المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

المصدر: PLoS Pathogens, Vol 20, Iss 1, p e1011557 (2024)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011557&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/237ca26c1906426da1acea6b60a8f15a

المؤلفون: Àngel Fenollar, Albert Ros-Lucas, María Pía Alberione, Nieves Martínez-Peinado, Miriam Ramírez, Miguel Ángel Rosales-Motos, Ling Y. Lee, Julio Alonso-Padilla, Luis Izquierdo

المصدر: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 850-863 (2022)

مصطلحات موضوعية: Malaria, Plasmodium falciparum, GPI-anchors, N-glycosylation, Inhibitors, Antiplasmodial activity, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037022000368; https://doaj.org/toc/2001-0370

URL الوصول: https://doaj.org/article/ed8b307435744cd396ba8358f429af7a

المؤلفون: Nieves Martinez-Peinado, Álvaro Lorente-Macías, Alejandro García-Salguero, Nuria Cortes-Serra, Ángel Fenollar-Collado, Albert Ros-Lucas, Joaquim Gascon, Maria-Jesus Pinazo, Ignacio J. Molina, Asier Unciti-Broceta, Juan J. Díaz-Mochón, María J. Pineda de las Infantas y Villatoro, Luis Izquierdo, Julio Alonso-Padilla

المصدر: Pharmaceuticals; Volume 14; Issue 7; Pages: 638

مصطلحات موضوعية: Plasmodium falciparum, Trypanosoma cruzi, purine metabolism, purine derivatives, pyrimidine analogs, phenotypic assays, cytotoxicity assays

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/ph14070638

الاتاحة: https://doi.org/10.3390/ph14070638

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/S1_Fig_-/25077903

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.s001
https://figshare.com/articles/figure/S1_Fig_-/25077903

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Phylogenetic_analysis_of_the_retrieved_representative_prenol_binding_proteins_/25078021

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.s003
https://figshare.com/articles/figure/Phylogenetic_analysis_of_the_retrieved_representative_prenol_binding_proteins_/25078021

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Recodonized_i_Pf_i_PolK_sequence_/25078030

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.s006
https://figshare.com/articles/figure/Recodonized_i_Pf_i_PolK_sequence_/25078030

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Phylogenetic_analysis_of_dolichol_kinase_/25078024

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.s004
https://figshare.com/articles/figure/Phylogenetic_analysis_of_dolichol_kinase_/25078024

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Additional_Western_blot_and_immunofluorescence_experiments_/25078027

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.s005
https://figshare.com/articles/figure/Additional_Western_blot_and_immunofluorescence_experiments_/25078027

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Sequence_alignment_/25078018

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.s002
https://figshare.com/articles/figure/Sequence_alignment_/25078018

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Chromatographic_analisis_of_standards_/25078033

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.s007
https://figshare.com/articles/figure/Chromatographic_analisis_of_standards_/25078033

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Isoprenoid_sources_and_distribution_in_malaria_parasites_/25078036

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.g001
https://figshare.com/articles/figure/Isoprenoid_sources_and_distribution_in_malaria_parasites_/25078036

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/_i_Pf_i_PolK_phylogenetic_analysis_and_structural_model_/25078039

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.g002
https://figshare.com/articles/figure/_i_Pf_i_PolK_phylogenetic_analysis_and_structural_model_/25078039

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Farnesol_and_isoleucine_incorporation_into_proteins_in_-PolK_parasites_/25078054

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.g006
https://figshare.com/articles/figure/Farnesol_and_isoleucine_incorporation_into_proteins_in_-PolK_parasites_/25078054

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Sensitivity_to_fosmidomycin_using_human_plasma_/25078057

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.g007
https://figshare.com/articles/figure/Sensitivity_to_fosmidomycin_using_human_plasma_/25078057

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Farnesol_and_geranylgeraniol_kinase_activities_/25078042

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.g003
https://figshare.com/articles/figure/Farnesol_and_geranylgeraniol_kinase_activities_/25078042

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Conditional_knockout_of_i_P_i_i_falciparum_i_PolK_gene_/25078045

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.g004
https://figshare.com/articles/figure/Conditional_knockout_of_i_P_i_i_falciparum_i_PolK_gene_/25078045

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/figure/Phenotypic_characterization_of_knockout_parasites_/25078048

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.g005
https://figshare.com/articles/figure/Phenotypic_characterization_of_knockout_parasites_/25078048

المؤلفون: Marcell Crispim, Ignasi Bofill Verdaguer, Agustín Hernández, Thales Kronenberger, Àngel Fenollar, Lydia Fumiko Yamaguchi, María Pía Alberione, Miriam Ramirez, Sandra Souza de Oliveira, Alejandro Miguel Katzin, Luis Izquierdo

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, several essential metabolites, displayed increased susceptibility, bovine supplements used, transmembrane prenol kinase, transgenic parasites revealed, saccharomyces cerevisiae <, novel kinase required, de novo <, conditional knockout parasites, ggoh kinase activities, study also identifies, div >< p, delipidated human plasma, polk parasites lost, mep inhibitors could, ggoh salvage pathway, human plasma, rescue parasites, prenol utilization, polk parasites, p <, novel kind

Relation: https://figshare.com/articles/dataset/MRM_transition_of_FOH_and_GGOH_/25078060

الاتاحة: https://doi.org/10.1371/journal.ppat.1011557.t001
https://figshare.com/articles/dataset/MRM_transition_of_FOH_and_GGOH_/25078060