المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/16932183

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s008

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibition_of_IDO-1_in_BV-2_with_1-MT_and_INCB_24360_decreased_iNOS_and_TNF-_levels_/16932162

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s001

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/1-MT_and_INCB-24360_treatment_reduced_M1-like_macrophage_while_increased_M2-like_macrophage_in_BV-2_/16932165

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s002

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/1-MT_and_INCB_treatment_did_not_change_the_migrating_and_proliferating_capacity_of_RAW264_7_and_BV-2_/16932168

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s003

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibiting_IDO-1_with_INCB24360_suppresses_IFN-_induced_iNOS_and_TNF_increases_in_BV-2_cells_/16932171

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s004

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/1-MT_and_INCB-24360_treatment_reduced_M1-like_macrophage_while_increased_M2-like_macrophage_in_IFN-_induced_BV-2_/16932174

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s005

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/1-MT_and_INCB24360_treatment_reduced_NLRP3_expression_and_NLRP3_gene_transcription_in_BV-2_/16932177

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s006

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/1-MT_and_INCB24360_enhance_IL-1_secretion_in_BV-2_/16932180

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.s007

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibiting_IDO-1_with_INCB24360_or_1-MT_suppresses_IFN-_induced_iNOS_and_TNF_increases_in_RAW264_7_cells_/16932198

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g005

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/INCB24360_treatment_reduced_DTR-dextran_uptake_by_RAW264_7_and_BV-2_cells_/16932195

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g004

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/IDO-1_macrophages_microglia_reside_in_the_meninges_and_perivascular_space_of_the_human_and_mouse_brain_and_in_human_GBM_tissues_/16932186

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g001

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibition_of_IDO-1_with_1-MT_and_INCB24360_decreased_iNOS_and_TNF-_levels_/16932189

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g002

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibiting_IDO-1_with_1-MT_or_INCB24360_reduced_the_proportion_of_M1-like_but_not_M2-like_RAW264_7_cells_/16932192

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g003

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibiting_IDO-1_with_INCB24360_reduced_the_M1-like_macrophage_proportion_in_the_RAW264_7_cells_induced_by_IFN-_/16932201

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g006

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibiting_IDO-1_with_1-MT_or_INCB24360_reduced_DTR-dextran_uptake_by_RAW264_7_and_BV-2_cells_induced_by_IFN-_/16932204

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g007

المؤلفون: Rong Ji (1496803), Lixiang Ma (4006619), Xinyu Chen (47670), Renqiang Sun (1649389), Li Zhang (8200), Hexige Saiyin (141992), Wenshi Wei (11240373)

مصطلحات موضوعية: Cell Biology, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, might suppress overactivation, data collectively show, suppressed nlrp3 expression, immunosuppressive enzyme expressed, human blood monocytes, 1 &# 946, ps1 mouse brains, incb24360 increased il, human brain tissues, 1 expressing macrophages, 1 expression, murine brains, mouse macrophages, brain immunity, expressed ido, dioxygenase 1, 1 reduced, subarachnoid space, phagocytic abilities, fluid uptake, filopodia growth, distribution pattern

Relation: https://figshare.com/articles/figure/Inhibiting_IDO-1_with_1-MT_or_INCB24360_reduced_NLRP3_expression_in_RAW264_7_cells_/16932207

الاتاحة: https://doi.org/10.1371/journal.pone.0258204.g008