المؤلفون: Sang Hoon Han (14426), Christopher M. Goins (3847540), Tarun Arya (466860), Woo-Jin Shin (1992154), Joshua Maw (11232595), Alice Hooper (4325923), Dhiraj P. Sonawane (11232598), Matthew R. Porter (11232601), Breyanne E. Bannister (11232604), Rachel D. Crouch (4743162), A. Abigail Lindsey (11232607), Gabriella Lakatos (509406), Steven R. Martinez (2182504), Joseph Alvarado (1783765), Wendell S. Akers (11232610), Nancy S. Wang (11232613), Jae U. Jung (9611629), Jonathan D. Macdonald (5466407), Shaun R. Stauffer (1309554)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Infectious Diseases, Virology, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, SARS-CoV -2 3 CL, Antiviral activity, CCF, ML 300-based inhibitors, plaque formation assay, Structure-Based Optimization, future SARS-like zoonotic coronavir., X-ray structures, vivo probes, Severe Acute Respiratory Syndrome C., nanomolar activity, syndrome coronavirus, noncanonical binding mode, noncovalent mode, SARS-CoV -2-infected Vero E 6 cell ., DMPK, Compound 41, MLPCN, peptidic 3 CL, probe compound 41, structure-based optimization campaign, ML 300-Derived Noncovalent Inhibito.

Relation: https://figshare.com/articles/journal_contribution/Structure-Based_Optimization_of_ML300-Derived_Noncovalent_Inhibitors_Targeting_the_Severe_Acute_Respiratory_Syndrome_Coronavirus_3CL_Protease_SARS-CoV_2_3CL_sup_pro_sup_/15109087

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00598.s001

المؤلفون: Sang Hoon Han (14426), Christopher M. Goins (3847540), Tarun Arya (466860), Woo-Jin Shin (1992154), Joshua Maw (11232595), Alice Hooper (4325923), Dhiraj P. Sonawane (11232598), Matthew R. Porter (11232601), Breyanne E. Bannister (11232604), Rachel D. Crouch (4743162), A. Abigail Lindsey (11232607), Gabriella Lakatos (509406), Steven R. Martinez (2182504), Joseph Alvarado (1783765), Wendell S. Akers (11232610), Nancy S. Wang (11232613), Jae U. Jung (9611629), Jonathan D. Macdonald (5466407), Shaun R. Stauffer (1309554)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Infectious Diseases, Virology, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, SARS-CoV -2 3 CL, Antiviral activity, CCF, ML 300-based inhibitors, plaque formation assay, Structure-Based Optimization, future SARS-like zoonotic coronavir., X-ray structures, vivo probes, Severe Acute Respiratory Syndrome C., nanomolar activity, syndrome coronavirus, noncanonical binding mode, noncovalent mode, SARS-CoV -2-infected Vero E 6 cell ., DMPK, Compound 41, MLPCN, peptidic 3 CL, probe compound 41, structure-based optimization campaign, ML 300-Derived Noncovalent Inhibito.

Relation: https://figshare.com/articles/dataset/Structure-Based_Optimization_of_ML300-Derived_Noncovalent_Inhibitors_Targeting_the_Severe_Acute_Respiratory_Syndrome_Coronavirus_3CL_Protease_SARS-CoV_2_3CL_sup_pro_sup_/15109090

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00598.s002