يعرض 1 - 15 نتائج من 15 نتيجة بحث عن '"мультикиназные ингибиторы"', وقت الاستعلام: 0.47s تنقيح النتائج
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    Academic Journal

    المصدر: Сборник статей

    وصف الملف: application/pdf

    Relation: Актуальные вопросы современной медицинской науки и здравоохранения: сборник статей VIII Международной научно-практической конференции молодых учёных и студентов, Екатеринбург, 19-20 апреля 2023 г.; Ваганова, И. Ю. Опыт терапии распространенного гепатоцеллюлярного рака мультикиназными ингибиторами у пациентов со сниженным функциональным статусом (ECOG 2) / И. Ю. Ваганова, В. В. Петкау. - Текст электронный. // Актуальные вопросы современной медицинской науки и здравоохранения: сборник статей VIII Международной научно-практической конференции молодых учёных и студентов, Екатеринбург, 19-20 апреля 2023 г. – Екатеринбург : УГМУ, 2023. – C. 2133-2136.; http://elib.usma.ru/handle/usma/14336

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    Academic Journal

    المصدر: Meditsinskiy sovet = Medical Council; № 11 (2023); 10-17 ; Медицинский Совет; № 11 (2023); 10-17 ; 2658-5790 ; 2079-701X

    وصف الملف: application/pdf

    Relation: https://www.med-sovet.pro/jour/article/view/7663/6797; Бредер В.В., Базин И.С., Балахнин П.В., Виршке Э.Р., Косырев В.Ю., Ледин Е.В. и др. Практические рекомендации по лекарственному лечению больных злокачественными опухолями печени и желчевыводящей системы. Злокачественные опухоли. 2022;12(3s2-1):467–529. https://doi.org/10.18027/2224-5057-2022-12-3s2-467-529.; Каприн А.Д., Старинский В.В., Петрова Г.В. (ред.). Злокачественные новообразования в России в 2017 году (заболеваемость и смертность). М.: МНИОИ; 2018. 250 с. Режим доступа: https://glavonco.ru/upload/pages/cancer-register/statistika_zabol_2017.pdf.; Cheng A.L., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma. J Hepatol. 2022;76(4):862–873. https://doi.org/10.1016/j.jhep.2021.11.030.; Morse M.A., Sun W., Kim R., He A.R., Abada P.B., Mynderse M., Finn R.S. The Role of Angiogenesis in Hepatocellular Carcinoma. Clin Cancer Res. 2019;25(3):912–920. https://doi.org/10.1158/1078-0432.CCR-18-1254.; Bray F., Ferlay J., Soerjomataram I., Siegel R.L., Torre L.A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. https://doi.org/10.3322/caac.21492.; Hegde P.S., Wallin J.J., Mancao C. Predictive markers of anti-VEGF and emerging role of angiogenesis inhibitors as immunotherapeutics. Semin Cancer Biol. 2018;52(Pt 2):117–124. https://doi.org/10.1016/j.semcancer.2017.12.002.; Lu L.C., Hsu C., Shao Y.Y., Chao Y., Yen C.J., Shih I.L. et al. Differential OrganSpecific Tumor Response to Immune Checkpoint Inhibitors in Hepatocellular Carcinoma. Liver Cancer. 2019;8(6):480–490. https://doi.org/10.1159/000501275.; Kim H.S., Hong J.Y., Cheon J., Kim I., Kim C.G., Kang B. et al. Different organspecific response to nivolumab to determine the survival outcome of patients with advanced hepatocellular carcinoma (aHCC). J Clin Oncol. 2020;38(Suppl. 15):4584–4584. https://doi.org/10.1200/JCO.2020.38.15_suppl.4584.; Yoong K.F., McNab G., Hübscher S.G., Adams D.H. Vascular adhesion protein-1 and ICAM-1 support the adhesion of tumor-infiltrating lymphocytes to tumor endothelium in human hepatocellular carcinoma. J Immunol. 1998;160(8):3978–3988. https://doi.org/10.4049/jimmunol.160.8.3978.; Lee M.S., Ryoo B.Y., Hsu C.H., Numata K., Stein S., Verret W. et al. Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study. Lancet Oncol. 2020;21(6):808–820. https://doi.org/10.1016/S1470-2045(20)30156-X.; Fulgenzi C.A.M., Cheon J., D’Alessio A., Nishida N., Ang C., Marron T.U. et al. Reproducible safety and efficacy of atezolizumab plus bevacizumab for HCC in clinical practice: Results of the AB-real study. Eur J Cancer. 2022;175:204–213. https://doi.org/10.1016/j.ejca.2022.08.024.; Zhu A.X., Duda D.G., Sahani D.V., Jain R.K. HCC and angiogenesis: possible targets and future directions. Nat Rev Clin Oncol. 2011;8(5):292–301. https://doi.org/10.1038/nrclinonc.2011.30.; Motz G.T., Santoro S.P., Wang L.P., Garrabrant T., Lastra R.R., Hagemann I.S., et al. Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Nat Med. 2014;20(6):607–615. https://doi.org/10.1038/nm.3541.; Wallin J.J., Bendell J.C., Funke R., Sznol M., Korski K., Jones S. et al. Atezolizumab in combination with bevacizumab enhances antigenspecific T-cell migration in metastatic renal cell carcinoma. Nat Commun. 2016;7:12624. https://doi.org/10.1038/ncomms12624.; Chen D.S., Hurwitz H. Combinations of Bevacizumab With Cancer Immunotherapy. Cancer J. 2018;24(4):193–204. https://doi.org/10.1097/PPO.0000000000000327.; Herbst R.S., Soria J.C., Kowanetz M., Fine G.D., Hamid O., Gordon M.S. et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014;515(7528):563–567. https://doi.org/10.1038/nature14011.; Finn R.S., Bentley G., Britten C.D., Amado R., Busuttil R.W. Targeting vascular endothelial growth factor with the monoclonal antibody bevacizumab inhibits human hepatocellular carcinoma cells growing in an orthotopic mouse model. Liver Int. 2009;29(2):284–290. https://doi.org/10.1111/j.1478-3231.2008.01762.x.; Boige V., Malka D., Bourredjem A., Dromain C., Baey C., Jacques N. et al. Efficacy, safety, and biomarkers of single-agent bevacizumab therapy in patients with advanced hepatocellular carcinoma. Oncologist. 2012;17(8):1063–1072. https://doi.org/10.1634/theoncologist.2011-0465.; Siegel A.B., Cohen E.I., Ocean A., Lehrer D., Goldenberg A., Knox J.J. et al. Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. J Clin Oncol. 2008;26(18):2992–2928. https://doi.org/10.1200/JCO.2007.15.9947.; Thomas M.B., Garrett-Mayer E., Anis M., Anderton K., Bentz T., Edwards A. et al. A Randomized Phase II Open-Label Multi-Institution Study of the Combination of Bevacizumab and Erlotinib Compared to Sorafenib in the First-Line Treatment of Patients with Advanced Hepatocellular Carcinoma. Oncology. 2018;94(6):329–339. https://doi.org/10.1159/000485384.; Finn R.S., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma. N Engl J Med. 2020;382(20):1894–1905. https://doi.org/10.1056/NEJMoa1915745.; Finn R.S., Qin S., Ikeda M., Galle P.R., Ducreux M., Kim T.Y. et al. IMbrave150: Updated overall survival (OS) data from a global, randomized, open-label phase III study of atezolizumab (atezo) + bevacizumab (bev) versus sorafenib (sor) in patients (pts) with unresectable hepatocellular carcinoma (HCC). J Clin Oncol. 2021;39(Suppl. 3):267–267. https://doi.org/10.1200/JCO.2021.39.3_suppl.267.; De Franchis R., Bosch J., Garcia-Tsao G., Reiberger T., Ripoll C. Baveno VII – Renewing consensus in portal hypertension. J Hepatol. 2022;76(4):959–974. https://doi.org/10.1016/j.jhep.2021.12.022.; https://www.med-sovet.pro/jour/article/view/7663

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    Academic Journal

    المصدر: Meditsinskiy sovet = Medical Council; № 10 (2018); 12-16 ; Медицинский Совет; № 10 (2018); 12-16 ; 2658-5790 ; 2079-701X ; 10.21518/2079-701X-2018-10

    وصف الملف: application/pdf

    Relation: https://www.med-sovet.pro/jour/article/view/2527/2495; George S, Wang Q, Heinrich MC, Corless CL, Zhu M et.al. Efficacy and safety of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of imatinib and sunitinib: a multicenter phase II trial. J Clin Oncol, 2012, 30(19): 2401. Epub 2012 May 21.; Ben-Ami E, Barysauskas CM, von Mehren M, Heinrich MC, Corless CL et al. Long-term follow-up results of the multicenter phase II trial of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of standard tyrosine kinase inhibitor therapy. Ann Oncol, 2016 Sep, 27(9): 1794-9. Epub 2016 Jul 1.; Demetri GD, Reichardt P, Kang YK, Blay JY, Rutkowski P et al GRID study investigators. Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet, 2013, 381(9863): 295. Epub 2012 Nov 22.; Chun-Nan Yeh, Ming-Huang Chen, Yen-Yang Chen, Ching-Yao Yang, ChuehChuan Yen, et al. A phase II trial of regorafenib in patients with metastatic and/or a unresectable gastrointestinal stromal tumor harboring secondary mutations of exon 17. Oncotarget, 2017, 8(27): 44121-44130.; Grellety T, Kind M, Coindre J-M. Clinical activity of regorafenib in PDGFRA-mutated gastrointestinal stromal tumor. Future Sci OA, 2015 Nov 1, 1(4): FSO33. doi:10.4155/fso.15.33. eCollection 2015 Nov.; A randomised trial of Imatinib alternating with Regorafenib compared to Imatinib alone for the first line treatment of advanced gastrointestinal stromal tumor (GIST) (ALT GIST) ClinicalTrials.gov Identifier: NCT02365441.; Phase Ib study of sunitinib alternating with regorafenib in patients with metastatic and/or unresectable GIST (SURE) ClinicalTrials.gov Identifier: NCT02164240.; Phase II study of Regorafenib continuous dosing of regorafenib in patients with GISTs. ClinicalTrials.gov Identifier: NCT02889328.; Phase II Study of Regorafenib Continuous Dosing of Regorafenib in Patients With GISTs. ID Number: AMC1602. NCT Identifier: NCT02889328; Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST (REGISTRI). ClinicalTrials.gov Identifier: NCT02638766.; https://www.med-sovet.pro/jour/article/view/2527

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    Academic Journal

    المصدر: Head and Neck Tumors (HNT); № 3 (2013); 11-15 ; Опухоли головы и шеи; № 3 (2013); 11-15 ; 2411-4634 ; 2222-1468 ; 10.17650/2222-1468-2013-0-3

    وصف الملف: application/pdf

    Relation: https://ogsh.abvpress.ru/jour/article/view/12/14; Румянцев П.О., Ильин А.А., Румянцева У.В., Саенко В.А. Рак щитовидной железы. Современные подходы к диагностике и лечению. М.: ГЭОТАР-Медиа, 2009.; Durante C., Haddy N., Baudin E. et al. Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy. J Clin Endocrinol Metab 2006;8:2892–9.; Schlumberger M., Lacroix L., Russo D. et al. Defects in iodide metabolism in thyroid cancer and implications for the follow-up and treatment of patients. Nat Clin Pract Endocrinol Metab 2007;3:260–9.; Schlumberger M.J. Papillary and follicular thyroid carcinoma. N Engl J Med 1998;5:297–306. 5. Hodak S.P., Carty S.E. Radioiodineresistant differentiated thyroid cancer: hope for the future. Oncology 2009;9:775–6.; Capdevila J., Argiles G., RodriguezFrexinos V. et al. New approaches in the management of radioiodine-refractory thyroid cancer: the molecular targeted therapy era. Discov Med 2010;45:153–62.; https://ogsh.abvpress.ru/jour/article/view/12

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