المؤلفون: Ren-Wang Jiang, Wei Xu, Mu Yuan

المصدر: Journal of Molecular Structure. 1130:895-900

مصطلحات موضوعية: 0301 basic medicine, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, Quinoline, Antagonist, Crystal structure, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, Analytical Chemistry, Inorganic Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Docking (molecular), α1a adrenoceptor, Prazosin, medicine, Selectivity, Spectroscopy, Biological evaluation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7b3f24f6c5e6afaab83151f548a26cc6
https://doi.org/10.1016/j.molstruc.2016.10.084

المؤلفون: Kazuyasu Maruyama, Mamoru Kobayashi, Saori Yonekubo, Satoshi Tatemichi, Kumi Tsuchioka

المصدر: Pharmacology. 95:285-292

مصطلحات موضوعية: Male, medicine.medical_specialty, Indoles, medicine.drug_class, medicine.medical_treatment, Urination, Pyridinium Compounds, urologic and male genital diseases, Bladder outlet obstruction, Urine flow rate, Internal medicine, Diabetes Mellitus, medicine, Animals, Obesity, Saline, Pharmacology, Distigmine, business.industry, Antagonist, General Medicine, Silodosin, female genital diseases and pregnancy complications, Rats, Zucker, Endocrinology, Acetylcholinesterase inhibitor, α1a adrenoceptor, Adrenergic alpha-1 Receptor Antagonists, Cholinesterase Inhibitors, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38d5a7754f78088ea4d559343b69515
https://doi.org/10.1159/000398811

المؤلفون: Hiroki Kumagai, Masafumi Isogaya, Mitsuhiro Moriwaki, Ryoji Hayashi, Eiji Ohmori

المصدر: Bioorganic & Medicinal Chemistry Letters. 25:3921-3923

مصطلحات موضوعية: Indoles, Dose-Response Relationship, Drug, Molecular Structure, Adrenergic receptor, Chemistry, Organic Chemistry, Clinical Biochemistry, Antagonist, Pharmaceutical Science, Pharmacology, Biochemistry, In vitro binding, Rats, Substrate Specificity, Structure-Activity Relationship, Piperidines, α1a adrenoceptor, Receptors, Adrenergic, alpha-1, Indolylpiperidine, α1b adrenoceptor, Drug Discovery, Adrenergic alpha-1 Receptor Antagonists, Animals, Molecular Medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598a6db7f0a2feec9be133f477821f33
https://doi.org/10.1016/j.bmcl.2015.07.046

المؤلفون: James R. Docherty

المصدر: Autonomic and Autacoid Pharmacology. 33:49-57

مصطلحات موضوعية: Male, medicine.medical_specialty, Adrenergic receptor, In Vitro Techniques, Pharmacology, Piperazines, α1d adrenoceptor, Norepinephrine, Vas Deferens, Cocaine, Receptors, Adrenergic, alpha-1, Internal medicine, medicine, Prazosin, Animals, Potency, Drug Interactions, Receptor, Adrenergic Uptake Inhibitors, Dose-Response Relationship, Drug, Chemistry, Antagonist, Vas deferens, Rats, medicine.anatomical_structure, Endocrinology, α1a adrenoceptor, Adrenergic alpha-1 Receptor Antagonists, Thymine, Muscle Contraction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8611b019dc33267b4f690e445c666a1
https://doi.org/10.1111/aap.12015

المؤلفون: Bunya Kawamoto, Katsuya Hikita, Masashi Honda, Motoaki Saito, Kuniyasu Muraoka, Youichirou Higashi, Takahiro Shimizu, Atsushi Takenaka, Shogo Shimizu

المصدر: Journal of Urology. 195

مصطلحات موضوعية: medicine.medical_specialty, Urinary bladder, Cyclophosphamide, business.industry, Urology, Rat model, Interstitial cystitis, Silodosin, medicine.disease, medicine.anatomical_structure, α1a adrenoceptor, medicine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d7fd304769431f0e3a6e53c133c820ed
https://doi.org/10.1016/j.juro.2016.02.1054

المؤلفون: Lee R. Roberts, null et al.

المصدر: ChemInform. 47

مصطلحات موضوعية: chemistry, α1a adrenoceptor, chemistry.chemical_element, General Medicine, Carbonylation, Combinatorial chemistry, Partial agonist, Catalysis, Rhodium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4274c262a0474aa32ac67f8082c46962
https://doi.org/10.1002/chin.201612118

المؤلفون: Gary Hoel, Weining Volinn, Lawrence A. Hill, Marc Gittelman, Leonard S. Marks

المصدر: Journal of Urology. 181:2634-2640

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Indoles, Time Factors, Urology, Prostatic Hyperplasia, Signs and symptoms, Placebo, law.invention, Randomized controlled trial, Double-Blind Method, law, Clinical endpoint, medicine, Humans, Adverse effect, Aged, Aged, 80 and over, business.industry, Antagonist, Middle Aged, Silodosin, Hyperplasia, medicine.disease, Highly selective, Surgery, Clinical trial, α1a adrenoceptor, Adrenergic alpha-1 Receptor Antagonists, International Prostate Symptom Score, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00962a5c1ae639fba6a603fb2f95cff
https://doi.org/10.1016/j.juro.2009.02.034

المؤلفون: Fumiko Suzuki, Ikunobu Muramatsu, A S Md Anisuzzaman, Shigeru Morishima, Takashi Tanaka, Hatsumi Yoshiki, Zakia Sultana Sathi

المصدر: British Journal of Pharmacology. 153:1485-1494

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Chemistry, Central nervous system, Antagonist, α1l adrenoceptor, Radioligand Assay, Endocrinology, medicine.anatomical_structure, Cerebral cortex, α1a adrenoceptor, Internal medicine, medicine, Prazosin, Binding site, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::22bd9b7fba21c7d4436c314527d8b159
https://doi.org/10.1038/sj.bjp.0707679

المؤلفون: Keiji Inoue, Panagiota Tsounapi, Youichirou Higashi, Motoaki Saito, Takahiro Shimizu, Shogo Shimizu, Felix Holmström, Masashi Honda, Kumiko Nakamura

المصدر: Journal of Urology. 193

مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Spontaneously hypertensive rat, business.industry, α1a adrenoceptor, Urology, Internal medicine, medicine, Blood flow, Silodosin, business, Prostatic enlargement, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2cda92dcbc4943a9e506aa1c0be33dc8
https://doi.org/10.1016/j.juro.2015.02.1357

المؤلفون: Jutta L. Miller, Thomas Marbury, Gregory A. Winchell, Keith Gottesdiener, G. Mistry, John A. Wagner, Prasad P. Kari, Richard C. Simpson, A. David Rodrigues

المصدر: The Journal of Clinical Pharmacology. 45:699-703

مصطلحات موضوعية: Adult, Male, Administration, Oral, Pyrimidinones, Pharmacology, Drug Administration Schedule, Cytochrome P-450 Enzyme System, Double-Blind Method, Theophylline, Pharmacokinetics, Coumarins, Sulfaphenazole, Receptors, Adrenergic, alpha-1, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme Inhibitors, Humans, Medicine, Pharmacology (medical), Carbon Radioisotopes, Fomepizole, Cross-Over Studies, business.industry, Antagonist, Quinidine, Ketoconazole, α1a adrenoceptor, Area Under Curve, Adrenergic alpha-1 Receptor Antagonists, Microsomes, Liver, Pyrazoles, Drug Therapy, Combination, business, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0962662fb267351faf0b3ec5f9ae780
https://doi.org/10.1177/0091270005275289

المؤلفون: Minyong Li, Keng-Chang Tsai, Lin Xia

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:657-664

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Expert Systems, Biochemistry, Structure-Activity Relationship, Receptors, Adrenergic, alpha-1, Drug Discovery, Feature based, Humans, Structure–activity relationship, Molecular Biology, Adrenergic alpha-Antagonists, Virtual screening, Chemistry, Organic Chemistry, Biological activity, Software package, Combinatorial chemistry, α1a adrenoceptor, Adrenergic alpha-1 Receptor Antagonists, Molecular Medicine, Pharmacophore, Software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0a6c89e04e3efec6be589c0ce7230a
https://doi.org/10.1016/j.bmcl.2004.11.032

المؤلفون: Miao Shou Wu, Stacey O'Malley, Kamlesh P. Vyas, Paul J. Kling, Raymond S.L. Chang, Wanying Sun, Wai C. Wong, Richard W. Ransom, Kanyin Zhang, John M. Wetzel, Jian Peng, Charles Gluchowski, Theodore P. Broten, Dhanapalan Nagarathnam, Carlos Forray, Fengqi Zhang, Dake Tian, Bharat Lagu, Tsing B. Chen, Mohammad R. Marzabadi

المصدر: Journal of Medicinal Chemistry. 42:4804-4813

مصطلحات موضوعية: Male, medicine.drug_class, Stereochemistry, Drug Evaluation, Preclinical, Administration, Oral, Biological Availability, Carboxamide, In Vitro Techniques, Binding, Competitive, Chemical synthesis, Structure-Activity Relationship, Dogs, Smooth muscle, Receptors, Adrenergic, alpha-1, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Adrenergic alpha-Antagonists, Chemistry, Prostate, Antagonist, Stereoisomerism, Recombinant Proteins, Rats, Pyrimidines, α1a adrenoceptor, Drug Design, Benzene derivatives, Adrenergic alpha-1 Receptor Antagonists, Molecular Medicine, Enantiomer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644bb1e845f3476e1d3846442d956b07
https://doi.org/10.1021/jm9902032

المؤلفون: Richard P. Burt, Christopher R. Chapple, Ian W. Marshall

المصدر: European Urology. 36:42-47

مصطلحات موضوعية: medicine.medical_specialty, Phospholipase C, business.industry, Urology, behavioral disciplines and activities, Human prostate, Cell biology, Endocrinology, α1a adrenoceptor, Internal medicine, Alpha1 adrenoceptor, Medicine, Signal transduction, business, Protein kinase C, Diacylglycerol kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::906058fc8df603a82b19b43af0e3799f
https://doi.org/10.1159/000052317

المؤلفون: James R. Docherty

المصدر: The FASEB Journal. 27

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Vas deferens, α1l adrenoceptor, Biochemistry, Endocrinology, medicine.anatomical_structure, α1a adrenoceptor, Internal medicine, Genetics, medicine, business, Molecular Biology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5dcaf9688a7654eeb2d66ad4007e8723
https://doi.org/10.1096/fasebj.27.1_supplement.1096.15

المؤلفون: Katsuyoshi Akiyama, Imao Mikoshiba, Junzo Kudoh, Masaki Yoshida

المصدر: Case Studies in Modern Drug Discovery and Development

مصطلحات موضوعية: medicine.medical_specialty, business.industry, α1a adrenoceptor, Urology, Antagonist, Medicine, Silodosin, Hyperplasia, business, medicine.disease, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::663f6af96f9efae4ff07f5eb979f697e
https://doi.org/10.1002/9781118219683.ch14

المؤلفون: Lei Meng, Yuwang Liu, Ying Zhou, Peihong Sun, Xia Zhao, Yimin Cui

المصدر: Biologicalpharmaceutical bulletin. 34(8)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adrenergic Antagonists, Indoles, Urology, Pharmaceutical Science, Selective antagonist, Pharmacology, law.invention, Young Adult, Randomized controlled trial, Pharmacokinetics, Asian People, Double-Blind Method, law, Receptors, Adrenergic, alpha-1, Adrenergic antagonist, Medicine, Humans, Dosing, Adverse effect, business.industry, Headache, General Medicine, Silodosin, α1a adrenoceptor, Area Under Curve, Vertigo, Hypotension, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77620dc67c750bbef741954a8bcc3c66
https://pubmed.ncbi.nlm.nih.gov/21804212

المؤلفون: Takahiro Yasui, Atsushi Okada, Shoichi Sasaki, Yoshiyuki Kojima, Masahito Hirose, Yasunori Itoh, Keiichi Tozawa, Shuzo Hamamoto, Kenjiro Kohri

المصدر: International Journal of Urology.

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Urology, Antagonist, Ureteral stone, Silodosin, Surgery, α1a adrenoceptor, Male patient, Medicine, Prospective randomized study, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd3498b54daf1f3fbb3d8a1d86634751
https://doi.org/10.1111/j.1442-2042.2011.02810.x

المؤلفون: Mario Matarrese, Rosa Maria Moresco, A. Carpinelli, Giuseppe Romeo, F. Fazio, P. Simonelli, Filippo Russo, Sergio Todde, M. Galli Kienle

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 44:S421-S423

مصطلحات موضوعية: α1a adrenoceptor, In vivo, Chemistry, Organic Chemistry, Drug Discovery, Radioligand, Radiology, Nuclear Medicine and imaging, Pharmacology, Biochemistry, α1 adrenoceptor, Spectroscopy, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4a008dccc6bd28264a70bd0384ef4397
https://doi.org/10.1002/jlcr.25804401149

المؤلفون: Nicolas Gilles, Stefano Palea, Philippe Lluel, Moez Rekik, Pascal Rischmann

المصدر: Journal of Urology. 183

مصطلحات موضوعية: medicine.medical_specialty, Adenoma, business.industry, Urology, medicine.disease, law.invention, Endocrinology, α1a adrenoceptor, law, Tamsulosin, Internal medicine, medicine, Recombinant DNA, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::53d5a61e44ebd0b6d9e373f7acff89a6
https://doi.org/10.1016/j.juro.2010.02.1114

المؤلفون: Anthony P.D.W. Ford, Dinesh Kumar Srinivasan, Jong Moo Kim, Anindya Bhattacharya, Leah R. Burbach

المصدر: The FASEB Journal. 20

مصطلحات موضوعية: Urethra, medicine.anatomical_structure, business.industry, α1a adrenoceptor, Genetics, medicine, Rabbit (nuclear engineering), Anatomy, business, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6b9c039e528238a34ed99163af582d51
https://doi.org/10.1096/fasebj.20.4.a660-c