المؤلفون: M. A. Fomich, A. V. Bekish, O. L. Sharko, K. N. Prokhorevich, V. V. Shmanai, М. А. Фомич, А. В. Бекиш, О. Л. Шарко, К. Н. Прохоревич, В. В. Шманай

المساهمون: Authors are grateful to T. S. Zatsepin («Skoltech», Moscow) for his help in registering mass spectra of the conjugates., Авторы благодарят Т. С. Зацепина («Сколтех», Москва) за помощь в регистрировании масс- спектров конъюгатов.

المصدر: Proceedings of the National Academy of Sciences of Belarus, Chemical Series; Том 54, № 1 (2018); 46-57 ; Известия Национальной академии наук Беларуси. Серия химических наук; Том 54, № 1 (2018); 46-57 ; 2524-2342 ; 1561-8331 ; 10.29235/1561-8331-2018-54-1

مصطلحات موضوعية: клик-химия, oligonucleotides, bioconjugates, click chemistry, олигонуклеотиды, биоконъюгаты

وصف الملف: application/pdf

Relation: https://vestichem.belnauka.by/jour/article/view/303/289; Modifications in Therapeutic Oligonucleotides Improving the Delivery / I. Dovydenko [et al.]. – 2016. – P. 319–337.; Molecular aptamers for drug delivery / W. Tan [et al.] // Trends Biotechnol. – 2011. – Vol. 29, № 12. – P. 634–640.; Gene therapy clinical trials worldwide to 2012 – an update / S. L. Ginn [et al.] // J. Gene Med. – 2013. – Vol. 15, № 2. – P. 65–77.; Walther, W. Viral Vectors for Gene Transfer / W. Walther, U. Stein // Drugs. – 2000. – Vol. 60, № 2. – P. 249–271.; Thomas, C. E. Progress and problems with the use of viral vectors for gene therapy / C. E. Thomas, A. Ehrhardt, M. A. Kay // Nat. Rev. Genet. – 2003. – Vol. 4, № 5 – P. 346–358.; Kay, M. A. State-of-the-art gene-based therapies: the road ahead / M. A. Kay // Nat. Rev. Genet. – 2011. – Vol. 12, № 5. – P. 316–328.; Recent advances in characterization of nonviral vectors for delivery of nucleic acids: impact on their biological performance / C. Oliveira [et al.] // Expert Opin. Drug Deliv. – 2015. – Vol. 12, № 1. – P. 27–39.; Balazs, D. A. Liposomes for Use in Gene Delivery / D. A. Balazs, W. Godbey // J. Drug Deliv. – 2011. – Vol. 2011. – P. 1–12.; Dizaj, S. A sight on the current nanoparticle-based gene delivery vectors / S. Dizaj, S. Jafari, A. Khosroushahi // Nanoscale Res. Lett. – 2014. – Vol. 9, № 1. – P. 252.; Kuo, W.-T. Intracellular trafficking, metabolism and toxicity of current gene carriers. / W.-T. Kuo, H.-Y. Huang, Y.-Y. Huang // Curr. Drug Metab. – 2009. – Vol. 10, № 8. – P. 885–894.; Lipid Conjugated Oligonucleotides: A Useful Strategy for Delivery / M. Raouane [et al.] // Bioconjug. Chem. – 2012. – Vol. 23, № 6. – P. 1091–1104.; Synthesis of Oligonucleotides Carrying Amino Lipid Groups at the 3′-End for RNA Interference Studies / S. Grijalvo [et al.] // J. Org. Chem. – 2010. – Vol. 75, № 20. – P. 6806–6813.; Synthesis of Lipid-Oligonucleotide Conjugates for RNA Interference Studies / S. Grijalvo [et al.] // Chem. Biodivers. – 2011. – Vol. 8, № 2. – P. 287–299.; Synthesis, Characterization, and in Vivo Delivery of siRNA-Squalene Nanoparticles Targeting Fusion Oncogene in Papillary Thyroid Carcinoma / M. Raouane [et al.] // J. Med. Chem. – 2011. – Vol. 54, № 12. – P. 4067–4076.; Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol / K. Nishina [et al.] // Mol. Ther. – 2008. – Vol. 16, № 4. – P. 734–740.; Cholesteryl-conjugated oligonucleotides: synthesis, properties, and activity as inhibitors of replication of human immunodeficiency virus in cell culture. / R.L. Letsinger [et al.] // Proc. Natl. Acad. Sci. U.S.A. – 1989. – Vol. 86, № 17.; Lung Delivery Studies Using siRNA Conjugated to TAT(48−60) and Penetratin Reveal Peptide Induced Reduction in Gene Expression and Induction of Innate Immunity / S.A. Moschos [et al.] // Bioconjug. Chem. – 2007. – Vol. 18, № 5. – P. 1450–1459.; Synthesis and silencing properties of siRNAs possessing lipophilic groups at their 3’-termini / Y. Ueno [et al.] // Nucleic Acids Symp. Ser. – 2008. – Vol. 52, № 1. – P. 503–504.; Habus, I. Synthesis, hybridization properties, nuclease stability, and cellular uptake of the oligonucleotide– amino-beta-cyclodextrins and adamantane conjugates. / I. Habus, Q. Zhao, S. Agrawal // Bioconjug. Chem. – Vol. 6, № 4. – P. 327–331.; 3’-End conjugates of minimally phosphorothioate-protected oligonucleotides with 1-O-hexadecylglycerol: synthesis and anti-ras activity in radiation-resistant cells / A. Rait [et al.] // Bioconjug. Chem. – Vol. 11, № 2. – P. 153–160.; Acridine- and cholesterol-derivatized solid supports for improved synthesis of 3’-modified oligonucleotides. / M. W. Reed [et al.] // Bioconjug. Chem. – Vol. 2, № 4. – P. 217–225.; Synthesis of cholesteryl supports and phosphoramidites containing a novel peptidyl linker for automated synthesis of triple-helix forming oligonucleotides (TFOs). / H. Vu [et al.] // Nucleic Acids Symp. Ser. – 1993, № 29. – P. 19–20.; Vu, H. Synthesis and Properties of Cholesteryl-Modified Triple-Helix Forming Oligonucleotides Containing a Triglycyl Linker / H. Vu, T.S. Hill, K. Jayaraman // Bioconjug. Chem. – 1994. – Vol. 5, № 6. – P. 666–668.; Will, D. W. Attachment of vitamin E derivatives to oligonucleotides during solid-phase synthesis / D. W. Will, T. Brown // Tetrahedron Lett. – 1992. – Vol. 33, № 19. – P. 2729–2732.; Synthesis and physical properties of anti-HIV antisense oligonucleotides bearing terminal lipophilic groups. / C. MacKellar [et al.] // Nucleic Acids Res. – 1992. – Vol. 20, № 13. – P. 3411–347.; Structure-activity relationships of cytotoxic cholesterol-modified DNA duplexes. / M. W. Reed [et al.] // J. Med. Chem. – 1995. – Vol. 38, № 22. – P. 4587–4596.; Matysiak, S. Acetal Oligonucleotide Conjugates in Antisense Strategy / S. Matysiak, R. Frank, W. Pfleiderer // Nucleosides and Nucleotides. – 1997. – Vol. 16, № 5–6. – P. 855–861.; Godeau, G. Lipid-Conjugated Oligonucleotides via “Click Chemistry” Efficiently Inhibit Hepatitis C Virus Translation / G. Godeau, C. Staedel, P. Barthélémy // J. Med. Chem. – 2008. – Vol. 51, № 15. – P. 4374–4376.; Azide Phosphoramidite in Direct Synthesis of Azide-Modified Oligonucleotides / M. A. Fomich [et al.] // Org. Lett. – 2014. – Vol. 16, № 17. – P. 4590–4593.; Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress / A. Y. Andreyev [et al.] // Free Radic. Biol. Med. – 2015. – Vol. 82. – P. 63–72.; Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation / S. Hill [et al.] // Free Radic. Biol. Med. – 2012. – Vol. 53, № 4. – P. 893–906.; Dussault, P. H. Total Synthesis of the Alkoxydioxines (+)- and (−)-Chondrillin and (+)- and (−)-Plakorin via Singlet Oxygenation/Radical Rearrangement / P. H. Dussault, C. T. Eary, K. R. Woller // J. Org. Chem. – 1999. – Vol. 64, № 6. – P. 1789–1797.; https://vestichem.belnauka.by/jour/article/view/303

الاتاحة: https://vestichem.belnauka.by/jour/article/view/303
https://doi.org/10.29235/1561-8331-2018-54-1-46-57

المؤلفون: M. A. Fomich, O. L. Sharko, V. V. Shmanai, М. А. Фомич, О. Л. Шарко, В. В. Шманай

المصدر: Proceedings of the National Academy of Sciences of Belarus, Chemical Series; № 4 (2017); 48-54 ; Известия Национальной академии наук Беларуси. Серия химических наук; № 4 (2017); 48-54 ; 2524-2342 ; 1561-8331 ; undefined

مصطلحات موضوعية: сетчатка глаза, lipid peroxidation, aminoacids, glucosamine, choline, eye retina, липидное окисление, аминокислоты, глюкозамин, холин

وصف الملف: application/pdf

Relation: https://vestichem.belnauka.by/jour/article/view/288/275; Loftsson, T. Pharmaceutical applications of cyclodextrins: basic science and product development / T. Loftsson, M. E. Brewster // J. Pharm. Pharmacol. – 2010. – Vol. 62, № 11. – P. 1607–1621.; Kalepu, S. Insoluble drug delivery strategies: review of recent advances and business prospects / S. Kalepu, V. Nekkanti // Acta Pharm. Sin. B. – 2015. – Vol. 5, № 5. – P. 442–453.; Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress / S. Hill [et al.] // Free Radic. Biol. Med. – 2011. – Vol. 50, № 1 – P. 130–138.; Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation / S. Hill [et al.] // Free Radic. Biol. Med. – 2012. – Vol. 53, № 4. – P. 893–906.; Isotope-reinforced polyunsaturated fatty acids protect mitochondria from oxidative stress / A.Y. Andreyev [et al.] // Free Radic. Biol. Med. – 2015. – Vol. 82. – P. 63–72.; Prodrug Strategies in Ocular Drug Delivery / M. Barot [et al.] // Med. Chem. (Los. Angeles). – 2012. – Vol. 8, № 4. – P. 753–768.; Tirucherai, G. S. Corneal permeation of ganciclovir: mechanism of ganciclovir permeation enhancement by acyl ester prodrug design / G. S. Tirucherai, C. Dias, A. K. Mitra // J. Ocul. Pharmacol. Ther. – 2002. – Vol. 18, № 6 – P. 535–548.; Suzuki, E. R. Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations. / E. R. Suzuki, C. L. B. Suzuki // Clin. Ophthalmol. – 2010. – Vol. 4 – P. 1165–1171.; Camber, O. Factors influencing the corneal permeability of prostaglandin F2α and its isopropyl ester in vitro / O. Camber, P. Edman // Int. J. Pharm. – 1987. – Vol. 37, № 1–2 – P. 27–32.; Mannermaa, E. Drug transport in corneal epithelium and blood–retina barrier: Emerging role of transporters in ocular pharmacokinetics / E. Mannermaa, K.-S. Vellonen, A. Urtti // Adv. Drug Deliv. Rev. – 2006. – Vol. 58, № 11 – P. 1136–1163.; Design and Synthesis of Glycoside Inhibitors of Glioma and Melanoma Growth / I. García-Álvarez [et al.] // J. Med. Chem. – 2007. – Vol. 50, № 2 – P. 364–373.; Banno, T. pH-Sensitive Self-Propelled Motion of Oil Droplets in the Presence of Cationic Surfactants Containing Hydrolyzable Ester Linkages / T. Banno, R. Kuroha, T. Toyota // Langmuir. – 2012. – Vol. 28, № 2 – P. 1190–1195.; Drug and Gene Delivery to the Back of the Eye: From Bench to Bedside / C. L. Rowe-Rendleman [et al.] // Investig. Opthalmology Vis. Sci. – 2014. – Vol. 55, № 4 – P. 2714.; https://vestichem.belnauka.by/jour/article/view/288; undefined

الاتاحة: https://vestichem.belnauka.by/jour/article/view/288