المؤلفون: Sirinapa Thangsiri, Woorawee Inthachat, Piya Temviriyanukul, Yuraporn Sahasakul, Piyapat Trisonthi, Wanida Pan-utai, Dalad Siriwan, Uthaiwan Suttisansanee

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: Algae, Alzheimer’s disease, Β-secretase, Diabetes, Enzyme inhibition, Phenolics, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/77bde799c9954094a60f4401ee563ebf

المؤلفون: Richa Arya, Smita Jain, Sarvesh Paliwal, Kirtika Madan, Swapnil Sharma, Achal Mishra, Prashant Tiwari, Sunil Kumar Kadiri

المصدر: Asian Pacific Journal of Tropical Biomedicine, Vol 14, Iss 9, Pp 369-381 (2024)

مصطلحات موضوعية: bace1 inhibitors, amyloid precursor protein, β-secretase, structure-based drug design, 3d-qsar, β-amyloid precursor protein, Arctic medicine. Tropical medicine, RC955-962, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://journals.lww.com/10.4103/apjtb.apjtb_192_24; https://doaj.org/toc/2221-1691; https://doaj.org/toc/2588-9222

URL الوصول: https://doaj.org/article/951eb488d02145528b4cd5f5f3dabbf5

المؤلفون: Ya Su, Qiong Wang, Feng Gao, Jiajie Xu, Jiayu Fu, Yunqing Ying, Yiwei Xia, Xiaoxiao Wang, Qiang Dong, Yong Shen, Xin Cheng

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 24 (2024)

مصطلحات موضوعية: cerebral amyloid angiopathy, cerebral small vessel disease, hypertensive arteriopathy, neurodegeneration, β‐secretase 1, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2047-9980

URL الوصول: https://doaj.org/article/f927a15129874784bfc8ae37ab73f56a

المؤلفون: Takeru Nagayama, Sosuke Yagishita, Megumi Shibata, Akiko Furuno, Takashi Saito, Takaomi C. Saido, Shuji Wakatsuki, Toshiyuki Araki

المصدر: Neuroscience Research, Vol 205, Iss , Pp 40-46 (2024)

مصطلحات موضوعية: Sleep-disordered breathing, Sleep apnea, Chronic intermittent hypoxia, Alzheimer, Disease (AD), β-Secretase 1 (BACE1), Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0168010224000415; https://doaj.org/toc/0168-0102

URL الوصول: https://doaj.org/article/2970af987d6f457b9f2fbe1bf4d1e0a0

المؤلفون: Md. Enamul Kabir Talukder, Shahina Akhter, Foysal Ahammad, Asmim Aktar, Md. Saidul Islam, Aysha Akter Laboni, Mirola Afroze, Mala Khan, Mohammad Jashim Uddin, Md. Mashiar Rahman

المصدر: Heliyon, Vol 10, Iss 17, Pp e37178- (2024)

مصطلحات موضوعية: Argemone mexicana L., Alzheimer’s disease, Phytochemicals, Acetylcholinesterase, Butyrylcholinesterase, β-secretase, Science (General), Q1-390, Social sciences (General), H1-99

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024132094; https://doaj.org/toc/2405-8440

URL الوصول: https://doaj.org/article/a13dc491c10e44cb9a19b79cc98a72e6

المؤلفون: Michael C. Ojo, Rebamang A. Mosa, Foluso O. Osunsanmi, Neerish Revaprasadu, Andy R. Opoku

المصدر: Electronic Journal of Biotechnology, Vol 68, Iss , Pp 67-80 (2024)

مصطلحات موضوعية: Acetylcholinesterase, Alzheimer’s disease, Anti-aggregation, β-amyloid (Aβ), Bauhinia bowkeri, β-secretase, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0717345823000386; https://doaj.org/toc/0717-3458

URL الوصول: https://doaj.org/article/861a9b6d874443bcb133ebc9294281fe

المؤلفون: Malathi, R¹, Dsouza, Vailina², Puja³, Rithika, R⁴, Sneha, P⁵

المصدر: Research Journal of Pharmacy and Technology 16(12):5813-5817. 2023

المؤلفون: S. Vorobev, S. Yanishevskiy, S. Efimtsev, A. Sokolov, V. Dyachuk

المصدر: Frontiers in Aging Neuroscience, Vol 16 (2024)

مصطلحات موضوعية: neurodegeneration, capillary dysfunction, mitochondrial dysfunction, oxidative stress, β-secretase pathway, BBB function, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2024.1458455/full; https://doaj.org/toc/1663-4365

URL الوصول: https://doaj.org/article/c2eda1848ea84405b6599dc5091c2d66

المؤلفون: Xu Han, Kaibo Guo

المصدر: Frontiers in Chemistry, Vol 12 (2024)

مصطلحات موضوعية: pharmacophore-based virtual screening, β-secretase 1, Alzheimer’s disease, databases, crystal structure, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fchem.2024.1412349/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/034131e897bc45a79b70c7a89e1a735f

المؤلفون: Eduardo Suárez-González, Jesús Sandoval-Ramírez, Jorge Flores-Hernández, Alan Carrasco-Carballo

المصدر: Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9674-9691 (2023)

مصطلحات موضوعية: ROS, CNS, AChE, MAO-A, MAO-B, β-secretase, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1467-3045/45/12/604; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

URL الوصول: https://doaj.org/article/e209a2a5dba942739044e3c4fa3e8151

المؤلفون: Takahiro Katsuki, Kayako Ogi, Ayaka Kinno, Shingo Kasamatsu, Hideshi Ihara, Hidenobu Sumitani

المصدر: Foods, Vol 13, Iss 18, p 2858 (2024)

مصطلحات موضوعية: Alzheimer’s disease, β-secretase, whitebait, functional food-derived ingredient, Chemical technology, TP1-1185

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2304-8158/13/18/2858; https://doaj.org/toc/2304-8158

URL الوصول: https://doaj.org/article/4aaec78a7b9e4e47a8fb62a66739d7cb

المؤلفون: Coma Camprodón, Mireia

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Valverde, M. A. (Miguel Ángel), Muñoz López, Francisco José

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Antioxidants, Endothelial cells, Nitrotyrosination, Vascular smooth muscle cells, Nitric oxide, Oxidative stress, Estrogen, Cerebral amyloid angiopathy, β-secretase, Alzheimer's disease, Arnyloid-β-peptide, Múscul llis vascular, Cèl·lules endotelials, Nitrotirosinació, Òxid nítric, Estrès oxidatiu, pèptid B-amiloide, β-secretasa, Malaltia d'Alzheimer, Angiopatia cerebral amiloidea

Time: 616.8

وصف الملف: application/pdf

URL الوصول: http://www.tdx.cat/TDX-0521110-113337
http://hdl.handle.net/10803/7110

المؤلفون: Tai Kyoung Kim, Yongeun Cho, Jaewon Kim, Jeongmi Lee, Ju-Mi Hong, Heewon Cho, Jun-Sik Kim, Yeongyeong Lee, Kyung Hee Kim, Il-Chan Kim, Se Jong Han, Hyuncheol Oh, Dong-Gyu Jo, Joung Han Yim

المصدر: Molecules, Vol 29, Iss 15, p 3701 (2024)

مصطلحات موضوعية: Alzheimer’s disease, Ramalin, derivatives, antioxidant, anti-inflammatory, β-secretase, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/15/3701; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/8503256eb9b944b28f049e31901f13e6

المؤلفون: Tai Kyoung Kim, Ju-Mi Hong, Jaewon Kim, Kyung Hee Kim, Se Jong Han, Il-Chan Kim, Hyuncheol Oh, Dong-Gyu Jo, Joung Han Yim

المصدر: Molecules ; Volume 29 ; Issue 22 ; Pages: 5223

مصطلحات موضوعية: Alzheimer’s disease, Ramalin, derivatives, therapeutic potential, antioxidant, tau protein, β-secretase, anti-inflammatory, Ames

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Organic Chemistry; https://dx.doi.org/10.3390/molecules29225223

الاتاحة: https://doi.org/10.3390/molecules29225223

المؤلفون: Shuli LIAN, Jing XU, Manqiong YUAN

المصدر: Zhongguo gonggong weisheng, Vol 39, Iss 5, Pp 660-664 (2023)

مصطلحات موضوعية: alzheimer′s disease, biomarker, amyloid-β protein, tau protein, β-secretase 1, neurofilament light chain, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1001-0580

URL الوصول: https://doaj.org/article/e704a598a02740508827741f29acffa1

المؤلفون: Rajão‐saraiva, Joana, Dunot, Jade, Ribera, Aurore, Temido-Ferreira, Mariana, Coelho, Joana, E, König, Svenja, Moreno, Sébastien, Enguita, Francisco, J, Willem, Michael, Kins, Stefan, Marie, Hélène, Lopes, Luísa, V, Pousinha, Paula, A

المساهمون: Université Côte d'Azur (UniCA), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA)

المصدر: ISSN: 1474-9718.

مصطلحات موضوعية: Aβ, amyloid beta BACE1, β-secretase 1 BI, β-secretase 1 inhibitor Ca2+, Calcium CTFs, APP C-terminal fragments CTFα, APP C-terminal fragment α CTFβ, APP C-terminal fragment β cTKO, triple conditional knockout DIV, days in vitro EPSCs, excitatory postsynaptic currents fEPSPs, field excitatory postsynaptic potentials Ifen, ifenprodil IPTG, Isopropyl β-D-1-thiogalactopyranoside LTD, long-term depression LTP, long-term potentiation MAPT, microtubule-associated protein tau NMDAR, N-methyl-D-aspartate receptors NS1, nonsilencing sequence pGluN2B, phosphorylated GluN2B PSD, postsynaptic density PSD-95, Postsynaptic density protein 95 PSEN1, presenilin-1 PTB1-p, PTB1 peptide PTB2-p, PTB2 peptide PVDF, polyvinylidene fluoride ROI, region of interest RT, room temperature sAPPα, secreted APP α sAPPβ, secreted APP β SEM

Relation: hal-04275549; https://hal.science/hal-04275549; https://hal.science/hal-04275549/document; https://hal.science/hal-04275549/file/Rajao_Saraiva_Aging%20Cell_2023.pdf

الاتاحة: https://hal.science/hal-04275549
https://hal.science/hal-04275549/document
https://hal.science/hal-04275549/file/Rajao_Saraiva_Aging%20Cell_2023.pdf
https://doi.org/10.1111/acel.13778

المؤلفون: Yaqi Wang, Yuting Cui, Jing Liu, Qiao Song, Min Cao, Yuli Hou, Xiaomin Zhang, Peichang Wang

المصدر: Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Alzheimer’s disease, KLF5, β-Secretase, Amyloid precursor protein, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1758-9193

URL الوصول: https://doaj.org/article/806fca1879e74f7cb5cc43905fd2dbad

المؤلفون: Qi, Xiaoping, Francelin, Carolina, Mitter, Sayak, Boye, Sanford L., Gu, Hongmei, Quigley, Judith, Grant, Maria B., Boulton, Michael E.

المساهمون: Ophthalmology, School of Medicine

المصدر: PMC

مصطلحات موضوعية: β-secretase 1, Retinal degeneration, Age-related macular degeneration, Gene therapy, Retinal pigment epithelium

وصف الملف: application/pdf

Relation: Molecular Therapy; Qi X, Francelin C, Mitter S, et al. β-secretase 1 overexpression by AAV-mediated gene delivery prevents retina degeneration in a mouse model of age-related macular degeneration. Mol Ther. 2023;31(7):2042-2055. doi:10.1016/j.ymthe.2023.03.029; https://hdl.handle.net/1805/43353

الاتاحة: https://hdl.handle.net/1805/43353

المؤلفون: Shiveena Bhatia, Manjinder Singh, Pratibha Sharma, Somdutt Mujwar, Varinder Singh, Krishna Kumar Mishra, Thakur Gurjeet Singh, Tanveer Singh, Sheikh Fayaz Ahmad

المصدر: Molecules; Volume 28; Issue 16; Pages: 6032

مصطلحات موضوعية: Alzheimer’s disease, β-secretase, β-amyloid, BACE-1, dementia, elenbecestat

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Computational and Theoretical Chemistry; https://dx.doi.org/10.3390/molecules28166032

الاتاحة: https://doi.org/10.3390/molecules28166032

المؤلفون: Géssica Oliveira Mendes, Samuel Silva da Rocha Pita, Paulo Batista de Carvalho, Michel Pires da Silva, Alex Gutterres Taranto, Franco Henrique Andrade Leite

المصدر: Pharmaceuticals; Volume 16; Issue 6; Pages: 880

مصطلحات موضوعية: molecular hybrids, Alzheimer’s disease, cholinesterase, human β -secretase 1, molecular dynamics

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/ph16060880

الاتاحة: https://doi.org/10.3390/ph16060880