المؤلفون: Otsile O. Mojanaga, Timothy J. Woodman, Matthew D. Lloyd, K. Ravi Acharya

المصدر: Biomolecules, Vol 14, Iss 3, p 299 (2024)

مصطلحات موضوعية: α-Methylacyl-CoA racemase (AMACR, P504S), CoA-transferase, colorimetric assay, epimerase, fenoprofen, ibuprofen, Microbiology, QR1-502

Relation: https://www.mdpi.com/2218-273X/14/3/299; https://doaj.org/toc/2218-273X; https://doaj.org/article/d66d65e2902d46ff934b3d658be25e44

الاتاحة: https://doi.org/10.3390/biom14030299
https://doaj.org/article/d66d65e2902d46ff934b3d658be25e44

المؤلفون: S. V. Popov, R. G. Guseynov, O. N. Skryabin, I. N. Orlov, A. A. Vorobyov, A. G. Martov, V. L. Shchukin

المصدر: Issledovaniâ i Praktika v Medicine, Vol 6, Iss 1, Pp 41-49 (2019)

مصطلحات موضوعية: prostate cancer, atypical small acinar proliferation, immunohistochemical diagnostics, high molecular weight cytokeratin 34βe12, p63 nuclear protein, α-methylacyl-coa-racemase, Medicine

وصف الملف: electronic resource

Relation: https://www.rpmj.ru/rpmj/article/view/356; https://doaj.org/toc/2410-1893

URL الوصول: https://doaj.org/article/997183da92314201b6c8e9ef53cc9e6e

المؤلفون: Woodman, Tim, Lloyd, Matthew

المساهمون: Lloyd, Matthew

المصدر: Woodman , T & Lloyd , M 2023 , Analysis of enzyme reactions using NMR techniques: A case study with α-methylacyl-CoA racemase (AMACR) . in M Lloyd (ed.) , Modern Methods of Drug Design and Development . Methods in Enzymology , vol. 690 , Elsevier Academic Press Inc , New York, U. S. A. , pp. 159-209 . https://doi.org/10.1016/bs.mie.2023.07.005

مصطلحات موضوعية: Acyl-CoA esters, Chemical synthesis, Colorimetric substrate, Fluorine, Ibuprofen, NMR assays, α-Methylacyl-CoA racemase (AMACR, P504S), /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

Relation: https://researchportal.bath.ac.uk/en/publications/8a8e929f-32e0-4bd0-b2c5-2cacacc8dddb; urn:ISBN:9780443158711

الاتاحة: https://researchportal.bath.ac.uk/en/publications/8a8e929f-32e0-4bd0-b2c5-2cacacc8dddb
https://doi.org/10.1016/bs.mie.2023.07.005
http://www.scopus.com/inward/record.url?scp=85168347975&partnerID=8YFLogxK

المؤلفون: Mojanaga, Otsile, Ravi Acharya, K., Lloyd, Matthew D.

المساهمون: Lloyd, Matthew

المصدر: Mojanaga , O , Ravi Acharya , K & Lloyd , M D 2023 , Recombinant protein production for structural and kinetic studies: A case study using M. tuberculosis α-methylacyl-CoA racemase (MCR) . in M Lloyd (ed.) , Modern Methods of Drug Design and Development . Methods in Enzymology , vol. 690 , Elsevier Academic Press Inc , New York, U. S. A. , pp. 1-37 . https://doi.org/10.1016/bs.mie.2023.07.001

مصطلحات موضوعية: Anion-exchange chromatography, Cation-exchange chromatography, Expression and purification of recombinant proteins, Recombinant E. coli, SDS-PAGE, Size-exclusion chromatography, α-Methylacyl-CoA racemase, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

Relation: https://researchportal.bath.ac.uk/en/publications/20b7c4fa-84f3-4517-aa55-f366f2ac759e; urn:ISBN:9780443158711

الاتاحة: https://researchportal.bath.ac.uk/en/publications/20b7c4fa-84f3-4517-aa55-f366f2ac759e
https://doi.org/10.1016/bs.mie.2023.07.001
http://www.scopus.com/inward/record.url?scp=85168365715&partnerID=8YFLogxK

المؤلفون: Petrova, Yoana, Wadda, Katty, Nathubhai, Amit, Jevglevskis, Maksims, Mitchell, Paul, James, Tony, Threadgill, Michael, Woodman, Tim, Lloyd, Matthew

المصدر: Petrova , Y , Wadda , K , Nathubhai , A , Jevglevskis , M , Mitchell , P , James , T , Threadgill , M , Woodman , T & Lloyd , M 2019 , ' Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships ' , Bioorganic Chemistry , vol. 92 , 103264 . https://doi.org/10.1016/j.bioorg.2019.103264

مصطلحات موضوعية: Branched-chain fatty acids, High-throughput screening, Ibuprofen metabolism, Mixed competitive inhibition, Prostate cancer, Structure-activity relationships, Uncompetitive inhibition, α-Methylacyl-CoA racemase (AMACR P504S), /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1600/1605, name=Organic Chemistry, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

Relation: https://researchportal.bath.ac.uk/en/publications/50580eff-df16-4664-8abe-1943a5de8510

الاتاحة: https://researchportal.bath.ac.uk/en/publications/50580eff-df16-4664-8abe-1943a5de8510
https://doi.org/10.1016/j.bioorg.2019.103264
https://purehost.bath.ac.uk/ws/files/198046338/Paper_7.pdf
https://purehost.bath.ac.uk/ws/files/198046339/Supporting_Information_7.pdf
https://purehost.bath.ac.uk/ws/files/198046340/Spectroscopic_data.pdf
http://www.scopus.com/inward/record.url?scp=85072258773&partnerID=8YFLogxK
https://www.sciencedirect.com/science/article/pii/S0045206819303980?via%3Dihub

المؤلفون: Jevglevskis, Maksims, Lee, Guat Ling, Nathubhai, Amit, Petrova, Yoana, James, Tony, Threadgill, Michael, Woodman, Timothy, Lloyd, Matthew

المصدر: Jevglevskis , M , Lee , G L , Nathubhai , A , Petrova , Y , James , T , Threadgill , M , Woodman , T & Lloyd , M 2018 , ' Structure-activity relationships of rationally designed AMACR 1A inhibitors ' , Bioorganic and Medicinal Chemistry , vol. 79 , pp. 145-154 . https://doi.org/10.1016/j.bioorg.2018.04.024

مصطلحات موضوعية: Drug lipophilicity, Enzyme inhibitors, Rational drug design, Structure-activity relationships, α-Methylacyl-CoA racemase (AMACR, P504S), /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1600/1605, name=Organic Chemistry, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الاتاحة: https://researchportal.bath.ac.uk/en/publications/c248b8b8-deae-4433-96d9-c65410d2b129
https://doi.org/10.1016/j.bioorg.2018.04.024
https://purehost.bath.ac.uk/ws/files/170025975/Revised_manuscript.pdf
http://www.scopus.com/inward/record.url?scp=85046647493&partnerID=8YFLogxK

المؤلفون: Burak Arslan, Ersin Gökmen, Oktay Özman, Serkan Gönültaş, Murat Kars

المصدر: Üroonkoloji Bülteni, Vol 20, Iss 2, Pp 92-95 (2021)

مصطلحات موضوعية: Cultural Studies, Biochemical recurrence, medicine.medical_specialty, Urology, Specialties of internal medicine, Prostate cancer, amacr/p504s, Biopsy, α methylacyl coa racemase, Medicine, Internal medicine, RC254-282, Core (anatomy), medicine.diagnostic_test, business.industry, Religious studies, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, prostate cancer, medicine.disease, RC31-1245, Diseases of the genitourinary system. Urology, psa, RC581-951, RC870-923, business, Intermediate risk

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bb8233c8bd82bdc37d6c8c2f89e1a8
https://doi.org/10.4274/uob.galenos.2020.1721

المؤلفون: Atsuhiko Yoshizawa, Kosuke Fukaya, Kenji Zennami, Masanobu Saruta, Takuhisa Nukaya, Hitomi Sasaki, Makoto Sumitomo, Ryoichi Shiroki, Mamoru Kusaka, Manabu Ichino, Atsuko Niimi, Kiyoshi Takahara, Motoshi Suzuki, Naohiko Fukami

المصدر: Prostate International
Prostate International, Vol 9, Iss 1, Pp 18-24 (2021)

مصطلحات موضوعية: Urology, 030232 urology & nephrology, PCa, prostate cancer, Docetaxel, HSP27, lcsh:RC870-923, urologic and male genital diseases, 03 medical and health sciences, Prostate cancer, HSP27, heat shock protein 27, 0302 clinical medicine, Downregulation and upregulation, Hsp27, FBS, fetal bovine serum, Heat shock protein, AMACR, α-methylacyl-CoA racemase, Medicine, biology, Cell growth, business.industry, CSS, charcoal-stripped serum, CRPC, castrate-resistant prostate cancer, ARV7, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, Androgen receptor, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, biology.protein, AR, androgen receptor, business, AMACR, medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cc2fec2c258ffc034e7d611f5a0db5
http://europepmc.org/articles/PMC8053692

المؤلفون: Sacha Ferdinandusse, Simone Denis, Phyllis L. Faust, Ronald J.A. Wanders

المصدر: Journal of Lipid Research, Vol 50, Iss 11, Pp 2139-2147 (2009)

مصطلحات موضوعية: dihydroxycholestanoic acid, trihydroxy-cholestanoic acid, peroxisome deficiency disorders, D-bifunctional protein deficiency, α-methylacyl-CoA racemase deficiency, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520306799; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/c9930892d08d493f995c0cd6ffbe84cf

المؤلفون: Sabine Rönicke, Nicol Kruska, Stefan Kahlert, Georg Reiser

المصدر: Neurobiology of Disease, Vol 36, Iss 2, Pp 401-410 (2009)

مصطلحات موضوعية: Refsum disease, Peroxisomal disorder, Mitochondrial potential, Reactive oxygen species, α-Methylacyl-CoA racemase deficiency, Phytanic acid (3,7,11,15-tetramethylhexadecanoic acid), Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996109002241; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/861a8049f2164bffa22d5e5f12111929

المؤلفون: Huan Xu, Xi Chen, Jin Ji, Chen Kong, Sun Yinghao, Zhi Cao, Yalong Xu, Fubo Wang

المصدر: Cancer Control : Journal of the Moffitt Cancer Center

مصطلحات موضوعية: Male, medicine.medical_specialty, Prostate biopsy, 030232 urology & nephrology, Urology, Racemases and Epimerases, Logistic regression, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Biopsy, medicine, Biomarkers, Tumor, Humans, prostate-specific antigen, Aged, medicine.diagnostic_test, business.industry, Area under the curve, Prostatic Neoplasms, biomarkers, Hematology, General Medicine, Rectal examination, medicine.disease, prostate cancer, α-methylacyl-CoA racemase, Confidence interval, Prostate-specific antigen, clinical diagnosis, Oncology, 030220 oncology & carcinogenesis, business, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cc1a766ce524862fe0a5107fa8c825
https://pubmed.ncbi.nlm.nih.gov/31793344

المؤلفون: Shapovalova, Mariya, Davydova, Julia, Henzler, Christine, Daniel, Mark, Dehm, Scott M., Warlick, Christopher A., LeBeau, Aaron M.

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Correction, adenovirus, molecular imaging, prostate cancer, α-methylacyl-CoA racemase, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b94ed3bb766ded3653076edd162cb19
https://pubmed.ncbi.nlm.nih.gov/31448058

المؤلفون: Tony D. James, Matthew D. Lloyd, Guat Ling Lee, Maksims Yevglevskis, Michael D. Threadgill, Yoana D. Petrova, Amit Nathubhai, Timothy J. Woodman

مصطلحات موضوعية: 0301 basic medicine, Cancer drugs, Racemases and Epimerases, Fatty acid degradation, Catalysis, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Hydroxybenzoates, Materials Chemistry, medicine, α methylacyl coa racemase, Humans, Structure–activity relationship, Enzyme Inhibitors, IC50, sub_chemistry, Dose-Response Relationship, Drug, Molecular Structure, top_sciences, Chemistry, Metals and Alloys, General Chemistry, Nitro Compounds, Ibuprofen, Molecular biology, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, 030104 developmental biology, Biochemistry, 030220 oncology & carcinogenesis, Ceramics and Composites, Colorimetry, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fde5572e00a8bccd7a2cd60fa69dc6
https://orca.cardiff.ac.uk/id/eprint/133378/1/c7cc00476a.pdf

المؤلفون: Seema Patrikar, Vikram Singh, V Manu, N.S. Mani, Ajay Malik, Vibha Dutta

المصدر: Journal of Cancer Research and Therapeutics, Vol 10, Iss 3, Pp 686-692 (2014)

مصطلحات موضوعية: Male, Pathology, medicine.medical_specialty, medicine.medical_treatment, Racemases and Epimerases, Sensitivity and Specificity, lcsh:RC254-282, Resection, Prostate, Biopsy, Biomarkers, Tumor, medicine, Humans, Radiology, Nuclear Medicine and imaging, High-grade prostatic intraepithelial neoplasia, α-methylacyl CoA racemase, medicine.diagnostic_test, Prostatectomy, business.industry, Tumor Suppressor Proteins, Biopsy, Needle, Transurethral Resection of Prostate, Prostatic Neoplasms, needle biopsy, General Medicine, suspicious foci, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.anatomical_structure, Oncology, Case-Control Studies, Needle biopsy, Monoclonal, immunohistochemistry, Immunohistochemistry, sense organs, business, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597e3066a9f4ef938586ec3737ba2235
http://www.cancerjournal.net/article.asp?issn=0973-1482;year=2014;volume=10;issue=3;spage=686;epage=692;aulast=Singh

المؤلفون: Zbigniew Lewandowski, Andrzej Mróz, Mirosław Kiedrowski

المصدر: Applied Immunohistochemistry & Molecular Morphology. 21:313-317

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Prognostic factor, Disease free survival, Histology, Racemases and Epimerases, Gastroenterology, Disease-Free Survival, Pathology and Forensic Medicine, Correlation, Predictive Value of Tests, Stomach Neoplasms, Internal medicine, medicine, α methylacyl coa racemase, Humans, Aged, Aged, 80 and over, business.industry, Reproducibility of Results, Cancer, Middle Aged, medicine.disease, Immunohistochemistry, Medical Laboratory Technology, Predictive value of tests, Adenocarcinoma, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812e7d5e54f56d29b31c448a60643989
https://doi.org/10.1097/pai.0b013e318268d034

المؤلفون: Lian Bai, Bin Jian, Gan He, Qiang Yang, Qugang Li, Zhongfu Li, Jiasheng Wang

المصدر: Oncology Letters

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Colorectal cancer, Population, 03 medical and health sciences, 0302 clinical medicine, colorectal carcinoma, Internal medicine, medicine, tumor protein p53, B-cell lymphoma 2, education, B-cell lymphoma, education.field_of_study, biology, business.industry, mindbomb E3 ubiquitin protein ligase 1, Cancer, Articles, medicine.disease, α-methylacyl-CoA racemase, Lymphoma, 030104 developmental biology, 030220 oncology & carcinogenesis, Ki-67, biology.protein, Biomarker (medicine), Immunohistochemistry, biomarker, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e3c17edc83a4f42230dea9fe749076
https://pubmed.ncbi.nlm.nih.gov/29844818

المؤلفون: Selkälä, E. (Eija)

المساهمون: Hiltunen, K. (Kalervo), Autio, K. (Kaija)

مصطلحات موضوعية: bile acids, phytol, fytoli, peroxisomal disorders, sappihapot, peroksisomitaudit, metabolic regulation, α-methylacyl-CoA racemase, aineenvaihdunnan säätely, α-metyyliasyyli-koentsyymi-A-rasemaasi

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______2423::d70879001f0808fa1300c0ce9b494ec2
http://urn.fi/urn:isbn:9789526211718

المؤلفون: Grażyna Odrowąż-Sypniewska, Joanna Siódmiak, Michał Piotr Marszałł, Piotr Słupski, Marek Adamowski, Piotr Jarzemski, Wiktor Dariusz Sroka

مصطلحات موضوعية: Male, Cancer Research, medicine.medical_specialty, Pathology, Prostate biopsy, Hepsin, Urinary system, Clinical Biochemistry, Urology, Prostatic Hyperplasia, Racemases and Epimerases, Alpha-methylacyl-CoA racemase, urologic and male genital diseases, Pathology and Forensic Medicine, Prostate cancer, medicine, Biomarkers, Tumor, Humans, Aged, Prostate massage, Aged, 80 and over, medicine.diagnostic_test, business.industry, Serine Endopeptidases, Prostatic Neoplasms, Rectal examination, Middle Aged, Prostate-Specific Antigen, medicine.disease, prostate cancer, Oncology, ROC Curve, Case-Control Studies, Biomarker (medicine), biomarker, Kallikreins, business, human serine protease, hepsin, α-Methylacyl-CoA racemase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d4aa97e7227e3b110e14e9dfed60f10
http://repozytorium.umk.pl/handle/item/3065

المؤلفون: Maha M. Shamloula, Hassan T. Sheir

المصدر: Egyptian Journal of Pathology. 32:42-46

مصطلحات موضوعية: biology, business.industry, biology.protein, α methylacyl coa racemase, Medicine, Cyclooxygenase, business, Molecular biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f6bfd5b3cc71f0bea0060e5222ba62f5
https://doi.org/10.1097/01.xej.0000415727.95935.97

المؤلفون: Sun Mi Kim, Hee-Jae Cha, Min Kyung Cho, Mee-Sun Ock, Bong Jin Kim, Yongseok Lee, Hak Sun Yu

المصدر: The Korean Journal of Parasitology

مصطلحات موضوعية: Molecular Sequence Data, Racemases and Epimerases, immunoscreening, cDNA library, Brief Communication, excretory-secretory product, Alpha-methylacyl-CoA racemase, Anisakis, Mice, Complementary DNA, Gene expression, Animals, Cluster Analysis, Humans, Amino Acid Sequence, Cloning, Molecular, α-methylacyl CoA racemase, Phylogeny, Gene Library, Mice, Inbred ICR, Sequence Homology, Amino Acid, biology, Gene Expression Profiling, Anisakis simplex, biology.organism_classification, Immunohistochemistry, Molecular biology, Open reading frame, Infectious Diseases, Biochemistry, Polyclonal antibodies, Larva, biology.protein, Parasitology, Rabbits, Anisakis simplex L3

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3ac17da69b027ddeec6432db79ad47
https://doi.org/10.3347/kjp.2012.50.2.165