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    المصدر: GMS Hygiene and Infection Control; VOL: 17; DOC23 /20221206/

    Relation: Fundação Sistema Estadual de Análise de Dados (SEADE), 2021. Available from: https://www.seade.gov.br/coronavirus/#; Burton MJ, Clarkson JE, Goulao B, Glenny AM, McBain AJ, Schilder AG, Webster KE, Worthington HV. Antimicrobial mouthwashes (gargling) and nasal sprays administered to patients with suspected or confirmed COVID-19 infection to improve patient outcomes and to protect healthcare workers treating them. Cochrane Database Syst Rev. 2020 Sep;9:CD013627. DOI:10.1002/14651858.CD013627.pub2; Carrouel F, Conte MP, Fisher J, Gonçalves LS, Dussart C, Llodra JC, Bourgeois D. COVID-19: A Recommendation to Examine the Effect of Mouthrinses with beta-Cyclodextrin Combined with Citrox in Preventing Infection and Progression. J Clin Med. 2020 Apr;9(4). DOI:10.3390/jcm9041126; Carrouel F, Gonçalves LS, Conte MP, Campus G, Fisher J, Fraticelli L, Gadea-Deschamps E, Ottolenghi L, Bourgeois D. Antiviral Activity of Reagents in Mouth Rinses against SARS-CoV-2. J Dent Res. 2021 Feb;100(2):124-32. DOI:10.1177/0022034520967933; Carrouel F, Valette M, Gadea E, Esparcieux A, Illes G, Langlois ME, Perrier H, Dussart C, Tramini P, Ribaud M, Bouscambert-Duchamp M, Bourgeois D. Use of an antiviral mouthwash as a barrier measure in the SARS-CoV-2 transmission in adults with asymptomatic to mild COVID-19: a multicentre, randomized, double-blind controlled trial. Clin Microbiol Infect. 2021 Oct;27(10):1494-501. DOI:10.1016/j.cmi.2021.05.028; Casale M, Rinaldi V, Sabatino L, Moffa A, Ciccozzi M. Could nasal irrigation and oral rinse reduce the risk for COVID-19 infection? Int J Immunopathol Pharmacol. 2020 Jan-Dec;34. DOI:10.1177/2058738420941757; Chaudhary P, Melkonyan A, Meethil A, Saraswat S, Hall DL, Cottle J, Wenzel M, Ayouty N, Bense S, Casanova F, Chaney M, Chase H, Hermel R, McClement M, Sesson C, Woolsey B, Kumar P. Estimating salivary carriage of severe acute respiratory syndrome coronavirus 2 in nonsymptomatic people and efficacy of mouthrinse in reducing viral load: A randomized controlled trial. J Am Dent Assoc. 2021 Nov;152(11):903-8. DOI:10.1016/j.adaj.2021.05.021; Choudhury IM, Shabnam N, Ahsan T, Kabir MS, Khan R, Ahsan SA. Effect of 1?% povidone iodine mouthwash/gargle, nasal and eye drop in COVID -19 patient. Biores Comm. 2021;7(1): 919-23. DOI:10.3329/brc.v7i1.54245; da Fonseca Orcina B, Vilhena FV, Cardoso de Oliveira R, Marques da Costa Alves L, Araki K, Toma SH, Ragghianti Zangrando MS, da Silva Santos PS. A Phthalocyanine Derivate Mouthwash to Gargling/Rinsing as an Option to Reduce Clinical Symptoms of COVID-19: Case Series. Clin Cosmet Investig Dent. 2021;13:47-50. DOI:10.2147/CCIDE.S295423; da Silva Santos PS, da Fonseca Orcina B, da Costa Alves LM, et al. A recommendation of PHTALOX® mouthwash for preventing infection and progression of COVID-19. Acta Scient Dent Sci. 2020;4(12):111-2. DOI:10.31080/ASDS.2020.04.0991; da Silva Santos PS, da Fonseca Orcina B, Machado RRG, Vilhena FV, da Costa Alves LM, Zangrando MSR, de Oliveira RC, Soares MQS, Simão ANC, Pietro ECIN, Kuroda JPG, de Almeida Benjamim IA, Araujo DB, Toma SH, Flor L, Araki K, Durigon EL. Beneficial effects of a mouthwash containing an antiviral phthalocyanine derivative on the length of hospital stay for COVID-19: randomised trial. Sci Rep. 2021 Oct 7;11(1):19937. DOI:10.1038/s41598-021-99013-5; de Almeida GB, Pronunciate M, Grotto RMT, Azevedo Pugliesi E, Guimarães RB, Vilches TN, Mendes Coutinho R, Catão RC, Ferreira CP, Fortaleza CMCB. Two hundred days of COVID-19 in São Paulo State, Brazil. Epidemiol Infect. 2020 Dec;148:e295. DOI:10.1017/S0950268820002927; Eduardo FP, Corrêa L, Heller D, Daep CA, Benitez C, Malheiros Z, Stewart B, Ryan M, Machado CM, Hamerschlak N, Rebello Pinho JR, Bezinelli LM. Salivary SARS-CoV-2 load reduction with mouthwash use: A randomized pilot clinical trial. Heliyon. 2021 Jun;7(6):e07346. DOI:10.1016/j.heliyon.2021.e07346; Encinar JA, Menendez JA. Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2'-O-Methylation of Viral RNA. Viruses. 2020 05;12(5). DOI:10.3390/v12050525; Fernandes Matuck B, Dolhnikoff M, Maia GVA, Isaac Sendyk D, Zarpellon A, Costa Gomes S, Duarte-Neto AN, Rebello Pinho JR, Gomes-Gouvêa MS, Sousa SCOM, Mauad T, Saldiva PHDN, Braz-Silva PH, da Silva LFF. Periodontal tissues are targets for Sars-Cov-2: a post-mortem study. J Oral Microbiol. 2020 Nov;13(1):1848135. DOI:10.1080/20002297.2020.1848135; Fortaleza CMCB, Guimarães RB, Catão RC, Ferreira CP, Berg de Almeida G, Nogueira Vilches T, Pugliesi E. The use of health geography modeling to understand early dispersion of COVID-19 in São Paulo, Brazil. PLoS One. 2021;16(1):e0245051. DOI:10.1371/journal.pone.0245051; Gao Z, Xu Y, Sun C, Wang X, Guo Y, Qiu S, Ma K. A systematic review of asymptomatic infections with COVID-19. J Microbiol Immunol Infect. 2021 Feb;54(1):12-6. DOI:10.1016/j.jmii.2020.05.001; Instituto Brasileiro de Geografia e Estatística (IBGE). 2020. https://cidades.ibge.gov.br/brasil/sp/uru/panorama; Justo AFO, Bueno MS, Barbosa GR, Perosa AH, Carvalho JM, Bellei N. Comparison of viral load between saliva and nasopharyngeal swabs for SARS-CoV2: the role of days of symptoms onset on diagnosis. Mem Inst Oswaldo Cruz. 2021;116:e210018. DOI:10.1590/0074-02760210018; Konishi Y, Saito T, Ishikawa T, Kanai H, Igei N. How Did Japan Cope with COVID-19? Big Data and Purchasing Behavior. Asian Econ Papers. 2021 Apr 24;20(1):146-67. DOI:10.1162/asep_a_00797; Kramer A, Eggers M, Hübner NO, Walger P, Steinmann E, Exner M. Virucidal gargling and virucidal nasal spray. GMS Hyg Infect Control. 2021 Jan 18;16:Doc02. DOI:10.3205/dgkh000373; Martínez Lamas L, Diz Dios P, Pérez Rodríguez MT, Del Campo Pérez V, Cabrera Alvargonzalez JJ, López Domínguez AM, Fernandez Feijoo J, Diniz Freitas M, Limeres Posse J. Is povidone iodine mouthwash effective against SARS-CoV-2? First in vivo tests. Oral Dis. 2022 04;28 Suppl 1:908-11. DOI:10.1111/odi.13526; Mateos-Moreno MV, Mira A, Ausina-Márquez V, Ferrer MD. Oral antiseptics against coronavirus: in-vitro and clinical evidence. J Hosp Infect. 2021 Jul;113:30-43. DOI:10.1016/j.jhin.2021.04.004; Matuck BF, Dolhnikoff M, Duarte-Neto AN, Maia G, Gomes SC, Sendyk DI, Zarpellon A, de Andrade NP, Monteiro RA, Pinho JRR, Gomes-Gouvêa MS, Souza SC, Kanamura C, Mauad T, Saldiva PHN, Braz-Silva PH, Caldini EG, da Silva LFF. Salivary glands are a target for SARS-CoV-2: a source for saliva contamination. J Pathol. 2021 07;254(3):239-43. DOI:10.1002/path.5679; Mohamed NA, Baharom N, Sulaiman WSW, Rashid ZZ, et al. Early viral clearance among covid-19 patients when gargling with povidone-iodine and essential oils: a pilot clinical trial [Preprint]. medRxiv. 2020 Sep 09. DOI:10.1101/2020.09.07.20180448; Nagatake T, Ahmed K, Oishi K. Prevention of respiratory infections by povidone-iodine gargle. Dermatology. 2002;204 Suppl 1:32-6. DOI:10.1159/000057722; Orcina BF, Santos PSSS. Oral manifestation COVID-19 and the rapid resolution of symptoms post-phtalox treatment: a case series. Int J Odontostomat. 2021;15(1):67-70.; Peng X, Xu X, Li Y, Cheng L, Zhou X, Ren B. Transmission routes of 2019-nCoV and controls in dental practice. Int J Oral Sci. 2020 03;12(1):9. DOI:10.1038/s41368-020-0075-9; Santos C, da Fonseca Orcina B, Brito Reia VC, Ribeiro LG, Grotto RMT, Prudenciatti A, de Moraes LN, Ragghianti Zangrando M, Vilhena FV, da Silva Santos PS. Virucidal Activity of the Antiseptic Mouthwash and Dental Gel Containing Anionic Phthalocyanine Derivative: In vitro Study. Clin Cosmet Investig Dent. 2021;13:269-74. DOI:10.2147/CCIDE.S315419; Tashiro A, Shaw R. COVID-19 Pandemic response in Japan: what is behind the initial flattening of the curve? Sustainability. 2020;12(13):5250. DOI:10.3390/su12135250; Teodoro G, Santos C, Campos MA, Koga-ito C, Sibelino S, Vilhena F. PHTALOX® antimicrobial action and cytotoxicity: in vitro study. In: 2020 IADR/AADR/CADR General Session, Washington, D.C., USA. 2020. Abstract number 0839. Available from: https://iadr.abstractarchives.com/abstract/20iags-3314903/phtalox-antimicrobial-action-and-cytotoxicity-in-vitro-study; To KK, Tsang OT, Yip CC, Chan KH, Wu TC, Chan JM, Leung WS, Chik TS, Choi CY, Kandamby DH, Lung DC, Tam AR, Poon RW, Fung AY, Hung IF, Cheng VC, Chan JF, Yuen KY. Consistent Detection of 2019 Novel Coronavirus in Saliva. Clin Infect Dis. 2020 07;71(15):841-3. DOI:10.1093/cid/ciaa149; Vietnam Health Environment Management Agency (VIHEMA). Communication on disease prevention and control - COVID-19. [cited 2021 Feb 12]. Available from: https://vihema.gov.vn; Vilhena FV, Brito Reia VC, da Fonseca Orcina B, Santos CA, Zangrando M, Cardoso de Oliveira R, da Silva Santos PS. The use of antiviral Phthalocyanine mouthwash as a preventive measure against COVID-19. GMS Hyg Infect Control. 2021 Jul 9;16:Doc24. DOI:10.3205/dgkh000395; World Health Organization. Coronavirus disease (COVID-19): situation report. 2020. Available from: https://www.who.int/docs/default-source/coronaviruse/covid-strategy-update-14april2020.pdf; Wu F, Zhao S, Yu B, Chen YM, Wang W, Song ZG, Hu Y, Tao ZW, Tian JH, Pei YY, Yuan ML, Zhang YL, Dai FH, Liu Y, Wang QM, Zheng JJ, Xu L, Holmes EC, Zhang YZ. A new coronavirus associated with human respiratory disease in China. Nature. 2020 03;579(7798):265-9. DOI:10.1038/s41586-020-2008-3; http://dx.doi.org/10.3205/dgkh000426; http://nbn-resolving.de/urn:nbn:de:0183-dgkh0004261; http://www.egms.de/en/journals/dgkh/2022-17/dgkh000426.shtml

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