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    Academic Journal
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    Academic Journal

    المساهمون: S. Gallo, S. Locarno, E. Brambilla, C. Lenardi, E. Pignoli, I. Veronese

    مصطلحات موضوعية: A double network hydrogel based on Poly(vinyl-alcohol) (PVA) cross-linked with Glutaraldehyde (GTA) was recently developed by using self-assembling phenylalanine (Phe) peptide derivative (Fmoc-Phe-Phe-OMe), with the aim to improve the mechanical-elastic properties of PVA-GTA hydrogels. In this study, a characterization of the properties of Xylenol Orange based Fricke gel dosimeters obtained by infusing a Fricke solution into the double network hydrogel was performed. The gel dosimeters were irradiated with 6 MV and 15 MV X-rays produced by a medical linear accelerator and investigated by means optical absorbance measurements. The double network hydrogel formulation maintained a satisfactory level of radiological water-equivalence within the investigated radiotherapy range. Fricke gel dosimeters prepared with such network kept the desired properties of independence of the response of the dose rate and energy in the investigated intervals. Furthermore, the addition of self-assembling Phe peptide derivative proved not avoid the motion of radio-inducted ferric ions into the hydrogel, probably maintaining the main characteristics of the standard, no Phe peptide infused, formulation. The time course of formation of the optical response after the irradiation was observed to be similar to what previously measured in traditional PVA-GTA Fricke gel dosimeters, while a decrease of the sensitivity to radiation dose of the order of 30% was found. The extent of the decrease does not seem such as to impair the use of these dosimeters for evaluation of doses typical of radiation therapy applications., Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin), Settore MED/36 - Diagnostica per Immagini e Radioterapia, Settore CHIM/06 - Chimica Organica

    Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001105080600001; volume:2024; issue:57; firstpage:1; lastpage:11; numberofpages:11; journal:JOURNAL OF PHYSICS. D, APPLIED PHYSICS; https://hdl.handle.net/2434/1018368; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85177977918; https://iopscience.iop.org/article/10.1088/1361-6463/ad0987

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    Academic Journal

    المساهمون: Seong Soo Shin, Sohyun Ahn, Seung-Hyup Baek, Jungwon Kwak, Jin Sung Kim, Woo Sang Ahn, Kim, Jinsung

    وصف الملف: application/pdf

    Relation: IN VIVO; J01043; OAK-2022-05520; https://ir.ymlib.yonsei.ac.kr/handle/22282913/191189; T202205137; IN VIVO, Vol.36(1) : 465-472, 2022-01

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    Dissertation/ Thesis
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    المصدر: Indian Journal of Pure & Applied Physics (IJPAP); Vol 60, No 9 (2022): Indian Journal of Pure & Applied Physics; 773-782

    وصف الملف: application/pdf

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