يعرض 1 - 5 نتائج من 5 نتيجة بحث عن '"О. Никитина В."', وقت الاستعلام: 0.41s تنقيح النتائج
  1. 1
    Academic Journal

    المصدر: Russian Sklifosovsky Journal "Emergency Medical Care"; Том 9, № 2 (2020); 201-209 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 9, № 2 (2020); 201-209 ; 2541-8017 ; 2223-9022 ; 10.23934/2223-9022-2020-9-2

    وصف الملف: application/pdf

    Relation: https://www.jnmp.ru/jour/article/view/929/766; https://www.jnmp.ru/jour/article/view/929/856; Rhee С, Dantes R, Epstein L, Murphy DJ, Seymour CW, Iwashyna TJ, et al. Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014. JAMA. 2017;318(13):1241–1249. PMID: 28903154 https://doi.org/10.1001/jama.2017.13836; Vincent JL, Lefrant JY, Kotfis K, Nanchal R, Martin-Loeches I, Wittebole X, et al. Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP). Intensive Care Med. 2018;44(3):337–344. PMID: 29450593 https://doi.org/10.1007/s00134-017-5043-2; Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801–810. PMID: 26903338 https://doi.org/10.1001/jama.2016.0287; Chen XH, Yin YJ, Zhang JX. Sepsis and immune response. World J Emerg Med. 2011;2(2):88–92. PMID: 25214990; Lewis DH, Chan DL, Pinheiro D, Armitage-Chan E, Garden OA. The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory anti-inflammatory response, and regulatory T cells. J Vet Intern Med. 2012;26:457–482. PMID: 22428780 https://doi.org/10.1111/j.1939-1676.2012.00905.x; Яковлев М.Ю. Кишечный липополисахарид: системная эндотоксинемия – эндотоксиновая агрессия – SIRS-полиорганная недостаточность как звенья одной цепи. Бюллетень ВНЦ СО РАМН. 2005;(1):15–18.; Triantafilou M, Triantafilou K. Sepsis: molecular mechanisms underlying lipopolysaccharide recognition. Expert Rev Mol Med. 2004;6(4):1–18. PMID: 14987416 https://doi.org/10.1017/S1462399404007409; Marshall JC, Foster D, Vincent JL, Cook DJ, Cohen J, Dellinger RP, et al. Diagnostic and Prognostic Implications of Endotoxemia in Critical Illness: Results of the MEDIC Study. J Infect Dis. 2004;190(3):527–534. PMID: 15243928 https://doi.org/10.1086/422254; Reade MC, Huang DT, Bell D, Coats TJ, Cross AM, Moran JL, et al. Variability in management of early severe sepsis. Emerg. Med. J. 2010;27(2):110–115. PMID: 20156862 https://doi.org/10.1136/emj.2008.070912; Solomkin JS, Bauman MR, Neeson RD, Simmons RL. Neutrophils dysfunction during the course of intra-abdominal infection. Ann Surg. 1981;194(1):9–17. PMID: 7247540 https://doi.org/10.1097/00000658-198107000-00003; Triantafilou M, Triantafilou K. Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol. 2002;23(6):301– 304. PMID: 12072369; Cruz DN, Perazella MA, Dellomo R, de Cal M, Polanco N, Corradi V, еt al. Effectivnes of polymyxin B-immobilized fiber column in sepsis: a systematic review. Crit Care. 2007;11(2);R 47 PMID: 17448226 https://doi.org/10.1186/cc5780; Ikeda T, Ikeda K, Nagura M, Taniuchi H, Matsushita M, Kiuchi S, et al. Clinical evaluation of PMX-DHP for hypercytokinemia caused by septic multiple organ failure. Ther Apher Dial. 2004;8(4):293–298. PMID: 15274680 https://doi.org/10.1111/j.1526-0968.2004.00167.x; Cruz DN, Antonelli M, Fumagalli R, Foltran F, Brienza N, Donati A, et al. Early use of polymyxin B hemoperfusion in abdominal septic shock: the EUPHAS randomized controlled trial. JAMA. 2009;301(23):2445–2452. PMID: 19531784 https://doi.org/10.1001/jama.2009.856; Payen DM, Guilhot J, Launey Y, Lukaszewicz AC, Kaaki M, Veber B, et al. Early use of polymyxin B hemoperfusion in patients with septic shock due to peritonitis: a multicenter randomized control trial. Intensive Care Med. 2015;41(6):975–984. PMID: 25862039 https://doi.org/10.1007/s00134-015-3751-z; Cutuli SL, Artigas A, Fumagalli R, Monti G, Ranieri VM, Ronco C, et al. EUPHAS 2 Collaborative Group. Polymyxin-B hemoperfusion in septic patients: analysis of a multicenter registry. Ann Intensive Care. 2016;6(1):77. PMID: 27502196 https://doi.org/10.1186/s13613-016-0178-9; Dellinger RP, Bagshaw SM, Antonelli M, Foster DM, Klein DJ, Marshall JC, et al. EUPHRATES Trial Investigators. Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level: The EUPHRATES Randomized Clinical Trial. JAMA. 2018;320(14):1455–1463. PMID: 30304428 https://doi.org/10.1001/jama.2018.14618; Klein DJ, Foster D, Walker PM, Bagshaw SM, Mekonnen H, Antonelli M. Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial. Intensive Care Med. 2018;44(12):2205–2212. PMID: 30470853 https://doi.org/10.1007/s00134-018-5463-7; Adamik B, Zielinski S, Smiechowicz J, Kübler A. Endotoxin Elimination in Patients with Septic Shock: An Observation Study. Arch Immunol Ther Exp (Warsz). 2015;63(6):475–483. PMID: 26093653 https://doi.org/10.1007/s00005-015-0348-8; Zagli G, Bonizzoli M, Spina R, Cianchi G, Pasquini A, Anichini V, et al. Effects of hemoperfusion with an immobilized polymixin-B fibers column on cytokine plasma levels in patients with abdominal sepsis.; Nakamura T, Ebihara I, Shimada N, Koide H. Changes in plasma erythropoietin and interkeukin-6 concentranions in patients with septic shock after hemoperfusion with polymixin B- immobilized fibers. Intensive Care Med. 1998;24(12):1272–1276. PMID: 9885879; Крстич М., Зулькарнаев А.Б. Селективная адсорбция эндотоксина в лечении гнойно-септических осложнений у пациентов с урологическими заболеваниями после трансплантации почки. Вестник трансплантологии и искусственных органов. 2014;16(1):21–28.; Yaroustovsky M, Plyushch M, Popov D, Samsonova N, Abramyan M, Popok Z, et al. Prognostic value of endotoxin activity assay in patients with severe sepsis after cardiac surgery. J Inflamm (Lond). 2013;10(1):8. PMID: 23510603 https://doi.org/10.1186/1476-9255-10-8; Nakamura T, Sato E, Fujiwara N, Kawagoe Y, Maeda S, Yamagishi S. Suppression of high-mobility group box-1 and receptor for advanced glycation end-product axis by polymyxin B-immobilized fiber hemoperfusion in septic shock patients. J Crit Care. 2011;26(6):546–549. PMID: 21273029 https://doi.org/10.1016/j.jcrc.2010.11.010; Coudroy R, Payen D, Launey Y, Lukaszewicz AC, Kaaki M, Veber B, et al. Modulation by Polymyxin-B Hemoperfusion of Inflammatory Response Related to Severe Peritonitis. Shock. 2017;47(1):93-99. PMID: 27984535 https://doi.org/10.1097/SHK.0000000000000725; https://www.jnmp.ru/jour/article/view/929

  2. 2
    Academic Journal

    المصدر: Russian Sklifosovsky Journal "Emergency Medical Care"; Том 7, № 2 (2018); 134-143 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 7, № 2 (2018); 134-143 ; 2541-8017 ; 2223-9022 ; 10.23934/2223-9022-2018-7-2

    وصف الملف: application/pdf

    Relation: https://www.jnmp.ru/jour/article/view/464/535; https://www.jnmp.ru/jour/article/view/464/536; Dong B., Pineo G., Mulrooney T. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2002; (3): CD004437. DOI:10.1002/14651858.CD004437; Dong B.R., Yue J., Liu G.J., et al. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2006; (2): CD004437. PMID: 16625603. DOI:10.1002/14651858.CD004437.pub2.; Dong B.R., Hao Q., Yue J., et al. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2009; (3): CD004437. PMID: 19588357. DOI:10.1002/14651858.CD004437.pub3.; Hao Q., Dong B.R., Yue J., et al. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2015; (9): CD004437. PMID: 26419832. DOI:10.1002/14651858.CD004437.pub4.; Meyer G., Vicaut E., Danays T., et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N. Engl. J. Med. 2014; 370(15): 1402–1411. PMID: 24716681. DOI:10.1056/NEJMoa1302097.; Cook G.J.R. Clinical Nuclear Medicine. London; New York, 2006. 915 p.; Konstantinides S.V., Torbicki A., Agnelli G., et al. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism. Eur. Heart J. 2014; 35(43): 3033-3069, 3069a-3069k. PMID: 25173341. DOI:10.1093/eurheartj/ehu283.; Torbicki A., Perrier A., Konstantinides S., et al. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur. Heart J. 2008; 29(18): 2276–2315. PMID: 18757870. DOI:10.1093/eurheartj/ehn310.; Pistolesi M., Lavorini F., Miniati M. Diagnostic strategies for suspected pulmonary embolism. European respiratory monograph. 2004. Monograph 30. Ch.6: Imaging: 89–105.; Van Beek E., Moody A.R., Oudkerk M. Imaging of pulmonary embolism: an overview. In: European respiratory monograph. 2003. Monograph 27. Ch.7: Pulmonary Vascular Pathology: A Clinical Update: 110–123.; Bajc M., Olsson B., Palmer J., et al. Ventilation / Perfusion SPECT for diagnostics of pulmonary embolism in clinical practice. J. Intern. Med. 2008; 264(4): 379–387. PMID: 18823506. DOI:10.1111/j.1365- 2796.2008.01980.x.; Collart J.P., Roelants V., Vanpee D., et al. Is a Lung perfusion scan obtained by using single photon emission computed tomography able to improve the radionuclide diagnosis of pulmonary embolism? Nucl. Med. Commun. 2002; 23(11): 1107–1113. PMID: 12411840. DOI:10.1097/01.mnm.0000040972.43128.16.; Corbus H.F., Seitz J.P., Larson R.K., et al. Diagnostic usefulness of lung SPECT in pulmonary thromboembolism: an outcome study. Nucl. Med. Commun. 1997; 18 (10): 897–906. PMID: 9392789.; Reinartz P., Wildberger J.E., Schaefer W., et al. Tomographic imaging in the diagnosis of pulmonary embolism: a comparison between V/Q lung scintigraphy in SPECT technique and multislice spiral CT. J. Nucl. Med. 2004; 45(9): 1501–1508. PMID: 15347717.; Gutte H., Mortensen J., Jensen C.V., et al. Detection of pulmonary embolism with combined ventilation-perfusion SPECT and low-dose CT: head-to-head comparison with multidetector CT angiography. J. Nucl. Med. 2009; 50(12): 1987–1992. PMID: 19910421. DOI:10.2967/ jnumed.108.061606.; Савельев В.С., Яблоков Е.Г., Кириенко А.И. Массивная эмболия легочной артерии. М.: Медицина, 1990. 336 c.; Бокарев И.Н., Попова Л.В. Венозный тромбоэмболизм и тромбоэмболия легочной артерии. М.: МИА, 2005. 208 с.; https://www.jnmp.ru/jour/article/view/464

  3. 3
    Academic Journal

    المصدر: Russian Sklifosovsky Journal "Emergency Medical Care"; Том 7, № 3 (2018); 209-216 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 7, № 3 (2018); 209-216 ; 2541-8017 ; 2223-9022 ; 10.23934/2223-9022-2018-7-3

    وصف الملف: application/pdf

    Relation: https://www.jnmp.ru/jour/article/view/501/562; https://www.jnmp.ru/jour/article/view/501/563; Савельев В.С., Чазов Е.И., Гусев Е.И., Кириенко А.И. Российские клинические рекомендации по диагностике, лечению и профилактике венозных тромбоэмболических осложнений. Флебология. 2010; (4, Вып. 2): 3–37.; Konstantinides S.V., Torbicki A., Agnelli G. et al. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism. Eur. Heart J. 2014; 35(43): 3033–3069, 3069a–3069k. PMID: 25173341. DOI:10.1093/eurheartj/ehu283.; Kearon C., Kahn S.R., Agnelli G., et al. American College of Chest Physicians. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008; 133(6, Suppl.): 454S–545S. PMID: 18574272. DOI:10.1378/chest.08-0658.; Jaff M.R., McMurtry M.S., Archer S.L., et al. Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension A Scientific Statement From the American Heart Association. Circulation. 2011; 123(16): 1788–1830. PMID: 21422387. DOI:10.1161/CIR.0b013e318214914f.; British Thoracic Society Standards of Care Committee Pulmonary Embolism Guideline Development Group. British Thoracic Society guidelines for the management of suspected acute pulmonary embolism. Thorax. 2003; 58(6): 470–484. PMID: 12775856.; Stein P.D., Matta F. Thrombolytic therapy in unstable patients with acute pulmonary embolism: saves lives but underused. Am. J. Med. 2012; 125(5): 465–470. PMID: 22325236. DOI:10.1016/j.amjmed.2011.10.015.; Meyer G., Vicaut E., Danays T., et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N. Engl. J. Med. 2014; 370(15): 1402–1411. PMID: 24716681. DOI:10.1056/NEJMoa1302097.; Konstantinides S.V., Barco S. Systemic Thrombolytic Therapy for Acute Pulmonary Embolism: Who Is a Candidate? Semin Respir Crit Care Med. 2017; 38(1): 56–65. PMID: 28208199. DOI:10.1055/s-0036-1597560.; Felgendreher R., Härtel D., Brockmeier J. et al. Acute pulmonary embolism: still a diagnostic and therapeutic challenge? Med Klin Intensivmed Notfmed. 2017; 112(6): 499–509. PMID: 27807613. DOI:10.1007/s00063-016-0221-5.; Konstantinides S.V., Barco S., Lankeit M., Meyer G. Management of Pulmonary Embolism: An Update. J Am Coll Cardiol. 2016; 67(8): 976–990. PMID: 26916489. DOI:10.1016/j.jacc.2015.11.061.; Marti C., John G., Konstantinides S. et al. Systemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis. Eur Heart J. 2015; 36(10): 605–614. PMID: 24917641. DOI:10.1093/eurheartj/ehu218.; Meyer G., Planquette B., Sanchez O. Fibrinolysis for Acute Care of Pulmonary Embolism in the Intermediate Risk Patient. Curr Atheroscler Rep. 2015; 17(12): 68. PMID: 26486512. DOI:10.1007/s11883-0150546-1.; Marshall P.S., Tapson V., Jiménez D. Controversies in the Management of Life-Threatening Pulmonary Embolism. Semin Respir Crit Care Med. 2015; 36(6): 835–841. PMID: 26595043. DOI:10.1055/s-0035-1564733.; Sanchez O., Planquette B., Meyer G. Management of massive and submassive pulmonary embolism: focus on recent randomized trials. Curr Opin Pulm Med. 2014; 20(5): 393–399. PMID: 25029299. DOI:10.1097/MCP.0000000000000089.; Sharifi M., Bay C., Skrocki L. et al. Moderate pulmonary embolism treated with thrombolysis (from the “MOPETT” Trial). Am J Cardiol. 2013; 111(2): 273–277. PMID: 2310288. DOI:10.1016/j.amjcard.2012.09.027.; Hao Q., Dong B.R., Yue J. et al. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2015; (9): CD004437. PMID: 26419832. DOI:10.1002/14651858.CD004437.pub4.; Савельев В.С., Яблоков Е.Г., Кириенко А.И. Массивная эмболия легочной артерии. М.: Медицина, 1990. 336 с.; Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale, New Jersey: Lawrence Erlbaum Associates, Publishers, 1988. 567 p.; https://www.jnmp.ru/jour/article/view/501

  4. 4
    Academic Journal

    المصدر: Russian Sklifosovsky Journal "Emergency Medical Care"; Том 7, № 1 (2018); 20-29 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 7, № 1 (2018); 20-29 ; 2541-8017 ; 2223-9022 ; 10.23934/2223-9022-2018-7-1

    وصف الملف: application/pdf

    Relation: https://www.jnmp.ru/jour/article/view/433/496; https://www.jnmp.ru/jour/article/view/433/497; Савельев В.С., Чазов Е.И., Гусев Е.И., Кириенко А.И. Российские клинические рекомендации по диагностике, лечению и профилактике венозных тромбоэмболических осложнений. Флебология. 2010; 44(2–1): 3–37.; Konstantinides S.V., Torbicki A., Agnelli G., et al. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism. Eur. Heart J. 2014; 35(43): 3033–3069, 3069a–3069k. PMID: 25173341. DOI:10.1093/eurheartj/ehu283.; Kearon C., Kahn S.R., Agnelli G., et al. American College of Chest Physicians. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008; 133(6 Suppl): 454S–545S. PMID: 18574272. DOI:10.1378/chest.08-0658.; Jaff M.R., McMurtry M.S., Archer S.L., et al. Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension A Scientific Statement From the American Heart Association. Circulation. 2011; 123(16): 1788–1830. PMID: 21422387. DOI:10.1161/ CIR.0b013e318214914f.; British Thoracic Society Standards of Care Committee Pulmonary Embolism Guideline Development Group. British Thoracic Society guidelines for the management of suspected acute pulmonary embolism. Thorax 2003; 58(6): 470–484. PMID: 12775856.; Torbicki A., Perrier A., Konstantinides S., et al. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J. 2008; 29(18): 2276–2315. PMID: 18757870. DOI:10.1093/eurheartj/ehn310.; Dong B., Pineo G., Mulrooney T. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2002; (3). DOI:10.1002/14651858.CD004437.; Dong B.R., Yue J., Liu G.J., et al. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2006 Apr 19; (2): CD004437. PMID: 16625603. DOI:10.1002/14651858.CD004437.pub2.; Dong B.R., Hao Q., Yue J., et al. Thrombolytic therapy for pulmonary embolism. . Cochrane Database Syst. Rev. 2009 Jul 8; (3): CD004437. PMID: 19588357. DOI:10.1002/14651858.CD004437.pub3.; Hao Q., Dong B.R., Yue J., et al. Thrombolytic therapy for pulmonary embolism. Cochrane Database Syst. Rev. 2015 Sep 30; (9): CD004437. PMID: 26419832. DOI:10.1002/14651858.CD004437.pub4.; Meyer G., Vicaut E., Danays T., et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N. Engl. J. Med. 2014; 370(15): 1402–1411. PMID: 24716681. DOI:10.1056/NEJMoa1302097.; Chatterjee S., Chakraborty A., Weinberg I., et al. Thrombolysis for pulmonary embolism and risk of all-cause mortality, major bleeding, and intracranial hemorrhage: a meta-analysis. JAMA. 2014; 311(23): 2414–2421. PMID: 24938564. DOI:10.1001/jama.2014.5990.; Stein P.D., Matta F. Thrombolytic therapy in unstable patients with acute pulmonary embolism: saves lives but underused. Am J Med. 2012; 125(5): 465–470. PMID: 22325236. DOI:10.1016/j.amjmed.2011.10.015.; https://www.jnmp.ru/jour/article/view/433

  5. 5
    Academic Journal

    المصدر: Russian Sklifosovsky Journal "Emergency Medical Care"; Том 6, № 1 (2017); 13-19 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 6, № 1 (2017); 13-19 ; 2541-8017 ; 2223-9022 ; 10.23934/2223-9022-2017-6-1

    وصف الملف: application/pdf

    Relation: https://www.jnmp.ru/jour/article/view/338/406; Савельев В.С., Гельфанд Б.Р. (ред.) Сепсис: классификация, клинико-диагностическая концепция и лечение: практическое руководство. 3-е изд., доп. и пераб. М.: Медицинское информационное агентство, 2013. 360 с.; Lewis D.H., Chan D.L., Pinheiro D., et al. The immunopathology of sepsis: pathogen recognition, systemic inflammation, the compensatory antiinflammatory respons, and regulatory T сells. J. Vet. Intern. Med. 2012; 26(3): 457–482. PMID: 22428780 DOI:10.1111/j.1939-1676.2012.00905.x.; Antonelli M. Sepsis and septic shock: pro-inflammatory or antiinflammatory state? J. Chemother. 1999; 11(6): 536–540. PMID: 10678797 DOI:10.1179/joc.1999.11.6.536.; Cavaillon J.M., Annane D. Compartmentalization of the inflammatory response in sepsis and SIRS. J. Endotoxin Res. 2006; 12(3): 151–170. PMID: 16719987 DOI:10.1179/096805106X102246.; Marshall J.C., Reinhart K. Biomarkers of sepsis. Crit. Care Med. 2009; 37(7): 2290–2298. PMID: 19487943 DOI:10.1097/CCM.0b013e3181a02afc.; Козлов В.К. Сепсис: этиология, иммунопатогенез, концепция современной иммунотерапии. СПб.: Диалект, 2006. 300 с.; Boomer J.S., To K., Chang K.C., et al. Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA. 2011; 306(23): 2594–2605. PMID: 22187279 DOI:10.1001/jama.2011.1829.; Петров Р.В. Иммунология и иммуногенетика. М.: Медицина, 1976. 336 с.; Reinhart K., Meisner M. Biomarkers in the critically ill patient: procalcitonin. Crit. Care Clin. 2011; 27(2): 253–263. PMID: 21440200 DOI:10.1016/j.ccc.2011.01.002.; Hotchkiss R.S., Nicholson D.W. Apotosis and caspases regulate death and inflammation in sepsis. Nat. Rev. Immunol. 2006; 6(11): 813–822. PMID: 17039247 DOI:10.1038/nri1943.; Gaini S., Koldkjaer O.G., Pedersen C., Pedersen S.S. Procalcitonin, lipopolysac charide-binding protein, interleukin-6 and C-reactive protein in community-acquired infections and sepsis: a prospective study. Crit. 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