المؤلفون: Folkert Kuipers, Leonie C. van Vark-van der Zee, Eric J.G. Sijbrands, Tim Vanmierlo, Kris Rutten, Vincent W. Bloks, Dieter Luetjohann, Harry W.M. Steinbusch, Monique T. Mulder, Anja Kerksiek, Silvia Friedrichs

المساهمون: Center for Liver, Digestive and Metabolic Diseases (CLDM), Psychiatrie & Neuropsychologie, RS: MHeNs School for Mental Health and Neuroscience, Internal Medicine

المصدر: Journal of alzheimers disease, 19(1), 117-127. IOS Press
Journal of Alzheimer's Disease, 19(1), 117-127. IOS Press
Journal of Alzheimers Disease, 19(1), 117-127. IOS Press BV

مصطلحات موضوعية: GAMMA-SECRETASE, Hippocampus, A-BETA GENERATION, seladin, ACTIVATION, Amyloid beta-Protein Precursor, Mice, chemistry.chemical_compound, 0302 clinical medicine, Desmosterol, Amyloid precursor protein, NEURONS, APPSLxPS1mut, brain cholesterol metabolism, TRANSGENIC MICE, 0303 health sciences, biology, General Neuroscience, Age Factors, Brain, General Medicine, Alzheimer's disease, AMYLOID PRECURSOR PROTEIN, Psychiatry and Mental health, Clinical Psychology, Cholesterol, 24S-HYDROXYCHOLESTEROL, oxysterols, LXR, lipids (amino acids, peptides, and proteins), Oxidoreductases Acting on CH-CH Group Donors, medicine.medical_specialty, Mice, Transgenic, Nerve Tissue Proteins, Presenilin, Mice, Neurologic Mutants, 03 medical and health sciences, CEREBROSPINAL-FLUID, Alzheimer Disease, Internal medicine, Presenilin-1, medicine, Animals, Liver X receptor, 030304 developmental biology, medicine.disease, GENE, Mice, Inbred C57BL, Disease Models, Animal, Endocrinology, chemistry, ABCA1, biology.protein, Geriatrics and Gerontology, LIVER-X-RECEPTOR, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc9a4d8aaf1710f320cb834d537efa3
https://doi.org/10.3233/jad-2010-1209

المؤلفون: Vanmierlo, Tim, Bloks, Vincent W., van Vark-van der Zee, Leonie C., Rutten, Kris, Kerksiek, Anja, Friedrichs, Silvia, Sijbrands, Eric J. G., Steinbusch, Harry W., Kuipers, Folkert, Luetjohann, Dieter, Mulder, Monique

المصدر: Vanmierlo , T , Bloks , V W , van Vark-van der Zee , L C , Rutten , K , Kerksiek , A , Friedrichs , S , Sijbrands , E J G , Steinbusch , H W , Kuipers , F , Luetjohann , D & Mulder , M 2010 , ' Alterations in Brain Cholesterol Metabolism in the APPSLxPS1mut mouse, a Model for Alzheimer's Disease ' , Journal of Alzheimer's Disease , vol. 19 , no. 1 , pp. 117-127 . https://doi.org/10.3233/JAD-2010-1209

مصطلحات موضوعية: APPSLxPS1mut, Alzheimer's disease, brain cholesterol metabolism, LXR, oxysterols, seladin

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/1f9beaf3-f7f1-4868-8ee4-61b70795ceb5
https://doi.org/10.3233/JAD-2010-1209