المؤلفون: Yassine Rhazi, Riham Sghyar, Noemi Deak, Bouchra Es-Sounni, Bouchra Rossafi, Albert Soran, Mustapha Laghmari, Azize Arzine, Asmae Nakkabi, Khalil Hammani, Samir Chtita, Mohammed M. Alanazi, Gabriela Nemes, Mohamed El. Yazidi

المصدر: Pharmaceuticals, Vol 17, Iss 10, p 1390 (2024)

مصطلحات موضوعية: quinazolin-(3H)-one, isoxazole, DFT mechanistic study, antioxidant agents, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/10/1390; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/be6418b079f6480bbb45c4459d2172ae

المؤلفون: Xueer Zhang, Caijin Lei, Jie Tang, Guangbin Cheng, Hongwei Yang

مصطلحات موضوعية: Pharmacology, Virology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, differential scanning calorimetry, 318 ° c, ide (< b, 360 n ), v , 13 , 4 ′, 2 ′, 3 , 1 , , ir ), 240 n, p <, >< sub, thermogravimetric analysis, tga ), ray diffraction, insensitive explosive, elemental analysis, crystal structures, bright future, >- quinazolin, >, 5 j

Time: 6, 4, 3

Relation: https://figshare.com/articles/journal_contribution/Synthesis_of_High-Thermostability_and_Low-Sensitivity_6_6_-Fused_Energetic_Compound_Based_on_Benzene_and_Pyrimidine/24977469

الاتاحة: https://doi.org/10.1021/acs.cgd.3c01314.s001
https://figshare.com/articles/journal_contribution/Synthesis_of_High-Thermostability_and_Low-Sensitivity_6_6_-Fused_Energetic_Compound_Based_on_Benzene_and_Pyrimidine/24977469

المؤلفون: Kavitha, K^{1, 1}, Srinivasan, N², Mohan, S¹, Suresh, R²

المصدر: Research Journal of Pharmacy and Technology 14(9):4849-4855. 2021

المؤلفون: Nan Wu, Yehui Yang, Guangmin Tian, Lian An, Songsong Liu, Taisen Yan, Mingyan Yi, Xiaoping Bao

مصطلحات موضوعية: Biochemistry, Pharmacology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo protection efficacy, tested phytopathogenic bacteria, ray diffraction analysis, potted rice plants, experimental results revealed, commercialized bactericide bismerthiazol, efficient anti -<, maximal effective concentration, f5 , f33 , f19 , 50 , b <, xoo <, h <, 50 μg, 4 -<, thiadiazole scaffold, thiadiazole moiety, phytophthora nicotianae, oryzae (<, new quinazolin, inhibition rate, different biophysical

Relation: https://figshare.com/articles/journal_contribution/Synthesis_X_ray_Crystal_Structure_and_Antimicrobial_Studies_of_New_Quinazolin-4_3_i_H_i_one_Derivatives_Containing_the_1_2_4-Triazolo_3_4_i_b_i_1_3_4_thiadiazole_Moiety_and_4_Piperidinyl_Linker/24712410

الاتاحة: https://doi.org/10.1021/acs.jafc.3c03670.s001
https://figshare.com/articles/journal_contribution/Synthesis_X_ray_Crystal_Structure_and_Antimicrobial_Studies_of_New_Quinazolin-4_3_i_H_i_one_Derivatives_Containing_the_1_2_4-Triazolo_3_4_i_b_i_1_3_4_thiadiazole_Moiety_and_4_Piperidinyl_Linker/24712410

المؤلفون: Ziyi Zhang (4269196), Jin Wang (29560), Shenghai Guo (1490353), Jing Fan (149601), Xuesen Fan (808785)

مصطلحات موضوعية: Biochemistry, Medicine, Biotechnology, Mental Health, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, broad substrate scope, high yields via, >)- one derivatives, exclusive 6 -<, phthalazinoquinazolinone derivatives, high regio, 2 -<, well tolerated, report herein, quinazolinone substrates, present protocol, practical strategy, functionalized quinazolinones, cyclization process, corresponding products, catalyzed regio, >‑ buok, >] quinazolin, >- phthalazino, >- buok

Relation: https://figshare.com/articles/journal_contribution/_i_t_i_BuOK-Catalyzed_Regio-_and_Stereoselective_Intramolecular_Hydroamination_Reaction_Leading_to_Phthalazinoquinazolinone_Derivatives/21805404

الاتاحة: https://doi.org/10.1021/acs.joc.2c02638.s001

المؤلفون: Wassim El Kayal, Hanna Severina, Vadim Tsyvunin, Sergiy Zalevskyi, Sergiy Shtrygol', Sergiy Vlasov, Olga Golovchenko, Sergiy Kovalenko, Victoriya Georgiyants

المصدر: ScienceRise: Pharmaceutical Science, 1(35), 58-69, (2022-02-28)

مصطلحات موضوعية: synthesis, quinazolin, benzyl, docking, GABA, anticonvulsant activity

Relation: oai:zenodo.org:6374078

الاتاحة: https://doi.org/10.15587/2519-4852.2022.253554

المؤلفون: Binghan Pang (10572996), Yangyang Wang (642852), Liqiang Hao (8984999), Gaorong Wu (6742973), Zhihong Ma (762189), Yafei Ji (6658016)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Molecular Biology, Biotechnology, Developmental Biology, Mental Health, Space Science, Chemical Sciences not elsewhere classified, two diverse structures, several control experiments, >)- one derivatives, oh )< sub, 2 ‑ arylquinazolinones, 2 , h <, gem <, b <, 2 -<, wide range, sequential annulation, respectively synthesized, plausible mechanism, efficient method, >] quinazolin, >- difluorostyrenes

Relation: https://figshare.com/articles/journal_contribution/Tandem_C_C_C_N_Bond_Formation_via_Rh_III_-Catalyzed_Fluoroalkenylation_and_Sequential_Annulation_of_2_Arylquinazolinones_and_i_gem_i_-Difluorostyrenes/21777690

الاتاحة: https://doi.org/10.1021/acs.joc.2c02006.s001

المؤلفون: Kayal, W. E. (Wassim), Severina, H. (Hanna), Tsyvunin, V. (Vadim), Zalevskyi, S. (Sergiy), Shtrygol’, S. (Sergiy), Vlasov, S. (Sergiy), Golovchenko, O. (Olga), Kovalenko, S. (Sergiy), Georgiyants, V. (Victoriya)

المصدر: ScienceRise: Pharmaceutical Science

مصطلحات موضوعية: synthesis, протисудомна активність, хиназолин, докинг, quinazolin, benzyl, docking, GABA, Indonesia, синтез, хіназолін, бензил, докінг, ГАМК, противосудорожная активность, anticonvulsant activity

وصف الملف: application/pdf

Relation: https://www.neliti.com/publications/530786/synthesis-and-anticonvulsant-activity-evaluation-of-n-24-dichlorophenylmethyl-2

الاتاحة: https://www.neliti.com/publications/530786/synthesis-and-anticonvulsant-activity-evaluation-of-n-24-dichlorophenylmethyl-2

المؤلفون: Sudershan R. Gondi (11881172), Althaf Shaik (5954912), Kenneth D. Westover (1349343)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Genetics, Molecular Biology, Pharmacology, Biotechnology, Ecology, Inorganic Chemistry, Chemical Sciences not elsewhere classified, involve environmental hazards, current synthetic methods, bioactive small molecules, medicinal chemistry quinazolin, substituted quinazolin, medicinal uses, wide variety, uniformly scalable, take advantage, situ <, several categories, secondary amides, n <, iasas )), dione -<, core scaffolds, acidic conditions, >- 3

Relation: https://figshare.com/articles/journal_contribution/Acid-Catalyzed_Synthesis_of_Isatoic_Anhydride-8-Secondary_Amides_Enables_IASA_Transformations_for_Medicinal_Chemistry/17696759

الاتاحة: https://doi.org/10.1021/acs.joc.1c02036.s001

المؤلفون: Juan A. De La Cruz (11154187), Thota Ganesh (1319988), Becky A. Diebold (11154190), Weiping Cao (2512747), Amelia Hofstetter (11154193), Neetu Singh (317211), Amrita Kumar (1846411), James McCoy (2512744), Priya Ranjan (177445), Susan M. E. Smith (11154196), Suryaprakash Sambhara (143793), J. David Lambeth (554606), Shivaprakash Gangappa (19763)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Physiology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, influenza, MIP, virus-induced cell death, Bcl -2 phosphorylation, virus-induced reactive oxygen species, cell survival Superoxide radicals, TG 6-44, pro-inflammatory mediators, IFN, PI, percent cells, Quinazolin-derived myeloperoxidase ., reactive oxygen species, IL, lung monocytic cells, PBMC, virus-induced inflammation, Annexin V, novel quinazolin-derived myeloperox.

Relation: https://figshare.com/articles/journal_contribution/Gene_expression_of_key_cell_survival_and_cell_death_associated_molecules_in_THP-1_cells_infected_with_A_X31_/15017065

الاتاحة: https://doi.org/10.1371/journal.pone.0254632.s004

المؤلفون: Juan A. De La Cruz (11154187), Thota Ganesh (1319988), Becky A. Diebold (11154190), Weiping Cao (2512747), Amelia Hofstetter (11154193), Neetu Singh (317211), Amrita Kumar (1846411), James McCoy (2512744), Priya Ranjan (177445), Susan M. E. Smith (11154196), Suryaprakash Sambhara (143793), J. David Lambeth (554606), Shivaprakash Gangappa (19763)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Physiology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, influenza, MIP, virus-induced cell death, Bcl -2 phosphorylation, virus-induced reactive oxygen species, cell survival Superoxide radicals, TG 6-44, pro-inflammatory mediators, IFN, PI, percent cells, Quinazolin-derived myeloperoxidase ., reactive oxygen species, IL, lung monocytic cells, PBMC, virus-induced inflammation, Annexin V, novel quinazolin-derived myeloperox.

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/15017068

الاتاحة: https://doi.org/10.1371/journal.pone.0254632.s005

المؤلفون: Ariadna Fernández (1638028), José Luis Díaz (1638049), Mónica García (8086490), Sergi Rodríguez-Escrich (2429539), Adriana Lorente (1457980), Raquel Enrech (1960390), Albert Dordal (10151778), Enrique Portillo-Salido (1859692), Mónica Porras (11524377), Begoña Fernández (2343823), Raquel F. Reinoso (1960381), José Miguel Vela (1638055), Carmen Almansa (1638043)

مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Science Policy, Chemical Sciences not elsewhere classified, showed high selectivity, reduce lipophilicity provided, pyrido ­[ 4, micromolar hts hit, improved analgesic efficacy, gated calcium channels, small alkyl group, piperazinyl bicyclic derivatives, 4 ­( 3, 4 -( 3, >)- one scaffold, v , 1 versus ca, >)- one, central scaffold, butyl group, position 3, 3 -<, selective ligands, safety ratio, r <, probably linked, piperazinyl quinazolin, pharmacological activities, new series

Relation: https://figshare.com/articles/journal_contribution/Piperazinyl_Bicyclic_Derivatives_as_Selective_Ligands_of_the_2_1_Subunit_of_Voltage-Gated_Calcium_Channels/16744425

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00416.s001

المؤلفون: Subrata Sahoo (10190507), Shantanu Pal (2413069)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Ecology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, wide substrate scope, catalyzed nitrile formation, 2 ‑ nitrobenzaldehydes, nitrile formation, catalyzed one, via <, sole oxidant, nitro group, natural products, hydrazine hydrate, h <, first time, economical approach, atmospheric oxygen, application toward, >]­ quinazolin, 3 -<

Relation: https://figshare.com/articles/journal_contribution/Copper-Catalyzed_One-Pot_Synthesis_of_Quinazolinones_from_2_Nitrobenzaldehydes_with_Aldehydes_Application_toward_the_Synthesis_of_Natural_Products/17072578

الاتاحة: https://doi.org/10.1021/acs.joc.1c02343.s001

المؤلفون: Kavitha, K¹, Yahoob, Nehla, Vijayakumar, B, Fathima, K Reshma

المصدر: Asian Journal of Research in Chemistry 10(4):577-581. 2017

المؤلفون: Mostafa M. Ghorab, Mansour S. Alsaid, Aiten M. Soliman, Abdullah A. Al-Mishari

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 67-73 (2018)

مصطلحات موضوعية: Benzo[g]quinazolin, benzenesulfonamide, EGFR, HER2, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/c645a93ffe1b4479975b2a5533a3a428

المؤلفون: Rishipathak, D. D.¹, Kokate, A. B., Madhawai, K. S.

المصدر: Asian Journal of Research in Pharmaceutical Science 7(4):209-211. 2017

المؤلفون: Mostafa M. Ghorab, Mansour S. Alsaid, Aiten M. Soliman, Fatma A. Ragab

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 893-907 (2017)

مصطلحات موضوعية: Benzo[g]quinazolin, sulfonamide, VEGFR-2 inhibitors, apoptosis, breast cancer, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/14ac69073543458d907631eaa1f699ea

المؤلفون: Nataliya А. Zhukova, Vakhid А. Mamedov, Milyausha S. Kadyrova

المصدر: Chemistry of Heterocyclic Compounds

مصطلحات موضوعية: imidazo[1,2-a]pyrimidines, 010405 organic chemistry, Chemistry, Organic Chemistry, pyrazolo[3,4-d]pyrimidines, thieno[2,3-d]pyrimidines, 010402 general chemistry, 01 natural sciences, Dimroth rearrangement, Article, 0104 chemical sciences, [1,2,4]triazolo[1,5-a]pyrimidines, pyrrolo[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines, furo[2,3-d]pyrimidines, antiviral activity, Organic chemistry, purines, quinazolin(on)es

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05eb9713b042c0a81dcf9bafebed428
https://doi.org/10.1007/s10593-021-02913-7

المصدر: ScienceRise: Pharmaceutical Science; No. 1(35) (2022); 58-69
ScienceRise: Pharmaceutical Science; № 1(35) (2022); 58-69

مصطلحات موضوعية: synthesis, хиназолин, quinazolin, протисудомна активність, GABA, синтез, противосудорожная активность, docking, бензил, anticonvulsant activity, докинг, benzyl, хіназолін, докінг, ГАМК

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=scientific_p::e7c843e9dc30bdb3226b5ef3a059b092
http://journals.uran.ua/sr_pharm/article/view/253554

المؤلفون: Juan A. De La Cruz (11154187), Thota Ganesh (1319988), Becky A. Diebold (11154190), Weiping Cao (2512747), Amelia Hofstetter (11154193), Neetu Singh (317211), Amrita Kumar (1846411), James McCoy (2512744), Priya Ranjan (177445), Susan M. E. Smith (11154196), Suryaprakash Sambhara (143793), J. David Lambeth (554606), Shivaprakash Gangappa (19763)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Physiology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, influenza, MIP, virus-induced cell death, Bcl -2 phosphorylation, virus-induced reactive oxygen species, cell survival Superoxide radicals, TG 6-44, pro-inflammatory mediators, IFN, PI, percent cells, Quinazolin-derived myeloperoxidase ., reactive oxygen species, IL, lung monocytic cells, PBMC, virus-induced inflammation, Annexin V, novel quinazolin-derived myeloperox.

Relation: https://figshare.com/articles/figure/TG6-44_treatment_does_not_enhance_cytotoxicity_in_uninfected_THP-1_cells_/15017053

الاتاحة: https://doi.org/10.1371/journal.pone.0254632.s001