المؤلفون: Ennus K. Pathan (10585489), Bhaswati Ghosh (390334), Ananda Rao Podilapu (4400251), Suvarn S. Kulkarni (1447597)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Physiology, Biotechnology, Ecology, Immunology, Infectious Diseases, Plant Biology, Chemical Sciences not elsewhere classified, sugar 2- acetamido -4-amino, glycosidic bonds, synthesis, 1 Zwitterionic polysaccharides, AAT building blocks, 17 steps, tetrasaccharide unit, PS, stereoselective manner, vaccine carriers, Bacteroides fragilis zwitterionic p., Total Synthesis, one-pot S N 2 displacement, commensal bacteria, immunotherapeutic agents

Relation: https://figshare.com/articles/journal_contribution/Total_Synthesis_of_the_Repeating_Unit_of_Bacteroides_fragilis_Zwitterionic_Polysaccharide_A1/14401849

الاتاحة: https://doi.org/10.1021/acs.joc.0c02935.s001

المؤلفون: Tomoya Mashiko, Yuta Shingai, Jun Sakai, Shinya Adachi, Akinobu Matsuzawa, Shogo Kamo, Kazuyuki Sugita

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Cell Biology, Neuroscience, Physiology, Biotechnology, Evolutionary Biology, Sociology, Developmental Biology, Inorganic Chemistry, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, phenolic oxidative cyclization, optically active forms, longest linear sequence, featuring pentacyclic skeletons, (−)- cohlearol b, (−)- cochlearol b, enantioselective total syntheses, total syntheses, overall yield, 17 steps, 16 steps, (+)- ganocin

Relation: https://figshare.com/articles/journal_contribution/Enantioselective_Total_Syntheses_of_-Ganocin_A_and_-Cochlearol_B/24552277

الاتاحة: https://doi.org/10.1021/acs.orglett.3c03572.s001
https://figshare.com/articles/journal_contribution/Enantioselective_Total_Syntheses_of_-Ganocin_A_and_-Cochlearol_B/24552277

المؤلفون: Dane Holte (1347420), Meera Rao (1703761), Alexander Huters (10536327), Justin Simanis (10536330), Jean-Christophe Califano (10536333), Aaron Kempema (2248534), Jean-Noel Levy (2820736)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Genetics, Neuroscience, Pharmacology, Biotechnology, Developmental Biology, Science Policy, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, Potent Pyrrolobenzodiazepine Dimer, 17 steps, SG 3259, Significant effort, GMP conditions, gram-scale development, antibody conjugation, IND-enabling toxicological studies, PBD, ADC, linker drug SG 3259, linker drug, Reverse-Phase Purification, scale reverse-phase HPLC purification

Relation: https://figshare.com/articles/journal_contribution/Early_Development_Scale-Up_and_Reverse-Phase_Purification_of_a_Highly_Potent_Pyrrolobenzodiazepine_Dimer_SG3259_for_Use_in_Antibody_Drug_Conjugates/14384337

الاتاحة: https://doi.org/10.1021/acs.oprd.0c00497.s001