نتائج البحث - "3D HUMAN LIVER"

المصدر: Jiang , J , Pieterman , C D , Ertaylan , G , Peeters , R L M & de Kok , T M C M 2019 , ' The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro ' , Archives of Toxicology , vol. 93 , no. 11 , pp. 3067-3098 . https://doi.org/10.1007/s00204-019-02585-5

مصطلحات موضوعية: Drug-induced hepatotoxicity, In vitro human liver model, Omics approaches, Bioinformatics, Graphical Gaussian networks, Bayesian networks, PRIMARY HUMAN HEPATOCYTES, ON-A-CHIP, GENE-EXPRESSION PROFILES, PLURIPOTENT STEM-CELLS, 3D HUMAN LIVER, IPSC-DERIVED HEPATOCYTES, SET ENRICHMENT ANALYSIS, TIME-SERIES ANALYSIS, OXIDATIVE STRESS, HEPG2 CELLS

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/ba95e5ed-aa1c-4163-88a0-3be2ab60e433
https://doi.org/10.1007/s00204-019-02585-5

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4

Use of 3D Human Liver Organoids to Predict Drug-Induced Phospholipidosis

المؤلفون: Han-Byul Lee, Woo-Chan Son, Hyo-Jeong Han, Sang-Joon Lee, Ji-Young Lee, Eun-Ho Cho, Hee Seon Lim, Ju-Hyung Seok

المصدر: International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2982, p 2982 (2020)

مصطلحات موضوعية: 0301 basic medicine, HepG2, Cell Survival, 3D human liver organoids, Gene Expression, Vacuole, Lamellar granule, Lipidoses, Catalysis, Article, lcsh:Chemistry, Inorganic Chemistry, Tissue Culture Techniques, 03 medical and health sciences, 0302 clinical medicine, In vivo, Lysosome, Albumins, medicine, Organoid, Humans, Secretion, Physical and Theoretical Chemistry, Cytotoxicity, lcsh:QH301-705.5, Molecular Biology, Spectroscopy, Phospholipids, Phospholipidosis, Chemistry, Organic Chemistry, General Medicine, Hep G2 Cells, drug-induced phospholipidosis, Immunohistochemistry, Computer Science Applications, Cell biology, Organoids, 030104 developmental biology, medicine.anatomical_structure, lcsh:Biology (General), lcsh:QD1-999, Liver, 030220 oncology & carcinogenesis, Disease Susceptibility, Biomarkers, Glycogen

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57bcfc96e24a4fbea980b5ea2fa3014
https://pubmed.ncbi.nlm.nih.gov/32340283

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5

Liver-Kidney-on-Chip To Study Toxicity of Drug Metabolites

المؤلفون: Theobald, J., Ghanem, A., Wallisch, P., Banaeiyan, Amin A, Andrade-Navarro, M. A., Taskova, K., Haltmeier, M., Kurtz, A., Becker, H., Reuter, S., Mrowka, R., Cheng, X. L., Wolfl, S.

المصدر: Acs Biomaterials Science & Engineering. 4(1):78-89

مصطلحات موضوعية: Biomaterials Science, Biomaterialvetenskap, organ-on-chip, liver-on-chip, kidney-on-chip, toxicity, drug metabolism, microfluidic, HepG2, 3d human liver, primary human hepatocytes, a-chip, cytotoxicity assay, epithelial-cells, dna-adducts, hepg2 cells, culture, nephrotoxicity, cancer

URL الوصول: https://gup.ub.gu.se/publication/264249

6

Report

Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model

المؤلفون: Kermanizadeh, Ali, Løhr, Mille, Roursgaard, Martin, Messner, Simon, Gunness, Patrina, Kelm, Jens M, Møller, Peter, Stone, Vicki, Loft, Steffen

مصطلحات موضوعية: 3D human liver microtissue, Engineered nanomaterials, Inflammation, Lipid peroxidation, Genotoxicity

Relation: http://www.particleandfibretoxicology.com/content/11/1/56

الاتاحة: http://www.particleandfibretoxicology.com/content/11/1/56

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7

Evaluation of dioxin induced transcriptomic responses in a 3D human liver microtissue model

المؤلفون: Tian, Mingming, Gou, Xiao, Zhang, Xiaowei, Messner, Catherine, Suter-Dick, Laura, Yan, Lu

مصطلحات موضوعية: 3D human liver microtissues, Stable system, TCDD, Time-series transcriptomics, Biological processes, Species-specific response, 500 - Naturwissenschaften

Relation: Environmental Research; https://doi.org/10.1016/j.envres.2022.112906; https://irf.fhnw.ch/handle/11654/33912

الاتاحة: https://irf.fhnw.ch/handle/11654/33912
https://doi.org/10.1016/j.envres.2022.112906

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8

Academic Journal

Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model

المؤلفون: Kermanizadeh, A., Løhr, M., Roursgaard, M., Messner, S., Gunness, P., Kelm, J.M., Møller, P., Stone, V., Loft, S.

مصطلحات موضوعية: 3D human liver microtissue, Engineered nanomaterials, Genotoxicity, Inflammation, Lipid peroxidation

Relation: https://repository.derby.ac.uk/item/9z371/hepatic-toxicology-following-single-and-multiple-exposure-of-engineered-nanomaterials-utilising-a-novel-primary-human-3d-liver-microtissue-model; https://doi.org/10.1186/s12989-014-0056-2; Kermanizadeh, A., Løhr, M., Roursgaard, M., Messner, S., Gunness, P., Kelm, J.M., Møller, P., Stone, V. and Loft, S. 2014. Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model. Particle and Fibre Toxicology. Vol 11 (Issue 1, Article: 56). https://doi.org/10.1186/s12989-014-0056-2

الاتاحة: https://doi.org/10.1186/s12989-014-0056-2

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