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    المساهمون: The work was supported by the grant of the Russian Science Foundation No. 20-12-00175-p and conducted in “Ivanovo State University of Chemical Technology”, Работа выполнена при поддержке гранта Российского научного фонда № 20-12-00175-п на базе ФГБОУ ВО «Ивановский государственный химико-технологический университет»

    المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 16, No 6 (2024); 89-96 ; Неврология, нейропсихиатрия, психосоматика; Vol 16, No 6 (2024); 89-96 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2024-6

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    Relation: https://nnp.ima-press.net/nnp/article/view/2423/1759; Cyr AR, Huckaby LV, Shiva SS, Zuckerbraun BS. Nitric Oxide and Endothelial Dysfunction. Crit Care Clin. 2020 Apr;36(2):307-21. doi:10.1016/j.ccc.2019.12.009; Сарвилина ИВ, Громова ОА, Наумов АВ. Патобиохимические пути развития редоксдисбаланса при неврологических долгосрочных эффектах COVID-19 и роль хондроитина сульфата в восстановлении редокс-статуса. Неврология, нейропсихиатрия, психосоматика. 2021;13(5):109-15. doi:10.14412/2074-2711-2021-5-109-115; Старчина ЮА, Гришина ДА, Соколов ЕА, Парфенов ВА. Применение ингаляционного оксида азота (аппарат «Тианокс») у пациентов с умеренными когнитивными нарушениями. Неврология, нейропсихиатрия, психосоматика. 2023;15(6):64-70. doi:10.14412/2074-2711-2023-6-64-70; Торшин ИЮ, Громова ОА, Нечаева ГИ и др. Систематический анализ молекулярно-биологических механизмов поддержки хондроитина сульфатом метаболизма соединительной ткани. Неврология, нейропсихиатрия, психосоматика. 2021;13(1):154-62. doi:10.14412/2074-2711-2021-1-154-162; Mariotti F. Arginine supplementation and cardiometabolic risk. Curr Opin Clin Nutr Metab Care. 2020 Jan;23(1):29-34. doi:10.1097/MCO.0000000000000612; Abuzayan I, Turner SW. Changes in exhaled nitric oxide after ingestion of L-arginine in children: a pilot study. Pediatr Pulmonol. 2010 Mar;45(3):236-40. doi:10.1002/ppul.21110; Zinellu A, Mangoni AA. Arginine, Transsulfuration, and Folic Acid Pathway Metabolomics in Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis. Cells. 2023 Aug 30;12(17):2180. doi:10.3390/cells12172180; Durante W, Johnson FK, Johnson RA. Arginase: a critical regulator of nitric oxide synthesis and vascular function. Clin Exp Pharmacol Physiol. 2007 Sep;34(9):906-11. doi:10.1111/j.1440-1681.2007.04638.x; Sotgia S, Mangoni AA, Zoroddu S, et al. Higher scores of the Kessler Psychological Distress Scale (K10) are associated with lower serum ergothioneine and higher serum asymmetric dimethyl-l-arginine concentrations in a cohort of middle-aged and older adults. Clin Nutr ESPEN. 2024 Sep 28;64:107-13. doi:10.1016/j.clnesp.2024.09.023. Epub ahead of print.; Ivy JL. Inorganic Nitrate Supplementation for Cardiovascular Health. Methodist Debakey Cardiovasc J. 2019 Jul-Sep;15(3):200-6. doi:10.14797/mdcj-15-3-200; Rajendra A, Bondonno NP, Zhong L, et al. Plant but not animal sourced nitrate intake is associated with lower dementia-related mortality in the Australian Diabetes, Obesity, and Lifestyle Study. Front Nutr. 2024 Aug 21;11:1327042. doi:10.3389/fnut.2024.1327042; Bonilla Ocampo DA, Paipilla AF, Marin E, et al. Dietary Nitrate from Beetroot Juice for Hypertension: A Systematic Review. Biomolecules. 2018 Nov 2;8(4):134. doi:10.3390/biom8040134; Bahrami LS, Arabi SM, Feizy Z, Rezvani R. The effect of beetroot inorganic nitrate supplementation on cardiovascular risk factors: A systematic review and meta-regression of randomized controlled trials. Nitric Oxide. 2021 Oct 1;115:8-22. doi:10.1016/j.niox.2021.06.002. Epub 2021 Jun 11.; Kolb AF, Petrie L. Folate deficiency enhances the inflammatory response of macrophages. Mol Immunol. 2013 Jun;54(2):164-72. doi:10.1016/j.molimm.2012.11.012. Epub 2012 Dec 29.; Haloul M, Vinjamuri SJ, Naquiallah D, et al. Hyperhomocysteinemia and Low Folate and Vitamin B 12 Are Associated with Vascular Dysfunction and Impaired Nitric Oxide Sensitivity in Morbidly Obese Patients. Nutrients. 2020 Jul 7;12(7):2014. doi:10.3390/nu12072014; Ozerol E, Ozerol I, Gökdeniz R, et al. Effect of smoking on serum concentrations of total homocysteine, folate, vitamin B12, and nitric oxide in pregnancy: a preliminary study. Fetal Diagn Ther. 2004 MarApr;19(2):145-8. doi:10.1159/000075139; Stanger O, Weger M. Interactions of homocysteine, nitric oxide, folate and radicals in the progressively damaged endothelium. Clin Chem Lab Med. 2003 Nov;41(11):1444-54. doi:10.1515/CCLM.2003.222; Van Oostrom O, de Kleijn DP, Fledderus JO, et al. Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study. Cardiovasc Diabetol. 2009 Aug 25;8:47. doi:10.1186/1475-2840-8-47; Holven KB, Holm T, Aukrust P, et al. Effect of folic acid treatment on endothelium-dependent vasodilation and nitric oxide-derived end products in hyperhomocysteinemic subjects. Am J Med. 2001 May;110(7):536-42. doi:10.1016/s0002-9343(01)00696-9; Sharma VS, Pilz RB, Boss GR, Magde D. Reactions of nitric oxide with vitamin B 12 and its precursor, cobinamide. Biochemistry. 2003 Jul 29;42(29):8900-8. doi:10.1021/bi034469t; Manzanares W, Hardy G. Vitamin B12: the forgotten micronutrient for critical care. Curr Opin Clin Nutr Metab Care. 2010 Nov;13(6):662- 8. doi:10.1097/MCO.0b013e32833dfaec; Greenberg SS, Xie J, Zatarain JM, et al. Hydroxocobalamin (vitamin B12а) prevents and reverses endotoxin-induced hypotension and mortality in rodents: role of nitric oxide. J Pharmacol Exp Ther. 1995 Apr;273(1):257-65.; Adelakun SA, Ukwenya VO, Akintunde OW. Vitamin B 12 ameliorate Tramadol-induced oxidative stress, endocrine imbalance, apoptosis and NO/iNOS/NF-κB expression in Sprague Dawley rats through regulatory mechanism in the pituitary-gonadal axis. Tissue Cell. 2022 Feb;74:101697. doi:10.1016/j.tice.2021.101697. Epub 2021 Nov 25.; Gromova OA, Torshin IYu, Maiorova LA, et al. Bioinformatic and chemoneurocytological analysis of the pharmacological properties of vitamin B 12 and some of its derivatives. J Porphyrins Phthalocyanines. 2021;25(9):835- 42. doi:10.1142/S1088424621500644; Gromova OA, Maiorova LA, Salnikov DS, et al. Vitamin B 12 hydrophobic derivative exhibits bioactivity: biomedical and photophysical study. BioNanoScience. 2022;12:74-82. doi:10.1007/s12668-021-00916-4; Vu TT, Maiorova LA, Berezin DB, Koifman OI. Formation and study of nanostructured M-monolayers and LS-films of triphenylcorrole. Macroheterocycles. (2016;9:73-9. doi:10.6060/mhc151205m 27. Maiorova LA, Kobayashi N, Zyablov SV, et al. Magnesium Porphine Supermolecules and TwoDimensional Nanoaggregates Formed Using the Langmuir-Schaefer Technique. Langmuir. 2018 Aug 7;34(31):9322-9. doi:10.1021/acs.langmuir.8b00905. Epub 2018 Jul 26.; Valkova LA, Shabyshev LS, Borovkov NYu, et al. Supramolecular assembly formation in monolayers of tert-butyl substituted copper Phthalocyanine and Tetrabenzotriazaporphin. J Incl Phenom Macrocycl Chem. 1999;35:243-9. doi:10.1023/A:1008147031935; Maiorova LA, Koifman OI, Burmistrov VA, et al. 2D M-nanoaggregates in Langmuir layers of calamite mesogen. Protect Metals Phys Chem Surf. 2015;51:85-92. doi:10.1134/S2070205115010074; Ariga K, Nishikawa M, Mori T, et al. Selfassembly as a key player for materials nanoarchitectonics. Sci Technol Adv Mater. 2019;20:51-95. doi:10.1080/14686996.2018.1553108; Valkova L, Borovkov N, Pisani M, et al. Some features of the molecular assembly of copper porphyrazines. Mater Sci Engin. 2002;22(2):167-70. doi:10.1016/S0928- 4931(02)00166-2; Valkova LA, Glibin AS, Valli L. Quantitative analysis of compression isotherms of fullerene C60 Langmuir layers. Colloid J. 2008;70:6-11. doi:10.1134/S1061933X0801002X; Valkova L, Menelle A, Borovkov N, et al. Small-angle X-ray scattering and neutron reflectivity studies of Langmuir-Blodgett films of copper tetra-tert-butyl-azaporphyrines. J Appl Crystallogr. 2003;36:758-62. doi:10.1107/S0021889803004965; Valkova L, Betrencourt C, Hochapfel A, et al. Monolayer study of monensin and lasalocid in the gas state. Mol Cryst Liq Cryst Sci Technol. 1996;287:269-73. doi:10.1080/10587259608038763; Karlyuk MV, Krygin YuYu, Maiorova LA, et al. Formation of two-dimensional (M) and three-dimensional (V) nanoaggregates of substituted cobalt porphyrin in the Langmuir layers and Langmuir-Schaefer films. Russ Chem Bull. 2013;62:471-9. doi:10.1007/s11172-013-0066-5; Kharitonova NV, Maiorova LA, Koifman OI. Aggregation behavior of unsubstituted magnesium porphyrazine in monolayers at air-water interface and in Langmuir-Schaefer films. J Porphyr Phthalocyanines. 2018;22:509-20. doi:10.1142/S1088424618500505; Maiorova L, Kobayashi N, Salnikov D, et al. Supermolecular nanoentities of vitamin B 12 derivative as a link in the evolution of the parent molecules during self-assembly at the air-water interface. Langmuir. 2023;39:3246-54. doi:10.1021/acs.langmuir.2c02964; Maiorova LA, Gromova OA, Torshin IYu, et al. Nanoparticles of nucleotide-free analogue of vitamin B 12 formed in protein nanocarriers and their neuroprotective activity in vivo. Colloids Surf B: Biointerfaces. 2024;244:114165. doi:10.1016/j.colsurfb.2024.114165; Akaike A, Tamura Y, Sato Y, Yokota T. Protective effects of a vitamin B 12 analog, methylcobalamin, against glutamate cytotoxicity in cultured cortical neurons. Eur J Pharmacol. 1993 Sep 7;241(1):1-6. doi:10.1016/0014-2999(93)90925-8; Wacker J, Frühauf J, Schulz M, et al. Riboflavin deficiency and preeclampsia. Obstet Gynecol. 2000 Jul;96(1):38-44. doi:10.1016/s0029-7844(00)00847-4; Alcazar-Leyva S, Alvarado-Vasquez N. Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients? Med Hypotheses. 2011 May;76(5):629-31. doi:10.1016/j.mehy.2011.01.015. Epub 2011 Feb 1.; McCarty MF, DiNicolantonio JJ. Neuroprotective potential of high-dose biotin. Med Hypotheses. 2017 Nov;109:145-9. doi:10.1016/j.mehy.2017.10.012. Epub 2017 Oct 16.; Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitricoxide synthase. J Biol Chem. 2003 Jun 20;278(25):22546-54. doi:10.1074/jbc.M302227200. Epub 2003 Apr 10.; Frei B. On the role of vitamin C and other antioxidants in atherogenesis and vascular dysfunction. Proc Soc Exp Biol Med. 1999 Dec;222(3):196-204. doi:10.1046/j.1525- 1373.1999.d01-136.x; Mortensen A, Lykkesfeldt J. Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies. Nitric Oxide. 2014 Jan 30;36:51-7. doi:10.1016/j.niox.2013.12.001. Epub 2013 Dec 9.; Saremi A, Arora R. Vitamin E and cardiovascular disease. Am J Ther. 2010 MayJun;17(3):e56-65. doi:10.1097/MJT.0b013e31819cdc9a; Boshtam M, Rafiei M, Sadeghi K, Sarraf-Zadegan N. Vitamin E can reduce blood pressure in mild hypertensives. Int J Vitam Nutr Res. 2002 Oct;72(5):309-14. doi:10.1024/0300- 9831.72.5.309; De la Guia-Galipienso F, Martinez-Ferran M, Vallecillo N, et al. Vitamin D and cardiovascular health. Clin Nutr. 2021 May;40(5):2946-57. doi:10.1016/j.clnu.2020.12.025. Epub 2020 Dec 29.; Kim DH, Meza CA, Clarke H, et al. Vitamin D and Endothelial Function. Nutrients. 2020 Feb 22;12(2):575. doi:10.3390/nu12020575 50. Shi J, Caldwell J, Sheck L, et al. Optic neuropathy from hypovitaminosis A in a series of children with severe dietary restrictions. J Paediatr Child Health. 2024 Oct;60(10):516- 25. doi:10.1111/jpc.16624. Epub 2024 Jul 25.; Lanska DJ. Chapter 29: historical aspects of the major neurological vitamin deficiency disorders: overview and fat-soluble vitamin A. Handb Clin Neurol. 2010;95:435-44. doi:10.1016/S0072-9752(08)02129-5; Wiedermann U, Chen XJ, EnerbКck L, et al. Vitamin A deficiency increases inflammatory responses. Scand J Immunol. 1996 Dec;44(6):578-84. doi:10.1046/j.1365- 3083.1996.d01-351.x; Gadhia MM, Cutter GR, Abman SH, Kinsella JP. Effects of early inhaled nitric oxide therapy and vitamin A supplementation on the risk for bronchopulmonary dysplasia in premature newborns with respiratory failure. J Pediatr. 2014 Apr;164(4):744-8. doi:10.1016/j.jpeds.2013.11.040. Epub 2013 Dec 31.; Чучалин АГ, Шогенова ЛВ, Селемир ВД и др. Способ лечения гиперкапнической дыхательной недостаточности с признаками вторичной легочной артериальной гипертензии. Патент РФ RU2806575C1, Заявка 2023104384 от 27.02.2023.; Nitric Oxide Test Strips. Available at: https://berkeleylife.com/products/nitric-oxidetest-strips/ (accessed 11.09.2024).; Available at: https://aliexpress.ru/item/1005005968674251.html?utm_referrer=https://www.google.com/&sku_id=12000035098155275 (accessed 11.09.2024).; Banjanin N, Belojevic G. Relationship of dietary magnesium intake and serum magnesium with hypertension: a review. Magnes Res. 2021 Nov 1;34(4):166-71. doi:10.1684/mrh.2021.0492; Ye M, Li Q, Xiao L, Zheng Z. Serum Magnesium and Fractional Exhaled Nitric Oxide in Relation to the Severity in AsthmaChronic Obstructive Pulmonary Disease Overlap. Biol Trace Elem Res. 2021 May;199(5):1771-7. doi:10.1007/s12011-020-02314-5. Epub 2020 Sep 18.; Lopez-Jaramillo P. Calcium, nitric oxide, and preeclampsia. Semin Perinatol. 2000 Feb;24(1):33-6. doi:10.1016/s0146-0005(00)80052-x; Vanhatalo A, Blackwell JR, L'Heureux JE, et al. Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans. Free Radic Biol Med. 2018 Aug 20;124:21-30. doi:10.1016/j.freeradbiomed.2018.05.078. Epub 2018 May 25.; Zhou L, Ding C, Wu J, et al. Probiotics and synbiotics show clinical efficacy in treating gestational diabetes mellitus: A meta-analysis. Prim Care Diabetes. 2021 Dec;15(6):937-47. doi:10.1016/j.pcd.2021.08.005. Epub 2021 Aug 18.; Fujisawa H, Watanabe T, Komine O, et al. Prolonged extracellular low sodium concentrations and subsequent their rapid correction modulate nitric oxide production dependent on NFAT5 in microglia. Free Radic Biol Med. 2024 Oct;223:458-72. doi:10.1016/j.freeradbiomed.2024.08.019. Epub 2024 Aug 21.; Fuse S, Fujisawa H, Murao N, et al. Effects of hypernatremia on the microglia. Peptides. 2024 Sep;179:171267. doi:10.1016/j.peptides.2024.171267. Epub 2024 Jun 20.; Wang L, Lu D, Wang X, et al. The effects of nitric oxide in Alzheimer's disease. Med Gas Res. 2024 Dec 1;14(4):186-91. doi:10.4103/2045-9912.385939. Epub 2023 Sep 17.

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    Academic Journal

    المصدر: Medical Herald of the South of Russia; Том 15, № 3 (2024); 33-41 ; Медицинский вестник Юга России; Том 15, № 3 (2024); 33-41 ; 2618-7876 ; 2219-8075 ; 10.21886/2219-8075-2024-15-3

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    Relation: https://www.medicalherald.ru/jour/article/view/1855/1045; https://www.medicalherald.ru/jour/article/downloadSuppFile/1855/863; Абдрахманова А.И., Зарипова Ф.А., Амиров Н.Б. Расстройства тревожно-депрессивного спектра при ревматических заболеваниях. Вестник современной клинической медицины. 2020;13(1):61-65. https://doi.org/10.20969/VSKM.2020.13(1).61-65; Лисицына Т.А., Вельтищев Д.Ю., Серавина О.Ф., Ковалевская О.Б., Старовойтова М.Н., и др. Сравнительный анализ расстройств тревожно-депрессивного спектра у больных ревматическими заболеваниями. Терапевтический архив. 2018;90(5):30-37. https://doi.org/10.26442/terarkh201890530-37; Rohleder N. Acute and chronic stress induced changes in sensitivity of peripheral inflammatory pathways to the signals of multiple stress systems --2011 Curt Richter Award Winner. Psychoneuroendocrinology. 2012;37(3):307-316. https://doi.org/10.1016/j.psyneuen.2011.12.015; Борисова А.Б., Лисицына Т.А., Вельтищев Д.Ю., Решетняк Т.М. Психические расстройства у больных системной красной волчанкой: ассоциация с активностью и течением ревматического заболевания. Терапевтический архив. 2023;95(5):392-397. https://doi.org/10.26442/00403660.2023.05.202208; Beurel E, Toups M, Nemeroff CB. The Bidirectional Relationship of Depression and Inflammation: Double Trouble. Neuron. 2020;107(2):234-256. https://doi.org/10.1016/j.neuron.2020.06.002; Park JS, Jang HD, Hong JY, Park YS, Han K, et al. Impact of ankylosing spondylitis on depression: a nationwide cohort study. Sci Rep. 2019;9(1):6736. https://doi.org/10.1038/s41598-019-43155-0; Zhang L, Wu Y, Liu S, Zhu W. Prevalence of Depression in Ankylosing Spondylitis: A Systematic Review and MetaAnalysis. Psychiatry Investig. 2019;16(8):565-574. https://doi.org/10.30773/pi.2019.06.05; Антипова О.С. Проблемы и перспективы изучения вегетативной регуляции при депрессиях. Доктор.Ру. 2019;161(6):42-46. https://doi.org/10.31550/1727-2378-2019-161-6-42-46; Николаев А.Б., Джебраилова Т.Д. Взаимосвязь между тревожностью и вариабельностью сердечного ритма при коррекции психоэмоционального напряжения. Российский физиологический журнал им. И. М. Сеченова. 2018;104(8):984-995 https://doi.org/10.7868/S0869813918070092; Антипова О.С., Краснов В.Н., Трофимова О.С. Изменения вегетативной регуляции при депрессивных расстройствах умеренной тяжести. Журнал неврологии и психиатрии имени С.С. Корсакова. 2013;11(2):65-73. eLIBRARY ID: 21074391 EDN: RTELIZ; Лазарева Н.В., Белянин В.В. Оценка вегетативной регуляции деятельности сердца у больных системной склеродермией. Современная наука: актуальные проблемы теории и практики. Серия: Естественные и технические науки. 2018;5:154-156. eLIBRARY ID: 35417229 EDN: XWASUX; Kim HG, Cheon EJ, Bai DS, Lee YH, Koo BH. Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature. Psychiatry Investig. 2018;15(3):235-245. https://doi.org/10.30773/pi.2017.08.17; Behbahani S, Shahram F. Electrocardiogram and heart rate variability assessment in patients with common autoimmune diseases: a methodological review. Turk Kardiyol Dern Ars. 2020;48(3):312-327. https://doi.org/10.5543/tkda.2019.21112; Ben Mrad I, Ben Mrad M, Besbes B, Zairi I, Ben Kahla N, et al. Heart Rate Variability as an Indicator of Autonomic Nervous System Disturbance in Behcet's Disease. Int J Gen Med. 2021;14:4877-4886. https://doi.org/10.2147/IJGM.S326549; Sessa F, Anna V, Messina G, Cibelli G, Monda V, et al. Heart rate variability as predictive factor for sudden cardiac death. Aging (Albany NY). 2018;10(2):166-177. https://doi.org/10.18632/aging.101386; Новикова Д.С., Попкова Т.В., Герасимова Е.В., Новиков А.А., Александрова Е.Н., Насонов Е.Л. Динамика частоты сердечных сокращений, показателей вариабельности ритма сердца и величины интервала Q–T у женщин с ревматоидным артритом на фоне лечения ритуксимабом. Научно-практическая ревматология. 2014;52(3):270-276. https://doi.org/10.14412/1995-4484-2014-270-276; Удачкина Е.В., Новикова Д.С., Попкова Т.В., Насонов Е.Л. Значение вариабельности ритма сердца при ревматоидном артрите. Научно-практическая ревматология. 2015;53(6):646-652. https://doi.org/10.14412/1995-4484-2015-646-652; Adlan AM, Veldhuijzen van Zanten JJCS, Lip GYH, Paton JFR, Kitas GD, Fisher JP. Cardiovascular autonomic regulation, inflammation and pain in rheumatoid arthritis. Auton Neurosci. 2017;208:137-145. https://doi.org/10.1016/j.autneu.2017.09.003; Филимонова О.Г., Симонова О.В., Чупраков П.Г. Психоэмоциональные нарушения и особенности вегетативной регуляции у больных ревматическими заболеваниями. Вятский медицинский вестник. 2010;3:51-57. eLIBRARY ID: 16860378 EDN: OEYVWT; Borman P, Gokoglu F, Kocaoglu S, Yorgancioglu ZR. The autonomic dysfunction in patients with ankylosing spondylitis: a clinical and electrophysiological study. Clin Rheumatol. 2008;27(10):1267-1273. https://doi.org/10.1007/s10067-008-0906-0; Law L, Beckman Rehnman J, Deminger A, Klingberg E, Jacobsson LTH, Forsblad-d'Elia H. Factors related to healthrelated quality of life in ankylosing spondylitis, overall and stratified by sex. Arthritis Res Ther. 2018;20(1):284. https://doi.org/10.1186/s13075-018-1784-8; Раскина ТА, Пирогова ОА, Пивоварова ЖА. Влияние инфликсимаба на качество жизни пациентов с анкилозирующим спондилитом по данным опросника SF-36. Современная ревматология. 2013;7(3):47-50. https://doi.org/10.14412/1996-7012-2013-13; Peláez-Ballestas I, Boonen A, Vázquez-Mellado J, Reyes-Lagunes I, Hernández-Garduño A, et al. Coping strategies for health and daily-life stressors in patients with rheumatoid arthritis, ankylosing spondylitis, and gout: STROBE-compliant article. Medicine (Baltimore). 2015;94(10):e600. https://doi.org/10.1097/MD.0000000000000600; Балабанова РМ, Ильиных ЕВ, Подряднова МВ, Глухова СИ, Урумова ММ. Значение бессимптомной гиперурикемии при анкилозирующем спондилите. Современная ревматология. 2021;15(3):57-61. https://doi.org/10.14412/1996-7012-2021-3-57-61; https://www.medicalherald.ru/jour/article/view/1855

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    Academic Journal

    المصدر: Eurasian Journal of Medical and Natural Sciences; Vol. 4 No. 10 (2024): Евразийский журнал медицинских и естественных наук; 49-53 ; Евразийский журнал медицинских и естественных наук; Том 4 № 10 (2024): Евразийский журнал медицинских и естественных наук; 49-53 ; Yevrosiyo tibbiyot va tabiiy fanlar jurnali; Jild 4 Nomeri 10 (2024): Евразийский журнал медицинских и естественных наук; 49-53 ; 2181-287X

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    Academic Journal
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    المصدر: Сборник статей

    وصف الملف: application/pdf

    Relation: Актуальные вопросы современной медицинской науки и здравоохранения : Сборник статей IX Международной научно-практической конференции молодых ученых и студентов, 17-18 апреля 2024 г. Т. 1.; Огаркова, Е. И. Биоэнергетика как альтернативное терапевтическое направление / Е. И. Огаркова, Е. В. Власова. - Текст: электронный // Актуальные вопросы современной медицинской науки и здравоохранения : Сборник статей IX Международной научно-практической конференции молодых ученых и студентов, 17-18 апреля 2024 г. Т. 1. - Екатеринбург, 2024. – C. 682-687.; http://elib.usma.ru/handle/usma/21316

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    Academic Journal

    المساهمون: The work was carried out with the financial support of the Russian Science Foundation (project No. 20-15-00271 P)., Работа выполнена при финансовой поддержке Российского научного фонда (проект № 20-15-00271П).

    المصدر: Translational Medicine; Том 11, № 2 (2024); 170-180 ; Трансляционная медицина; Том 11, № 2 (2024); 170-180 ; 2410-5155 ; 2311-4495

    وصف الملف: application/pdf

    Relation: https://transmed.almazovcentre.ru/jour/article/view/889/569; https://transmed.almazovcentre.ru/jour/article/downloadSuppFile/889/1986; https://transmed.almazovcentre.ru/jour/article/downloadSuppFile/889/2003; https://transmed.almazovcentre.ru/jour/article/downloadSuppFile/889/2004; Devi S, Kim JJ, Singh AP, et al. Proteotoxicity: A Fatal Consequence of Environmental Pollutants-Induced Impairments in Protein Clearance Machinery. J Pers Med. 2021;11(2):69. DOI:10.3390/jpm11020069.; Schreiber A, Peter M. Substrate recognition in selective autophagy and the ubiquitin-proteasome system. Biochim Biophys Acta. 2014;1843(1):163–81. DOI:10.1016/j.bbamcr.2013.03.019.; Castets P, Frank S, Sinnreich M, Ruegg MA. “Get the Balance Right”: Pathological Significance of Autophagy Perturbation in Neuromuscular Disorders. J Neuromuscul Dis. 2016;3(2):127–55. DOI:10.3233/JND-160153; Bonuccelli G, Sotgia F, Schubert W, et al. Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins. Am J Pathol. 2003;163(4):1663–75. DOI:10.1016/S0002-9440(10)63523-7.; Bodine SC, Baehr LM. Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1. Am J Physiol Endocrinol Metab. 2014;307(6):E469–84. DOI:10.1152/ajpendo.00204.2014.; Tannous P, Zhu H, Johnstone JL, et al. Autophagy is an adaptive response in desmin-related cardiomyopathy. Proc Natl Acad Sci U S A. 2008;105(28):9745–9750. DOI:10.1073/pnas.0706802105.; Carmignac V, Svensson M, Korner Z, et al. Autophagy is increased in laminin alpha2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A. Hum Mol Genet. 2011;20(24):4891–902. DOI:10.1093/hmg/ddr427.; Gawlik KI, Durbeej M. Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies. Skelet Muscle. 2011;1(1):9. 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DOI:10.1016/j.yjmcc.2013.12.015.; Verdonschot JAJ, Vanhoutte EK, Claes GRF, et al. A mutation update for the FLNC gene in myopathies and cardiomyopathies. Hum Mutat. 2020;41(6):1091–1111. DOI:10.1002/humu.24004.; Cassandrini D, Merlini L, Pilla F, et al. Protein aggregates and autophagy involvement in a family with a mutation in Z-band alternatively spliced PDZ-motif protein. Neuromuscul Disord. 2021;31(1):44–51. DOI:10.1016/j.nmd.2020.11.008.; Bhuiyan MS, Pattison JS, Osinska H, et al. Enhanced autophagy ameliorates cardiac proteinopathy. J Clin Invest. 2013;123(12):5284–97. DOI:10.1172/JCI70877.; Pattison JS, Osinska H, Robbins J. Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes. Circ Res. 2011;109(2):151– 60. DOI:10.1161/CIRCRESAHA.110.237339; Song L, Su M, Wang S, et al. MiR-451 is decreased in hypertrophic cardiomyopathy and regulates autophagy by targeting TSC1. J Cell Mol Med. 2014;18(11):2266–2274. DOI:10.1111/jcmm.12380.; Singh SR, Zech ATL, Geertz B, et al. Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice. Circ Heart Fail. 2017;10(10). DOI:10.1161/CIRCHEARTFAILURE.117.004140.; Iskratsch T, Lange S, Dwyer J, et al. Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance. Journal of Cell Biology. 2010;191(6):1159–72. DOI:10.1083/jcb.201005060.; Ruparelia AA, Oorschot V, Ramm G, Bryson-Richardson RJ. FLNC myofibrillar myopathy results from impaired autophagy and protein insufficiency. Hum Mol Genet. 2016;25(11):2131–2142. DOI:10.1093/hmg/ddw080.; McNamara JW, Parker BL, Voges HK, et al. Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle. Nature Cardiovascular Research. 2023;2(2):159–173. DOI: https://doi.org/10.1038/s44161-023-00219-9.; Kumar V, Kumar P, Chauhan L, et al. Novel combination of FLNC (c.5707G>A; p. Glu1903Lys) and BAG3 (c.610G>A; p.Gly204Arg) genetic variant expressing restrictive cardiomyopathy phenotype in an adolescent girl. J Genet. 2022;101:54.; Teixeira CA, Almeida Mdo R, Saraiva MJ. Impairment of autophagy by TTR V30M aggregates: in vivo reversal by TUDCA and curcumin. Clin Sci (Lond). 2016;130(18):1665–75. DOI:10.1042/CS20160075.; Yanagisawa H, Hossain MA, Miyajima T, et al. Dysregulated DNA methylation of GLA gene was associated with dysfunction of autophagy. Mol Genet Metab. 2019;126(4):460–465. DOI:10.1016/j.ymgme.2019.03.003.; https://transmed.almazovcentre.ru/jour/article/view/889

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    المساهمون: The work was carried out within the using the infrastructure of the Federal Research Center “Computer Science and Control” of the Russian Academy of Sciences., работа выполнена с использованием инфраструктуры Центра коллективного пользования «Высокопроизводительные вычисления и большие данные» ФИЦ «Информатика и управление» РАН.

    المصدر: Meditsinskiy sovet = Medical Council; № 3 (2024); 70-79 ; Медицинский Совет; № 3 (2024); 70-79 ; 2658-5790 ; 2079-701X

    وصف الملف: application/pdf

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Effects of statins on energy and fatigue with exertion: results from a randomized controlled trial. Arch Intern Med. 2012;172(15):1180–1182. https://doi.org/10.1001/archinternmed.2012.2171.; Громова ОА, Торшин ИЮ. Микронутриенты и репродуктивное здоровье. 2-е изд. М.: ГЭОТАР-Медиа; 2022. 832 c.; Громова ОА, Захарова ИН, Торшин ИЮ, Гришина ТР, Лиманова ОА. О патофизиологической терапии астении у детей препаратами цитруллина малата. Медицинский совет. 2017;(19):142–148. https://doi.org/10.21518/2079-701X-2017-19-142-148.; Jensen A, Glenn J, Stone M, Gray M. Effect Of Acute Citrulline-malate Supplementation On Muscular Power. Med Sci Sports Exerc. 2016;48(5S):252. https://doi.org/10.1249/01.mss.0000485759.38927.5f.; Glenn JM, Gray M, Jensen A, Stone MS, Vincenzo JL. Acute Citrulline-Malate Supplementation Increases Strength and Endurance During Isokinetic Exercise in Masters-Aged Female Tennis Players. 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    المؤلفون: Павлова, О. О.

    Relation: Павлова О. О. Вплив мезенхімальних стовбурових клітин на показники прооксидантно-антиоксидантного гомеостазу у щурів зі скополамін-індукованою деменцією альцгеймерівського типу / О. О. Павлова, Є. М. Лукянова // Матеріали Всеукр. наук.-практ. конф. молодих учених «Медична наука – 2023», (м. Полтава, 1 грудня 2023 р.). – Полтава, 2023. – С. 74–75.; http://repository.pdmu.edu.ua/handle/123456789/22727

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    Relation: Штробля В. В. Універсальні можливості карбоксітерапії в медицині / В. В. Штробля, С. С. Філіп, Р. В. Луценко // Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії. – 2023. – Т. 23, вип. 3 (83). – С. 231–236.; 2077-1096 (print); 2077-1126 (online); http://repository.pdmu.edu.ua/handle/123456789/22215

  20. 20
    Academic Journal

    المصدر: Actual Problems of Pediatrics, Obstetrics and Gynecology; No. 1 (2023); 48-52 ; Актуальные вопросы педиатрии, акушерства и гинекологии; № 1 (2023); 48-52 ; Актуальні питання педіатрії, акушерства та гінекології; № 1 (2023); 48-52 ; 2415-301X ; 2411-4944 ; 10.11603/24116-4944.2023.1

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