المؤلفون: Anqi Sun, Wen-Xiong Wang

مصطلحات موضوعية: Medicine, Ecology, Developmental Biology, Inorganic Chemistry, Plasma Physics, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, zinc oxide nanoparticles, different roles played, inhibited larval growth, damaged larval guts, reducing gut dissolution, whereas smps mitigated, 32 resisted phototransformation, vivo dissolution, larval development, vivo transformation, surfaced si, significant effect, poorly understood, n <, marine organisms, marine animals, lower concentration, ionic zn, higher concentration, growing concern, findings revealed

Relation: https://figshare.com/articles/journal_contribution/Reducing_Gut_Dissolution_of_Zinc_Oxide_Nanoparticles_by_Secondary_Microplastics_with_Consequent_Impacts_on_Barnacle_Larvae/24977307

الاتاحة: https://doi.org/10.1021/acs.est.3c07869.s001
https://figshare.com/articles/journal_contribution/Reducing_Gut_Dissolution_of_Zinc_Oxide_Nanoparticles_by_Secondary_Microplastics_with_Consequent_Impacts_on_Barnacle_Larvae/24977307

المؤلفون: Diebold, Steffen M.

مصطلحات موضوعية: ddc:500, ddc:530, ddc:540, ddc:610, in vivo hydrodynamics, omnivores, malabsorption, human intestine, chyme volume, liquid-solid meal, release kinetics, gastrointestinal motility, Sherwood, Prandtl, boundary layer separation, saturation solubility, canine intestine, flow pattern, microparticles, convective diffusion, particle size, caloric liquids, stirring, paddle, basket, in vivo dissolution, laminar, turbulent, particle-liquid Reynolds number, dissipation

وصف الملف: application/pdf

Relation: https://oa.tib.eu/renate/handle/123456789/14109; https://doi.org/10.34657/13139

الاتاحة: https://oa.tib.eu/renate/handle/123456789/14109
https://doi.org/10.34657/13139

المؤلفون: Christian Jede, Laura J. Henze, Kirstin Meiners, Malte Bogdahn, Marcel Wedel, Valeria van Axel

المصدر: Pharmaceutics; Volume 15; Issue 4; Pages: 1069

مصطلحات موضوعية: in vitro dissolution testing, in vitro dissolution methods, in vivo dissolution, oral drug absorption, oral bioavailability, gastrointestinal

وصف الملف: application/pdf

Relation: Biopharmaceutics; https://dx.doi.org/10.3390/pharmaceutics15041069

الاتاحة: https://doi.org/10.3390/pharmaceutics15041069

المؤلفون: Yinqian Yang, Yongjiu Lv, Chengying Shen, Tingting Shi, Haisheng He, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu, Wei Wu

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 4, Pp 1056-1068 (2021)

مصطلحات موضوعية: In vivo dissolution, Fenofibrate, Fluorescence, Aggregation-caused quenching, Bioimaging, IVIVC, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383520306717; https://doaj.org/toc/2211-3835

URL الوصول: https://doaj.org/article/b9d45f80cb5445a1a8fb1af80e2f041d

المؤلفون: Figueroa-Campos, Andrés, Sánchez-Dengra, Bárbara, Merino, Virginia, Dahan, Arik, Gonzalez-Alvarez, Isabel, García-Arieta, Alfredo, Gonzalez-Alvarez, Marta, Bermejo, Marival

المساهمون: European Regional Development Fund, Ministerio de Ciencia, Innovación y Universidades, Ministerio de Economía, Industria y Competitividad

مصطلحات موضوعية: Candesartan cilexetil, IVIVC, Bioequivalence, BCS, Predictive in vivo-dissolution

Relation: Pharmaceutics; info:eu-repo/grantAgreement/MCIU//FPU17%2F00530/; info:eu-repo/grantAgreement/MINECO//SAF2016-78756/; https://doi.org/10.3390/pharmaceutics12070633; http://hdl.handle.net/10251/192980; urn:eissn:1999-4923; PMC7408357

الاتاحة: http://hdl.handle.net/10251/192980
https://doi.org/10.3390/pharmaceutics12070633

المؤلفون: Hens, Bart, Sinko, Patrick, Job, Nicholas, Dean, Meagan, Al-Gousous, Jozef, Salehi, Niloufar, Ziff, Robert M., Tsume, Yasuhiro, Bermejo, Marival, Paixao, Paulo, Brasseur, James G., Yu, Alex, Talattof, Arjang, Benninghoff, Gail, Langguth, Peter, Lennernas, Hans, Hasler, William L., Marciani, Luca, Dickens, Joseph, Shedden, Kerby, Sun, Duxin, Amidon, Gregory E., Amidon, Gordon L.

مصطلحات موضوعية: In vivo dissolution, Bioequivalence, Bioavailability, Oral absorption, MRI, Manometry, Computational fluid dynamics

Relation: https://nottingham-repository.worktribe.com/output/949875; International Journal of Pharmaceutics; Volume 548; Issue 1; https://nottingham-repository.worktribe.com/file/949875/1/In%20Vivo%20Predictive%20Dissolution_accepted.pdf

الاتاحة: https://doi.org/10.1016/j.ijpharm.2018.06.050
https://nottingham-repository.worktribe.com/file/949875/1/In%20Vivo%20Predictive%20Dissolution_accepted.pdf
https://nottingham-repository.worktribe.com/output/949875

المؤلفون: Duxin Sun, Bo Wen, Bart Hens, Jianghong Fan, Gregory E. Amidon, Joseph Dickens, Allen Lee, Gail Benninghoff, Marival Bermejo, Gordon L. Amidon, Jeffrey Wysocki, Paulo Paixão, Raimar Löbenberg, William L. Hasler, Arjang Talattof, Niloufar Salehi, Jason Baker, Alex Yu, Robert Lionberger, Yasuhiro Tsume, Ann Frances, Mark J. Koenigsknecht, Kerby Shedden

المصدر: Mol Pharm

مصطلحات موضوعية: Male, BIOAVAILABILITY, Administration, Oral, Datasets as Topic, Pharmaceutical Science, Ibuprofen, 02 engineering and technology, Research & Experimental Medicine, buffer capacity, Pharmacology, 030226 pharmacology & pharmacy, Food-Drug Interactions, CALORIC CONTENT, 0302 clinical medicine, Oral administration, oral absorption, Drug Discovery, ABSORPTION, VITRO, Pharmacology & Pharmacy, IN-VIVO DISSOLUTION, ibuprofen, Biological Variation, Individual, Stomach, immediate release, Hydrogen-Ion Concentration, Middle Aged, Postprandial Period, 021001 nanoscience & nanotechnology, Healthy Volunteers, Postprandial, Medicine, Research & Experimental, Area Under Curve, Molecular Medicine, Female, MEAL, 0210 nano-technology, Life Sciences & Biomedicine, Tablets, medicine.drug, Adult, in vivo dissolution, Cmax, Biological Availability, Bioequivalence, Models, Biological, DOSAGE FORMS, Article, in vivo study, Young Adult, 03 medical and health sciences, Pharmacokinetics, In vivo, MOTILITY, medicine, Humans, Computer Simulation, Gastric Absorption, bioequivalence, Science & Technology, business.industry, manometry, fed state, Bioavailability, Drug Liberation, Biological Variation, Population, Gastric Emptying, Solubility, LIQUIDS, local drug concentration in the GI tract, business, TRACT

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75464368c0204b96e56e4906562616a3
https://doi.org/10.1021/acs.molpharmaceut.8b00736

المؤلفون: Isabel González-Álvarez, Marival Bermejo, Virginia Merino, Andrés Figueroa-Campos, Marta González-Álvarez, Arik Dahan, Bárbara Sánchez-Dengra, Alfredo García-Arieta

المصدر: Pharmaceutics, Vol 12, Iss 633, p 633 (2020)
Pharmaceutics
Volume 12
Issue 7

مصطلحات موضوعية: Chromatography, genetic structures, Chemistry, Pharmaceutical Science, lcsh:RS1-441, Time scaling, Bioequivalence, BCS, Article, Candesartan cilexetil, lcsh:Pharmacy and materia medica, Candesartan, IVIVC, In vivo, medicine, Predictive in vivo-dissolution, In vitro in vivo, Solubility, Dissolution, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d364c5b9cefb6593da62615dcdc6b44d
https://hdl.handle.net/10251/192980

المؤلفون: Yasuhiro Tsume, William L. Hasler, Gail Benninghoff, Paulo Paixão, Gordon L. Amidon, Gregory E. Amidon, Joseph Dickens, Duxin Sun, Bo Wen, Naír Rodríguez-Hornedo, Allen Lee, Jianghong Fan, Raimar Löbenberg, Marival Bermejo, Jason Baker, Katie L. Cavanagh, Kerby Shedden, Niloufar Salehi, Alex Yu, Arjang Talattof, Mark J. Koenigsknecht, Ann Frances, Gislaine Kuminek, Robert Lionberger, Bart Hens, Jeffrey Wysocki

المصدر: Mol Pharm

مصطلحات موضوعية: Male, PHARMACOKINETICS, WEAK ACID, Administration, Oral, Datasets as Topic, Pharmaceutical Science, Ibuprofen, 02 engineering and technology, Pharmacology, Research & Experimental Medicine, 030226 pharmacology & pharmacy, 0302 clinical medicine, Oral administration, Drug Discovery, Healthy volunteers, Medicine, Pharmacology & Pharmacy, DRUG, IN-VIVO DISSOLUTION, ibuprofen, Biological Variation, Individual, ORAL ABSORPTION, Fasting, Hydrogen-Ion Concentration, Middle Aged, immediate release, 021001 nanoscience & nanotechnology, Healthy Volunteers, Pharmacokinetic analysis, Fasted state, Medicine, Research & Experimental, motility, Area Under Curve, Molecular Medicine, Female, 0210 nano-technology, Life Sciences & Biomedicine, Tablets, medicine.drug, Adult, in vivo dissolution, Biological Availability, SIMULATOR, Bioequivalence, Models, Biological, Article, Young Adult, 03 medical and health sciences, Humans, bioequivalence, Science & Technology, business.industry, aspiration/motility study, organic chemicals, Plasma levels, manometry, PANCREATIC-SECRETION, Bioavailability, Gastrointestinal Tract, Drug Liberation, Biological Variation, Population, Solubility, Gastrointestinal Absorption, local drug concentration in the GI tract, MIGRATING MOTOR COMPLEX, business, bioavailability

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f8941f706f1fba91a3eab29c093bb9
https://lirias.kuleuven.be/handle/123456789/647959

المؤلفون: Gordon L. Amidon, Bart Hens, Gail Benninghoff, Jozef Al-Gousous, Duxin Sun, Yasuhiro Tsume, William L. Hasler, Hans Lennernäs, Patrick D. Sinko, Arjang Talattof, Paulo Paixão, Alex Yu, James G. Brasseur, Meagan Dean, Luca Marciani, Gregory E. Amidon, Joseph Dickens, Kerby Shedden, Robert M. Ziff, Nicholas Job, Niloufar Salehi, Marival Bermejo, Peter Langguth

المصدر: Int J Pharm

مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Bioavailability, Computer science, Manometry, Drug Compounding, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Bioequivalence, Computational fluid dynamics, 030226 pharmacology & pharmacy, Article, DOSAGE FORMS, INDUCED VARIABILITY, 03 medical and health sciences, 0302 clinical medicine, BIOPHARMACEUTICS CLASSIFICATION-SYSTEM, ABSORPTION, Humans, Dissolution testing, Oral absorption, Pharmacology & Pharmacy, Dissolution, IN-VIVO DISSOLUTION, In vivo dissolution, Science & Technology, WORKSHOP REPORT, United States Food and Drug Administration, business.industry, GASTROINTESTINAL SIMULATOR GIS, VITRO DISSOLUTION, 021001 nanoscience & nanotechnology, Biopharmaceutics Classification System, United States, MODEL, Drug Liberation, New product development, Predictive power, DIFFUSION-CONTROLLED DISSOLUTION, Biochemical engineering, 0210 nano-technology, business, Life Sciences & Biomedicine, Oral retinoid, MRI

وصف الملف: PDF; Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1e374101cfeaeedc293ed4015d7050

المؤلفون: William L. Hasler, Ann Frances, Gregory E. Amidon, Joseph Dickens, Alex Yu, Jeffrey Wysocki, Paulo Paixão, Jianghong Fan, Bo Wen, Gail Benninghoff, Raimar Löbenberg, Bart Hens, Allen Lee, Marival Bermejo, Niloufar Salehi, Yasuhiro Tsume, Arjang Talattof, Robert Lionberger, Kerby Shedden, Gordon L. Amidon, Mark J. Koenigsknecht, Jason Baker, Duxin Sun

المصدر: Eur J Pharm Biopharm

مصطلحات موضوعية: Male, INDICATORS, Bioavailability, Paromomycin, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Phenolsulfonphthalein, chemistry.chemical_compound, 0302 clinical medicine, Intestine, Small, ABSORPTION, VITRO, Pharmacology & Pharmacy, Antrum, IN-VIVO DISSOLUTION, In vivo dissolution, ORAL DOSAGE FORMS, Bioequivalence, Phenol red, Stomach, digestive, oral, and skin physiology, Fasting, General Medicine, Middle Aged, Postprandial Period, 021001 nanoscience & nanotechnology, Healthy Volunteers, medicine.anatomical_structure, Female, 0210 nano-technology, Life Sciences & Biomedicine, Nonabsorbable marker, Biotechnology, Adult, Gastrointestinal, Human gastric emptying, POORLY ABSORBABLE DRUG, Models, Biological, Article, Aspiration/motility study, Young Adult, 03 medical and health sciences, HUMAN GASTROINTESTINAL-TRACT, Pharmacokinetics, Gastrointestinal mass transport model, MOTILITY, medicine, Humans, Oral absorption, Migrating motor complex, Science & Technology, Gastric emptying, Small intestine, MODEL, Gastric Emptying, Intestinal Absorption, Solubility, chemistry, Duodenum

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3544b87417b4b0f484d451483faf10
https://lirias.kuleuven.be/handle/123456789/647949

المؤلفون: Jennifer B. Dressman, Rodrigo Cristofoletti, Nikunjkumar Patel, Valvanera Vozmediano Esteban, Bart Hens, Stephan Schmidt

مصطلحات موضوعية: Chemistry, Pharmaceutical, Chemistry, Multidisciplinary, Administration, Oral, Pharmaceutical Science, dissolution, Ibuprofen, Chemistry, Medicinal, 02 engineering and technology, 030226 pharmacology & pharmacy, 0302 clinical medicine, Pharmacology & Pharmacy, IN-VIVO DISSOLUTION, media_common, Chemistry, ORAL ABSORPTION, particle size, 021001 nanoscience & nanotechnology, mechanistic modeling, BUFFER CAPACITY, Product (mathematics), Physical Sciences, SIMULATION, Drug product, 0210 nano-technology, Biological system, Life Sciences & Biomedicine, physiologically based pharmacokinetic (PBPK) modeling, medicine.drug, Adult, Drug, media_common.quotation_subject, Models, Biological, DOSAGE FORMS, 03 medical and health sciences, Drug Development, Pharmacokinetics, medicine, Humans, Immediate release, Particle Size, RELEASE, Science & Technology, KETOCONAZOLE, Gastrointestinal Tract, MODEL, Drug Liberation, Solubility, Particle size, absorption, in vitro-in vivo (IVIVC) correlation(s)

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcb5ca1f140cf05bff5e4dc6520f8c9
https://lirias.kuleuven.be/handle/123456789/647951

المؤلفون: Raimar Löbenberg, Divyakant Desai, Amitava Mitra, Marival Bermejo, Bart Hens, Dakshina Murthy Chilukuri, Pablo M. González, Maura Corsetti, Alexis Aceituno

المصدر: The AAPS journal. 21(4)

مصطلحات موضوعية: Drug, formulation prediction, Computer science, media_common.quotation_subject, Fixed-dose combination, Pharmaceutical Science, Administration, Oral, Pharmacy, Bioequivalence, 030226 pharmacology & pharmacy, PHARMACEUTICAL EXCIPIENTS, Dosage form, 03 medical and health sciences, fixed dose combination drug products, 0302 clinical medicine, in vivo predictions, INTESTINAL PERMEABILITY, Drug Development, IN-VITRO METHODOLOGY, ABSORPTION, Humans, Pharmacology & Pharmacy, DRUG, WEAK BASES, media_common, Active ingredient, bioequivalence, Science & Technology, business.industry, Gastrointestinal Physiology, Congresses as Topic, MODEL, Drug Combinations, Risk analysis (engineering), Pharmaceutical Preparations, Gastrointestinal Absorption, 030220 oncology & carcinogenesis, New product development, gastrointestinal physiology, MIGRATING MOTOR COMPLEX, IMMEDIATE-RELEASE, business, Life Sciences & Biomedicine, VIVO DISSOLUTION, Tablets

وصف الملف: Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34411c89d83fd9b5a7d9901c03147a2f
https://pubmed.ncbi.nlm.nih.gov/31172358

المؤلفون: Hidehumi HAYASHI, Kuniaki ISHII, Shigeru ITAI, Yoko KATAYAMA, Yuji ITO

المصدر: Biological and Pharmaceutical Bulletin. 1995, 18(6):882

المؤلفون: Gregory E. Amidon, Alfredo García-Arieta, Naír Rodríguez-Hornedo, Marival Bermejo, Alejandro Ruiz-Picazo, Yasuhiro Tsume, Jozef Al-Gousous, Deanna M. Mudie, Bart Hens, Gordon L. Amidon, Isabel González-Álvarez, Gislaine Kuminek

المصدر: Pharmaceutics, Vol 11, Iss 3, p 122 (2019)
Pharmaceutics
Volume 11
Issue 3

مصطلحات موضوعية: liquid–liquid phase separation, SALT DISPROPORTIONATION, gastrointestinal absorption, Sodium, lcsh:RS1-441, Pharmaceutical Science, Excipient, chemistry.chemical_element, Salt (chemistry), Hydrochloric acid, SOLUBILITY, Calcium, Bioequivalence, Article, lcsh:Pharmacy and materia medica, chemistry.chemical_compound, FLUIDS, EMA, oral absorption, ABSORPTION, medicine, Pharmacology & Pharmacy, SUPERSATURATED SOLUTIONS, dexketoprofen, Simulation, chemistry.chemical_classification, Science & Technology, Chemistry, liquid-liquid phase separation, Phosphate, Dexketoprofen, SIMILARITIES, gastrointestinal simulator, in vitro dissolution, IN-VITRO DISSOLUTION, Life Sciences & Biomedicine, VIVO DISSOLUTION, METHODOLOGY, microscopy imaging, medicine.drug

وصف الملف: application/pdf; Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51068b1dcd345bc24a0581e147306ec3
https://doi.org/10.3390/pharmaceutics11030122

المؤلفون: Diebold, Steffen M.

مصطلحات موضوعية: in vivo hydrodynamics, in vivo dissolution, laminar, turbulent, particle-liquid Reynolds number, Sherwood, Prandtl, eddies, dissipation, energy cascade, boundary layer separation, convective diffusion, saturation solubility, kinematic viscosity, particle size, particle morphology, surface roughness, microparticles, flow pattern, stirring, paddle, basket, fluid velocity

Time: 500, 530, 540, 570, 590, 610, 630

وصف الملف: application/pdf

Relation: http://hdl.handle.net/10900/147222; http://dx.doi.org/10.15496/publikation-88563; http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-1472228

الاتاحة: http://hdl.handle.net/10900/147222
https://doi.org/10.15496/publikation-88563
http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-1472228

المؤلفون: Norma R. Sperandeo, Diego Enrique Kassuha, Flavia Paola Bruno, Virginia Aiassa, Gabriel R. Cuadra

مصطلحات موضوعية: Male, Disk intrinsic/in vivo dissolution rates, Anti-Inflammatory Agents, Pharmaceutical Science, Drug Stability, X-Ray Diffraction, Pregnenediones, medicine, Animals, Rats, Wistar, Polymorphism, Glucocorticoids, Calorimetry, Differential Scanning, Chemistry, Deflazacort, Otras Ciencias Químicas, Ciencias Químicas, General Medicine, Molecular biology, Crystallography, Powder X-ray diffractometry, Solubility, Crystallization, Glucocorticoid, CIENCIAS NATURALES Y EXACTAS, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2ba08850a98916ff7f81c0cf04838d
http://www.tandfonline.com/doi/full/10.3109/10837450.2013.871033

المؤلفون: Kassuha, Diego Enrique, Aiassa, Virginia, Bruno, Flavia Paola, Cuadra, Gabriel R., Sperandeo, Norma Rebeca

مصطلحات موضوعية: Crystallization, Deflazacort, Disk Intrinsic/In Vivo Dissolution Rates, Polymorphism, Powder X-Ray Diffractometry, https://purl.org/becyt/ford/1.4, https://purl.org/becyt/ford/1

وصف الملف: application/pdf

Relation: http://hdl.handle.net/11336/25277; Kassuha, Diego Enrique; Aiassa, Virginia; Bruno, Flavia Paola; Cuadra, Gabriel R.; Sperandeo, Norma Rebeca; Preparation and characterization of polymorphs of the glucocorticoid deflazacort; Taylor & Francis; Pharmaceutical Development and Technology; 20; 4; 1-2014; 401-409; CONICET Digital; CONICET

الاتاحة: http://hdl.handle.net/11336/25277

المؤلفون: Sheng, Jie

المساهمون: Amidon, Gordon L., Rodriguez-Hornedo, Nair, Schwendeman, Steven P., Wang, Henry Yee-Neen

مصطلحات موضوعية: In Vitro Dissolution, In Vivo Dissolution, Hydrodynamics, Buffer Effects, Bioequivalence, Pharmacy and Pharmacology, Health Sciences

وصف الملف: 1373 bytes; 2523907 bytes; text/plain; application/pdf

Relation: https://hdl.handle.net/2027.42/57668

الاتاحة: https://hdl.handle.net/2027.42/57668

المؤلفون: Scripsick, R. C., Crist, K. C., Tillery, M. I., Soderholm, S. C., Rothenberg, S. J.

المساهمون: LOS ALAMOS NATIONAL LAB NM

المصدر: DTIC AND NTIS

مصطلحات موضوعية: Physical Chemistry, DEPLETED URANIUM, URANIUM, AEROSOLS, HAZARDS, PENETRATION, EXPOSURE(PHYSIOLOGY), PHYSICOCHEMICAL PROPERTIES, EQUATIONS, INHALATION, DISSOLUTION ANALYSIS, OXIDE AEROSOLS, LUNG FLUIDS, RESPIRABLE FRACTION, IN VIVO DISSOLUTION, IN VITRO DISSOLUTION, YELLOW CAKE SAMPLES, URANIUM OXIDE, PE28030F, WUAFATL2708GC03

وصف الملف: text/html

Relation: http://www.dtic.mil/docs/citations/ADA152274

الاتاحة: http://www.dtic.mil/docs/citations/ADA152274
http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA152274