المؤلفون: Yifan Wang, Zhengmei He, Xinyu Dong, Yiming Yao, Qiuni Chen, Yuye Shi, Yuan Deng, Quane Zhang, Liang Yu, Chunling Wang

المصدر: Frontiers in Pharmacology, Vol 15 (2025)

مصطلحات موضوعية: ferroptosis, STAT3, Nfr2, ZEB1, IKE, α-KG, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1458412/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/9186b05ce9ff4cba982315d5eeef43e4

المؤلفون: Ran Ding, Yongfeng Zhou, Qi Zhang, Xiangjie Kong, Qi Li, Sheng Zhang, Yibing Chen, Xinglan An, Ziyi Li

المصدر: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

مصطلحات موضوعية: Myc, α-KG, metabolism, demethylation, early embryos, pigs, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1507102/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/34277e0cd50a4e38b8fd3564ffb1989a

المؤلفون: Andrey Volnitskiy, Konstantin Shabalin, Rimma Pantina, Elena Varfolomeeva, Roman Kovalev, Vladimir Burdakov, Svetlana Emelianova, Luiza Garaeva, Alexander Yakimov, Marina Sogoyan, Michael Filatov, Andrey L. Konevega, Tatiana Shtam

المصدر: Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1107-1120 (2024)

مصطلحات موضوعية: glioma, OCT4, α-KG, metabolic cell reprogramming, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/2/70; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

URL الوصول: https://doaj.org/article/240e4b208c2f418dbc1bf9dccd2c40d6

المؤلفون: Ji‐Yan Wang, Xin‐Tong Dai, Qing‐Le Gao, Hong‐Kai Chang, Shuai Zhang, Chang‐Liang Shan, Tao He

المصدر: Ibrain, Vol 9, Iss 2, Pp 133-147 (2023)

مصطلحات موضوعية: fumarate, glioma, immune evasion, tyrosine metabolism, α‐KG, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2769-2795

URL الوصول: https://doaj.org/article/186cbac1f76941379f3b443df02d6212

المؤلفون: Shuhui Niu, Fang Liu, Yaping Wang, Ben Rao, Yueying Wang

المصدر: Molecules, Vol 29, Iss 8, p 1861 (2024)

مصطلحات موضوعية: alpha-ketoglutaric acid (α-KG), L-glutamate oxidase, catalase, whole-cell catalysis, Organic chemistry, QD241-441

Relation: https://www.mdpi.com/1420-3049/29/8/1861; https://doaj.org/toc/1420-3049; https://doaj.org/article/3661a23ceeb444a3a899033e35133941

الاتاحة: https://doi.org/10.3390/molecules29081861
https://doaj.org/article/3661a23ceeb444a3a899033e35133941

المؤلفون: Mengke Fan, Huiying Shi, Hailing Yao, Weijun Wang, Yurui Zhang, Chen Jiang, Rong Lin

المصدر: Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-17 (2022)

مصطلحات موضوعية: Bone marrow-derived mesenchymal stem cells (BMSCs), α-ketoglutarate (α-KG), Glud1 (glutamate dehydrogenase 1), Histone methylation, Medicine (General), R5-920, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-6512

URL الوصول: https://doaj.org/article/025c02c073124aa88c635025c2b9cb68

المؤلفون: Zheyi Xiang, Le Bai, Jennifer Q. Zhou, Ricardo R. Cevallos, Jonathan R. Sanders, Gang Liu, Karen Bernard, Yan Y. Sanders

المصدر: Molecular Metabolism, Vol 67, Iss , Pp 101655- (2023)

مصطلحات موضوعية: Glutamine, α-KG, H3K27me3, Col3A1, PLK1, Lung fibrosis, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877822002241; https://doaj.org/toc/2212-8778

URL الوصول: https://doaj.org/article/dd95ae331d94429bab83a46d0b50dd73

المؤلفون: Quinteros, Susel Loli, von Krusenstiern, Eliana, Snyder, Nathaniel, Tanaka, Akane, O'Brien, Bronwyn, Donnelly, Sheila, Snyder|0000-0001-5643-8747

مصطلحات موضوعية: Fasciola hepatica, Alpha-ketoglutarate (α-KG), Fatty acid oxidation (FAO), Glutaminolysis, Helminth defence molecule, Immune regulation, Immunometabolism, Macrophage

وصف الملف: 12 pages

Relation: Frontiers Media; https://doi.org/10.3389/fimmu.2023.1018076; Frontiers in Immunology, Vol. 14; Faculty/ Researcher Works; http://hdl.handle.net/20.500.12613/10870

الاتاحة: https://hdl.handle.net/20.500.12613/10870

المؤلفون: Jianhong An, Jiaojiao Guan, Yao Nie

المصدر: Molecules; Volume 28; Issue 9; Pages: 3750

مصطلحات موضوعية: Fe (II)/α-KG-dependent dioxygenases, L-isoleucine dioxygenase, aromatic amino acid

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Organic Chemistry; https://dx.doi.org/10.3390/molecules28093750

الاتاحة: https://doi.org/10.3390/molecules28093750

المؤلفون: Tan Zhang, Liqun Yuan, Minfeng Sheng, Yanming Chen, Ji Wang, Qing Lan

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: IDH mutation, α-KG, 2-HG, lower-grade glioma, genome-wide analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.840394/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/0dcffdcdcdab4b13a2325014862a8da5

المؤلفون: Katsuya Nagaoka, Joud Mulla, Kevin Cao, Zhixiang Cheng, Dan Liu, William Mueller, Amalia Bay, Grace Hildebrand, Shaolei Lu, Chiung-Kuei Huang

المصدر: Liver Research, Vol 4, Iss 2, Pp 94-100 (2020)

مصطلحات موضوعية: Peroxisome proliferator-activated receptor gamma (PPARγ), Steatosis, Non-alcoholic fatty liver disease (NAFLD), Non-alcoholic steatohepatitis (NASH), Alpha-ketoglutarate (α-KG), Gender difference, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2542568420300209; https://doaj.org/toc/2542-5684

URL الوصول: https://doaj.org/article/111cbfa542964916b00966c813adc782

المؤلفون: Qiwei He, Junxiong Chen, Zijing Xie, Zhenzhou Chen

المصدر: Cancers; Volume 14; Issue 23; Pages: 5779

مصطلحات موضوعية: isocitrate dehydrogenase (IDH), cancer metabolism, oxidative decarboxylation, reductive carboxylation, α-ketoglutarate (α-KG), nicotinamide adenine dinucleotide phosphate (NADPH)

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers14235779

الاتاحة: https://doi.org/10.3390/cancers14235779

المؤلفون: Yong Ryoul Yang, Ki-Sun Kwon

المصدر: Frontiers in Physiology, Vol 11 (2020)

مصطلحات موضوعية: exercise, metabolites, alpha-ketoglutarate (α-KG), beta-aminoisobutyric acid (BAIBA), kynurenic acid (KYNA), β-hydroxybutyrate (BHB), Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2020.602748/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/e57186330cbc4ad88a71e91883e05884

المؤلفون: Zhang, Z, He, C, Gao, Y, Zhang, L, Song, Y, Zhu, T, Zhu, K, Lv, D, Wang, J, Tian, X, Ma, T, Ji, P, Cui, W, Liu, G

المصدر: 15 ; 1

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Cell Biology, Geriatrics & Gerontology, mTOR, ovarian aging, reproduction, telomere, alpha-KG, α-KG, 06 Biological Sciences, 11 Medical and Health Sciences, Developmental Biology

Relation: Aging Cell; http://hdl.handle.net/10044/1/85989

الاتاحة: http://hdl.handle.net/10044/1/85989
https://doi.org/10.1111/acel.13291

المؤلفون: Bergaggio E., Piva R.

المساهمون: Bergaggio E., Piva R.

مصطلحات موضوعية: Combination therapy, DNA damage, Isocitrate dehydrogenase (IDH), Non-oncogenic addition, Reactive oxygen species (ROS), Reference, Wild-type IDH inhibitor, α -ketoglutarate (α KG)

Relation: info:eu-repo/semantics/altIdentifier/pmid/31010244; info:eu-repo/semantics/altIdentifier/wos/WOS:000467773400131; volume:11; issue:4; firstpage:563; lastpage:573; numberofpages:11; journal:CANCERS; http://hdl.handle.net/2318/1760654; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85065400310; https://www.mdpi.com/2072-6694/11/4/563/pdf

الاتاحة: http://hdl.handle.net/2318/1760654
https://doi.org/10.3390/cancers11040563
https://www.mdpi.com/2072-6694/11/4/563/pdf

المؤلفون: Susel Loli Quinteros, Eliana von Krusenstiern, Nathaniel W. Snyder, Akane Tanaka, Bronwyn O’Brien, Sheila Donnelly

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, Fasciola hepatica, helminth defence molecule, macrophage, immunometabolism, glutaminolysis, immune regulation, alpha-ketoglutarate (α-KG), fatty acid oxidation (FAO)

Relation: https://figshare.com/articles/dataset/DataSheet_1_The_helminth_derived_peptide_FhHDM-1_redirects_macrophage_metabolism_towards_glutaminolysis_to_regulate_the_pro-inflammatory_response_docx/21952118

الاتاحة: https://doi.org/10.3389/fimmu.2023.1018076.s001
https://figshare.com/articles/dataset/DataSheet_1_The_helminth_derived_peptide_FhHDM-1_redirects_macrophage_metabolism_towards_glutaminolysis_to_regulate_the_pro-inflammatory_response_docx/21952118

المؤلفون: Hanumantha Madala, Surendra Punganuru, Viswanath Arutla, Subhasis Misra, T. Thomas, Kalkunte Srivenugopal

المصدر: Cancers; Volume 10; Issue 2; Pages: 49

مصطلحات موضوعية: IDH mutations, D-2 hydroxyglutarate, epigenetic effects, hydroxy-methyl cytosine, histone methylations, glioblastoma, hematopoietic cancers, α-KG-dependent dioxygenases

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers10020049

الاتاحة: https://doi.org/10.3390/cancers10020049

المؤلفون: Bonnie Ky, Anja Karlstaedt, Matthew Barrett, Seth Thomas Gammons, Ray Hu

المصدر: JACC: Basic to Translational Science

مصطلحات موضوعية: medicine.medical_specialty, cardio-oncology, [18F]FDG, 2-deoxy-2-[fluorine-18]fluoro-D-glucose, PTM, post-translational modification, IGF, insulin-like growth factor, SGLT2, sodium glucose co-transporter 2, oncometabolism, 99mTc-MIBI, 99mtechnetium-sestamibi, FASN, fatty acid synthase, Cardiac metabolism, heart failure, IDH, isocitrate dehydrogenase, Cardiovascular care, Context (language use), Disease, CVD, cardiovascular disease, D2-HG, D-2-hydroxyglutarate, HF, heart failure, PET, positron emission tomography, GLS, glutaminase, TRF, time-restricted feeding, medicine, cancer, PI3K, insulin-activated phosphoinositide-3-kinase, Cancer biology, Cardio oncology, Intensive care medicine, α-KG, α-ketoglutarate, MCT1, monocarboxylate transporter 1, Cancer, MRS, magnetic resonance spectroscopy, medicine.disease, PDH, pyruvate dehydrogenase, State-of-the-Art Review, Cardiology and Cardiovascular Medicine, metabolism, FAO, fatty acid oxidation, Potential toxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68748cb7277a02618d388f95ef5a04f2
http://europepmc.org/articles/PMC8385559

المؤلفون: Shengtao Yuan, Han Luwei, Dezhen Peng, Zhiqiang Wang, Hongzhi Du, Li Sun, Zhang Xian, Zhao Liwen, Danyu Du, Ligong Lu, Meixiao Zhan, Zhibo Zhang, Yong Li

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1526-1540 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: BCRP, breast cancer resistance protein, Metabolite, OATP, organic anion transporting polypeptide, IC50, half maximal inhibitory concentration, Preclinical efficacy, Papp, apparent permeability coefficient, chemistry.chemical_compound, 0302 clinical medicine, LC–MS/MS, liquid chromatography–tandem mass spectrometry, Medicine, PDX, patient-derived tumor xenograft, General Pharmacology, Toxicology and Pharmaceutics, AML, acute myeloid leukemia, MDR1, multidrug resistance protein 1, media_common, 0303 health sciences, α-KG, α-ketoglutaric acid, mIDH2 inhibitor, 2-Hydroxyglutarate, ADME, absorption, distribution, metabolism and excretion, 030220 oncology & carcinogenesis, Differentiation, CYP, cytochrome P450, Original Article, Drug, 2-HG, 2-hydroxyglutaric acid, Mutant isocitrate dehydrogenase 2 (mIDH2), media_common.quotation_subject, CDX, cell-line-derived xenograft, RM1-950, IDH2, Acute myeloid leukaemia, 03 medical and health sciences, mIDH2, mutant isocitrate dehydrogenase, Pharmacokinetics, SH1573, AUC, area under the cure, AG-221, enasidenib, Tumor metabolism, Carcinogen, 030304 developmental biology, PD, pharamacodynamics, business.industry, OCT, organ cation transporter, Clinical trial, chemistry, Cell culture, Pharmacodynamics, Cancer research, OAT, organic anion transporter, PK, pharmacokinetics, Therapeutics. Pharmacology, business, EPO, erythropoietin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1989ebe7a9db18d2c8b52de1673685c1
http://www.sciencedirect.com/science/article/pii/S2211383521000769

المؤلفون: Theodosiou, Eleni, Breisch, M., Julsing, M.K., Falcioni, F., Bühler, Bruno, Schmid, Andreas

المصدر: ISSN: 0006-3592.

مصطلحات موضوعية: whole-cell biocatalysis, TCA cycle engineering, α-KG dependent dioxygenase, l-proline transporter, proline hydroxylation

وصف الملف: application/pdf

Relation: https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=18559; https://dx.doi.org/10.1002/bit.26281

الاتاحة: https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=18559
https://doi.org/10.1002/bit.26281