المؤلفون: A. Enikeev D., A. Komelkov V., M. Axelrod E., S. Galetsky A., E. Tchevkina M., А. Еникеев Д., А. Комельков В., М. Аксельрод Е., С. Галецкий А., Е. Чевкина М.

المساهمون: The study was performed with the support of the Russian Foundation for Basic Research (project No. 19-015-00027A)., Исследование выполнено при поддержке Российского фонда фундаментальных исследований (проект № 19-015-00027А).

المصدر: Advances in Molecular Oncology; Том 7, № 4 (2020); 46-50 ; Успехи молекулярной онкологии; Том 7, № 4 (2020); 46-50 ; 2413-3787 ; 2313-805X ; 10.17650/2313-805X-2020-7-4

مصطلحات موضوعية: retinoic acid, ATRA, CRABP1, proliferation, breast cancer, ретиноевая кислота, пролиферация, рак молочной железы

وصف الملف: application/pdf

Relation: https://umo.abvpress.ru/jour/article/view/303/218; Schenk T., Stengel S., Zelent A. Unlocking the potential of retinoic acid in anticancer therapy. Br J Cancer 2014;111(11): 2039–45. DOI:10.1038/bjc.2014.412.; Connolly R.M., Nguyen N.K., Sukumar S. Molecular pathways: current role and future directions of the retinoic acid pathway in cancer prevention and treatment. Clin Cancer Res 2013;19(7):1651–959. DOI:10.1158/1078-0432.CCR-12-3175.; Vreeland A.C., Levi L., Zhang W. et al. Cellular retinoic acid-binding protein 2 inhibits tumor growth by two distinct mechanisms. J Biol Chem 2013;289(49):34065–73. DOI:10.1074/jbc.M114.604041.; Dong D., Ruuska S.E., Levinthal D.J., Noy N. Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid. J Biol Chem 1999;274(34):23695–8. DOI:10.1074/jbc.274.34.23695.; Еникеев А.Д., Комельков А.В., Зборовская И.Б. и др. Неканоническая активность ретиноевой кислоты в отношении активации протеинкиназ в трансформированных клетках различного происхождения. Успехи молекулярной онкологии 2018;5(4):127–30.; Tchevkina E.M. Retinoic acid binding proteins and cancer: similarity or polarity? Cancer Ther Oncol Int J 2017;8(2):555733. DOI:10.19080/ctoij.2017.08.555733.; Kainov Y., Favorskaya I., Delektorskaya V. et al. CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors. Cell Cycle 2014;13(10):1530–39. DOI:10.4161/cc.28475.; Еникеев А.Д., Комельков А.В., Аксельрод М.Е. и др. Влияние экспрессии CRABP1 на рост и чувствительность к ретиноевой кислоте клеток РМЖ различного происхождения. Биохимия 2020. В печати.; Favorskaya I., Kainov Y., Chemeris G. et al. Expression and clinical significance of CRABP1 and CRABP2 in non-small cell lung cancer. Tumor Biol 2014;35(10): 10295–300. DOI:10.1007/s13277-014-2348-4.; Liu R.Z., Garcia E., Glubrecht D.D. et al. CRABP1 is associated with a poor prognosis in breast cancer: adding to the complexity of breast cancer cell response to retinoic acid. Mol Cancer 2015;14(1):129. DOI:10.1186/s12943-015-0380-7.; https://umo.abvpress.ru/jour/article/view/303

الاتاحة: https://umo.abvpress.ru/jour/article/view/303
https://doi.org/10.17650/2313-805X-2020-7-4-46-50

المؤلفون: A. Enikeev D., A. Komelkov V., I. Zborovskaya B., S. Galetsky A., G. Skryabin O., E. Tchevkina M., А. Еникеев Д., А. Комельков В., И. Зборовская Б., С. Галецкий А., Г. Скрябин О., Е. Чевкина М.

المساهمون: Russian Foundation for Basic Research, No. 16-04-01 559А, Российский фонд фундаментальных исследований, № 16-04-01 559А

المصدر: Advances in Molecular Oncology; Том 5, № 4 (2018); 127-130 ; Успехи молекулярной онкологии; Том 5, № 4 (2018); 127-130 ; 2413-3787 ; 2313-805X ; 10.17650/2313-805X-2018-5-4

مصطلحات موضوعية: retinoic acid, non-canonical activity, protein kinase, phosphorylation, Erk1/2, Akt, ретиноевая кислота, неканоническая активность, протеинкиназа, фосфорилирование

وصف الملف: application/pdf

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الاتاحة: https://umo.abvpress.ru/jour/article/view/182
https://doi.org/10.17650/2313-805X-2018-5-4-127-130