نتائج البحث - "A(2A) receptor"

المساهمون: Lille Neurosciences & Cognition - U 1172 (LilNCog), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Excellence Laboratory LabEx DISTALZ, Laboratoire de neurosciences cognitives et adaptatives (LNCA), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 (RID-AGE), Institut Pasteur de Lille, Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), Plateformes Lilloises en Biologie et Santé - UAR 2014 - US 41 (PLBS), Pasteur Network (Réseau International des Instituts Pasteur)-Pasteur Network (Réseau International des Instituts Pasteur)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U 1192 (PRISM), Centre Hospitalier Universitaire Vaudois = Lausanne University Hospital Lausanne (CHUV), Université de Lausanne = University of Lausanne (UNIL), Institut du Fer à Moulin (IFM - Inserm U1270 - SU), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Laboratoire des Maladies Neurodégénératives - UMR 9199 (LMN), Molecular Imaging Research Center Fontenay-aux-Roses (MIRCEN), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Universidade de Lisboa = University of Lisbon = Université de Lisbonne (ULISBOA)

المصدر: ISSN: 0006-8950.

مصطلحات موضوعية: adenosine, A(2A) receptor, Alzheimer's disease, Synapse loss, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/38964748; PUBMED: 38964748; PUBMEDCENTRAL: PMC11292904

الاتاحة: https://hal.univ-lille.fr/hal-04684882
https://hal.univ-lille.fr/hal-04684882v1/document
https://hal.univ-lille.fr/hal-04684882v1/file/awae113.pdf
https://doi.org/10.1093/brain/awae113

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5

Academic Journal

Molecular Dynamics (MD) Simulations Provide Insights into the Activation Mechanisms of 5-HT2A Receptors

المؤلفون: Meng Cui, Yongcheng Lu, Mihaly Mezei, Diomedes E. Logothetis

المصدر: Molecules ; Volume 29 ; Issue 20 ; Pages: 4935

مصطلحات موضوعية: G-protein-coupled receptor (GPCR), 5HT 2A receptor, MD simulations, protein−ligand interactions, receptor activation, conformational changes

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules29204935

الاتاحة: https://doi.org/10.3390/molecules29204935

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6

Academic Journal

A role for the serotonin 2A receptor in the expansion and functioning of human transmodal cortex.

المؤلفون: Luppi, Andrea I, Girn, Manesh, Rosas, Fernando E, Timmermann, Christopher, Roseman, Leor, Erritzoe, David, Nutt, David J, Stamatakis, Emmanuel A, Spreng, R Nathan, Xing, Lei, Huttner, Wieland B, Carhart-Harris, Robin L

مصطلحات موضوعية: cortical expansion, cortical functional organization, neurodevelopment, psychedelics, serotonin 2A receptor, transmodal cortex, Adult, Humans, Brain, Cerebral Cortex, Cognition, Neuroimaging, Receptor, Serotonin, 5-HT2A

وصف الملف: Print; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/375376; https://doi.org/10.17863/CAM.113090

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/375376
https://doi.org/10.17863/CAM.113090

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7

Academic Journal

Psychedelic-like Activity of Norpsilocin Analogues

المؤلفون: Alexander M. Sherwood, Elise K. Burkhartzmeyer, Samuel E. Williamson, Michael H. Baumann, Grant C. Glatfelter

Relation: https://figshare.com/articles/journal_contribution/Psychedelic-like_Activity_of_Norpsilocin_Analogues/24961371

الاتاحة: https://doi.org/10.1021/acschemneuro.3c00610.s001
https://figshare.com/articles/journal_contribution/Psychedelic-like_Activity_of_Norpsilocin_Analogues/24961371

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8

Academic Journal

Antagonists of the adenosine A(2A) receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5-and C7-positions to enhance affinity

المؤلفون: Duroux, Romain, Agouridas, Laurence, Renault, Nicolas, El Bakali, Jamal, Furman, Christophe, Melnyk, Patricia, Yous, Said

المساهمون: CHU Lille, Inserm, Université de Lille, Lille Neurosciences & Cognition (LilNCog) - U 1172, Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 JPArc, Institut de Recherche Translationnelle sur l'Inflammation (INFINITE) - U1286, 498252|||Lille Inflammation Research International Center - U 995 LIRIC (OLD), Lille Inflammation Research International Center (LIRIC) - U995, Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 RID-AGE

مصطلحات موضوعية: Neurodegenerative disease, Benzoxazole, A(2A) receptor, DMPK

وصف الملف: application/octet-stream

Relation: European Journal of Medicinal Chemistry; Eur. J. Med. Chem.; http://hdl.handle.net/20.500.12210/40412

الاتاحة: https://hdl.handle.net/20.500.12210/40412

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9

Academic Journal

Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure

المؤلفون: Boulahjar, Rajaa, Rincon Arias, Angela, Bolteau, Raphael, Renault, Nicolas, Coevoet, Mathilde, Barczyk, Amélie, Duroux, Romain, Yous, Said, Melnyk, Patricia, Agouridas, Laurence

المساهمون: CHU Lille, Inserm, Université de Lille, Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 JPArc, Lille Inflammation Research International Center - U 995 LIRIC

مصطلحات موضوعية: Amino-imidazopyridine, Privileged structure, Palladium-catalyzed coupling reaction, A(2A) receptor

وصف الملف: application/octet-stream

Relation: Bioorganic & medicinal chemistry; Bioorg. Med. Chem.; http://hdl.handle.net/20.500.12210/104897

الاتاحة: https://hdl.handle.net/20.500.12210/104897

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10

Academic Journal

Radiosynthesis and In Vitro Evaluation of [ 11 C]tozadenant as Adenosine A 2A Receptor Radioligand

المؤلفون: Swen Humpert, Daniela Schneider, Markus Lang, Annette Schulze, Felix Neumaier, Marcus Holschbach, Dirk Bier, Bernd Neumaier

المصدر: Molecules, Vol 29, Iss 5, p 1089 (2024)

مصطلحات موضوعية: adenosine A 2A receptor, carbon-11, positron emission tomography, tozadenant, radiolabeling, Organic chemistry, QD241-441

Relation: https://www.mdpi.com/1420-3049/29/5/1089; https://doaj.org/toc/1420-3049; https://doaj.org/article/13659766cc3a4cf2ae1b446a114dad6e

الاتاحة: https://doi.org/10.3390/molecules29051089
https://doaj.org/article/13659766cc3a4cf2ae1b446a114dad6e

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11

Academic Journal

Adenosine A 2A Receptor Blockade Provides More Effective Benefits at the Onset Rather than after Overt Neurodegeneration in a Rat Model of Parkinson’s Disease

المؤلفون: Ana Carla L. Nunes, Marta Carmo, Andrea Behrenswerth, Paula M. Canas, Paula Agostinho, Rodrigo A. Cunha

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 9, p 4903 (2024)

مصطلحات موضوعية: adenosine, A 2A receptor, Parkinson’s disease, synapse, striatum, substantia nigra, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/9/4903; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/9fd4d223dd634e1eb1dfdbe7c500495b

الاتاحة: https://doi.org/10.3390/ijms25094903
https://doaj.org/article/9fd4d223dd634e1eb1dfdbe7c500495b

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12

Academic Journal

Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d -lysergic acid diethylamide (LSD)

المؤلفون: Halberstadt, Adam L, Chatha, Muhammad, Klein, Adam K, McCorvy, John D, Meyer, Markus R, Wagmann, Lea, Stratford, Alexander, Brandt, Simon D

مصطلحات موضوعية: Biological Psychology, Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Psychology, Neurosciences, Prevention, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Animals, Behavior, Animal, Binding, Competitive, Biotransformation, Calcium Signaling, Drug Evaluation, Preclinical, Hallucinogens, Lysergic Acid Diethylamide, Male, Mice, Mice, Inbred C57BL, Prodrugs, Rats, Rats, Sprague-Dawley, Receptors, Serotonin, 5-HT2, Serotonin 5-HT2 Receptor Agonists, Serotonin 5-HT2 Receptor Antagonists, New psychoactive substances, LSD, 5-HT2A receptor, Lysergamides, Psychedelics, 5-HT(2A) receptor, Neurology & Neurosurgery, Pharmacology and pharmaceutical sciences, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/25k3n6sg

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13

Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?

المؤلفون: Ballante, Flavio, Kooistra, Albert J., Kampen, Stefanie, de Graaf, Chris, Carlsson, Jens

المصدر: Pharmacological Reviews. 73(4):527-565

مصطلحات موضوعية: STRUCTURE-BASED DISCOVERY, ADENOSINE A(2A) RECEPTOR, STRUCTURE-BASED PREDICTION, KAPPA-OPIOID RECEPTOR, FRAGMENT-LIKE LIGANDS, CRYSTAL-STRUCTURE, DRUG DISCOVERY, BETA(2)-ADRENERGIC RECEPTOR, ALLOSTERIC MODULATORS, INTERNATIONAL UNION

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-466527
https://doi.org/10.1124/pharmrev.120.000246
https://uu.diva-portal.org/smash/get/diva2:1633120/FULLTEXT01.pdf

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14

Academic Journal

The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice

المؤلفون: Vladimir M. Pogorelov, Ramona M. Rodriguiz, Bryan L. Roth, William C. Wetsel

المصدر: Frontiers in Molecular Biosciences, Vol 10 (2023)

مصطلحات موضوعية: lisuride, β-arrestin, serotonin 2A receptor, mice, prepulse inhibition, head twitch, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1233743/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/59f60518aad045a08b4c3d8cae89d31e

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15

Academic Journal

Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran (“FLY”) and benzodifuran (“DragonFLY”) analogs

المؤلفون: Halberstadt, Adam L, Chatha, Muhammad, Stratford, Alexander, Grill, Matthias, Brandt, Simon D

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9724x2hb

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16

Academic Journal

Role of adenosine A2A receptors in hot and cold cognition: Effects of single-dose istradefylline in healthy volunteers

المؤلفون: Hook, R.W., Isobe, M., Savulich, G., Grant, J.E., Ioannidis, K., Christmas, D., Sahakian, B.J., Robbins, T.W., Chamberlain, S.R.

المصدر: Hook , R W , Isobe , M , Savulich , G , Grant , J E , Ioannidis , K , Christmas , D , Sahakian , B J , Robbins , T W & Chamberlain , S R 2023 , ' Role of adenosine A2A receptors in hot and cold cognition: Effects of single-dose istradefylline in healthy volunteers ' , European Neuropsychopharmacology , vol. 71 , no. 1 , pp. 55-64 . https://doi.org/10.1016/j.euroneuro.2023.03.006

مصطلحات موضوعية: Istradefylline, Cognition, Adenosine, DEFICIT HYPERACTIVITY DISORDER, A(2A) RECEPTOR, ANTAGONIST ISTRADEFYLLINE, CAFFEINE CONSUMPTION, MEMORY, DYSFUNCTION, METHYLPHENIDATE, SYNAPTOTOXICITY, IMPULSIVENESS, FLEXIBILITY