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1Academic Journal
المؤلفون: L. Korolevskaya B., E. Saidakova V., V. Vlasova V., C. Shmagel V., Л. Королевская Б., Е. Сайдакова В., В. Власова В., К. Шмагель В.
المساهمون: Работа выполнена в рамках государственного задания «Механизмы регуляции иммунной системы» (номер госрегистрации темы ААААА19–119112290007–7) с использованием оборудования ЦКП «Исследования материалов и вещества» ПФИЦ УрО РАН.
المصدر: HIV Infection and Immunosuppressive Disorders; Том 13, № 3 (2021); 52-60 ; ВИЧ-инфекция и иммуносупрессии; Том 13, № 3 (2021); 52-60 ; 2077-9828 ; 10.22328/2077-9828-2021-13-3
مصطلحات موضوعية: HIV-infection, hepatitis C, mitochondria, CD4+ T-lymphocytes, antiretroviral therapy, discordant response, ВИЧ-инфекция, гепатит С, митохондрии, CD4+ Т-лимфоциты, антиретровирусная терапия, дискордантный ответ
وصف الملف: application/pdf
Relation: https://hiv.bmoc-spb.ru/jour/article/view/659/450; Autran B., Carcelaint G., Li T.S., Gorochov G., Blanc C., Renaud M., Durali, M., Mathez D., Calvez V., Leibowitch J., Katlama C., Debre P. Restoration of the immune system with anti-retroviral therapy // Immunol. Lett. 1999. Vol. 66, No. 1–3. Р. 207–211.; Gaardbo J.C., Hartling H. J., Gerstoft J., Nielsen S.D. Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions // Clin. Dev. Immunol. 2012. Vol. 2012. Р. 670957. doi:10.1155/2012/670957.; Lederman M.M., Calabrese L., Funderburg N.T., Clagett B., Medvik K., Bonilla H., Gripshover B., Salata R.A., Taege A., Lisgaris M., McComsey G.A., Kirchner E., Baum J., Shive C., Asaad R., Kalayjian R.C., Sieg S.F., Rodriguez B. Immunologic failure despite suppressive antiretroviral therapy is related to activation and turnover of memory CD4 cells // J. Infect. Dis. 2011. Vol. 204, No. 8. Р. 1217–1226. doi:10.1093/infdis/jir507.; Lapadula G., Cozzi-Lepri A., Marchetti G., Antinori A., Chiodera A., Nicastri E., Parruti G., Galli M., Gori A., Monforte Ad Icona Foundation Study. Risk of clinical progression among patients with immunological nonresponse despite virological suppression after combination antiretroviral treatment // AIDS. 2013. Vol. 27, No. 5. Р. 769–779. doi:10.1097/QAD.0b013e32835cb747.; Santin M., Mestre M., Shaw E., Barbera M.J., Casanova A., Niubo J., Bolao F., Podzamczer D., Gudiol F. Impact of hepatitis C virus coinfection on immune restoration during successful antiretroviral therapy in chronic human immunodeficiency virus type 1 disease // Eur. J. Clin. Microbiol. Infect. Dis. 2008. Vol. 27, No. 1. Р. 65–73. doi:10.1007/s10096-007-0384-3.; Chen T.Y., Ding E.L., Seage Iii G.R., Kim A.Y. Meta-analysis: increased mortality associated with hepatitis C in HIV-infected persons is unrelated to HIV disease progression // Clin. Infect. Dis. 2009. Vol. 49, No. 10. Р. 1605–1615. doi:10.1086/644771.; Kuhlbrandt W., Structure and function of mitochondrial membrane protein complexes // BMC Biol. 2015. Vol. 13. Р. 89. doi:10.1186/s12915-015-0201-x.; Gottlieb E., Armour S.M., Harris M.H., Thompson C.B. Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis // Cell Death Differ. 2003. Vol. 10, No. 6. Р. 709–717. doi:10.1038/sj.cdd.4401231.; Palikaras K., Tavernarakis N. Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis // Exp. Gerontol. 2014. Vol. 56. Р. 182–188. doi:10.1016/j.exger.2014.01.021.; Petrovas C., Mueller Y.M., Dimitriou I.D., Altork S.R., Banerjee A., Sklar P., Mounzer K.C., Altman J.D., Katsikis P.D. Increased mitochondrial mass characterizes the survival defect of HIV-specific CD8(+) T cells // Blood. 2007. Vol. 109, No. 6. Р. 2505–2513. doi:10.1182/blood-2006-05-021626.; Yu F., Hao Y., Zhao H., Xiao J., Han N., Zhang Y., Dai G., Chong X., Zeng H., Zhang F. Distinct Mitochondrial Disturbance in CD4+T and CD8+T Cells From HIV-Infected Patients // J. Acquir. Immune Defic. Syndr. 2017. Vol. 74, No. 2. Р. 206–212. doi:10.1097/QAI.0000000000001175.; Masson J.J.R., Murphy A.J., Lee M.K.S., Ostrowski M., Crowe S.M., Palmer C.S. Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy // PLoS One. 2017. Vol. 12, No. 8. Р. e0183931. doi:10.1371/journal.pone.0183931.; Sternfeld T., Schmid M., Tischleder A., Mudra S., Schlamp A., Kost B.P., Gruber R., Youle M., Bogner J.R., Goebel F.D. The influence of HIV infection and antiretroviral therapy on the mitochondrial membrane potential of peripheral mononuclear cells // Antivir. Ther. 2007. Vol. 12, No. 5. Р. 769–778.; Deguit C.D.T., Hough M., Hoh R., Krone M., Pilcher C.D., Martin J.N., Deeks S.G., McCune J.M., Hunt P.W., Rutishauser R.L. Some Aspects of CD8(+) T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection // Jaids-Journal of Acquired Immune Deficiency Syndromes. 2019. Vol. 82, No. 2. Р. 211–219. doi:10.1097/Qai.0000000000002121.; Barbaro G., Di Lorenzo G., Asti A., Ribersani M., Belloni G., Grisorio B., Filice G., Barbarini G. Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: ultrastructural and biochemical findings // Am. J. Gastroenterol. 1999. Vol. 94, No. 8. Р. 2198–2205. doi:10.1111/j.1572-0241.1999.01294.x.; Piccoli C., Quarato G., Ripoli M., D’Aprile A., Scrima R., Cela O., Boffoli D., Moradpour D., Capitanio N. HCV infection induces mitochondrial bioenergetic unbalance: causes and effects // Biochim. Biophys. Acta. 2009. Vol. 1787, No. 5. 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Vol. 98, No. 1. Р. 115–124. doi:10.1016/s0092-8674(00)80611-x.; Perry C.G.R., Hawley J.A. Molecular Basis of Exercise-Induced Skeletal Muscle Mitochondrial Biogenesis: Historical Advances, Current Knowledge, and Future Challenges // Cold Spring Harb. Perspect. Med. 2018. Vol. 8, No. 9. doi:10.1101/cshperspect.a029686.; Gonzalez V.D., Falconer K., Blom K.G., Reichard O., Morn B., Laursen A.L., Weis N., Alaeus A., Sandberg J.K. High levels of chronic immune activation in the T-cell compartments of patients coinfected with hepatitis C virus and human immunodeficiency virus type 1 and on highly active antiretroviral therapy are reverted by alpha interferon and ribavirin treatment // J. Virol. 2009. Vol. 83, No. 21. Р. 11407–11411. doi:10.1128/JVI.01211-09.; Akkaya B., Roesler A.S., Miozzo P., Theall B.P., Al Souz J., Smelkinson M.G., Kabat J., Traba J., Sack M.N., Brzostowski J. A., Pena M., Dorward D.W., Pierce S.K., Akkaya M. Increased Mitochondrial Biogenesis and Reactive Oxygen Species Production Accompany Prolonged CD4(+) T Cell Activation // J. Immunol. 2018. Vol. 201, No. 11. Р. 3294–3306. doi:10.4049/jimmunol.1800753.; Cheng C.F., Ku H.C., Lin H. PGC-1alpha as a Pivotal Factor in Lipid and Metabolic Regulation // Int. J. Mol. Sci. 2018. Vol. 19, No. 11. doi:10.3390/ijms19113447.; https://hiv.bmoc-spb.ru/jour/article/view/659
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2Academic Journal
المؤلفون: K. Shmagel V., V. Chereshnev A., К. Шмагель В., В. Черешнев А.
المساهمون: Работа выполнена при поддержке гранта РФФИ № 17-54-30006.
المصدر: HIV Infection and Immunosuppressive Disorders; Том 10, № 4 (2018); 25-36 ; ВИЧ-инфекция и иммуносупрессии; Том 10, № 4 (2018); 25-36 ; 2077-9828 ; 10.22328/2077-9828-2018-10-4
مصطلحات موضوعية: HIV infection, co-infection with hepatitis C virus, fibrosis and cirrhosis of the liver, antiretroviral therapy, microbial translocation, systemic inflammation, HIV non-associated diseases, ВИЧ-инфекция, коинфекция вирусом гепатита C, фиброз и цирроз печени, антиретровирусная терапия, микробная транслокация, системное воспаление, СПИД-неассоциированные заболевания
وصف الملف: application/pdf
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3Academic Journal
المؤلفون: L. Korolevskaya B., E. Saydakova V., K. Shmagel V., Л. Королевская Б., Е. Сайдакова В., К. Шмагель В.
المساهمون: Работа выполнена в рамках государственного задания «Механизмы регуляции иммунной системы», номер госрегистрации темы: 01201353248.
المصدر: HIV Infection and Immunosuppressive Disorders; Том 11, № 3 (2019); 57-63 ; ВИЧ-инфекция и иммуносупрессии; Том 11, № 3 (2019); 57-63 ; 2077-9828 ; 10.22328/2077-9828-2019-11-3
مصطلحات موضوعية: HIV infection, hepatitis C, cytokines, chronic inflammation, liver injury, ВИЧ-инфекция, гепатит С, цитокины, хроническое воспаление, повреждение печени
وصف الملف: application/pdf
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