UNIV MEDICAL CENTER NASHVILLE TN
المصدر: DTIC
مصطلحات موضوعية: Genetic Engineering and Molecular Biology, Medicine and Medical Research, BREAST CANCER, GENOME, DAMAGE, PROTEINS, DEOXYRIBONUCLEIC ACIDS, MUTATIONS, YEASTS, MOLECULAR PROPERTIES, PHOSPHORUS TRANSFERASES, ATM(ATAXIA TELANGIECTASIA MUTATED), ATRIP(ATR INTERACTING PROTEIN), RPA(REPLICATION PROTEIN A), CRD(CHECKPOINT RECRUITMENT DOMAIN), ATR(ATM AND RAD3-RELATED)
وصف الملف: text/html
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5Electronic Resource
المؤلفون: VANDERBILT UNIV MEDICAL CENTER NASHVILLE TN, Mordes, Daniel, Ball, Heather L., Ehrhardt, Mark, Cortez, David
المصدر: DTIC
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6Electronic Resource
المؤلفون: VANDERBILT UNIV MEDICAL CENTER NASHVILLE TN, Ball, Heather L., Ehrhardt, Mark, Mordes, Daniel, Cortez, David
المصدر: DTIC
مصطلحات الفهرس: Genetic Engineering and Molecular Biology, Medicine and Medical Research, BREAST CANCER, GENOME, DAMAGE, PROTEINS, DEOXYRIBONUCLEIC ACIDS, MUTATIONS, YEASTS, MOLECULAR PROPERTIES, PHOSPHORUS TRANSFERASES, ATM(ATAXIA TELANGIECTASIA MUTATED), ATRIP(ATR INTERACTING PROTEIN), RPA(REPLICATION PROTEIN A), CRD(CHECKPOINT RECRUITMENT DOMAIN), ATR(ATM AND RAD3-RELATED), Text