نتائج البحث - "пептиды"

المساهمون: The authors declare that sequencing within the framework of this study was carried out with the support of JSC “Valenta Pharm”, without the participation of any employees or authorized representatives of this organization in the statistical analysis of the data obtained, the main part of the study, statistical analysis and preparation of the publication was carried out in the absence of external funding, Авторы декларируют, что секвенирование в рамках данного исследования было осуществлено при поддержке АО «Валента Фарм», без участия каких-либо сотрудников или уполномоченных данной организации в статистическом анализе полученных данных, проведение основной части исследования, статистический анализ и подготовка публикации осуществлены при отсутствии внешнего финансирования.

المصدر: Meditsinskiy sovet = Medical Council; № 1 (2024); 25–38 ; Медицинский Совет; № 1 (2024); 25–38 ; 2658-5790 ; 2079-701X

مصطلحات موضوعية: микробное разнообразие, antimicrobial peptides, bacteriocin-like peptides, gramicidin C, oropharyngeal microbiota, 16S sequencing, microbial diversity, острый тонзиллофарингит, острая респираторная инфекция, топическая этиотропная терапия, антимикробные пептиды, бактериоциноподобные пептиды, грамицидин С, микробиота ротоглотки, 16S секвенирование

وصف الملف: application/pdf

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Результаты комплексной оценки местной этиотропной терапии инфекционно-в оспалительных заболеваний глотки у детей дошкольного и младшего школьного возраста. Педиатрия. Consilium Medicum. 2023;(3):135–146. https://doi.org/10.26442/26586630.2023.3.202304.; Edouard S, Million M, Bachar D, Dubourg G, Michelle C, Ninove L et al. The nasopharyngeal microbiota in patients with viral respiratory tract infections is enriched in bacterial pathogens. Eur J Clin Microbiol Infect Dis. 2018;37(9):1725–1733. https://doi.org/10.1007/s10096-018-3305-8.; Thors V, Christensen H, Morales-Aza B, Oliver E, Sikora P, Vipond I et al. High-density Bacterial Nasal Carriage in Children Is Transient and Associated With Respiratory Viral Infections-Implications for Transmission Dynamics. Pediatr Infect Dis J. 2019;38(5):533–538. https://doi.org/10.1097/INF.0000000000002256.; DeMuri GP, Gern JE, Eickhoff JC, Lynch SV, Wald ER. Dynamics of Bacterial Colonization With Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis During Symptomatic and Asymptomatic Viral Upper Respiratory Tract Infection. Clin Infect Dis. 2018;66(7):1045–1053. https://doi.org/10.1093/cid/cix941.; Козырев ЕА, Бабаченко ИВ, Сидоренко СВ. Современные аспекты изучения респираторной микробиоты и ее роль в развитии инфекций нижних дыхательных путей. Инфекционные болезни. 2022;20(1):99–106. https://doi.org/10.20953/1729-9225-2022-1-99-106.; Elgamal Z, Singh P, Geraghty P. The Upper Airway Microbiota, Environmental Exposures, Inflammation, and Disease. Medicina (Kaunas). 2021;57(8):823. https://doi.org/10.3390/medicina57080823.; Santacroce L, Passarelli PC, Azzolino D, Bottalico L, Charitos IA, Cazzolla AP et al. Oral microbiota in human health and disease: A perspective. Exp Biol Med (Maywood). 2023;248(15):1288–1301. https://doi.org/10.1177/15353702231187645.; Степанова ТЮ, Тимофеева АВ. 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Lantibiotics, class I bacteriocins from the genus Bacillus. J Microbiol Biotechnol. 2011;21(3):229–235. Available at: https://pubmed.ncbi.nlm.nih.gov/21464591.; Miljkovic M, Jovanovic S, O’Connor PM, Mirkovic N, Jovcic B, Filipic B et al. Brevibacillus laterosporus strains BGSP7, BGSP9 and BGSP11 isolated from silage produce broad spectrum multi-antimicrobials. PLoS ONE. 2019;14(5):e0216773. https://doi.org/10.1371/journal.pone.0216773.; Berditsch M, Afonin S, Reuster J, Lux H, Schkolin K, Babii O et al. Supreme activity of gramicidin S against resistant, persistent and biofilm cells of staphylococci and enterococci. Sci Rep. 2019;9(1):17938. https://doi.org/10.1038/s41598-019-54212-z.; Shu Y, Upara C, Ding Q, Zhu M, Zeng E, Banas JA, Hong L. Spent culture supernatant of Streptococcus gordonii mitigates inflammation of human periodontal cells and inhibits proliferation of pathogenic oral microbes. J Periodontol. 2023;94(4):575–585. https://doi.org/10.1002/JPER.22-0333.; Kaci G, Goudercourt D, Dennin V, Pot B, Doré J, Ehrlich SD et al. Antiinflammatory properties of Streptococcus salivarius, a commensal bacterium of the oral cavity and digestive tract. Appl Environ Microbiol. 2014;80(3):928–934. https://doi.org/10.1128/AEM.03133-13.; Zhang G, Rudney JD. Streptococcus cristatus attenuates Fusobacterium nucleatum-induced cytokine expression by influencing pathways converging on nuclear factor-κB. Mol Oral Microbiol. 2011;26(2):150–163. https://doi.org/10.1111/j.2041-1014.2010.00600.x.; Козлов ИГ. Микробиота, мукозальный иммунитет и антибиотики: тонкости взаимодействия. РМЖ. 2018;26(8-1):19–27. Режим доступа: https://www.rmj.ru/articles/allergologiya/Mikrobiota_mukozalynyy_immunitet_iantibiotiki_tonkosti_vzaimodeystviya.; De Coster W, D’Hert S, Schultz DT, Cruts M, Van Broeckhoven C. NanoPack: visualizing and processing long-read sequencing data. Bioinformatics. 2018;34(15):2666–2669. https://doi.org/10.1093/bioinformatics/bty149.; Curry KD, Wang Q, Nute MG, Tyshaieva A, Reeves E, Soriano S et al. Emu: species-level microbial community profiling of full-length 16S rRNA Oxford Nanopore sequencing data. Nat Methods. 2022;19(7):845–853. https://doi.org/10.1038/s41592-022-01520-4.; Кройдер АС, Комарова МВ. Использование индексов биологического разнообразия для анализа микробиоты человека. Universum: медицина и фармакология. 2022;3(86):27–31. Режим доступа: https://7universum.com/ru/med/archive/item/13192. Kroider AS, Komarova MV. The use of biological diversity indices for the analysis of human microbiota. Universum: Medicine and Pharmacology. 2022;3(86):27–31. (In Russ.) Available at: https://7universum.com/ru/med/archive/item/13192.; Клименко ЕС, Белькова НЛ, Рычкова ЛВ, Даренская МА, Тугаринова ОА, Семенова НВ и др. Индексы альфа-разнообразия как показатели вариативности кишечной микробиоты у подростков разных этносов с ожирением. Бюллетень экспериментальной биологии и медицины. 2023;176(11):606–610. https://doi.org/10.47056/0365-9615-2023-176-11-606-610.; Haegeman B, Hamelin J, Moriarty J, Neal P, Dushoff J, Weitz JS. Robust estimation of microbial diversity in theory and in practice. ISME J. 2013;7(6):1092–1101. https://doi.org/10.1038/ismej.2013.10.; Pérez-Castro S, D’Auria G, Llambrich M, Fernández-B arrés S, Lopez-Espinosa MJ, Llop S et al. Influence of perinatal and childhood exposure to tobacco and mercury in children’s gut microbiota. Front Microbiol. 2024;14:1258988. https://doi.org/10.3389/fmicb.2023.1258988.; Odintsova VE, Klimenko NS, Tyakht AV. Approximation of a Microbiome Composition Shift by a Change in a Single Balance Between Two Groups of Taxa. mSystems. 2022;7(3):e0015522. https://doi.org/10.1128/msystems.00155-22.; Hou K, Wu ZX, Chen XY, Wang JQ, Zhang D, Xiao C et al. Microbiota in health and diseases. Signal Transduct Target Ther. 2022;7(1):135. https://doi.org/10.1038/s41392-022-00974-4.; Wen Z, Xie G, Zhou Q, Qiu C, Li J, Hu Q et al. Distinct Nasopharyngeal and Oropharyngeal Microbiota of Children with Influenza A Virus Compared with Healthy Children. Biomed Res Int. 2018;2018:6362716. https://doi.org/10.1155/2018/6362716.; Lee KH, Gordon A, Shedden K, Kuan G, Ng S, Balmaseda A, Foxman B. The respiratory microbiome and susceptibility to influenza virus infection. PLoS ONE. 2019;14(1):e0207898. https://doi.org/0.1371/journal.pone.0207898.; Skevaki CL, Tsialta P, Trochoutsou AI, Logotheti I, Makrinioti H, Taka S et al. Associations Between Viral and Bacterial Potential Pathogens in the Nasopharynx of Children With and Without Respiratory Symptoms. Pediatr Infect Dis J. 2015;34(12):1296–1301. https://doi.org/10.1097/INF.0000000000000872.; Hu Q, Dai W, Zhou Q, Fu D, Zheng Y, Wang W et al. Dynamic oropharyngeal and faecal microbiota during treatment in infants hospitalized for bronchiolitis compared with age-matched healthy subjects. Sci Rep. 2017;7(1):11266. https://doi.org/10.1038/s41598-017-11311-z.; Liu T, Chen YC, Jeng SL, Chang JJ, Wang JY, Lin CH et al. Short-term effects of Chlorhexidine mouthwash and Listerine on oral microbiome in hospitalized patients. Front Cell Infect Microbiol. 2023;13:1056534. https://doi.org/10.3389/fcimb.2023.1056534.; Сабанцева ЕГ, Дмитриева НА, Авраменко ЕА, Иванова ЕВ, Ежова ЕГ, Почивалин ВП. Оценка эффективности применения ополаскивателя, содержащего антисептик октенидина дигидрохлорид. Стоматология. 2021;100(2):32–39. https://doi.org/10.17116/stomat202110002132.; Sharma A, Singh P, Sarmah BK, Nandi SP. Quorum sensing: its role in microbial social networking. Res Microbiol. 2020;171(5-6):159–164. https://doi.org/10.17116/stomat20211000213210.1016/j.resmic.2020.06.003.; Wenzel M, Kohl B, Münch D, Raatschen N, Albada HB, Hamoen L et al. Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane. Antimicrob Agents Chemother. 2012;56(11):5749–5757. https://doi.org/10.1128/AAC.01380-12.; Захарова ИН, Геппе НА, Сугян НГ, Денисова АР, Бережная ИВ. Топические этиотропные препараты в терапии инфекционно-воспалительных заболеваний глотки у детей дошкольного возраста. Результаты многоцентрового рандомизированного клинического исследования. Российская оториноларингология. 2021;20(1):99–113. https://doi.org/10.18692/18104800-2021-1-102-117.; Радциг ЕЮ, Гуров АВ. Боль в горле. Перекрестье проблем и поиски решений. РМЖ. Мать и дитя. 2022;5(3):228–236. https://doi.org/10.32364/2618-8430-2022-5-3-228-236.; https://www.med-sovet.pro/jour/article/view/8074

الاتاحة: https://www.med-sovet.pro/jour/article/view/8074
https://doi.org/10.21518/ms2024-037

View record in BASE

4

Academic Journal

ПЕПТИДНЫЙ ОБОГАЩЕННЫЙ МОДУЛЬ ФУНКЦИОНАЛЬНОЙ НАПРАВЛЕННОСТИ ДЛЯ ПРОФИЛАКТИКИ ОЖИРЕНИЯ И ГИПЕРЛИПИДЕМИИ

المؤلفون: Антон Вадимович Табакаев, Оксана Вацлавовна Табакаева

المصدر: Ползуновский вестник, Iss 1 (2024)

مصطلحات موضوعية: ферментатиный гидролиз, пептиды, аминокислоты, цинк, таурин, двустворчатый моллюск Anadara broughtonii, Technology

وصف الملف: electronic resource

Relation: https://ojs.altstu.ru/index.php/PolzVest/article/view/545; https://doaj.org/toc/2072-8921

URL الوصول: https://doaj.org/article/b153af53bbf840fd91e48360f895378d

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5

Academic Journal

Principles of management of patients with short bowel syndrome ; Принципы ведения больных с синдромом короткой кишки

المؤلفون: V. S. Shemenkova, В. С. Шеменкова

المصدر: Meditsinskiy sovet = Medical Council; № 23 (2023); 144-148 ; Медицинский Совет; № 23 (2023); 144-148 ; 2658-5790 ; 2079-701X

مصطلحات موضوعية: кишечная недостаточность, malabsorption, glucagon-like peptides, teduglutide, water-electrolyte disorders, intestinal failure, мальабсорбция, глюкагоноподобные пептиды, тедуглутид, водно-электролитные нарушения

وصف الملف: application/pdf

Relation: https://www.med-sovet.pro/jour/article/view/8012/7104; Аверьянова ЮВ, Батыршин ИМ, Демко АЕ, Иванова ГЕ, Ивашкин ВТ, Костюченко ЛН и др. Синдром короткой кишки с кишечной недостаточностью у взрослых: клинические рекомендации. 2022. 106 с. Режим доступа: gastro.ru›userfiles/R_СиндрКорКишПРОЕКТ.pdf.; Сухотник ИГ. Синдром короткой кишки у детей. Российский вестник детской хирургии, анестезиологии и реаниматологии. 2017;7(3):99–116. Режим доступа: https://www.elibrary.ru/zxhmtn.; Никонов ЕЛ, Чубарова АИ, Аверьянова ЮВ, Полевиченко ЕВ, Скворцова ТА, Витковская ИП и др. Синдром короткой кишки у пациентов детского возраста. Текущее состояние проблемы и лечения пациентов в России. Доказательная гастроэнтерология. 2020;9(3):5–15. https://doi.org/10.17116/dokgastro202090315.; Jeppesen PB. The long road to the development of effective therapies for the short gut syndrome: a personal perspective. Dig Dis Sci. 2019;64(10):2717–2735. https://doi.org/10.1007/s10620-019-05779-0.; Парфенов АИ, Сабельникова ЕА, Кузьмина ТН. Синдром короткой кишки. Терапевтический архив. 2017;12(2):144–149. https://doi.org/10.17116/terarkh20178912144-149.; Pironi L, Arends J, Baxter J, Bozzetti F, Peláez RB, Cuerda C et al. ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults. Clin Nutr. 2015;34(2):171–180. https://doi.org/10.1016/j.clnu.2014.08.017.; Norsa L, Lambe C, Abi Abboud S, Barbot-Trystram L, Ferrari A, Talbotec C et al. The Colon as an Energy Salvage Organ for Children with Short Bowel Syndrome. Am J Clin Nutr. 2019;109(4):1112–1118. https://doi.org/10.1093/ajcn/nqy367.; Галеева ЗМ, Гималетдинова ИА, Абсалямова ЛР, Галиханов ВР, Белалова АФ, Гайнеева РГ. Синдром короткой кишки в общеклинической практике. Вестник современной клинической медицины. 2011;4(2):36–43. Режим доступа: https://vskmjournal.org/images/Files/Issues_Archive/2011/Issue_2/VSKM_2011_N_2_p36-43.pdf.; Луфт ВМ, Демко АЕ, Лейдерман ИН, Лапицкий АВ, Батыршин ЭМ, Сергеева АМ. Синдром короткой кишки у взрослых: диагностика и лечение. СПб.; 2023. 78 с. Режим доступа: https://vzk-life.ru/upload/iblock/de1/de1c012ac0e6788638431d251d2b6cb9.pdf?ysclid=lqgsrgok3k139441960.; Nightingale J, Woodward JM. Guidelines for management of patients with a short bowel. Gut. 2006;55(4):l–12. https://doi.org/10.1136/gut.2006.091108; Сосновская ЕВ. Cовременные возможности фармакотерапии пациентов с синдромом короткой кишки. Вестник СурГУ. Медицина. 2021;4(50):26–30. https://doi.org/10.34822/2304-9448-2021-4-26-30.; Kocoshis SA, Merritt R J, Hill S, Protheroe S, Carter BA, Horslen S et al. Safety and Efficacy of Teduglutide in Pediatric Patients with Intestinal Failure Due to Short Bowel Syndrome: A 24-Week, Phase III Study. JPEN J Parenter Enteral Nutr. 2019;44(4):621–631. https://doi.org/10.1002/jpen.1690.; Jeppesen PB, Pertkiewicz M, Messing B, Iyer K, Seidner DL, O’keefe SJD et al. Teduglutide Reduces Need for Parenteral Support Among Patients with Short Bowel Syndrome with Intestinal Failure. Gastroenterology. 2012;143(6):1473–1481.e3. https://doi.org/10.1053/j.gastro.2012.09.007.; Amiot A, Messing B, Corcos O, Yves P, Francisca J. Determinants of Home Parenteral Nutrition Dependence and Survival of 268 Patients with Non-Malignant Short Bowel Syndrome. Clin Nutr. 2013;32(3):368–374. https://doi.org/10.1016/j.clnu.2012.08.007.; Bioletto F, D’Eusebio Ch, Merlo F, Aimasso U, Ossola M, Pellegrini M et al. Efficacy of Teduglutide for parenteral support reduction in patients with short bowel syndrome: a systematic review and meta-analysis. Nutrients. 2022;14(4):796. https://doi.org/10.3390/nu14040796.; Harpain F, Schlager L, Hutterer E, Dawoud C, Kirchnawy S, Stift J et al. Teduglutide in short bowel syndrome patients: a way back to normal life? JPEN J Parenter Enteral Nutr. 2022;46(2):300–309. https://doi.org/10.1002/jpen.2272.; Drucker DJ. The discovery of GLP-2 and development of Teduglutide for short bowel syndrome. ACS Pharmacol Transl Sci. 2019;2(2):134–142. https://doi.org/10.1021/acsptsci.9b00016.; Lam K, Schwartz L, Batisti J, Iyer KR. Single-Center Experience with the Use of Teduglutide in Adult Patients with Short Bowel Syndrome. JPEN J Parenter Enteral Nutr. 2018;42(1):225–230. https://doi.org/10.1002/jpen.1011.; Premkumar MH, Soraisham A, Bagga N, Massieu LA, Maheshwari A. Nutritional management of short bowel syndrome. Clin Perinatol. 2022;49(2):557–572. https://doi.org/10.1016/j.clp.2022.02.016.; Bering J, DiBaise JK. Short bowel syndrome: complications and management. Nutr Clin Pract. 2023;38(1):46–58. https://doi.org/10.1002/ncp.10978.; Vaz Ch, Shannon M, Zaloom J. Short bowel syndrome with intestinal failure in adults. Nursing. 2023;53(6):29–35. https://doi.org/10.1097/01.nurse.0000927448.14302.ab.; https://www.med-sovet.pro/jour/article/view/8012

الاتاحة: https://www.med-sovet.pro/jour/article/view/8012
https://doi.org/10.21518/ms2023-490

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6

Academic Journal

The effect of the probiotic bacteria Akkermansia Muciniphila in intestinal homeostasis and dss-induced inflammation in mice ; Эффект введения пробиотической бактерии Akkermansia Muciniphila в норме и при DSS-индуцированном воспалении у мышей

المؤلفون: Sheynova A.D., Podosokorskaya O.A., Gubernatorova E.O.

المصدر: Russian Journal of Infection and Immunity; Vol 14, No 3 (2024); 564-568 ; Инфекция и иммунитет; Vol 14, No 3 (2024); 564-568 ; 2313-7398 ; 2220-7619

مصطلحات موضوعية: Akkermansia muciniphila, microbiota, inflammatory bowel disease, DSS colitis, probiotic, antimicrobial peptides, микробиота, воспаление кишечника, DSS колит, пробиотик, анимикробные пептиды

وصف الملف: application/pdf

Relation: https://iimmun.ru/iimm/article/view/17737/2000; https://iimmun.ru/iimm/article/downloadSuppFile/17737/137734; https://iimmun.ru/iimm/article/downloadSuppFile/17737/137735; https://iimmun.ru/iimm/article/view/17737

الاتاحة: https://iimmun.ru/iimm/article/view/17737
https://doi.org/10.15789/2220-7619-TEO-16882

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7

Academic Journal

Production of plant protein from seeds and cake of industrial hemp: Overview of processing methods for food industry ; Получение растительного белка из семян и жмыха промышленной конопли: обзор способов переработки для использования в пищевой промышленности

المؤلفون: D. I. Aleksanochkin, I. A. Fomenko, E. A. Alekseeva, I. M. Chernukha, N. G. Mashentseva, Д. И. Алексаночкин, И. А. Фоменко, Е. А. Алексеева, И. М. Чернуха, Н. Г. Машенцева

المصدر: Food systems; Vol 7, No 2 (2024); 188-197 ; Пищевые системы; Vol 7, No 2 (2024); 188-197 ; 2618-7272 ; 2618-9771 ; 10.21323/2618-9771-2024-7-2

مصطلحات موضوعية: биологически активные пептиды, hemp cake, oil, fiber, protein isolate, protein hydrolysates, biologically active peptides, жмых конопли, масло, клетчатка, изолят белка, гидролизаты белка

وصف الملف: application/pdf

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الاتاحة: https://www.fsjour.com/jour/article/view/480
https://doi.org/10.21323/2618-9771-2024-7-2-188-197

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8

Academic Journal

Application of therapeutic nucleic acids and RNA interference to create products for personalised medicine ; Применение терапевтических нуклеиновых кислот и интерференции РНК для создания средств персонализированной медицины

المؤلفون: I. P. Shilovskiy, G. B. Pasikhov, V. V. Smirnov, I. A. Kofiadi, M. V. Popova, P. A. Strueva, M. R. Khaitov, И. П. Шиловский, Г. Б. Пасихов, В. В. Смирнов, И. А. Кофиади, М. В. Попова, П. А. Струева, М. Р. Хаитов

المساهمون: The study was supported by the Russian Science Foundation (Grant No. 23-45-10031)., Исследование выполнено за счет гранта Российского научного фонда № 23-45-10031.

المصدر: Biological Products. Prevention, Diagnosis, Treatment; Том 24, № 2 (2024): Высокотехнологичные лекарственные препараты; 157-171 ; БИОпрепараты. Профилактика, диагностика, лечение; Том 24, № 2 (2024): Высокотехнологичные лекарственные препараты; 157-171 ; 2619-1156 ; 2221-996X

مصطلحات موضوعية: эффективность препаратов миРНК, RNA interference, small interfering RNA, siRNA, personalised medicine, RNA delivery systems, GalNAc, cell-penetrating peptides, clinical trials, safety of siRNA medicinal products, efficacy of siRNA medicinal products, интерференция РНК, малые интерферирующие РНК, миРНК, персонализированная медицина, системы доставки РНК, клеточнопроникающие пептиды, клинические исследования, безопасность препаратов миРНК

وصف الملف: application/pdf

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الاتاحة: https://www.biopreparations.ru/jour/article/view/575
https://doi.org/10.30895/2221-996X-2024-24-2-157-171

View record in BASE

9

Academic Journal

Study of Ridostin Pro and Poly(I:C) as adjuvants that enhance the immunogenicity of an antitumor vaccine ; Изучение Ридостина Про и Рoly(I:C) в качестве адъювантов, усиливающих иммуногенность противоопухолевой вакцины

المساهمون: The work had financial support of the Ministry of Science and Higher Education of the Russian Federation as part of the research “Creation and development of a bioresource collection of genetically and phenotypically characterized cell lines and primary human tumors”. Research registration No. 075-15-2021-1060., Работа выполнена при финансовой поддержке Министерства науки и высшего образования Российской Федерации в рамках научно-исследовательской работы № 075-15-2021-1060 «Создание и развитие биоресурсной коллекции генетически и фенотипически охарактеризованных клеточных линий и первичных опухолей человека».

المصدر: Siberian journal of oncology; Том 23, № 3 (2024); 86-99 ; Сибирский онкологический журнал; Том 23, № 3 (2024); 86-99 ; 2312-3168 ; 1814-4861

مصطلحات موضوعية: доклинические исследования, adjuvants, antigens, Ridostin, Poly(I:C), peptides, preclinical studies, адъюванты, антигены, Ридостин, пептиды

وصف الملف: application/pdf

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الاتاحة: https://www.siboncoj.ru/jour/article/view/3117
https://doi.org/10.21294/1814-4861-2024-23-3-86-99

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