المؤلفون: И. Ю. Торшин, О. А. Громова, О. А. Лиманова

المصدر: Репродуктивная эндокринология, Vol 0, Iss 54, Pp 123-129 (2020)

مصطلحات موضوعية: vitex agnus-castus, standardized extracts, phytoestrogens, dopamine receptors modulation, hyperprolactinemia reduction, Gynecology and obstetrics, RG1-991

وصف الملف: electronic resource

Relation: http://reproduct-endo.com/article/view/214799; https://doaj.org/toc/2309-4117; https://doaj.org/toc/2411-1295

URL الوصول: https://doaj.org/article/b24aad3d5030434a8bb15dcd88f76c43

المؤلفون: О. А. Громова, А. Г. Калачева, И. Ю. Торшин, Н. В. Юдина, Е. Ю. Егорова, Т. Р. Гришина, В. А. Семенов, Н. В. Прозорова, Т. Ю. Суханова, А. Ю. Белинская

المصدر: Архивъ внутренней медицины, Vol 0, Iss 3, Pp 6-10 (2014)

مصطلحات موضوعية: mg2+ deficiency, blood serum, blood plasma, diagnostic, hypodiagnostic, saline, urine, nails, hair, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: https://www.medarhive.ru/jour/article/view/293; https://doaj.org/toc/2226-6704; https://doaj.org/toc/2411-6564

URL الوصول: https://doaj.org/article/878db26c17554b8ba3475c99d57bde59

المؤلفون: О. А. Громова, А. Г. Калачева, И. Ю. Торшин, У. Е. Грустливая, Н. В. Прозорова, Е. Ю. Егорова, Т. Р. Гришина, Т. Ю. Суханова, А. Ю. Белинская

المصدر: Архивъ внутренней медицины, Vol 0, Iss 2, Pp 5-10 (2014)

مصطلحات موضوعية: mg2+ deficiency, blood serum, blood plasma, diagnostic, hypodiagnostic, saline, urine, nails, hair, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: https://www.medarhive.ru/jour/article/view/275; https://doaj.org/toc/2226-6704; https://doaj.org/toc/2411-6564

URL الوصول: https://doaj.org/article/4c4bcc0218ef43c1aa1b8e79e08f8819

المؤلفون: T. E. Bogacheva, O. A. Gromova, I. Yu. Torshin, V. I. Demidov, A. G. Kalacheva, A. A. Garanin, I. V. Gogoleva, L. E. Fedotova, O. A. Limanova, А. N. Mnatsakanyan, N. Yu. Zhidomorov, T. R. Grishina, Т. Е. Богачева, О. А. Громова, И. Ю. Торшин, В. И. Демидов, А. Г. Калачева, А. А. Гаранин, И. В. Гоголева, Л. Э. Федотова, О. А. Лиманова, А. Н. Мнацаканьян, Н. Ю. Жидоморов, Т. Р. Гришина

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: ГПЧ, metabolic-associated fatty liver disease, МAFLD, iron overload, fructose, palm oil, polypeptide therapy, human placenta hydrolyzate, HPH, неалкогольная жировая болезнь печени, МАЖБП, перегрузка железом, фруктоза, пальмовое масло, гидролизат плаценты человека

وصف الملف: application/pdf

Relation: https://www.pharmacoeconomics.ru/jour/article/view/1118/579; Райхельсон К.Л., Маев М.В., Жаркова М.С. и др. Жировая болезнь печени: новая номенклатура и ее адаптация в Российской Федерации. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2024; 34 (2): 35–44. https://doi.org/10.22416/1382-4376-2024-961.; Торшин И.Ю., Громова О.А., Богачева Т.Е. Систематический анализ взаимосвязей между неалкогольной жировой болезнью печени и перегрузкой тканей железом: перспективные направления применения полипептидной терапии. Экспериментальная и клиническая гастроэнтерология. 2023; 10: 139–52. https://doi.org/10.31146/1682-8658-ecg-218-10-139-152.; Торшин И.Ю., Громова О.А., Тихонова О.В., Чучалин А.Г. О молекулярных механизмах воздействия пептидов стандартизированного гидролизата плаценты на функционирование митохондрий. Терапевтический архив. 2023; 95 (12): 1133–40. https://doi.org/10.26442/00403660.2023.12.202494.; Богачева Т.Е., Калачева А.Г., Громова О.А. и др. Изучение эффективности препарата Лаеннек при повреждении печени пальмовым маслом у крыс. Фармакокинетикаифармакодинамика. 2023;4:23–31. https://doi.org/10.37489/2587-7836-2023-4-23-31.; Тран В.Т., Торшин И.Ю., Громова О.А. Открытое контролируемое исследование эффективности и безопасности применения Лаеннека для улучшения функции печени у пациентов с неалкогольной жировой болезнью печени. Экспериментальная и клиническая гастроэнтерология. 2023; 8: 48–56. https://doi.org/10.31146/1682-8658-ecg-216-8-48-56.; Громова О.А., Торшин И.Ю., Максимов В.А. и др. Пептиды в составе препарата Лаеннек,способствующие устранению гиперферритинемии и перегрузки железом. ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология. 2020; 13 (4): 413–25. https://doi.org/10.17749/2070-4909/farmakoekonomika.2020.070.; Максимов В.А., Торшин И. Ю., Чучалин А. Г. и др. Эффективность и безопасность полипептидного препарата (Лаеннек) в терапии COVID-19. Экспериментальная и клиническая гастроэнтерология. 2020; 6: 55–63. https://doi.org/10.31146/1682-8658-ecg-178-6-55-63.; Винницкая Е.В., Сандлер Ю.Г., Салиев К.Г. и др. Эффективность гидролизата плаценты человека при метаболически ассоциированной жировой болезни печени н астадии фиброза (пилотноеисследование). Терапевтический архив. 2024; 96 (2): 107–16. https://doi.org/10.26442/00403660.2024.02.202582.; Zhuo Z., Fan S., Hu K., et al. Analysis of digital profiling of duodenal transcriptome gene expression in SD rats injected with iron sulfate or iron glycine chelate through a probe. Sci Rep. 2016; 6: 37923. https://doi.org/10.1038/srep37923.; Luo G., Xiang L., Xiao L. Acetyl-CoA deficiency is involved in the regulation of iron overload on lipid metabolism in apolipoprotein E knockout mice. Molecules. 2022; 27 (15): 4966. https://doi.org/10.3390/molecules27154966.; Hilton S., Sabaratnam R., Drakesmith H., Karpe, F. Metabolism of iron, glucose and fats and obesity: the relationship. Int J Obes. 2023; 47 (7): 554–63. https://doi.org/10.1038/s41366-023-01299-0.; Jensen T., Abdelmalek M.F., Sullivan S., et al. Fructose and sugar: the main mediators of non-alcoholic fatty liver disease. J Hepatol. 2018; 68 (5): 1063–75. https://doi.org/13.1016/j.jhep.2018.01.019.; Ma J., Sloan M., Fox K.S., et al. Consumption of sugar-sweetened beverages is associated with the breakdown of abdominal fat in healthy adults. J Nutr. 2014; 144 (8): 1283–90. https://doi.org/10.3945/jn.113.188599.; Di Stefano J.K. Fructose-mediated effect on gene expression and epigenetic mechanisms associated with the pathogenesis of NAFLD. Cell Mol Life Sci. 2020; 77 (11): 2079–90. https://doi.org/10.1007/s00018-019-03390-0.; Vos, M.B.; Lavin, J.E. Dietary fructose in non-alcoholic fatty liver disease. Hepatology. June 2013; 57(6):2525- 31. https://doi.org/10.1002/hep.26299. Epub 2013 May 1. PMID: 23390127.; Kanerva N., Sandboge S., Kaartinen N.E., et al. Higher consumption of fructose is inversely proportional to the risk of non-alcoholic golic fatty liver disease in elderly Finns 1-4 years. Am J Clin Nutr. 2014; 100: 1133–41. https://doi.org/10.3945/ajcn.114.086074.; Ma J., Fox K.S., Jacques F., Speliotes, E.K., et al. Sugar-sweetened beverage, diet soda, and fatty liver disease in the Framingham Heart Study cohorts. J Hepatol. 2015; 63 (2): 462–9. https://doi.org/10.1016/j.jhep.2015.03.032; Шептулина А.Ф., Голубева Ю.А., Драпкина О.М. Фруктоза и ее влияние на обмен веществ и риск развития неалкогольной жировой болезни печени. Доказательная гастроэнтерология. 2023; 12 (1): 85–92. https://doi.org/10.17116/dokgastro20231201185.; Wu J., Yang T., Wang C. et al. Laennec protects murine from concavalin A-induced liver injury through inhibition of inflammamory reactions and hepatocyte apoptosis. Biol Pharm Bull. 2008; 31 (11): 2040–4. https://doi.org/10.1248/bpb.31.2040.; Jung J.C., Lee H.J., Lee J.M, et al. Placenta extract promote liverregeneration in CCI4-injured liver rat model. Int Immunopharmacol. 2011; 11 (8): 976–84. https://doi.org/10.1016/j.intimp.2011.02.012.; Yamauchi A., Kamiyoshi A., Koyama T., et al. Placental extract ameliorates non-alcoholic steatohepatitis (NASH) by exerting protective effects on endothelial cells. Heliyon. 2017; 3 (9): e00416. https://doi.org/10.1016/j.heliyon.2017.e00416.; https://www.pharmacoeconomics.ru/jour/article/view/1118

الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/1118
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.274

المؤلفون: P. A. Galenko-Yaroshevsky, A. V. Sergeeva, I. Yu. Torshin, A. N. Gromov, I. A. Reyer, O. A. Gromova, B. A. Trofimov, L. N. Parshina, R. A. Murashko, A. V. Zadorozhniy, A. V. Zelenskaya, S. N. Sergeev, Yu. V. Tovkach, O. N. Gulevskaya, I. V. Sholl, П. А. Галенко-Ярошевский, А. В. Сергеева, И. Ю. Торшин, А. Н. Громов, И. А. Рейер, О. А. Громова, Б. А. Трофимов, Л. Н. Паршина, Р. А. Мурашко, А. В. Задорожний, А. В. Зеленская, Н. С. Сергеев, Ю. В. Товкач, О. Н. Гулевская, И. В. Шоль

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: интеллектуальный анализ данных, zinc-containing compounds, anti-inflammatory drug, adverse effects, chemoinformatics, pharmacoinformatics, data mining, цинк-содержащие соединения, противовоспалительный препарат, побочные эффекты, хемоинформатика, фармакоинформатика

وصف الملف: application/pdf

Relation: https://www.pharmacoeconomics.ru/jour/article/view/1117/578; Shetty A., Delanerolle G., Cavalini H., et al. A systematic review and network meta-analysis of pharmaceutical interventions used to manage chronic pain. Sci Rep. 2024; 14 (1): 1621. http://doi.org/10.1038/s41598-023-49761-3.; Громова О.А., Торшин И.Ю., Путилина М.В. и др. Хемореактомный анализ центральных механизмов нестероидных противовоспалительных препаратов. Журнал неврологии и психиатрии им. С.С. Корсакова. 2020; 120 (1): 70–7. https://doi.org/10.17116/jnevro202012001170.; Ali G., Deeba F., Rashid U., et al. In vivo effects of a selected thiourea derivative 1-(2-chlorobenzoyl)-3-(2,3-dichlorophenyl) against nociception, inflammation and gastric ulcerogenicity: biochemical, histopathological and in silico approaches. Biomed Pharmacother. 2024; 174: 116544. http://doi.org/10.1016/j.biopha.2024.116544.; Santos L.H., Feres C.A., Melo F.H., et al. Anti-inflammatory, antinociceptive and ulcerogenic activity of a zinc-diclofenac complex in rats. Braz J Med Biol Res. 2004; 37 (8): 1205–13. http://doi.org/10.1590/s0100-879x2004000800011.; Sukul A., Poddar S.K., Haque S., et al. Synthesis, characterization and comparison of local analgesic, anti-inflammatory, anti-ulcerogenic activity of copper and zinc complexes of indomethacin. Antiinflamm Antiallergy Agents Med Chem. 2017; 15 (3): 221–33. http://doi.org/10.2174/1871523016666170217103402.; Jarosz M., Szkaradek N., Marona H., et al. Evaluation of anti-inflammatory and ulcerogenic potential of zinc-ibuprofen and zinc-naproxen complexes in rats. Inflammopharmacology. 2017; 25 (6): 653–63. http://doi.org/10.1007/s10787-017-0361-0.; Gaweł M., Lipkowska A., Herman M., et al. Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats. Pharmacol Rep. 2014; 66 (5): 862–6. http://doi.org/10.1016/j.pharep.2014.05.007.; Торшин И.Ю., Громова О.А., Федотова Л.Э., Громов А.Н. Сравнительный хемореактомный анализ декскетопрофена, кетопрофена и диклофенака. Неврология, нейропсихиатрия, психосоматика. 2018; 10 (1): 47–54. DOI: http://doi.org/10.14412/2074-2711-2018-1-47-54.; Торшин И.Ю., Громова О.А., Стаховская Л.В., Семёнов В.А. Хемореактомный анализ молекул толперизона, тизанидина и баклофена: холинолитические, спазмолитические и анальгетические механизмы действия. Неврология, нейропсихиатрия, психосоматика. 2018; 10 (4): 72–80. http://doi.org/10.14412/2074-2711-2018-4-72-80.; Торшин И.Ю. О задачах оптимизации, возникающих при применении топологического анализа данных к поиску алгоритмов прогнозирования с фиксированными корректорами. Информатика и еe применения. 2023; 17 (2): 2–10. http://doi.org/10.14357/19922264230201.; Torshin I.Yu., Rudakov K.V. On the procedures of generation of numerical features over partitions of sets of objects in the problem of predicting numerical target variables. Pattern Recognit Image Anal. 2019; 29 (4): 654–67. https://doi.org/10.1134/S1054661819040175.; Торшин И.Ю., Громова О.А., Чучалин А.Г., Журавлев Ю.И. Хемореактомный скрининг воздействия фармакологических препаратов на SARS-CoV-2 и виром человека как информационная основа для принятия решений по фармакотерапии COVID-19. ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология. 2021; 14 (2): 191–211. https://doi.org/10.17749/2070-4909/farmakoekonomika.2021.078.; Торшин И.Ю., Громова О.А. Экспертный анализ данных в молекулярной фармакологии. М.: МЦНМО; 2012: 747 с.; Baumgardner K.R., Sulfaro M.A. The anti-inflammatory effects of human recombinant copper-zinc superoxide dismutase on pulp inflammation. J Endod. 2001; 27 (3): 190–5. http://doi.org/10.1097/00004770-200103000-00014.; Громова О.А. Торшин И.Ю. 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BMJ Open. 2021; 11 (11): e047474. http://doi.org/10.1136/bmjopen-2020-047474.; Briassoulis G., Briassoulis P., Ilia S., et al. The anti-oxidative, anti-inflammatory, anti-apoptotic, and anti-necroptotic role of zinc in COVID-19 and sepsis. Antioxidants. 2023; 12 (11): 1942. http://doi.org/10.3390/antiox12111942.; Chen Y., Cai J., Liu D., et al. Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing. Regen Biomater. 2022; 9: rbac019. http://doi.org/10.1093/rb/rbac019.; Guo J., He L., Li T., et al. Antioxidant and anti-inflammatory effects of different zinc sources on diquat-induced oxidant stress in a piglet model. Biomed Res Int. 2020; 2020: 3464068. http://doi.org/10.1155/2020/3464068.; Mei X., Xu D., Xu S., et al. Gastroprotective and antidepressant effects of a new zinc(II)-curcumin complex in rodent models of gastric ulcer and depression induced by stresses. Pharmacol Biochem Behav. 2011; 99 (1): 66–74. http://doi.org/10.1016/j.pbb.2011.04.002.; Mei X., Luo X., Xu S., et al. Gastroprotective effects of a new zinc(II)-curcumin complex against pylorus-ligature-induced gastric ulcer in rats. Chem Biol Interact. 2009; 181 (3): 316–21. http://doi.org/10.1016/j.cbi.2009.06.022.; Bandyopadhyay B., Bandyopadhyay S.K. Protective effect of zinc gluconate on chemically induced gastric ulcer. Indian J Med Res. 1997; 106: 27–32. PMID: 9248212; Chao H.C. Zinc deficiency and therapeutic value of zinc supplementation in pediatric gastrointestinal diseases. Nutrients. 2023; 15 (19): 4093. http://doi.org/10.3390/nu15194093.; Donkin J.J., Turner R.J., Hassan I., Vink R. Substance P in traumatic brain injury. Prog Brain Res. 2007; 161: 97–109. http://doi.org/10.1016/S0079-6123(06)61007-8.; https://www.pharmacoeconomics.ru/jour/article/view/1117

الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/1117
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.279

المؤلفون: I. Yu. Torshin, O. A. Gromova, A. G. Chuchalin, L. A. Mayorova, И. Ю. Торшин, О. А. Громова, А. Г. Чучалин, Л. А. Майорова

المساهمون: The work was supported by the grant of the Russian Science Foundation No. 20-12-00175-p and conducted in “Ivanovo State University of Chemical Technology”, Работа выполнена при поддержке гранта Российского научного фонда № 20-12-00175-п на базе ФГБОУ ВО «Ивановский государственный химико-технологический университет»

المصدر: Neurology, Neuropsychiatry, Psychosomatics; Vol 16, No 6 (2024); 89-96 ; Неврология, нейропсихиатрия, психосоматика; Vol 16, No 6 (2024); 89-96 ; 2310-1342 ; 2074-2711 ; 10.14412/2074-2711-2024-6

مصطلحات موضوعية: питание, multiple organ pathology, nitric oxide homeostasis, folates, vitamin B12, nutraceuticals, nutrition, полиорганная патология, гомеостаз оксида азота, фолаты, витамин В12, нутрицевтики

وصف الملف: application/pdf

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الاتاحة: https://nnp.ima-press.net/nnp/article/view/2423
https://doi.org/10.14412/2074-2711-2024-6-89-96

المؤلفون: I. Yu. Torshin, O. A. Gromova, И. Ю. Торшин, О. А. Громова

المصدر: Meditsinskiy sovet = Medical Council; № 14 (2024); 135-144 ; Медицинский Совет; № 14 (2024); 135-144 ; 2658-5790 ; 2079-701X

مصطلحات موضوعية: фармакология, alopecia, hair growth, nails, hypovitaminosis, D-biotin, pharmacology, алопеция, рост волос, ногти, гиповитаминоз, D-биотин

وصف الملف: application/pdf

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Am J Clin Nutr. 1989;49(1):127–131. https://doi.org/10.1093/ajcn/49.1.127.; Frigg M, Straub OC, Hartmann D. The bioavailability of supplemental biotin in cattle. Int J Vitam Nutr Res. 1993;63(2):122–128. Available at: https://pubmed.ncbi.nlm.nih.gov/8407161/.; Sawamura H, Fukuwatari T, Shibata K. Effects of excess biotin administration on the growth and urinary excretion of water-soluble vitamins in young rats. Biosci Biotechnol Biochem. 2007;71(12):2977–2984. https://doi.org/10.1271/bbb.70381.; Saint Paul LP, Debruyne D, Bernard D, Mock DM, Defer GL Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis. Expert Opin Drug Metab Toxicol. 2016;12(3):327–344. https://doi.org/10.1517/17425255.2016.1136288.; Zempleni J, Mock DM. Bioavailability of biotin given orally to humans in pharmacologic doses. Am J Clin Nutr. 1999;69(3):504–508. https://doi.org/10.1093/ajcn/69.3.504.; Zempleni J, Mock DM. 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الاتاحة: https://www.med-sovet.pro/jour/article/view/8513
https://doi.org/10.21518/ms2024-296

المؤلفون: I. Yu. Torshin, O. A. Gromova, L. A. Maiorova, И. Ю. Торшин, О. А. Громова, Л. А. Майорова

المساهمون: Thе work was supported by the grant of the Russian Science Foundation No. 20-12-00175-p on the base of Ivanovo State University of Chemistry and Technology., Работа выполнена при поддержке гранта Российского научного фонда № 20-12-00175-п на базе ФГБОУ ВО «Ивановский государственный химико-технологический университет».

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: антиоксидантные эффекты, chemoreactome analysis, topological theory of data analysis, assessment of pharmacological properties, antioxidant effects, хемореактомный анализ, топологическая теория анализа данных, оценка фармакологических свойств

وصف الملف: application/pdf

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Dalton Trans. 2009; 18: 3584–9. https://doi.org/10.1039/b904028e.; Verma A., Sharma S., Gupta P.K., et al. Vitamin B12 functionalized layer by layer calcium phosphate nanoparticles: a mucoadhesive and pH responsive carrier for improved oral delivery of insulin. Acta Biomater. 2016; 31: 288–300. https://doi.org/10.1016/j.actbio.2015.12.017.; Temova Rakuša Ž., Roškar R., Hickey N., Geremia S. Vitamin B12 in foods, food supplements, and medicines – a review of its role and properties with a focus on its stability. Molecules. 2022; 28 (1): 240. https://doi.org/10.3390/molecules28010240.; Koseki K., Yoshimura R., Ido K., et al. Determination of vitamin B12 and folate compounds in commercially available edible seaweed products. Front Biosci. 2023; 15 (2): 10. https://doi.org/10.31083/j.fbe1502010.; Lehner S., Boles E. Development of vitamin B12 dependency in Saccharomyces cerevisiae. FEMS Yeast Res. 2023; 23: foad020. https://doi.org/10.1093/femsyr/foad020.; Watanabe F. 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Серия химическая. 2013; 62 (2): 471–9 (на англ. яз). https://doi.org/10.1007/s11172-013-0066-5.; Kharitonova N.V., Maiorova L.A., Koifman O.I. Aggregation behavior of unsubstituted magnesium porphyrazine in monolayers at air–water interface and in Langmuir–Schaefer films. J Porphyrins Phthalocyanines. 2018; 22 (6): 509–20. https://doi.org/10.1142/S1088424618500505.; Maiorova L.A., Kobayashi N., Zyablov S.V., et al. Magnesium porphine supermolecules and two-dimensional nanoaggregates formed using the Langmuir–Schaefer technique. Langmuir. 2018; 34 (31): 9322–9. https://doi.org/10.1021/acs.langmuir.8b00905.; Maiorova L.A., Kobayashi N., Salnikov D.S., et al. Supermolecular nanoentities of vitamin B12 derivative as a link in the evolution of the parent molecules during self-assembly at the air-water interface. Langmuir. 2023; 39 (9): 3246–54. https://doi.org/10.1021/acs.langmuir.2c02964.; Gromova O.A., Maiorova L.A., Salnikov D.S., et al. Vitamin B12 hydrophobic derivative exhibits bioactivity: biomedical and photophysical study. BioNanoSci. 2022; 12: 74–82. https://doi.org/10.1007/s12668-021-00916-4.; Torshin I.Yu., Rudakov K.V. On the procedures of generation of numerical features over partitions of sets of objects in the problem of predicting numerical target variables. Pattern Recogni Image Anal. 2019; 29 (4): 654–67. https://doi.org/10.1134/S1054661819040175.; Torshin I.Yu. The study of the solvability of the genome annotation problem on sets of elementary motifs. Pattern Recognit Image Anal. 2011; 21 (4): 652–62. https://doi.org/10.1134/S1054661811040171.; Torshin I.Yu., Rudakov K.V. On the application of the combinatorial theory of solvability to the analysis of chemographs. Part 1: Fundamentals of modern chemical bonding theory and the concept of the chemograph. Pattern Recognit Image Anal. 2014; 24 (1): 11–23. https://doi.org/10.1134/S1054661814010209.; Torshin I.Yu., Rudakov K.V. 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الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/1014
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.239

المؤلفون: I. Yu. Torshin, O. A. Gromova, I. A. Dereven’kov, L. A. Maiorova, И. Ю. Торшин, О. А. Громова, И. А. Деревеньков, Л. А. Майорова

المساهمون: Thе work was supported by the grant of the Russian Science Foundation No. 20-12-00175-p on the base of Ivanovo State University of Chemistry and Technology., Работа выполнена при поддержке гранта Российского научного фонда № 20-12-00175-п на базе ФГБОУ ВО «Ивановский государственный химико-технологический университет».

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: протеом человека, chemoproteomic analysis, topological theory of data analysis, assessment of pharmacological properties, human proteome, хемопротеомный анализ, топологическая теория анализа данных, оценка фармакологических свойств

وصف الملف: application/pdf

Relation: https://www.pharmacoeconomics.ru/jour/article/view/961/518; Громова О.А., Торшин И.Ю., Гусев Е.И. Синергидные нейропротекторные эффекты тиамина, пиридоксина и цианокобаламина в рамках протеома человека. Фармакокинетика и фармакодинамика. 2017; 1: 40–51.; Торшин И.Ю., Громова О.А., Майорова Л.А. О перспективах применения производных витамина В12 в фармакологии. ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология. 2023; 16 (3): 501–11. https://doi.org/10.17749/2070-4909/farmakoekonomika.2023.198.; Карлюк М.В., Крыгин Ю.Ю., Майорова-Валькова Л.А. и др. Формирование двумерных (M) и трехмерных (V) наноагрегатов замещенного порфирина кобальта в ленгмюровских слоях и пленках Ленгмюра–Шефера. Известия Академии наук. Серия химическая. 2013; 62 (2): 471–9 (на англ. яз). https://doi.org/10.1007/s11172-013-0066-5.; Петровa M.В., Майоровa Л.А., Громова O.A. и др. 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الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/961
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.214

المؤلفون: D. E. Frolova, I. Yu. Torshin, V. V. Rastashansky, M. V. Filimonova, O. A. Gromova, Д. Е. Фролова, И. Ю. Торшин, В. В. Расташанский, М. В. Филимонова, О. А. Громова

المساهمون: Thе work was supported by the grant of the Russian Science Foundation No. 23-21-00154., Работа выполнена при поддержке гранта Российского научного фонда № 23-21-00154.

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: аскорбат лития, Lewis lung carcinoma, LLC, lithium ascorbate, карцинома легких Льюис, КЛЛ

وصف الملف: application/pdf

Relation: https://www.pharmacoeconomics.ru/jour/article/view/1013/535; Гоголева И.В., Громова О.А., Торшин И.Ю. и др. Нейробиологическая роль солей лития. Журнал неврологии и психиатрии им. С.С. Корсакова. 2022; 122 (11): 17–23. https://doi.org/10.17116/jnevro202212211117.; Vidali S., Aminzadeh-Gohari S., Vatrinet R., et al. Lithium and not acetoacetate influences the growth of cells treated with lithium acetoacetate. Int J Mol Sci. 2019; 20 (12): 3104. https://doi.org/10.3390/ijms20123104.; Cousins D.A., Squarcina L., Boumezbeur F., et al. Lithium: past, present, and future. Lancet Psychiatry. 2020; 7 (3): 222–4. https://doi.org/10.1016/S2215-0366(19)30365-7.; Torshin I.Y., Gromova O.A., Ostrenko K.S., et al. Lithium ascorbate as a promising neuroprotector: fundamental and experimental studies of an organic lithium salt. Molecules. 2022; 27 (7): 2253. https://doi.org/10.3390/molecules27072253.; Härtel C., Strunk T., Bucsky P., Schultz C. Effects of vitamin C on intracytoplasmic cytokine production in human whole blood monocytes and lymphocytes. Cytokine. 2004; 27 (4–5): 101–6. https://doi.org/10.1016/j.cyto.2004.02.004.; Cha J., Roomi M.W., Ivanov V., et al. Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice. Int J Oncol. 2013; 42 (1): 55–64. https://doi.org/10.3892/ijo.2012.1712.; Kurbacher C.M., Wagner U., Kolster B., et al. Ascorbic acid (vitamin C) improves the antineoplastic activity of doxorubicin, cisplatin, and paclitaxel in human breast carcinoma cells in vitr. Cancer Lett. 1996; 103 (2): 183–9. https://doi.org/10.1016/0304-3835(96)04212-7.; Mikirova N., Riordan N., Casciari J. Modulation of cytokines in cancer patients by intravenous ascorbate therapy. Med Sci Monit. 2016; 22: 14–25. https://doi.org/10.12659/MSM.895368.; Carr A.C., Cook J. Intravenous vitamin C for cancer therapy – identifying the current gaps in our knowledge. Front Physiol. 2018; 9: 1182. https://doi.org/10.3389/fphys.2018.01182.; Kawano K., Hattori Y., Iwakura H., et al. Adrenal tumor volume in genetically engineered mouse model of neuroblastoma determined by magnetic resonance imaging. Exp Ther Med. 2012; 4 (1): 61–4. https://doi.org/10.3892/etm.2012.564.; Хабриев Р.У. (ред.) Руководство по экспериментальному (доклиническому) изучению новых фармакологических веществ. 2-е изд. М.: Медицина; 2005: 832 с.; Таскаева И.С. Бгатова Н.П., Соли лития в экспериментальной онкологии (обзор литературы). Сибирский научный медицинский журнал. 2019; 39 (5): 12–8. https://doi.org/10.15372/SSMJ20190502.; Erdal E., Ozturk N., Cagatay T., et al. Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells. Int J Cancer. 2005; 115 (6): 903–10. https://doi.org/10.1002/ijc.20972.; Zubčić V., Rinčić N., Kurtović M., et al. GANT61 and lithium chloride inhibit the growth of head and neck cancer cell lines through the regulation of GLI3 processing by GSK3β. Int J Mol Sci. 2020; 21 (17): 6410. https://doi.org/10.3390/ijms21176410.; de Araujo W.M., Robbs B.K., Bastos L.G., et al. PTEN overexpression cooperates with lithium to reduce the malignancy and to increase cell death by apoptosis via PI3K/Akt suppression in colorectal cancer cells. J Cell Biochem. 2016; 117 (2): 458–69. https://doi.org/10.1002/jcb.25294.; Costabile V., Duraturo F., Delrio P., et al. Lithium chloride induces mesenchymal‑to‑epithelial reverting transition in primary colon cancer cell cultures. Int J Oncol. 2015; 46 (5): 1913–23. https://doi.org/10.3892/ijo.2015.2911.; Lee J.H., Kim S.W., Kim J.H., et al. Lithium chloride protects against sepsis-induced skeletal muscle atrophy and cancer cachexia. Cells. 2021; 10 (5): 1017. https://doi.org/10.3390/cells10051017.; https://www.pharmacoeconomics.ru/jour/article/view/1013

الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/1013
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.236

المؤلفون: А. N. Rubashkina, I. Yu. Torshin, O. A. Gromova, A. N. Galustyan, А. Н. Рубашкина, И. Ю. Торшин, О. А. Громова, А. Н. Галустян

المساهمون: Thе work was supported by the grant of the Russian Science Foundation (Project No. 23-21-00154)., Работа выполнена при поддержке гранта Российского научного фонда (проект № 23-21-00154).

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: транскриптомика, lignans, pathogenetic therapy, pharmacoinformatics, human proteome, transcriptomics, лигнаны, патогенетическая терапия, фармакоинформатика, протеом человека

وصف الملف: application/pdf

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الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/1012
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.240

المؤلفون: O. A. Gromova, D. E. Frolova, I. Yu. Torshin, M. V. Filimonova, M. A. Sorokina, I. A. Reyer, O. A. Limanova, L. E. Fedotova, L. A. Maiorova, О. А. Громова, Д. Е. Фролова, И. Ю. Торшин, М. В. Филимонова, М. А. Сорокина, И. А. Рейер, O. А. Лиманова, Л. Э. Федотова, Л. А. Майорова

المساهمون: Thе work was supported by the grant of the Russian Science Foundation No. 20-12-00175-p on the base of Ivanovo State University of Chemistry and Technology., Работа выполнена при поддержке гранта Российского научного фонда № 20-12-00175-п на базе ФГБОУ ВО «Ивановский государственный химико-технологический университет».

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: экспериментальная фармакология, cell models, vitamin B12, systems biology, bioinformatics, experimental pharmacology, клеточные модели, витамин В12, системная биология, биоинформатика

وصف الملف: application/pdf

Relation: https://www.pharmacoeconomics.ru/jour/article/view/989/522; Volkov I. The master key effect of vitamin B12 in treatment of malignancy – a potential therapy? Med Hypotheses. 2008; 70 (2): 324–8. https://doi.org/10.1016/j.mehy.2007.05.029.; Hernandez B.Y., McDuffie K., Wilkens L.R., et al. Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12. Cancer Causes Control. 2003; 14 (9): 859–70. https://doi.org/10.1023/b:caco.0000003841.54413.98.; Wu K., Helzlsouer K.J., Comstock G.W., et al. A prospective study on folate, B12, and pyridoxal 5'-phosphate (B6) and breast cancer. Cancer Epidemiol Biomarkers Prev. 1999; 8 (3): 209–17.; Nakagawa K., Kudoh S., Matsui K., et al. A phase I study of pemetrexed (LY231514) supplemented with folate and vitamin B12 in Japanese patients with solid tumours. Br J Cancer. 2006; 95 (6): 677–82. https://doi.org/10.1038/sj.bjc.6603321.; Громова О.А., Торшин И.Ю., Гусев Е.И. 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Colloid J. 2008; 70: 6–11. https://doi.org/10.1134/S1061933X0801002X.; Maiorova L.A., Kobayashi N., Salnikov D.S., et al. Supermolecular nanoentities of vitamin B12 derivative as a link in the evolution of the parent molecules during self-assembly at the air-water interface. Langmuir. 2023; 39 (9): 3246–54. https://doi.org/10.1021/acs.langmuir.2c02964.; Dereven’kov I.A., Maiorova L.A., Koifman O.I., Salnikov D.S. High reactivity of supermolecular nanoentities of a vitamin B 12 derivative in Langmuir–Schaefer films toward gaseous toxins. Langmuir. 2023; 39 (48): 17240–50. https://doi.org/10.1021/acs.langmuir.3c02317.; Егоров Е.Е., Терехов С.М., Вишнякова X.С. и др. Теломеризация – способ получения иммортальных клеток человека, сохраняющих нормальные свойства. Онтогенез. 2003; 34 (3): 183–92.; https://www.pharmacoeconomics.ru/jour/article/view/989

الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/989
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.231

المؤلفون: P. A. Galenko-Yaroshevsky, I. Yu. Torshin, A. N. Gromov, O. A. Gromova, R. A. Murashko, A. V. Zelenskaya, L. O. Alukhanyan, O. V. Shelemekh, П. А. Галенко-Ярошевский, И. Ю. Торшин, А. Н. Громов, О. А. Громова, Р. А. Мурашко, А. В. Зеленская, Л. О. Алуханян, О. В. Шелемех

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Vol 17, No 1 (2024); 48-61 ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Vol 17, No 1 (2024); 48-61 ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: интеллектуальный анализ данных, zinc-containing compounds, chemoinformatics, pharmacoinformatics, side effects, data mining, цинк-содержащие соединения, хемоинформатика, фармакоинформатика, побочные эффекты

وصف الملف: application/pdf

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Evaluation of antiinflammatory and ulcerogenic potential of zinc-ibuprofen and zincnaproxen complexes in rats. Inflammopharmacology. 2017; 25 (6): 653–63. https://doi.org/10.1007/s10787-017-0361-0.; Gaweł M., Lipkowska A., Herman M., et al. Chronic treatment with zinc hydroaspartate induces anti-inflammatory and anti-ulcerogenic activity in rats. Pharmacol Rep. 2014; 66 (5): 862–6. https://doi.org/10.1016/j.pharep.2014.05.007.; Торшин И.Ю., Громова О.А. Экспертный анализ данных в молекулярной фармакологии. М.: МЦНМО; 2012: 687 с.; Торшин И.Ю., Громова О.А., Чучалин А.Г., Журавлев Ю.И. Хемореактомный скрининг воздействия фармакологических препаратов на SARS-CoV-2 и виром человека как информационная основа для принятия решений по фармакотерапии COVID-19. ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология. 2021; 14 (2): 191–211. https://doi.org/10.17749/2070-4909/farmakoekonomika.2021.078.; Торшин И.Ю., Громова О.А., Федотова Л.Э., Громов А.Н. Сравнительный хемореактомный анализ декскетопрофена, кетопрофена и диклофенака. Неврология, нейропсихиатрия, психосоматика. 2018; 10 (1): 47–54. http://doi.org/10.14412/2074-2711-2018-1-47-54.; Торшин И.Ю., Громова О.А., Стаховская Л.В., Семёнов В.А. Хемореактомный анализ молекул толперизона, тизанидина и баклофена: холинолитические, спазмолитические и анальгетические механизмы действия. Неврология, нейропсихиатрия, психосоматика. 2018; 10 (4): 72–80. https://doi.org/10.14412/2074-2711-20184-72-80.; Торшин И.Ю. О задачах оптимизации, возникающих при применении топологического анализа данных к поиску алгоритмов прогнозирования с фиксированными корректорами. Информатика и еe применения. 2023; 17 (2): 2–10. https://doi.org/10.14357/19922264230201.; Torshin I.Yu. Sensing the change: from molecular genetics to personalized medicine (bioinformatics in the post-genomic era). 1st ed. NY: Nova Biomedical Books; 2009: 366 pp.; Громова О.А., Торшин И.Ю. Микронутриенты и репродуктивное здоровье. 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Корсакова. 2017; 117 (7): 112–9. https://doi.org/10.17116/jnevro201711771112-119.; Громова О.А., Торшин И.Ю. Важность цинка для поддержания активности белков врожденного противовирусного иммунитета: анализ публикаций, посвященных COVID-19. Профилактическая медицина. 2020; 23 (3): 131–9. https://doi.org/10.17116/profmed202023031131.; Prasad A.S. Zinc is an antioxidant and anti-inflammatory agent: its role in human health. Front Nutr. 2014; 1: 14. https://doi.org/10.3389/fnut.2014.00014.; Громова О.А., Торшин И.Ю., Моисеев В.С. и др. Об использовании цинка и витамина С для профилактики и адъювантной терапии острых респираторных заболеваний. Терапия. 2017; 1 (11): 36–46.; Briassoulis G., Briassoulis P., Ilia S., et al. The Anti-oxidative, antiinflammatory, anti-apoptotic, and anti-necroptotic role of zinc in COVID-19 and sepsis. Antioxidants. 2023; 12 (11): 1942. https://doi.org/10.3390/antiox12111942.; Gaweł M., Librowski T., Lipkowska A. Influence of zinc hydroaspartate on the anti-inflammatory and gastric activity of ketoprofen in rats. Pharmacol Rep. 2013; 65 (1): 214–9. https://doi.org/10.1016/s1734-1140(13)70981-2.; Hessam S., Sand M., Meier N.M., et al. Combination of oral zinc gluconate and topical triclosan: an anti-inflammatory treatment modality for initial hidradenitis suppurativa. J Dermatol Sci. 2016; 84 (2): 197– 202. https://doi.org/10.1016/j.jdermsci.2016.08.010.; Chen Y., Cai J., Liu D., et al. Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing. Regen Biomater. 2022; 9: rbac019. https://doi.org/10.1093/rb/rbac019.; Guo J., He L., Li T., et al. Antioxidant and anti-inflammatory effects of different zinc sources on diquat-induced oxidant stress in a piglet model. Biomed Res Int. 2020; 2020: 3464068. https://doi.org/10.1155/2020/3464068.; Mei X., Xu D., Xu S., et al. Gastroprotective and antidepressant effects of a new zinc(II)-curcumin complex in rodent models of gastric ulcer and depression induced by stresses. Pharmacol Biochem Behav. 2011; 99 (1): 66–74. https://doi.org/10.1016/j.pbb.2011.04.002.; Mei X., Luo X., Xu S., et al. Gastroprotective effects of a new zinc(II)-curcumin complex against pylorus-ligature-induced gastric ulcer in rats. Chem Biol Interact. 2009; 181 (3): 316–21. https://doi.org/10.1016/j.cbi.2009.06.022.; Bandyopadhyay B., Bandyopadhyay S.K. Protective effect of zinc gluconate on chemically induced gastric ulcer. Indian J Med Res. 1997; 106: 27–32.; Golbabapour S., Gwaram N.S., Hassandarvish P., et al. Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats. PLoS One. 2013; 8 (9): e75036. https://doi.org/10.1371/journal.pone.0075036.; Yu C., Mei X.T., Zheng Y.P., Xu D.H. Gastroprotective effect of taurine zinc solid dispersions against absolute ethanol-induced gastric lesions is mediated by enhancement of antioxidant activity and endogenous PGE2 production and attenuation of NO production. Eur J Pharmacol. 2014; 740: 329–36. https://doi.org/10.1016/j.ejphar.2014.07.014.; Rainsford K.D., Whitehouse M.W. Anti-ulcer activity of a slow-release zinc complex, zinc monoglycerolate (Glyzinc). J Pharm Pharmacol. 1992; 44 (6): 476–82. https://doi.org/10.1111/j.2042-7158.1992.tb03650.x.; Chao H.C. Zinc deficiency and therapeutic value of zinc supplementation in pediatric gastrointestinal diseases. Nutrients. 2023; 15 (19): 4093. https://doi.org/10.3390/nu15194093.; Bulbena O., Escolar G., Navarro C., et al. Gastroprotective effect of zinc acexamate against damage induced by nonsteroidal anti- inflammatory drugs. A morphological study. Dig Dis Sci. 1993; 38 (4): 730–9. https://doi.org/10.1007/BF01316807.; Donkin J.J., Turner R.J., Hassan I., Vink R. Substance P in traumatic brain injury. Prog Brain Res. 2007; 161: 97–109. https://doi.org/10.1016/S0079-6123(06)61007-8.; https://www.pharmacoeconomics.ru/jour/article/view/971

الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/971
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.238

المؤلفون: I. Yu. Torshin, M. V. Filimonova, O. A. Gromova, L. A. Maiorova, M. A. Sorokina, D. E. Frolova, A. N. Gromov, I. A. Reyer, И. Ю. Торшин, М. В. Филимонова, О. А. Громова, Л. А. Майорова, М. А. Сорокина, Д. Е. Фролова, А. Н. Громов, И. А. Рейер

المساهمون: Thе work was supported by the grant of the Russian Science Foundation No. 20-12-00175-p on the base of Ivanovo State University of Chemistry and Technology, Работа выполнена при поддержке гранта Российского научного фонда № 20-12-00175-п на базе ФГБОУ ВО «Ивановский государственный химико-технологический университет»

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Vol 17, No 1 (2024); 95-105 ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Vol 17, No 1 (2024); 95-105 ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: исследования на клетках в культуре, vitamin B12, topological data analysis, pharmacoinformatics, studies on cells in culture, витамин В12, топологический анализ данных, фармакоинформатика

وصف الملف: application/pdf

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Supermolecular nanoentities of vitamin B12 derivative as a link in the evolution of the parent molecules during self-assembly at the air-water interface. Langmuir. 2023; 39 (9): 3246–54. https://doi.org/10.1021/acs.langmuir.2c02964.; Торшин И.Ю. О задачах оптимизации, возникающих при применении топологического анализа данных к поиску алгоритмов прогнозирования с фиксированными корректорами. Информатика и ее применения. 2023; 17 (2): 2–10. https://doi.org/10.14357/19922264230201.; Торшин И.Ю. О применении топологического подхода к анализу плохо формализуемых задач для построения алгоритмов виртуального скрининга квантово-механических свойств органических молекул. I: Основы проблемно ориентированной теории. Информатика и ее применения. 2022; 16 (1): 39–45. https://doi.org/10.14357/19922264220106.; Торшин И.Ю. О применении топологического подхода к анализу плохо формализуемых задач для построения алгоритмов виртуального скрининга квантово-механических свойств органических молекул. II: Сопоставление формализма с конструктами квантовой механики и экспериментальная апробация предложенных алгоритмов. Информатика и ее применения. 2022; 16 (2): 35–43. https://doi.org/10.14357/19922264220205.; ChEMBL. Genomics of drug sensitity in cancer screening data. URL: http://www.doi.org/10.6019/CHEMBL1201861 (дата обращения 15.08.2023).; Егоров Е.Е., Терехов С.М., Вишнякова К. и др. Теломеризация как метод получения бессмертных клеток человека, сохраняющих нормальные свойства. Ontogenez. 2003; 34 (3): 183–92.; Шадрин В.С., Кожин П.М., Шошина О.О. и др. Теломеризованные фибробласты как потенциальный объект для 3D-моделирования патологических гипертрофических рубцов in vitro. Вестник Российского государственного медицинского университета. 2020; 5: 82–90. https://doi.org/10.24075/vrgmu.2020.057.; https://www.pharmacoeconomics.ru/jour/article/view/921

الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/921
https://doi.org/10.17749/2070-4909/farmakoekonomika.2023.209

المؤلفون: I. Yu. Torshin, O. A. Gromova, И. Ю. Торшин, О. А. Громова

المساهمون: The research was conducted under the government contract No. 0063-2019-0003 “Mathematical methods of data analysis and forecasting” using the infrastructure of the Shared Research Facilities “High Performance Computing and Big Data” (SRF “Informatics”), of FRC “Computer Science and Control”, RAS (Moscow), Работа выполнялась по государственному заданию № 0063-2019-0003 «Математические методы анализа данных и прогнозирования» с использованием инфраструктуры Центра коллективного пользования «Высокопроизводительные вычисления и большие данные» (ЦКП «Информатика») ФИЦ «Информатика и управление» РАН (г. Москва)

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Online First ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Online First ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: нейропротекторы, parabens, toxicity, pharmaceutical preservatives, chondroprotectors, neuroprotectors, парабены, токсичность, фармацевтические консерванты, хондропротекторы

وصف الملف: application/pdf

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الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/1030
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.263

المؤلفون: O. A. Gromova, I. Yu. Torshin, О. А. Громова, И. Ю. Торшин

المساهمون: The research was conducted using the infrastructure of the Shared Research Facilities "High Performance Computing and Big Data" (CKP "Informatics"), FRC “Computer Science and Control”, RAS (Moscow)., Работа выполнена с использованием инфраструктуры Центра коллективного пользования «Высокопроизводительные вычисления и большие данные» (ЦКП «Информатика») ФИЦ «Информатика и управление» РАН (г. Москва).

المصدر: FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology; Vol 17, No 2 (2024); 172-181 ; ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология; Vol 17, No 2 (2024); 172-181 ; 2070-4933 ; 2070-4909

مصطلحات موضوعية: топологический анализ данных, fonturacetam, nootropics, racetams, obesity, pharmacoinformatics, topological data analysis, фонтурацетам, ноотропы, рацетамы, ожирение, фармакоинформатика

وصف الملف: application/pdf

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الاتاحة: https://www.pharmacoeconomics.ru/jour/article/view/1033
https://doi.org/10.17749/2070-4909/farmakoekonomika.2024.260

المؤلفون: T. E. Bogacheva, O. A. Gromova, I. Yu. Torshin, Т. Е. Богачева, О. А. Громова, И. Ю. Торшин

المصدر: Pharmacokinetics and Pharmacodynamics; № 1 (2024); 4-13 ; Фармакокинетика и Фармакодинамика; № 1 (2024); 4-13 ; 2686-8830 ; 2587-7836

مصطلحات موضوعية: метаболизм, D-chiro inositol, hepatoprotection, neurocytology, neuroprotection, steatohepatitis, metabolism, D-хироинозитол, гепатопротекция, нейроцитология, нейропротекция, стеатогепатит

وصف الملف: application/pdf

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الاتاحة: https://www.pharmacokinetica.ru/jour/article/view/405
https://doi.org/10.37489/2587-7836-2024-1-4-13

المؤلفون: А. N. Rubashkina, I. Yu. Torshin, O. A. Gromova, А. Н. Рубашкина, И. Ю. Торшин, О. А. Громова

المساهمون: This work was supported by a grant from the Russian Science Foundation (project № 23-21-00154)., Работа выполнена по гранту Российского научного фонда (проект № 23-21-00154).

المصدر: Pharmacokinetics and Pharmacodynamics; № 1 (2024); 66-76 ; Фармакокинетика и Фармакодинамика; № 1 (2024); 66-76 ; 2686-8830 ; 2587-7836

مصطلحات موضوعية: транскриптомика, lignans, pathogenetic therapy, pharmacoinformatics, human proteome, transcriptomics, лигнаны, патогенетическая терапия, фармакоинформатика, протеом человека

وصف الملف: application/pdf

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الاتاحة: https://www.pharmacokinetica.ru/jour/article/view/411
https://doi.org/10.37489/2587-7836-2024-1-66-76

المؤلفون: T. E. Bogacheva, I. Yu. Torshin, O. A. Gromova, Т. Е. Богачева, И. Ю. Торшин, О. А. Громова

المصدر: Pharmacokinetics and Pharmacodynamics; № 4 (2023); 3-14 ; Фармакокинетика и Фармакодинамика; № 4 (2023); 3-14 ; 2686-8830 ; 2587-7836

مصطلحات موضوعية: протеомные исследования, Laennec, analysis of publications, liver diseases, regeneration, proteomic studies, Лаеннек, анализ публикаций, болезни печени, регенерация

وصف الملف: application/pdf

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الاتاحة: https://www.pharmacokinetica.ru/jour/article/view/387
https://doi.org/10.37489/2587-7836-2023-4-3-14

المؤلفون: I. Yu. Torshin, T. E. Bogacheva, O. A. Gromova, И. Ю. Торшин, Т. Е. Богачева, О. А. Громова

المصدر: Pharmacokinetics and Pharmacodynamics; № 4 (2023); 15-22 ; Фармакокинетика и Фармакодинамика; № 4 (2023); 15-22 ; 2686-8830 ; 2587-7836

مصطلحات موضوعية: антибактериальный эффект, antibacterial effect

وصف الملف: application/pdf

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DOI:10.1016/j.bbrc.2016.01.037.; https://www.pharmacokinetica.ru/jour/article/view/388

الاتاحة: https://www.pharmacokinetica.ru/jour/article/view/388
https://doi.org/10.37489/2587-7836-2023-4-15-22