المؤلفون: Genaro, K, Doan, B, Johnstone, T, Gee, Kelvin, Yoshimura, Ryan, Hogenkamp, Derk

مصطلحات موضوعية: Morphine-antinociceptive tolerance, Opioid, Opioid withdrawal symptoms, Positive allosteric modulators, δ-subunit GABA(A) receptor, Analgesics, Analgesics, Opioid, Animals, Dose-Response Relationship, Drug, Female, Humans, Male, Mice, Mice, Knockout, Morphine, Receptors, GABA-A, Receptors, Opioid, delta, Water, gamma-Aminobutyric Acid

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9hp497vm

المؤلفون: Yaswanth Kuthati, Vaikar Navakanth Rao, Wei-Hsiu Huang, Prabhakar Busa, Chih-Shung Wong

المصدر: Antioxidants; Volume 12; Issue 7; Pages: 1478

مصطلحات موضوعية: diabetic neuropathic pain, dipeptidyl peptidase-4 inhibitor, teneligliptin, microglia, morphine antinociceptive tolerance

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Health Outcomes of Antioxidants and Oxidative Stress; https://dx.doi.org/10.3390/antiox12071478

الاتاحة: https://doi.org/10.3390/antiox12071478

المؤلفون: Zachary W. Reichenbach, Kelly DiMattio, Suren Rajakaruna, David Ambrose, William D. Cornwell, Ronald J. Tallarida, Thomas Rogers, Lee-Yuan Liu-Chen, Ronald F. Tuma, Sara Jane Ward

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: morphine, CB2 receptor agonist, antinociception, antinociceptive tolerance, inflammation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.803331/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/978a1c3db7cf456fbd08ebf0eadc29e8

المؤلفون: Reichenbach, Zachary, DiMattio, Kelly, Rajakaruna, Suren, Ambrose, David, Cornwell, William D., Tallarida, Ronald J., Rogers, Thomas, Liu-Chen, Lee-Yuan, Tuma, Ronald F., Ward, Sara Jane, Reichenbacher|0000-0003-4907-3502, Liu-Chen|0000-0001-5206-9497

المساهمون: Center for Substance Abuse Research (CSAR) (Temple University), Temple University. Hospital, Center for Inflammation, Translational, and Clinical Lung Research (Temple University)

مصطلحات موضوعية: Morphine, CB2 receptor agonist, Antinociception, Antinociceptive tolerance, Inflammation

وصف الملف: 11 pages

Relation: Frontiers Media; http://dx.doi.org/10.3389/fphar.2022.803331; Frontiers in Pharmacology, Vol. 13; Faculty/ Researcher Works; Reichenbach ZW, DiMattio K, Rajakaruna S, Ambrose D, Cornwell WD, Tallarida RJ, Rogers T, Liu-Chen L-, Tuma RF and Ward SJ (2022) Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966. Front. Pharmacol. 13:803331. doi:10.3389/fphar.2022.803331; http://hdl.handle.net/20.500.12613/9612

الاتاحة: https://hdl.handle.net/20.500.12613/9612

المؤلفون: Alok K. Paul, Krystel L. Woolley, Mohammed Rahmatullah, Polrat Wilairatana, Jason A. Smith, Nuri Gueven, Nikolas Dietis

المصدر: Pharmaceuticals; Volume 15; Issue 7; Pages: 789

مصطلحات موضوعية: UTA1003, UFP-505, morphine, antinociception, antinociceptive tolerance, motor behaviour, mixed opioid, mixed activity

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/ph15070789

الاتاحة: https://doi.org/10.3390/ph15070789

المؤلفون: Gabel, Florian, Hovhannisyan, Volodya, Andry, Virginie, Goumon, Yannick

المساهمون: Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Plateau technique de Spectrométrie de Masse (SM-INCI / CNRS UPR3212), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), ANR-17-EURE-0022,EURIDOL,Ecole Universitaire de Recherche Interdisciplinaire sur la Douleur(2017)

المصدر: ISSN: 0007-1188.

مصطلحات موضوعية: M3G, Morphine, UDP-glucuronosyltransferase, antinociception, antinociceptive tolerance, metabolism, sex differences, [SCCO.NEUR]Cognitive science/Neuroscience

Relation: info:eu-repo/semantics/altIdentifier/pmid/34986502; inserm-03542469; https://inserm.hal.science/inserm-03542469; https://inserm.hal.science/inserm-03542469/document; https://inserm.hal.science/inserm-03542469/file/Revised%20version%20-%20Gabel%20et%20al%235%20v1-combined.pdf; PUBMED: 34986502

الاتاحة: https://inserm.hal.science/inserm-03542469
https://inserm.hal.science/inserm-03542469/document
https://inserm.hal.science/inserm-03542469/file/Revised%20version%20-%20Gabel%20et%20al%235%20v1-combined.pdf
https://doi.org/10.1111/bph.15792

المؤلفون: Yu-zhe Zhang (11712167), Meng-meng Wang (2503936), Si-yu Wang (599072), Xiao-fang Wang (11712170), Wen-jiao Yang (11712173), Ya-nan Zhao (1569496), Feng-tong Han (11712176), Yao Zhang (134381), Ning Gu (226838), Chang-lin Wang (11712179)

مصطلحات موضوعية: Biochemistry, Genetics, Neuroscience, Pharmacology, Ecology, Cancer, Chemical Sciences not elsewhere classified, prolonged antinociceptive effects, present investigation established, peripherally induced significant, like side effects, fewer side effects, developing novel analgesics, conditioned place preference, analogue 6 decreased, acting antiallodynic effects, 6 administered centrally, analogue 5 exhibited, 6 exhibited reduced, chronic antinociceptive tolerance, analogues 5, reduced opioid, vector conjugation, supraspinal level, potent μ, potent pharmaceuticals, peripheral level, multiple modifications, motor impairment, gastrointestinal transit

Relation: https://figshare.com/articles/journal_contribution/Novel_Cyclic_Endomorphin_Analogues_with_Multiple_Modifications_and_Oligoarginine_Vector_Exhibit_Potent_Antinociception_with_Reduced_Opioid-like_Side_Effects/17021882

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01631.s001

المؤلفون: Yaswanth Kuthati, Prabhakar Busa, Srikrishna Tummala, Vaikar Navakanth Rao, Venkata Naga Goutham Davuluri, Yen-Peng Ho, Chih-Shung Wong

المصدر: Antioxidants; Volume 10; Issue 2; Pages: 195

مصطلحات موضوعية: morphine antinociceptive tolerance, MPDA, neuropathic pain, morphine, reactive oxygen species, oxidative stress

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/antiox10020195

الاتاحة: https://doi.org/10.3390/antiox10020195

المؤلفون: Lilius, T., Kangas, E., Niemi, M., Rauhala, P., Kalso, E.

المساهمون: HUSLAB, Medicum, Department of Clinical Pharmacology, Department of Pharmacology, Faculty of Medicine, University of Helsinki, Clinicum, Pekka Rauhala / Principal Investigator, Eija Kalso / Principal Investigator, Department of Diagnostics and Therapeutics, Anestesiologian yksikkö, HUS Perioperative, Intensive Care and Pain Medicine

مصطلحات موضوعية: anaesthetics, dissociative, analgesics, opioid, ketamine, morphine, oxycodone, pain, tolerance, NMDA RECEPTOR ANTAGONIST, ANTINOCICEPTIVE TOLERANCE, HEALTHY-VOLUNTEERS, PERSISTENT PAIN, RODENT MODELS, INHIBITION, RAT, GLUCURONIDATION, DEPENDENCE, PHARMACOKINETICS, Surgery, anesthesiology, intensive care, radiology

وصف الملف: application/pdf

Relation: Finnish Medical Society (Finska Lakaresallskapet); University of Helsinki 375 Jubilee Funds; Emil Aaltonen Foundation; Sohlberg Foundation; The Maud Kuistila Memorial Foundation; Finnish Association for the Study of Pain; European Union Seventh Framework Programme (602919).; Lilius , T , Kangas , E , Niemi , M , Rauhala , P & Kalso , E 2018 , ' Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine : from behaviour to drug availability ' , British Journal of Anaesthesia , vol. 120 , no. 4 , pp. 818-826 . https://doi.org/10.1016/j.bja.2017.11.081; ORCID: /0000-0003-2036-3522/work/54789750; http://hdl.handle.net/10138/299449; edcab802-6ddf-4c8b-93f1-c66dda536d03; 85045944808; 000438193500024

الاتاحة: http://hdl.handle.net/10138/299449

المؤلفون: Jokinen, Viljami, Sidorova, Yulia, Viisanen, Hanna, Suleymanova, Ilida, Tiilikainen, Henna, Li, Zhilin, Lilius, Tuomas O., Matlik, Kert, Anttila, Jenni E., Airavaara, Mikko, Tian, Li, Rauhala, Pekka V., Kalso, Eija A.

المساهمون: Medicum, Department of Pharmacology, Institute of Biotechnology, Research Programs Unit, Neuroscience Center, Pekka Rauhala / Principal Investigator, Eija Kalso / Principal Investigator, Clinicum, Anestesiologian yksikkö, Department of Diagnostics and Therapeutics, HUS Perioperative, Intensive Care and Pain Medicine

مصطلحات موضوعية: flow cytometry, opioid, neuroinflammation, nociception, microglia, transcriptomics, CENTRAL-NERVOUS-SYSTEM, GENE-RELATED PEPTIDE, NEUROPATHIC PAIN, ANTINOCICEPTIVE TOLERANCE, OPIOID ANALGESIA, CELL ACTIVATION, PARKINSONS-DISEASE, PROTEIN-ALPHA, CORD-INJURY, Neurosciences, Neurology and psychiatry

وصف الملف: application/pdf

Relation: Biomedicum Functional Genomics Unit (FuGU) and Dr. Catherine Icay are acknowledged for their technical work and providing the original method protocols. Institute of Biotechnology, University of Helsinki is acknowledged (http://www.biocenter.helsinki.fi/bi/histoscanner/index.html). The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no 602919, Finnish MedicalSociety (Finska Lakaresallskapet), University of Helsinki 375th Anniversary Grant, University of Helsinki, and Centre for International Mobility of Finland CIMO.; Jokinen , V , Sidorova , Y , Viisanen , H , Suleymanova , I , Tiilikainen , H , Li , Z , Lilius , T O , Matlik , K , Anttila , J E , Airavaara , M , Tian , L , Rauhala , P V & Kalso , E A 2018 , ' Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance ' , Neuroscience , vol. 375 , pp. 10-24 . https://doi.org/10.1016/j.neuroscience.2018.01.048; ORCID: /0000-0003-0222-7076/work/43467521; ORCID: /0000-0003-2036-3522/work/43467666; ORCID: /0000-0002-2026-1609/work/43467709; ORCID: /0000-0003-2867-2848/work/43467519; http://hdl.handle.net/10138/300672; 08bd4a31-bd8c-412c-9bff-b2b1f88eb878; 85042356278; 000426996600002

الاتاحة: http://hdl.handle.net/10138/300672

المؤلفون: Yan-Fen Zhao, Feng Zhao, Peng-Sen Liu, Ke Mao

المصدر: Medical Journal of Chinese People's Liberation Army, Vol 45, Iss 12, Pp 1242-1247 (2020)

مصطلحات موضوعية: lcsh:R5-920, animal structures, fungi, lcsh:R, lcsh:Medicine, hsp60, morphine antinociceptive tolerance, lcsh:Medicine (General), trl4-p38mapk

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doajarticles::953c0d908ae8879364d7c6aee91ecec0
http://plamj.org/index.php/plamj/article/view/2347

المؤلفون: Florian Gabel, Volodya Hovhannisyan, Virginie Andry, Yannick Goumon

المساهمون: Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Plateau technique de Spectrométrie de Masse (SM-INCI / CNRS UPR3212), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Goumon, Yannick

المصدر: British Journal of Pharmacology
British Journal of Pharmacology, 2022, Online ahead of print. ⟨10.1111/bph.15792⟩

مصطلحات موضوعية: Pharmacology, sex differences, Morphine, [SCCO.NEUR]Cognitive science/Neuroscience, [SCCO.NEUR] Cognitive science/Neuroscience, M3G, metabolism, UDP-glucuronosyltransferase, antinociception, antinociceptive tolerance

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0653db9bf7fb2c6ad2ecf9a5a7096520
https://www.hal.inserm.fr/inserm-03542469

المؤلفون: Zanza C., Longhitano Y., Lin E., Luo J., Artico M., Savarese B., Bonato V., Piccioni A., Franceschi F., Taurone S., Abenavoli L., Berger J. M.

المساهمون: Zanza, C., Longhitano, Y., Lin, E., Luo, J., Artico, M., Savarese, B., Bonato, V., Piccioni, A., Franceschi, F., Taurone, S., Abenavoli, L., Berger, J. M.

مصطلحات موضوعية: ketorolac, lidocaine, magnesium, multimodal analgesia, opioid antinociceptive tolerance, opioid sensitivity, opioid-induced hyperalgesia, opioid-sparing, severe postoperative pain

Relation: info:eu-repo/semantics/altIdentifier/pmid/33267764; info:eu-repo/semantics/altIdentifier/wos/WOS:000752563700001; volume:16; issue:3; firstpage:288; lastpage:293; numberofpages:6; journal:REVIEWS ON RECENT CLINICAL TRIALS; http://hdl.handle.net/11573/1576731; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85114055824

الاتاحة: http://hdl.handle.net/11573/1576731
https://doi.org/10.2174/1574887115666201202105620

المؤلفون: Gabel, Florian

المساهمون: STAR, ABES

مصطلحات موضوعية: [SDV.SA] Life Sciences [q-bio]/Agricultural sciences, Metabolism, Dimorphisme sexuel, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Morphine, Métabolisme, Tolérance antinociceptive, Sex differences, Antinociceptive tolerance, Analgesia, Analgésie

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______166::e01a79e67808480af01d7422775027a5
https://theses.hal.science/tel-03618421

المؤلفون: Edwin Lin, Valeria Bonato, Samanta Taurone, Jerry Luo, Benedetta Savarese, Andrea Piccioni, Francesco Franceschi, Christian Zanza, Marco Artico, Jack M. Berger, Yaroslava Longhitano, Ludovico Abenavoli

مصطلحات موضوعية: Lidocaine, Analgesic, ketorolac, lidocaine, magnesium, multimodal analgesia, opioid antinociceptive tolerance, opioid sensitivity, opioid-induced hyperalgesia, opioid-sparing, severe postoperative pain, Pacu, Double-Blind Method, medicine, Humans, Magnesium, Opioid-induced hyperalgesia, Retrospective Studies, Pharmacology, Pain, Postoperative, biology, business.industry, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, biology.organism_classification, Ketorolac, Analgesics, Opioid, Nociception, Opioid, Anesthesia, Hyperalgesia, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918cc4109292fb3f2eb84cb4e5384b6d
http://hdl.handle.net/11573/1576731

المؤلفون: Hanna Viisanen, Viljami Jokinen, Tuomas Lilius, Pekka Rauhala, Li Tian, Yulia Sidorova, Kert Mätlik, Jenni E. Anttila, Henna Tiilikainen, Ilida Suleymanova, Mikko Airavaara, Zhilin Li, Eija Kalso

المساهمون: Medicum, Department of Pharmacology, Institute of Biotechnology, Research Programs Unit, Neuroscience Center, Pekka Rauhala / Principal Investigator, Eija Kalso / Principal Investigator, Clinicum, Anestesiologian yksikkö, Department of Diagnostics and Therapeutics, HUS Perioperative, Intensive Care and Pain Medicine

المصدر: Neuroscience. 375:10-24

مصطلحات موضوعية: Male, 0301 basic medicine, ANTINOCICEPTIVE TOLERANCE, microglia, 3124 Neurology and psychiatry, Nociceptive Pain, neuroinflammation, Rats, Sprague-Dawley, transcriptomics, 0302 clinical medicine, PARKINSONS-DISEASE, nociception, Morphine, Microglia, General Neuroscience, NEUROPATHIC PAIN, Brain, Drug Tolerance, 3. Good health, Analgesics, Opioid, medicine.anatomical_structure, Nociception, Spinal Cord, Hyperalgesia, Models, Animal, PROTEIN-ALPHA, medicine.symptom, Cell activation, Neuroglia, medicine.drug, medicine.medical_specialty, Central nervous system, Biology, 03 medical and health sciences, Internal medicine, medicine, Animals, OPIOID ANALGESIA, CELL ACTIVATION, Neuroinflammation, flow cytometry, CENTRAL-NERVOUS-SYSTEM, 3112 Neurosciences, Spinal cord, GENE-RELATED PEPTIDE, 030104 developmental biology, Endocrinology, CORD-INJURY, nervous system, Opioid, opioid, Transcriptome, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e4be327249bd5a5168adf6082f0623
https://doi.org/10.1016/j.neuroscience.2018.01.048

المؤلفون: Gabel, Florian

المساهمون: Strasbourg, Goumon, Yannick

مصطلحات موضوعية: Métabolisme, Dimorphisme sexuel, Analgésie, Morphine, Tolérance antinociceptive, Metabolism, Sex differences, Analgesia, Antinociceptive tolerance, 612.8, 615.7

Relation: http://www.theses.fr/2021STRAJ073/document

الاتاحة: http://www.theses.fr/2021STRAJ073/document

المؤلفون: Gabel, Florian

المساهمون: Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg, Yannick Goumon

المصدر: https://theses.hal.science/tel-03618421 ; Sciences agricoles. Université de Strasbourg, 2021. Français. ⟨NNT : 2021STRAJ073⟩.

مصطلحات موضوعية: Metabolism, Sex differences, Analgesia, Morphine, Antinociceptive tolerance, Métabolisme, Dimorphisme sexuel, Analgésie, Tolérance antinociceptive, [SDV.SA]Life Sciences [q-bio]/Agricultural sciences, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

Relation: NNT: 2021STRAJ073; tel-03618421; https://theses.hal.science/tel-03618421; https://theses.hal.science/tel-03618421/document; https://theses.hal.science/tel-03618421/file/Gabel_Florian_2021_ED414.pdf

الاتاحة: https://theses.hal.science/tel-03618421
https://theses.hal.science/tel-03618421/document
https://theses.hal.science/tel-03618421/file/Gabel_Florian_2021_ED414.pdf

المؤلفون: Doyle T. M., Janes K., Chen Z., Grace P. M., Esposito E., Cuzzocrea S., Largent-Milnes T. M., Neumann W. L., Watkins L. R., Spiegel S., Vanderah T. W., Salvemini D.

المساهمون: Doyle, T. M., Janes, K., Chen, Z., Grace, P. M., Esposito, E., Cuzzocrea, S., Largent-Milnes, T. M., Neumann, W. L., Watkins, L. R., Spiegel, S., Vanderah, T. W., Salvemini, D.

مصطلحات موضوعية: Sphingosine-1-phosphate receptor 1, Opioid-induced hyperalgesia, Antinociceptive tolerance, Neuroinflammation, Interleukin-1beta

Relation: info:eu-repo/semantics/altIdentifier/pmid/32301840; info:eu-repo/semantics/altIdentifier/wos/WOS:000571186100017; volume:161; issue:9; firstpage:2107; lastpage:2118; numberofpages:12; journal:PAIN; http://hdl.handle.net/11570/3192442; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85091931982

الاتاحة: http://hdl.handle.net/11570/3192442
https://doi.org/10.1097/j.pain.0000000000001888

المؤلفون: Fei GAO, Shao-dong ZHENG, Yi-cong LI, Yu ZHAO

المصدر: Medical Journal of Chinese People's Liberation Army, Vol 42, Iss 12, Pp 1056-1060 (2017)

مصطلحات موضوعية: lcsh:R5-920, lcsh:R, spinal cord, lcsh:Medicine, morphine, curcumin, Toll-like receptor 4, lcsh:Medicine (General), antinociceptive tolerance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doajarticles::2ffe2b67396c92f4ac788f32ba906d03
http://www.plamj.org/index.php/plamj/article/view/1654