المؤلفون: A. V. Pak, E. A. Pashkov, N. D. Abramova, A. V. Poddubikov, F. G. Nagieva, E. A. Bogdanova, E. P. Pashkov, O. A. Svitich, V. V. Zverev, А. В. Пак, Е. А. Пашков, Н. Д. Абрамова, А. В. Поддубиков, Ф. Г. Нагиева, Е. А. Богданова, Е. П. Пашков, О. А. Свитич, В. В. Зверев

المساهمون: The study was carried out using the scientific equipment of the Center for Collective Use of the I. Mechnikov Research Institute of Vaccines and Sera, and supported by the Ministry of Science and Higher Education of the Russian Federation, Agreement No. 075-15-2021-676 dated July 28, 2021., Исследование выполнено с использованием научного оборудования Центра коллективного пользования Научно-исследовательского института вакцин и сывороток им. И.И. Мечникова Министерства здравоохранения Российской Федерации при финансовой поддержке Министерства науки и высшего образования Российской Федерации, соглашение № 075-15-2021-676 от 28.07.2021.

المصدر: Fine Chemical Technologies; Vol 17, No 5 (2022); 384-393 ; Тонкие химические технологии; Vol 17, No 5 (2022); 384-393 ; 2686-7575 ; 2410-6593

مصطلحات موضوعية: вирусная РНК, IL-1β, influenza A virus, IFN-λ3, gene expression, siRNA, pro-inflammatory cytokines, IL-28β, viral RNA, вирус гриппа А, экспрессия генов, миРНК, провоспалительные цитокины

وصف الملف: application/pdf

Relation: https://www.finechem-mirea.ru/jour/article/view/1880/1875; https://www.finechem-mirea.ru/jour/article/view/1880/1876; https://www.finechem-mirea.ru/jour/article/downloadSuppFile/1880/728; Пашков Е.А., Коротышева М.О., Пак А.В., Файзулоев Е.Б., Сидоров А.В., Поддубиков А.В., Быстрицкая Е.П., Дронина Ю.Е., Солнцева В.К., Зайцева Т.А., Пашков Е.П., Быков А.С., Свитич О.А., Зверев В.В. Исследование противогриппозной активности комплексов миРНК против клеточных генов FLT4, Nup98 и Nup205 на модели in vitro. Тонкие химические технологии. 2022;17(2):140–151. https://doi.org/10.32362/2410-6593-2022-17-2-140-151; Пашков Е.А., Файзулоев Е.Б., Корчевая Е.Р., Ртищев А.А., Черепович Б.С., Сидоров А.В., Поддубиков А.В., Быстрицкая Е.П., Дронина Ю.Е., Быков А.С., Свитич О.А., Зверев В.В. Нокдаун клеточных генов FLT4, Nup98 и Nup205 как супрессор вирусной активности гриппа А/WSN/33 (H1N1) в культуре клеток А549. 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الاتاحة: https://www.finechem-mirea.ru/jour/article/view/1880
https://doi.org/10.32362/2410-6593-2022-17-5-384-393

المؤلفون: E. A. Pashkov, M. O. Korotysheva, A. V. Pak, E. B. Faizuloev, A. V. Sidorov, A. V. Poddubikov, E. P. Bystritskaya, Yu. E. Dronina, V. K. Solntseva, T. A. Zaiceva, E. P. Pashkov, A. S. Bykov, O. A. Svitich, V. V. Zverev, Е. А. Пашков, М. О. Коротышева, А. В. Пак, Е. Б. Файзулоев, А. В. Сидоров, А. В. Поддубиков, Е. П. Быстрицкая, Ю. Е. Дронина, В. К. Солнцева, Т. А. Зайцева, Е. П. Пашков, А. С. Быков, О. А. Свитич, В. В. Зверев

المساهمون: The authors are grateful to the Center for Collective Use of the I.I. Mechnikov Research Institute of Vaccines and Sera., Авторы выражают благодарность центру коллективного пользования НИИВС им И.И. Мечникова.

المصدر: Fine Chemical Technologies; Vol 17, No 2 (2022); 140-151 ; Тонкие химические технологии; Vol 17, No 2 (2022); 140-151 ; 2686-7575 ; 2410-6593

مصطلحات موضوعية: вирусная РНК, influenza A virus, gene expression, mRNA, small interfering RNA, viral RNA, вирус гриппа А, экспрессия генов, матричная РНК, малые интерферирующие РНК

وصف الملف: application/pdf

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Нокдаун клеточных генов FLT4, Nup98 и Nup205 как супрессор вирусной активности гриппа А/WSN/33 (H1N1) в культуре клеток А549. Тонкие химические технологии. 2021;16(6):476–489. https://doi.org/10.32362/2410-6593-2021-16-6-476-489; Пашков Е.А., Корчевая Е.Р., Файзулоев Е.Б., Пашков Е.П., Зайцева Т.А., Ртищев А.А., Поддубиков А.В., Свитич О.А., Зверев В.В., Создание модели изучения противовирусного действия малых интерферирующих РНК in vitro. Санитарный врач. 2022;1. https://doi.org/10.33920/med-08-2201-07; Lee H.K, Loh T.P., Lee C.K., Tang J.W., Chiu L., Koay E.S. A universal influenza A and B duplex real-time RT-PCR assay. J. Med. Virol. 2012;84(10):1646–1651. https://doi.org/10.1002/jmv.23375; Ramakrishnan M.A. Determination of 50% endpoint titer using a simple formula. World J. Virol. 2016;5(2):85–86. https://doi.org/10.5501/wjv.v5.i2.85; Estrin M.A., Hussein I.T.M., Puryear W.B., Kuan A.C., Artim S.C., Runstadler J.A. Host-directed combinatorial RNAi improves inhibition of diverse strains of influenza A virus in human respiratory epithelial cells. PLoS One. 2018;13(5):e0197246. https://doi.org/10.1371/journal.pone.0197246; Piasecka J., Lenartowicz E., Soszynska-Jozwiak M., Szutkowska B., Kierzek R., Kierzek E. RNA Secondary Structure Motifs of the Influenza A Virus as Targets for siRNA-Mediated RNA Interference. Mol. Ther. Nucleic Acids. 2020;19:627–642. https://doi.org/10.1016/j.omtn.2019.12.018; https://www.finechem-mirea.ru/jour/article/view/1822

الاتاحة: https://www.finechem-mirea.ru/jour/article/view/1822
https://doi.org/10.32362/2410-6593-2022-17-2-140-151