المؤلفون: Thomas Cochin, Sabine Noal, Dinu Stefan, Damien Bodet, Jérémie Rouger, Marine Dorbeau, Zoé Neviere

المصدر: Frontiers in Oncology, Vol 14 (2025)

مصطلحات موضوعية: inflammatory myofibroblastic tumor, crizotinib, sequential treatment ALK-TKI, pediatric, ALK inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1505257/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/4ed80405c0954a4f96e6d598a772c5be

المؤلفون: Xiaoli Mu, Yan Li

المصدر: Frontiers in Pharmacology, Vol 15 (2024)

مصطلحات موضوعية: large-cell neuroendocrine carcinoma, lorlatinib, multiple primary malignancies, ALK tyrosine kinase inhibitor (ALK-TKI), brain metastases, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1413897/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/85ad66f21b23474488dfdaa25480fc80

المؤلفون: Qiong He, Xinmin Yu, Junrong Yan, Xun Shi, Hongming Pan

المصدر: Heliyon, Vol 10, Iss 11, Pp e32030- (2024)

مصطلحات موضوعية: NSCLC, Histologic transformation, ALK-TKI, Resistance mechanism, Case report, Science (General), Q1-390, Social sciences (General), H1-99

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024080617; https://doaj.org/toc/2405-8440

URL الوصول: https://doaj.org/article/e04ca6bcd5b146f4a74a1bdef3846954

المؤلفون: Jin Xiong, Lei Xia

المصدر: Frontiers in Oncology, Vol 14 (2024)

مصطلحات موضوعية: pleural effusion NGS, combination therapy, long-term survival, multiple-line ALK-TKI, case report, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1419306/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/cb72cb448c2f4df9aea7e3b2d6dc5ca1

المؤلفون: Ou, Sai-Hong Ignatius, Nagasaka, Misako, Brazel, Danielle, Hou, Yujie, Zhu, Viola W

المصدر: Translational Oncology. 14(11)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Clinical Research, Cancer, Genetics, Lung Cancer, Lung, Clinical Trials and Supportive Activities, TPX-0131, NVL-655, "Single mutant active", "Double mutant active", ALK plus NSCLC, Anaplastic lymphoma kinase tyrosine kinase, inhibitors 4th-generation ALK TKI, 4th-generation ALK TKI, ALK+ NSCLC, Anaplastic lymphoma kinase tyrosine kinase inhibitors, “Double mutant active”, “Single mutant active”, Biochemistry and Cell Biology, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7rk5x7pc

المؤلفون: Lee ATM, Ou SI

المصدر: Lung Cancer: Targets and Therapy, Vol Volume 15, Pp 19-27 (2024)

مصطلحات موضوعية: eml4-alk variant 3a/b, tp53 mutation, alk tkis, fifth generation alk tki, alk+ nsclc, circulating tumor dna, next-generation sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.dovepress.com/overcoming-central--sheet-6-c6-alk-mutation-l1256f-tp53-mutations-and--peer-reviewed-fulltext-article-LCTT; https://doaj.org/toc/1179-2728

URL الوصول: https://doaj.org/article/2546c96c26c048d3bbe7c62697e7dedb

المؤلفون: Anita Gorzelak-Magiera, Małgorzata Domagała-Haduch, Jacek Kabut, Iwona Gisterek-Grocholska

المصدر: Biomedicines, Vol 12, Iss 10, p 2308 (2024)

مصطلحات موضوعية: ALK-TKI, lung cancer, ALK detection, targeted therapy, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/10/2308; https://doaj.org/toc/2227-9059

URL الوصول: https://doaj.org/article/8252cef8f2c74b5095f3f33a30be9040

المؤلفون: Chen Yang, Rui Zeng, Yawen Zha, Yani Li, Ting Wang, Ruolan Zhao, Minying Li, Jingjing Zhang

المصدر: Frontiers in Immunology, Vol 15 (2024)

مصطلحات موضوعية: ALK-positive, lung squamous cell carcinoma, clinical complete response, ALK-TKI, immunotherapy, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1360671/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/7eacfcd31c234eb0821b614340d8d19c

المؤلفون: Urbanska, Edyta M., Grauslund, Morten, Berger, Siv M.S., Costa, Junia C., Koffeldt, Peter R., Sørensen, Jens B., Santoni-Rugiu, Eric

المصدر: Urbanska , E M , Grauslund , M , Berger , S M S , Costa , J C , Koffeldt , P R , Sørensen , J B & Santoni-Rugiu , E 2024 , ' ALK-tyrosine kinase inhibitor intrinsic resistance due to de novo MET-amplification in metastatic ALK-rearranged non-small cell lung cancer effectively treated by alectinib-crizotinib combination-case report ' , Translational Lung Cancer Research , vol. 13 , no. 9 , pp. 2453-2462 . https://doi.org/10.21037/tlcr-24-439

مصطلحات موضوعية: ALK-rearranged non-small cell lung cancer (ALK-rearranged NSCLC), case report, De novo MET-amplification, intrinsic ALK-tyrosine kinase inhibitor resistance (intrinsic ALK-TKI resistance), tyrosine kinase inhibitor combination (TKI combination)

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/alktyrosine-kinase-inhibitor-intrinsic-resistance-due-to-de-novo-metamplification-in-metastatic-alkrearranged-nonsmall-cell-lung-cancer-effectively-treated-by-alectinibcrizotinib-combinationcase-report(b5ab96b5-b7d6-4efb-adf2-71014d99f49e).html
https://doi.org/10.21037/tlcr-24-439
https://curis.ku.dk/ws/files/410080999/90934_PB4_3184_R4.pdf

المؤلفون: Sánchez Herrero, Estela, Provencio Pulla, Mariano

المساهمون: UAM. Departamento de Medicina

مصطلحات موضوعية: ALK-TKI, EML4-ALK, extracellular vesicles, liquid biopsy, NSCLC, Medicina

وصف الملف: application/pdf

Relation: Clinical Chemistry; https://doi.org/10.1093/clinchem/hvac021; Comunidad de Madrid. PI17/01977; Gobierno de España. RTI2018-093569-B-I00; Comunidad de Madrid. S2017/BMD-3733-2; Gobierno de España. SAF2015-71231-REDT; Gobierno de España. RED2018-102411-T; info:eu-repo/grantAgreement/EC/H2020/875160; Clinical Chemistry 68.5 (2022): 668-679; 0009-9147 (print); 1530-8561 (online); http://hdl.handle.net/10486/711467; 668; 679; 68

الاتاحة: http://hdl.handle.net/10486/711467
https://doi.org/10.1093/clinchem/hvac021

المؤلفون: Lee ATM, Ou SI

المصدر: Lung Cancer: Targets and Therapy, Vol Volume 15, Pp 19-27 (2024)

مصطلحات موضوعية: eml4-alk variant 3a/b, tp53 mutation, alk tkis, fifth generation alk tki, alk+ nsclc, circulating tumor dna, next-generation sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.dovepress.com/overcoming-central--sheet-6-c6-alk-mutation-l1256f-tp53-mutations-and--peer-reviewed-fulltext-article-LCTT; https://doaj.org/toc/1179-2728; https://doaj.org/article/2546c96c26c048d3bbe7c62697e7dedb

الاتاحة: https://doaj.org/article/2546c96c26c048d3bbe7c62697e7dedb

المؤلفون: DING Ning, ZHOU Jiebai

المصدر: 陆军军医大学学报, Vol 44, Iss 24, Pp 2493-2499 (2022)

مصطلحات موضوعية: alk-tki-resistance mechanism, compound mutations, drug resistance, rebiopsy, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://aammt.tmmu.edu.cn/Upload/rhtml/202209192.htm; https://doaj.org/toc/2097-0927

URL الوصول: https://doaj.org/article/dfb85b4566c24718bd1f46e64f621960

المؤلفون: Qin Chen, Jingjing Zhang, Xuan Wang, Wenkang Zong, Leina Sun, Jianwen Qin, Yan Yin

المصدر: Frontiers in Oncology, Vol 13 (2023)

مصطلحات موضوعية: large cell neuroendocrine carcinoma, EML4-ALK rearrangement, ALK-TKI inhibitor, alectinib, immunohistochemistry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1227980/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/144b64a9358f4818a983073cf4c0a5b2

المؤلفون: Ruiying Zhao, Lianying Guo, Bo Zhang, Jikai Zhao, Chan Xiang, Shengnan Chen, Jinchen Shao, Lei Zhu, Min Ye, Yuchen Han

المصدر: The Journal of Pathology: Clinical Research, Vol 8, Iss 6, Pp 538-549 (2022)

مصطلحات موضوعية: ALK, NGS, Ventana IHC, NSCLC, ALK‐TKI, Pathology, RB1-214

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2056-4538

URL الوصول: https://doaj.org/article/3f651fa0561242a1aec8f72af8ba66c9

المؤلفون: Ahn, Myung J., Kim, Hye R., Yang, James C. H., Han, Ji-Yu, Li, Jacky Yu-Chung, Hochmair, Maximilian J., Chang, Gee-Chen, Delmonte, Angelo, Lee, Ki H., Campelo, Rosario G., Gridelli, Cesare, Spira, Alexander, I, Califano, Raffaele, Griesinger, Frank, Ghosh, Sharmistha, Felip, Enriqueta, Kim, Dong-Wan, Liu, Yuyin, Zhang, Pingkuan, Popat, Sanjay, Camidge, D. Ross

المساهمون: Kim, Dong-Wan

مصطلحات موضوعية: EML4-ALK FUSION GENE, OPEN-LABEL, CHEMOTHERAPY, ALECTINIB, EGFR, ALK TKI-naive, Anaplastic lymphoma kinase, Clinical trial, First line, Tyrosine kinase inhibitor

Relation: Clinical Lung Cancer, Vol.23 No.8, pp.720-730; https://hdl.handle.net/10371/189405; 000905581000019; 2-s2.0-85136735466; 177273

الاتاحة: https://hdl.handle.net/10371/189405
https://doi.org/10.1016/j.cllc.2022.07.008

المؤلفون: Estela Sánchez‐Herrero, Roberto Serna‐Blasco, Vadym Ivanchuk, Rosario García‐Campelo, Manuel Dómine Gómez, José M. Sánchez, Bartomeu Massutí, Noemi Reguart, Carlos Camps, Sandra Sanz‐Moreno, Silvia Calabuig‐Fariñas, Eloísa Jantus‐Lewintre, Magdalena Arnal, Dietmar Fernández‐Orth, Virginia Calvo, Víctor González‐Rumayor, Mariano Provencio, Atocha Romero

المصدر: Molecular Oncology, Vol 15, Iss 9, Pp 2363-2376 (2021)

مصطلحات موضوعية: ALK‐TKI, EML4‐ALK, liquid biopsy, NGS, NSCLC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

URL الوصول: https://doaj.org/article/f8857d8e937348c0ac60929a958c48fe

المؤلفون: Xia Luo, Zhen Zhou, Xiaohui Zeng, Liubao Peng, Qiao Liu

المصدر: Frontiers in Public Health, Vol 10 (2022)

مصطلحات موضوعية: cost-effectiveness, Non-small cell lung cancer, ALK-TKI, ensartinib, domestic anticancer drug, China, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpubh.2022.985834/full; https://doaj.org/toc/2296-2565

URL الوصول: https://doaj.org/article/9e7d3d0c7eea4fe2964b3e08eeac9e17

المؤلفون: Ari Raphael, Amir Onn, Liran Holtzman, Julia Dudnik, Damien Urban, Waleed Kian, Aharon Y. Cohen, Mor Moskovitz, Alona Zer, Jair Bar, Natalie Maimon Rabinovich, Shirly Grynberg, Cecilie Oedegaard, Abed Agbarya, Nir Peled, Tzippy Shochat, Elizabeth Dudnik

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: comprehensive genomic profiling, next-generation sequencing, ALK, failure of ALK TKI, acquired resistance, decision impact, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.874712/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/f85c5c5f27684af1b3b0753d584f245f

المؤلفون: Yuan Wang, Jing He, Manyu Xu, Qingfeng Xue, Cindy Zhu, Juan Liu, Yaping Zhang, Wenyu Shi

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: ALCL, ALK, ALK-TKI, lymphoma, drug resistance, therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.815654/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/10b4a87fa2bd47a5a57d14ca338b0d13

المؤلفون: Minari R., Valentini S., Madeddu D., Cavazzoni A., La Monica S., Lagrasta C. A. M., Bertorelli R., De Sanctis V., Fassan P., Azzoni C., Bottarelli L., Frati C., Gnetti L., Facchinetti F., Petronini P. G., Alfieri R., Romanel A., Tiseo M.

المساهمون: Minari, R., Valentini, S., Madeddu, D., Cavazzoni, A., La Monica, S., Lagrasta, C. A. M., Bertorelli, R., De Sanctis, V., Fassan, P., Azzoni, C., Bottarelli, L., Frati, C., Gnetti, L., Facchinetti, F., Petronini, P. G., Alfieri, R., Romanel, A., Tiseo, M.

مصطلحات موضوعية: ALK TKI, MYC amplification, NSCLC, Resistance mechanism, YES1 amplification

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/35199053; volume:3; issue:2; firstpage:1002781; lastpage:1002788; numberofpages:8; journal:JTO CLINICAL AND RESEARCH REPORTS; http://hdl.handle.net/11572/338238; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85124278389; https://www.jtocrr.org/article/S2666-3643(22)00003-0/fulltext

الاتاحة: http://hdl.handle.net/11572/338238
https://doi.org/10.1016/j.jtocrr.2022.100278
https://www.jtocrr.org/article/S2666-3643(22)00003-0/fulltext