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1Academic Journal
المؤلفون: Jie Yang, Vladimir O. Talibov, Stefan Peintner, Claire Rhee, Vasanthanathan Poongavanam, Matthis Geitmann, Matteo Rossi Sebastiano, Bernd Simon, Janosch Hennig, Doreen Dobritzsch, U. Helena Danielson, Jan Kihlberg
المصدر: ACS Omega, Vol 5, Iss 8, Pp 3979-3995 (2020)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2470-1343
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2Academic Journal
المؤلفون: Annika Rogstam, Maria Nyblom, Signe Christensen, Celeste Sele, Vladimir O. Talibov, Therese Lindvall, Anna Andersson Rasmussen, Ingemar André, Zoë Fisher, Wolfgang Knecht, Frank Kozielski
المصدر: International Journal of Molecular Sciences; Volume 21; Issue 19; Pages: 7375
مصطلحات موضوعية: SARS CoV-2, COVID-19, non-structural proteins, nsp10, replication–transcription complex, RNA capping machinery
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Biochemistry; https://dx.doi.org/10.3390/ijms21197375
الاتاحة: https://doi.org/10.3390/ijms21197375
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المؤلفون: Doreen Dobritzsch, Daniela Cederfeldt, Daniele Tedesco, Martin J. Talu, Alberto Del Rio, Xavier Barril, Marina Naldi, Giovanna Forte, Paola Sanese, Edoardo Fabini, Vladimir O. Talibov, Elisabetta Manoni, Martina Lepore Signorile, Manuela Bartolini, Moira Rachman, Edward A. FitzGerald, U. Helena Danielson, Cristiano Simone, Filip Mihalic
المساهمون: Talibov, Vladimir O, Fabini, Edoardo, FitzGerald, Edward A, Tedesco, Daniele, Cederfeldt, Daniela, Talu, Martin J, Rachman, Moira M, Mihalic, Filip, Manoni, Elisabetta, Naldi, Marina, Sanese, Paola, Forte, Giovanna, Lepore Signorile, Martina, Barril, Xavier, Simone, Cristiano, Bartolini, Manuela, Dobritzsch, Doreen, Del Rio, Alberto, Danielson, U Helena
المصدر: ChemBioChem (Internet) 22 (2021). doi:10.1002/cbic.202000736
info:cnr-pdr/source/autori:Talibov, Vladimir O.; Fabini, Edoardo; FitzGerald, Edward A.; Tedesco, Daniele; Cederfeldt, Daniela; Talu, Martin J.; Rachman, Moira M.; Mihalic, Filip; Manoni, Elisabetta; Naldi, Marina; Sanese, Paola; Forte, Giovanna; Lepore Signorile, Martina; Barril, Xavier; Simone, Cristiano; Bartolini, Manuela; Dobritzsch, Doreen; Del Rio, Alberto; Danielson, U. Helena/titolo:Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase/doi:10.1002%2Fcbic.202000736/rivista:ChemBioChem (Internet)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:22
'ChemBioChem ', vol: 22, pages: 1597-1608 (2021)
Chembiochemمصطلحات موضوعية: Methyltransferase, Lysine, Drug Evaluation, Preclinical, Druggability, epigenetic enzyme, Plasma protein binding, Ligands, 01 natural sciences, Biochemistry, Piperidines, biophysical methods, chemistry.chemical_classification, SMYD3, Full Paper, biology, epigenetic enzymes, Stereoisomerism, Full Papers, Ligand (biochemistry), Hsp90, Biofysik, 3. Good health, Molecular Medicine, Allosteric Site, Protein Binding, Allosteric regulation, Biophysics, Molecular Dynamics Simulation, biophysical method, 010402 general chemistry, Cell Line, Tumor, Surface plasmon resonance, Humans, HSP90 Heat-Shock Proteins, diperodon, Molecular Biology, Binding Sites, Lysine methyl transferase, 010405 organic chemistry, screening, Organic Chemistry, Histone-Lysine N-Methyltransferase, 0104 chemical sciences, SMYD3 biology, Kinetics, Enzyme, chemistry, biology.protein, ligand discovery
وصف الملف: ELETTRONICO; application/pdf
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4Academic Journal
المؤلفون: Marco Daniele Parenti, Marina Naldi, Elisabetta Manoni, Edoardo Fabini, Daniela Cederfelt, Vladimir O. Talibov, Valeria Gressani, Ummu Guven, Valentina Grossi, Candida Fasano, Paola Sanese, Katia De Marco, Alexander A. Shtil, Alexander V. Kurkin, Andrea Altieri, U. Helena Danielson, Giuseppina Caretti, Cristiano Simone, Greta Varchi, Manuela Bartolini, Alberto Del Rio
المساهمون: Daniele Parenti, Marco, Naldi, Marina, Manoni, Elisabetta, Fabini, Edoardo, Cederfelt, Daniela, Talibov, Vladimir O., Gressani, Valeria, Guven, Ummu, Grossi, Valentina, Fasano, Candida, Sanese, Paola, DE MARCO, Katia, Shtil, Alexander A., Kurkin, Alexander V., Altieri, Andrea, Helena Danielson, U., Caretti, Giuseppina, Simone, Cristiano, Varchi, Greta, Bartolini, Manuela, Del Rio, Alberto
مصطلحات موضوعية: Covalent inhibitor, SMYD3, Lysine methyltransferase, Epigenetic inhibitor, Cancer target therapy
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000862667200009; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11573/1656399; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85138099182
الاتاحة: http://hdl.handle.net/11573/1656399
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المؤلفون: Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov, Duy Duc Vo, Dario Akaberi, Vladimir O. Talibov, Natalia Nekhotiaeva, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Janina Krambrich, Ali Tas, Bo Lundgren, Ylva Gravenfors, Alexander J. Craig, Yoseph Atilaw, Anja Sandström, Lindon W. K. Moodie, Åke Lundkvist, Martijn J. van Hemert, Johan Neyts, Johan Lennerstrand, Jan Kihlberg, Kristian Sandberg, U. Helena Danielson, Jens Carlsson
المصدر: Journal of the American Chemical Society, 144(7), 2905-2920. AMER CHEMICAL SOC
مصطلحات موضوعية: Infectious Medicine, SARS-CoV-2, Drug Evaluation, Preclinical, Infektionsmedicin, General Chemistry, Microbial Sensitivity Tests, Cysteine Proteinase Inhibitors, Biochemistry, Antiviral Agents, Catalysis, Molecular Docking Simulation, Small Molecule Libraries, Colloid and Surface Chemistry, Catalytic Domain, Chlorocebus aethiops, Microsomes, Liver, Animals, Humans, Vero Cells, Coronavirus 3C Proteases, Protein Binding
وصف الملف: Print-Electronic; application/pdf
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المؤلفون: Alberto Del Rio, Edoardo Fabini, Marina Naldi, Carlo Bertucci, Filip Mihalic, Vladimir O. Talibov, U. Helena Danielson, Manuela Bartolini
المساهمون: Fabini E., Talibov V.O., Mihalic F., Naldi M., Bartolini M., Bertucci C., Del Rio A., Danielson U.H.
المصدر: Biochemistry. 58:3634-3645
مصطلحات موضوعية: Methyltransferase, Protein Conformation, MAP3K2, Crystallography, X-Ray, Ligands, Biochemistry, Multitarget compounds Multi-target-directed ligands Acetylcholinesterase inhibitors Butyrylcholinesterase inhibitors NMDA antagonists Brain permeability, Epigenesis, Genetic, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Enzyme Stability, Escherichia coli, Humans, Structure–activity relationship, Epigenetics, Protein Unfolding, 030304 developmental biology, 0303 health sciences, MAP kinase kinase kinase, Chemistry, Circular Dichroism, Biochemistry and Molecular Biology, Temperature, Histone-Lysine N-Methyltransferase, Methylation, Small molecule, Kinetics, 030220 oncology & carcinogenesis, Thermodynamics, Biokemi och molekylärbiologi
وصف الملف: ELETTRONICO
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المؤلفون: Céleste Sele, Jiaqi Lou, Xinyue Shi, Maria Nyblom, Tobias Krojer, Vladimir O. Talibov, Zoë Fisher, Annika Rogstam, Qian Wang, Danni Dong, Frank Kozielski, Wolfgang Knecht
المصدر: RSC Chemical Biology
مصطلحات موضوعية: chemistry.chemical_classification, Microscale thermophoresis, RNA, Computational biology, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, Affinities, Small molecule, Chemistry, Enzyme, chemistry, Viral replication, Chemistry (miscellaneous), Exoribonuclease, Proofreading, Molecular Biology
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8
المؤلفون: Manfred S. Weiss, E. Jagudin, J. Wollenhaupt, G.M.A. Lima, L.S. Benz, Uwe Mueller, Costantino Marullo, T. Barthel, Vladimir O. Talibov
المصدر: Acta Crystallographica Section D Structural Biology
Acta Crystallographica. Section D, Structural Biologyمصطلحات موضوعية: Data Analysis, Models, Molecular, 0301 basic medicine, Macromolecular Substances, Computer science, Fragment-based lead discovery, Life Sciences Building Blocks of Life Structure and Function, 02 engineering and technology, Ligands, Bottleneck, drug discovery, 03 medical and health sciences, Software, Fragment (logic), Structural Biology, protein crystallography, Web application, Throughput (business), Focus (computing), business.industry, Proteins, fragment-based lead discovery, fragment screening, 021001 nanoscience & nanotechnology, Research Papers, Automation, high-throughput data analysis, Crystallography, 030104 developmental biology, 0210 nano-technology, business, 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften
وصف الملف: application/pdf
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9
المؤلفون: Ben Davis, Giulia Opassi, Darius Vagrys, U. Helena Danielson, Iwan J. P. de Esch, Anna Moberg, P. Boronat, Roderick E. Hubbard, Doreen Dobritzsch, Claes Holmgren, Jacqueline E. van Muijlwijk-Koezen, David J. Hamilton, Edward A. FitzGerald, Peter O'Brien, Daniela Cederfelt, Hanna F. Klein, Maikel Wijtmans, Vladimir O. Talibov, Mia Abramsson, Maria T. Lindgren
المساهمون: Innovations in Human Health & Life Sciences, AIMMS, Chemistry and Pharmaceutical Sciences, Medicinal chemistry
المصدر: bioRxiv, 2020. Cold Spring Harbor Laboratory Press
Fitzgerald, E, Hamilton, D, Boronat, P, van Muijlwijk-Koezen, J E, Wijtmans, M, de Esch, IJP & Danielson, H 2020, ' Multiplexed experimental strategies for fragment library screening using SPR biosensors ', bioRxiv, vol. 2020 . https://doi.org/10.1101/2020.12.23.424167مصطلحات موضوعية: Materials science, Fragment (computer graphics), Nanotechnology, Surface plasmon resonance biosensor, Biosensor
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المصدر: Journal of Medicinal Chemistry. 61:2292-2302
مصطلحات موضوعية: 0301 basic medicine, Kinetics, Protonation, Ligands, 01 natural sciences, Dissociation (chemistry), Structure-Activity Relationship, 03 medical and health sciences, Reaction rate constant, Computational chemistry, Carbonic anhydrase, Drug Discovery, Molecule, Surface plasmon resonance, Carbonic Anhydrase Inhibitors, Sulfonamides, biology, Chemistry, Proteins, Hydrogen-Ion Concentration, Surface Plasmon Resonance, 0104 chemical sciences, Zinc, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Drug Design, biology.protein, Thermodynamics, Molecular Medicine, Algorithms, Protein Binding, Protein ligand
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المؤلفون: Vladimir O. Talibov, Céleste Sele, Uwe Mueller, Wolfgang Knecht, E. Jagudin, G.M.A. Lima, Derek T. Logan, Maria Nyblom, Tove Sjögren
المصدر: Acta Crystallographica. Section D, Structural Biology
مصطلحات موضوعية: 0301 basic medicine, Research groups, Computer science, Crystallography, X-Ray, computer.software_genre, drug discovery, Automation, 03 medical and health sciences, 0302 clinical medicine, Software, Structural Biology, protein crystallography, BioMAX, User Facility, FragMAX, Throughput (business), Database, software, business.industry, Fragment (computer graphics), Data Collection, user facility, Proteins, fragment screening, Research Papers, high-throughput data analysis, Multiple data, 030104 developmental biology, Beamline, 030220 oncology & carcinogenesis, Protein Structural Elements, Inhouse research on structure dynamics and function of matter, business, computer
وصف الملف: application/pdf
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المؤلفون: Jie Nan, Anastasya Shilova, Johan Thånell, Christopher Ward, Robert Lizatović, Hamed Tarawneh, Thomas Ursby, Robert L. Shoeman, Antonio Milan-Otero, Antonio Bartalesi, Oskar Aurelius, Franz Hennies, Mikael Lundin, Yngve Cerenius, Mirko Milas, R. Bruce Doak, Julio Lidón-Simon, Vahid Haghighat, Frank Siewert, Mikel Eguiraun, E. Jagudin, G.M.A. Lima, Tobias Jeppsson, Ana Gonzalez, Ishkhan Gorgisyan, Thomas Eriksson, Marjolein M. G. M. Thunnissen, Alberto Nardella, Marco Kloos, Uwe Mueller, Anders Rosborg, Monika Bjelčić, Johan Unge, Andrea Gross, Vladimir O. Talibov, Fredrik Bolmsten, Roberto Appio, Brian Norsk Jensen, Ross J. Friel, Karl Åhnberg, Peter Sondhauss, Artur Barczyk
المصدر: Journal of Synchrotron Radiation
مصطلحات موضوعية: Nuclear and High Energy Physics, Scanner, Materials science, Instrumentation, MBA, micro-focus, remote operation, 010402 general chemistry, 01 natural sciences, law.invention, 03 medical and health sciences, Optics, macromolecular crystallography, law, serial crystallography, beamline, 030304 developmental biology, Monochromator, automation, 0303 health sciences, Radiation, business.industry, micro focus, Beamlines, Undulator, Sample (graphics), 0104 chemical sciences, Beamline, Computer data storage, business, Storage ring
وصف الملف: application/pdf
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المصدر: Carbonic Anhydrase as Drug Target ISBN: 9783030127787
مصطلحات موضوعية: Dissociation constant, Reaction rate constant, biology, Chemistry, Thermodynamic equilibrium, Computational chemistry, Carbonic anhydrase, biology.protein, Surface plasmon resonance, Kinetic energy, Biosensor, Dissociation (chemistry)
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المصدر: Journal of Medicinal Chemistry. 59:2083-2093
مصطلحات موضوعية: 0301 basic medicine, Protein family, Stereochemistry, Kinetics, 01 natural sciences, Isozyme, Dissociation (chemistry), Structure-Activity Relationship, 03 medical and health sciences, Carbonic anhydrase, Drug Discovery, Humans, Surface plasmon resonance, Carbonic Anhydrase Inhibitors, Carbonic Anhydrases, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Hydrogen-Ion Concentration, Fluorescence, Affinities, 0104 chemical sciences, Isoenzymes, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Chemical engineering, biology.protein, Molecular Medicine
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المؤلفون: A. A. Tikhonov, A. M. Schwartz, L V Putlyaeva, V. I. Butvilovskaya, M V Tsybulskaya, Alexey Y. Sazykin, Sergey Surzhikov, Vladimir O. Talibov, Olga N. Solopova, A. A. Stomakhin, Alla Rubina, P. V. Belousov
المصدر: Молекулярная биология. 49:790-799
مصطلحات موضوعية: animal structures, biology, medicine.diagnostic_test, medicine.drug_class, General Medicine, Serpin, Monoclonal antibody, Molecular biology, Epitope, law.invention, Antigen, law, Immunoassay, embryonic structures, Monoclonal, medicine, biology.protein, Recombinant DNA, Antibody
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16
المؤلفون: U. Helena Danielson, Vladimir O. Talibov, Christian Seeger
المصدر: Journal of Molecular Recognition
مصطلحات موضوعية: 0301 basic medicine, calmodulin, Calmodulin, Cations, Divalent, Kinetics, Gene Expression, 03 medical and health sciences, 0302 clinical medicine, calmodulin-dependent kinase, Structural Biology, Ca2+/calmodulin-dependent protein kinase, Animals, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Neurogranin, Surface plasmon resonance, Molecular Biology, Research Articles, Binding Sites, Sequence Homology, Amino Acid, biology, neurogranin, Microscale thermophoresis, Chemistry, Kinase, Biochemistry and Molecular Biology, Proteins, Affinities, microscale thermophoresis, Recombinant Proteins, calmodulin‐dependent kinase, 030104 developmental biology, Biochemistry, biology.protein, Thermodynamics, Calcium, Cattle, Sequence Alignment, 030217 neurology & neurosurgery, surface plasmon resonance, Biokemi och molekylärbiologi, Research Article, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Felipe Marques Souza de Oliveira, M Karoliina Hirvonen, Ola Söderberg, Johannes Haybaeck, Masood Kamali-Moghaddam, Linda Arngården, Liza Löf, Gaëlle Cane, Björn Koos, U. Helena Danielson, Manfred Auer, Carl-Magnus Clausson, Vladimir O. Talibov, Nhan T. Pham, Johan Heldin, Axel Klaesson, Karin Grannas
المصدر: Nature Communications
Koos, B, Cane, G, Grannas, K, Löf, L, Arngården, L, Heldin, J, Clausson, C-M, Klaesson, A, Hirvonen, M K, de Oliveira, F M S, Talibov, V O, Pham, N T, Auer, M, Danielson, U H, Haybaeck, J, Kamali-Moghaddam, M & Söderberg, O 2015, ' Proximity-dependent initiation of hybridization chain reaction ', Nature Communications, vol. 6, 7294 . https://doi.org/10.1038/ncomms8294مصطلحات موضوعية: Medicin och hälsovetenskap, Epidermal Growth Factor/chemistry, Oligonucleotides, General Physics and Astronomy, Sequence (biology), Plasma protein binding, Biology, 010402 general chemistry, Medical and Health Sciences, 01 natural sciences, Article, General Biochemistry, Genetics and Molecular Biology, Protein–protein interaction, Flow cytometry, 03 medical and health sciences, Nucleic acid thermodynamics, medicine, Fluorescent Dyes/chemistry, Oligonucleotides/chemistry, Fluorescent Dyes, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Epidermal Growth Factor, medicine.diagnostic_test, ErbB Receptors/chemistry, Oligonucleotide, Nucleic Acid Hybridization, Kemi, General Chemistry, Flow Cytometry, Molecular biology, Fluorescence, 0104 chemical sciences, 3. Good health, ErbB Receptors, Chemical Sciences, Biophysics, Chain reaction, Protein Binding
وصف الملف: application/pdf
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المؤلفون: V. V. Maslennikov, A. Yu. Rubina, N. Offermann, Guzel Feyzkhanova, Margrit Fooke-Achterrath, Ekaterina Dementieva, Yu. P. Reznikov, Vladimir O. Talibov, Alexander S. Zasedatelev, M A Filippova
المصدر: Journal of immunological methods. 406
مصطلحات موضوعية: Allergy, Chromatography, Chemistry, Immunology, Protein Array Analysis, Total ige, Fluorescent Antibody Technique, Hydrogels, Allergens, Immunoglobulin E, Serum samples, medicine.disease, Molecular biology, Quantitative determination, In vitro, Antibodies, Anti-Idiotypic, Protein microarray, medicine, Hypersensitivity, Immunology and Allergy, Humans, Antigens, Biochip, Skin Tests
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المؤلفون: A. Yu. Rubina, Alexander S. Zasedatelev, M. A. Filippova, M. Fooke-Achterrath, G. U. Feizkhanova, Vladimir O. Talibov
المصدر: Doklady. Biochemistry and biophysics. 447
مصطلحات موضوعية: Immunoassay, biology, Chemistry, Biophysics, General Chemistry, General Medicine, Computational biology, Biosensing Techniques, Equipment Design, Allergens, Immunoglobulin E, Immunologic Tests, medicine.disease_cause, Microarray Analysis, Biochemistry, Molecular biology, Equipment Failure Analysis, Allergen, Immunoglobulin G, medicine, biology.protein, Multiplex, Antibody, Biochip
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